In these frightening times, I am struck by the heroic and merciful acts I first encountered as a young child behind barbed wire.

Joe Castiglione saw his first baseball game in the Bronx.

Joe Castiglione saw his first baseball game in the Bronx.

Matt Tully was dedicated to his craft and to this community. The Matthew L. Tully Memorial Fund is a meaningful way to keep his memory and work alive.

The World Health Organization is once again facing increased scrutiny and outrage. The renewed public outcry is not, however, directed at the shoddy initial response to the ongoing global coronavirus pandemic, instead coming as a result of unsettling details recently discovered in the organization’s child and adolescent sexual education guidelines. Set forth by global health…

The post WHO Comes Under Fire for Saying Kids Under 4 Should Be Taught About ‘Early Childhood Masturbation’ appeared first on The Western Journal.

Monogenic forms of obesity have been identified in ≤10% of severely obese European patients. However, the overall spectrum of deleterious variants (point mutations and structural variants) responsible for childhood severe obesity remains elusive. In this study, we genetically screened 225 severely obese children from consanguineous Pakistani families through a combination of techniques including an in-house developed augmented whole-exome sequencing (CoDE-seq) enabling simultaneous detection of whole exome copy number variations (CNVs) and of point mutations in coding regions. We identified 110 probands (49%) carrying 55 different pathogenic point mutations and CNVs in 13 genes/loci responsible for non-syndromic and syndromic monofactorial obesity. CoDE-seq also identified 28 rare or novel CNVs associated with intellectual disability in 22 additional obese subjects (10%). Additionally, we highlight variants in candidate genes for obesity warranting further investigation. Altogether, 59% of the studied cohort are likely to have a discrete genetic cause with 13% of these due to CNVs demonstrating a remarkably higher prevalence of monofactorial obesity than hitherto reported and a plausible over lapping of obesity and intellectual disabilities in several cases. Finally, inbred populations with high prevalence of obesity, provide a unique genetically enriched material in quest of new genes/variants influencing energy balance.

Edwin A.M. Gale
Dec 1, 2002; 51:3353-3361
Perspectives in Diabetes

The UK government published its report Childhood Obesity: a Plan for Action, in August 2016. A new analysis article takes them to task for the inadequacy of that response to a growing problem. Neena Modi is a professor of neonatal medicine, at Imperial College London, and president of the Royal College of Paediatrics and Child Health, and joins...

Findings from a range of prospective cohort studies based around the world indicate that higher intelligence in children is related to a lower risk of all cause mortality in adulthood - and now a new study, published on bmj.com, is trying to dig into that association further, with a whole population cohort and data on cause specific...

In a British cohort, 30% of patients who had survived childhood cancer had died within 45 years of diagnosis; only 6% were expected to have died. 51% had developed a new primary cancer, but a 26% died of cardiovascular disease - thought to be caused by their treatment. Consequently, efforts to reduce long term mortality have focused on reducing...

OBJECTIVE

The MHC region harbors the strongest loci for latent autoimmune diabetes in adults (LADA); however, the strength of association is likely attenuated compared with that for childhood-onset type 1 diabetes. In this study, we recapitulate independent effects in the MHC class I region in a population with type 1 diabetes and then determine whether such conditioning in LADA yields potential genetic discriminators between the two subtypes within this region.

OBJECTIVE

On the basis of urinary steroidal gas chromatography-mass spectrometry (GC-MS), we previously defined a novel concept of a disease-specific "steroid metabolomic signature" and reclassified childhood obesity into five groups with distinctive signatures. The objective of the current study was to delineate the steroidal signature of insulin resistance (IR) in obese children.

Circulating levels of perfluorodecanoic acid, a type of perfluoroalkyl acid, may be associated with dental caries in children, according to a study published in the fall 2019 issue of the Journal of Public Health Dentistry.

For children in U.S. homes where a language other than English is spoken, early childhood programs that are responsive to their needs can be key to later academic success. But as states refine their Quality Rating and Improvement Systems (QRIS) to assess such programs, immigrant early childhood workers with in-demand language and cultural skills may be left behind. This report examines the challenges these workers face and promising practices to serve diverse communities.

Marking the release of an MPI report, this webinar examines the challenges and successes major host countries in Europe and North America are experiencing in providing high-quality early childhood education and care (ECEC) services for children from refugee and asylum seeker families.

Experts on this webinar discussed the effects of trauma on the development of young refugee children, and how early child-care programs can address these traumatic experiences. The discussion featured practical strategies that child-care providers in Canada are implementing to support refugee children and families. 

During this webinar, speakers discuss a MPI policy brief that explores the intersection of trauma and early childhood development, exploring how migration-related trauma and stressors can influence the wellbeing of young children of immigrants, and points to key opportunities for states to support, through early childhood and other programs.

As states work to build high-quality early childhood systems and implement the federal Workforce Innovation and Opportunity Act (WIOA) and Every Student Succeeds Act (ESSA), having detailed knowledge of the characteristics of immigrant parents can help maximize the effectiveness of programs that seek to improve child and family outcomes, as this commentary explains.

When I reread the Green Knowe books, what struck me most about them was how much time the children in the books - Tolly, Ping, Ida, Oskar, Susan,and Jacob spent exploring the outdoors. Tolly climbs the beech tree to pretend that he is a sailor boy on the mast of a ship:

OBJECTIVE

Previous studies suggested that childhood prediabetes may develop prior to obesity and be associated with relative insulin deficiency. We proposed that the insulin-deficient phenotype is genetically determined and tested this hypothesis by longitudinal modeling of insulin and glucose traits with diabetes risk genotypes in the EarlyBird cohort.

The first years of a child’s life are a time of immense growth, and exposure to trauma—if left unaddressed—can have significant, lifelong effects. This issue brief examines how young children of refugees and other immigrants may be affected by trauma, and what early childhood education and care programs, health-care providers, and others can do to mitigate its adverse effects.

During this webinar, speakers provide an overview of an MPI policy brief that seeks to raise awareness of the intersection of trauma and early childhood development, and how U.S. early childhood programs could more effectively address this trauma in young children in refugee and immigrant households. The participants discuss efforts to integrate trauma-informed approaches into early childhood systems and how home visiting services can effectively address trauma and mental health through a two-generation approach.

Democrat Gavin Newsom, who takes office Jan. 7, plans to expand full-day kindergarten and child-care offerings in the state, according to media reports.

Edinburgh : W. Green, 1908.

London : Rebman, 1901.

Many of us look back on our childhoods with warm feelings. But for more than 150 million girls and boys between the ages of 5 and 17 around the world, childhood means something else: poverty, a lack of education and working long hours in dangerous conditions.  

The Flint Water Crisis captured national attention about the dangers of lead contamination in public water supplies. Now, nearly six years after the problem was first detected, health officials are reporting on the well-being of children in Flint.

As a child, Fay Richardson wanted to dance, with the grace and movement of ballet captivating her. Now, at 79-years-old, she's doing just that.

Having a bachelor's degree, a top-notch grade point average, and a relatively high level of work experience actually reduce the chance that a job applicant will be called in for an interview with a child-care provider, concludes new research by Kent State and Arizona State universities.

New data show that a growing percentage of children, especially those from well-off households, attend center-based care in the year before they attend kindergarten.

There's a new focus on getting more training to early-childhood educators, but there's a dearth of information about what constitutes a high-quality, teacher-preparation program.

The Center for American Progress has released a set of recommendations for governors in 2019 that includes things such as full-day universal preschool and the study of pre-term births, which can cause learning difficulties.

Half of Americans in 22 states live in "child-care deserts"—places where there are more than three children for every child-care slot—according to a new geographic analysis by the Center on American Progress, a liberal think tank.

Without rigorous research that accurately reflects the current population, early education won't deliver for all students, write two education researchers.

Democrat Gavin Newsom, who takes office Jan. 7, plans to expand full-day kindergarten and child-care offerings in the state, according to media reports.

Federal funding for state-administered child-care-assistance programs has declined since 2001, leaving many low-income families struggling to find child care, finds a study by the National Women's Law Center.

Families may be less likely to take advantage of early-childhood education programs if they work nonstandard hours, finds a new report from the National Research Center on Hispanic Children and Families.

Education needs to stop going around in circles, writes Stanford’s Thomas S. Dee.

Waterford UPSTART, an online program that offers literacy and math enrichment lessons aimed at preschoolers, received support from a philanthropy dedicated to funding "bold ideas for social change."

The World Health Organization issued guidelines for children under 5, including its first recommendations on how much time children should be spending in front of a digital screen.

A new report by the Government Accountability Office provides the first comprehensive nationwide look at state early education programs and how they are funded.

Pediatric weight gain is a critical aspect of the obesity epidemic. Chronic stress produces physiologic perturbations capable of altering brain mechanisms related to eating as well as those implicated in self-regulatory behaviors.

We show that early childhood risk exposures are associated with weight gain in adolescence, independent of childhood BMI. We also find that deficiencies in self-regulatory processes help explain the link between chronic stress and adiposity. (Read the full article)

Overweight has been associated with an increased risk of asthma in children, although the published literature is contradictory. How change in overweight status during childhood affects asthma risk has not been well studied.

Among children whose weight has normalized, high BMI during the first 4 years of life does not increase the risk of asthma at school age. Current high BMI is associated with increased risk of asthma and sensitization to inhalant allergens. (Read the full article)

Traumatic brain injury in school-aged children is associated with intellectual, behavioral, and social deficits. Research into outcomes of children injured before 3 years of age is limited despite data suggesting a high incidence of injury in this age group.

Results show that a moderate to severe traumatic brain injury before 3 years of age is associated with lowered cognitive function. Furthermore, this study highlights the link between social disadvantage and poor outcomes after traumatic brain injury in early childhood. (Read the full article)

Epilepsy/seizure disorder is known to be associated with a range of mental health and neurodevelopmental comorbidities, based on clinical studies, and on population studies largely conducted outside the United States.

In a nationally representative sample of US children, estimated prevalence of reported lifetime epilepsy/seizure disorder was 1%, and of current epilepsy/seizure disorder was 6.3/1000. Developmental, mental health, and physical comorbidities are common, warranting enhanced surveillance, and an integrated service approach. (Read the full article)