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Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors

Org. Biomol. Chem., 2020, 18,3104-3116
DOI: 10.1039/D0OB00391C, Paper
Marc Pretze, Christin Neuber, Elisa Kinski, Birgit Belter, Martin Köckerling, Amedeo Caflisch, Jörg Steinbach, Jens Pietzsch, Constantin Mamat
Two new fluorine-18-labelled xanthine derivatives with high binding affinity were synthesised as PET-radioligand candidates for Eph receptors.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate

Org. Biomol. Chem., 2020, 18,3177-3189
DOI: 10.1039/D0OB00087F, Paper
Antonio Arcadi, Massimiliano Aschi, Marco Chiarini, Fabio Marinelli, Vincenzo Marsicano, Gustavo Portalone
The selective formation of quinazoline vs. benzoxazine  and benzothiazine derivatives from β-(2-aminophenyl)-α,β-ynones and aryl isocyanates/benzoyl isothiocyanate was explored. DFT calculations provide a plausible rationale.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Construction of 2,3-disubstituted benzo[b]thieno[2,3-d]thiophenes and benzo[4,5]selenopheno[3,2-b]thiophenes using the Fiesselmann thiophene synthesis

Org. Biomol. Chem., 2020, 18,3164-3168
DOI: 10.1039/D0OB00300J, Paper
Roman A. Irgashev, Nadezhda S. Demina, Gennady L. Rusinov
A number of 2,3-disubstituted benzo[b]thieno[2,3-d]thiophenes and benzo[4,5]selenopheno[3,2-b]thiophenes have been obtained using a convenient approach based on the Fiesselmann thiophene synthesis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00534G, Paper
Kai Gruhle, Max Tuchtenhagen, Sindy Müller, Gerd Hause, Annette Meister, Simon Drescher
The synthesis of six single-chain, alkyl-branched bolalipids and first investigations of the lyotropic behaviour of these lipids are reported.
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Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00136H, Communication
Pedro López-Mendoza, Luis D. Miranda
A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.
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Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00629G, Communication
Marcos R. Scheide, Alex R. Schneider, Guilherme A. M. Jardim, Guilherme M. Martins, Daniele C. Durigon, Sumbal Saba, Jamal Rafique, Antonio L. Braga
Herein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives.
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Visible light promoted continuous flow photocyclization of 1,2-diketones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00532K, Paper
Francesco Secci, Stefania Porcu, Alberto Luridiana, Angelo Frongia, Pier Carlo Ricci
A continuous flow Norrish–Yang photocyclization of 1,2-diketones has been developed and applied to the synthesis of functionalized 2-hydroxycyclobutanones, under blue light irradiation.
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N-Hydroxy peptides: solid-phase synthesis and β-sheet propensity

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00664E, Paper
Matthew P. Sarnowski, Juan R. Del Valle
Backbone amide hydroxylation of peptide strands enhances β-hairpin folding.
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Acylation of oxindoles using methyl/phenyl esters via mixed Claisen condensation – An access to 3-alkylideneoxindoles

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00789G, Communication
Ramdas Sreedharan, Purushothaman Rajeshwaran, Pradeep Kumar Reddy Panyam, Saurabh Yadav, C. M. Nagaraja, THIRUMANAVELAN GANDHI
Predominantly, aggressive acid chlorides and stoichiometric coupling reagents are employed in the acylating process for synthesizing carbonyl tethered heterocycles. Herein, we report simple acyl sources, viz. methyl and phenyl esters...
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The key entity of a DCAR agonist, phosphatidylinositol mannoside Ac1PIM1: its synthesis and immunomodulatory function

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/C9OB02724F, Communication
Yohei Arai, Shota Torigoe, Takanori Matsumaru, Sho Yamasaki, Yukari Fujimoto
We achieved the first synthesis of phosphatidylinositol mannoside Ac1PIM1, and a very potent agonist of an innate immune receptor DCAR is demonstrated.
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Donor–acceptor fluorophores as efficient energy transfer photocatalysts for [2 + 2] photodimerization

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/C9OB02735A, Paper
Qing-An Wu, Feng Chen, Chen-Chao Ren, Xue-Fen Liu, Hao Chen, Liang-Xuan Xu, Xiao-Cong Yu, Shu-Ping Luo
Donor–acceptor fluorophores can act as efficient energy transfer photocatalysts to activate enone substrates, realizing photodimerization and isomerization reaction of enone substrates without precious metal photocatalysts.
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Synthesis of unsymmetrical benzils via palladium-catalysed α-arylation–oxidation of 2-hydroxyacetophenones with aryl bromides

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00575D, Paper
Open Access
Takanori Matsuda, Souta Oyama
Unsymmetrical benzils are synthesised by a one-pot tandem palladium-catalysed α-arylation and oxidation of 2-hydroxyacetophenones with aryl bromides.
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Copper(I)/Ganphos catalysis: enantioselective synthesis of diverse spirooxindoles using iminoesters and alkyl substituted methyleneindolinones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00546K, Paper
Hao Cui, Ke Li, Yue Wang, Manman Song, Congcong Wang, Donghui Wei, Er-Qing Li, Zheng Duan, François Mathey
A copper/Ganphos-catalyzed asymmetric 1,3-dipolar cycloaddition of glycine iminoesters with alkyl substituted 3-methylene-2-oxindoles is described, producing the spiro[pyrrolidin-3,3'-oxindole]s in good yields with high ee.
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Blue emissive dimethylmethylene-bridged triphenylamine derivatives appending cross-linkable groups

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00622J, Paper
Kangyu Zhou, Hongfei Pan, Yongjie Zhang, Houchen Wang, Xiaofei Dong, Xiangkui Ren, Xianggao Li, Shirong Wang, Zhijian Chen
Blue-emissive and cross-linkable dimethylmethylene-bridged triphenylamine derivatives were synthesized and their optical and electrochemical properties were investigated.
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Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00718H, Paper
Amol Sonawane, Atsushi Shimozuma, Taro Udagawa, Masayuki Ninomiya, Mamoru Koketsu
In this paper, we report the novel synthesis of three different heterocycles namely 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives from the corresponding 2,3-dichloroquinoxaline and 2,3-dichloropyrazine derivatives. Further, photophysical properties were investigated...
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Synthesis, structures and photophysical properties of hexacoordinated organosilicon compounds with 2-(2-pyridyl)phenyl groups

Org. Biomol. Chem., 2020, 18,3239-3242
DOI: 10.1039/D0OB00484G, Communication
Shohei Furuta, Toshiaki Mori, Yusuke Yoshigoe, Kohei Sekine, Yoichiro Kuninobu
We synthesised novel air-, water-, heat-, acid-, and base-stable hexacoordinated organosilicon compounds, which contain two C,N-bidentate ligands and form two silafluorene equivalent moieties, with Lewis acid–base interactions.
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Phenylboronic acid-catalyzed tandem construction of S–S and C–S bonds: a new method for the synthesis of benzyl disulfanylsulfone derivatives from S-benzyl thiosulfonates

Org. Biomol. Chem., 2020, 18,3243-3248
DOI: 10.1039/D0OB00442A, Communication
Raju Jannapu Reddy, Md. Waheed, Gamidi Rama Krishna
A novel and unique phenylboronic acid-catalyzed tandem construction of S–S and C–S bonds via dimerization–sulfonylation has been disclosed for the synthesis of benzyl disulfanylsulfone derivatives.
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Synthesis of phenanthridines by I2-mediated sp3 C–H amination

Org. Biomol. Chem., 2020, 18,3312-3323
DOI: 10.1039/D0OB00433B, Paper
Benyao Fang, Jiao Hou, Jinyue Tian, Wenquan Yu, Junbiao Chang
An I2-mediated transition-metal-free sp3 C–H amination reaction is established for phenanthridine synthesis in an efficient and scalable manner.
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Copper-catalyzed direct amination of benzylic hydrocarbons and inactive aliphatic alkanes with arylamines

Org. Biomol. Chem., 2020, 18,3263-3268
DOI: 10.1039/D0OB00491J, Communication
Hua Yao, Bo Xie, Xiaoyang Zhong, Shengzhou Jin, Sen Lin, Zhaohua Yan
A new synthetic method toward direct C–N bond formation through saturated C–H amination of benzylic hydrocarbons and inactive aliphatic alkanes with primary aromatic amines under an inexpensive catalyst/oxidant (Cu/DTBP) system has been developed.
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Correction: Synthetic-biology-based discovery of a fungal macrolide from Macrophomina phaseolina

Org. Biomol. Chem., 2020, 18,3392-3392
DOI: 10.1039/D0OB90051F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yohei Morishita, Terutaka Sonohara, Tohru Taniguchi, Kiyohiro Adachi, Makoto Fujita, Teigo Asai
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Late-stage synthesis and application of photoreactive probes derived from direct benzoylation of heteroaromatic C–H bonds

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00336K, Communication
Kevin D. Hesp, Jun Xiao, Graham M. West
A synthetically-driven, late-stage C–H benzoylation strategy for the expedited preparation and evaluation of heterocyclic alternatives to more classical benzophenone photoreactive probes is reported.
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Spiroconyone A, a new phytosterol with a spiro [5,6] ring system from Conyza japonica

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00666A, Paper
Long-Gao Xiao, Yu Zhang, Hong-Li Zhang, Ding Li, Qiong Gu, Gui-Hua Tang, Qian Yu, Lin-Kun An
The first rearranged phytosterol (spiroconyone A) with an unusual spiro [5,6] ring system and two new TDP1 inhibitors 7 and 10 showing a strong synergistic effect with topotecan were isolated from Conyza japonica.
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Correction: Nickel-catalyzed cyanation of phenol derivatives activated by 2,4,6-trichloro-1,3,5-triazine

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB90052D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Liang Wang, Yaoyao Wang, Jun Shen, Qun Chen, Ming-Yang He
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Apple announces new iPhone SE 2020, to come with minimum 64 GB storage

It has the same iPhone 8 design, but the camera and processor are new.




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Folklife News & Events: James Hogg: Scotland's Shepherd Poet Symposium

Please join us for an afternoon symposium:

James Hogg: Scotland's Shepherd Poet
February 21, 2020 1:00 pm - 6:00 pm
Whittall Pavilion, Thomas Jefferson Building, Library of Congress

This symposium will explore the work of James Hogg, “The Ettrick Shepherd” (1770-1835), an influential Scottish song-maker, folklore collector, novelist, and poet. Inspired by Robert Burns, colleague of Walter Scott, and friend of Lord Byron, Hogg played a major role in creating and promoting Scottish culture, within Scotland and internationally.

This free event, which is open to the public, will compare his work with that of more recent American performers and collectors, who also served as intermediaries between the worlds of folk, popular, and literary culture for the first time. Speakers will explore issues around field collecting, song transmission and creation over the past three centuries. An afternoon of presentations and discussions will be capped by a performance featuring renowned singer Sheena Wellington, who has recorded and performed some of Hogg’s best known songs.

Request ADA accommodations five days in advance at 202-707-6362 or ADA@loc.gov

Find further information at the link!




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[ASAP] Controlling Surface Phase Transition and Chemical Reactivity of O3-Layered Metal Oxide Cathodes for High-Performance Na-Ion Batteries

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00700




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How your smartphone became poll-savvy

On the Neta app, which describes itself as “Leaders ka report card”, users can also share their opinion in the form of video reviews and comments, tag their MLA and conduct polls, with the most active users being highlighted in a separate section called ‘star citizens’




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Self-consolidating concrete: applying what we know / Joseph A. Daczko

Barker Library - TA442.5.D33 2012




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Fiber reinforced concrete for sustainable structures: at the Fall 2012 ACI Convention and the Fall 2013 ACI Convention: Toronto, Ontario, Canada, 21-25 October 2012, Phoenix, Arizona, USA, 10-24 October 2013.

Barker Library - TA444.F53 2015




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Successful women ceramic and glass scientists and engineers: 100 inspirational profiles / Lynnette D. Madsen, Ph.D.

Hayden Library - TP805.M33 2016




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Eco-efficient and sustainable concrete incorporating recycled post-consumer and industrial byproducts: held at the ACI Fall 2013 Convention, Phoenix, Arizona, USA, 20-24 October 2013 / Editor: Moncef L. Nehdi

Barker Library - TA441.E286 2013




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Reduction of crack width with fiber: held at the ACI Fall 2016 Convention, Philadelphia, Pennsylvania, USA, 23-24 October 2016 / editors, Corina-Maria Aldea, Mahmut Ekenel

Barker Library - TA444.R43 2016




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Sulfate attack on concrete: a holistic perspective: held at the ACI Fall 2016 Convention: Philadelphia, Pennsylvania: USA, 23-24 October 2016 / editors, Mohamed T. Bassuoni, R. Doug Hooten, Thanos Drimalas

Barker Library - TA440.S85 2017




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Advances in cement analysis and concrete petrography / editors, Derek Cong and Don Broton

Barker Library - TA435.A36 2019




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Stem cells: biology and engineering / Phuc Can Pham, editor

Online Resource




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Integrative structural biology with hybrid methods / editors, Haruki Nakamura, Gerard Kleywegt, Stephen K. Burley and John L. Markley

Online Resource




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Biochemical and biophysical roles of cell surface molecules / Kausik Chattopadhyay, Subhash C. Basu, editor

Online Resource




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The Lysenko controversy as a global phenomenon: genetics and agriculture in the Soviet Union and beyond / William deJong-Lambert, Nikolai Krementsov, editors

Hayden Library - QH429.2.L97 L975 2017




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Semiconductor lasers and diode-based light sources for biophotonics / edited by Peter E. Andersen, Paul Michael Petersen

Online Resource




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Introduction to cellular biophysics. Armin Kargol

Online Resource




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Advances in heart valve biomechanics: valvular physiology, mechanobiology, and bioengineering / Michael S. Sacks, Jun Liao, editors

Online Resource




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Reading nature: engaging biology students with evidence from the living world / Matthew Kloser, Sophia Grathwol

Hayden Library - QH315.K545 2018




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Reordering life: knowledge and control in the genomics revolution / Stephen Hilgartner

Hayden Library - QH447.H554 2017




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Gene machine: the race to decipher the secrets of the ribosome / Venki Ramakrishnan

Hayden Library - QH442.R244 2018




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Bringing biology to life: an introduction to the philosophy of biology / Mahesh Ananth

Hayden Library - QH331.A49 2018




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Philosophy of biology before biology / Cécilia Bognon-Küss & Charles T. Wolfe

Hayden Library - QH305.B617 2019




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Extracellular sugar-based biopolymers matrices Ephraim Cohen, Hans Merzendorfer, editors

Online Resource




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Molecular Biology edited by Stephen H Howell

Online Resource




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Encyclopedia of biophysics / editors, Gordon Roberts, Anthony Watts ; European Biophysical Societies

Online Resource




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Theoretical physics for biological systems / Paola Lecca, Researcher, Department of Mathematics, University of Trento, Italy, Angela Re, Postdoctoral Fellow, Center for Sustainable Future Technologies CSFT@Polito, Istituto Italiano di Tecnologia, Italy

Hayden Library - QH505.L397 2019