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Australia's biggest state to ease coronavirus lockdown from May 15

Australia's most populous state, home to Sydney, will allow restaurants, playgrounds and outdoor pools to reopen on Friday as extensive testing has shown the spread of the coronavirus has slowed sharply, New South Wales state's premier said on Sunday.




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Anurag Basu Wanted Irrfan Khan To Play Ranbir Kapoor's Father In Jagga Jasoos!

Anurag Basu and Irrfan Khan had worked together for the 2007 film Life...In A Metro. Recently, while speaking with Mumbai Mirror, the filmmaker revealed that he was working on a sequel to the film with Irrfan. While revealing that




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Jaggery For Weight Loss: How Does It Help?

Jaggery is a natural sweetener, that has become increasingly popular in recent years due to its role in replacing sugar. A combination of health and taste, jaggery has been used in Indian cuisine since ages. Often referred to as




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Mangoes off the menu for lonely primates, as Kiev zoo struggles in lockdown

Mykhailo Pinchuk takes a short walk around his empty zoo, greeting some animals with a stroke and a morsel of food.




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From beacon fire to radio (Masters of space): the story of long-distance communication / by Walter Kellogg Towers

Archives, Room Use Only - TK5115.T69 1924




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Chris Pratt praises 'Pretty damn good' haircut by wife Katherine Schwarzenegger




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Surat police detains Congress leaders for flagging off train for migrant workers




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Gas leak at LG Polymers plugged: Andhra Police Chief




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Google-haggle

A little over a month ago, when Google made defiant noises of shutting down its office in China, the stand-off was phrased with great fanfare as the new clash of civilisations.




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Study suggests sleep disturbances among infants may lead to altered brain development




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Nick Saban explains differences in Jerry Jeudy, Raiders' Henry Ruggs

Nick Saban doesn't want to choose between his two best wide receivers from a year ago.




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Check out the world's biggest 3D printed building!

The two-storey 6,900 square foot structure will be used as an office for general administrative functions by the Dubai Municipality.It was designed in collaboration with Apis Cor, a 3D printing and construction company in Boston.




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With 1,752 cases, India sees biggest single-day jump

A total of 37 deaths were reported since Thursday evening of which 14 fatalities were reported from Maharashtra, nine from Gujarat, three from Uttar Pradesh, two each from Andhra Pradesh, Delhi, Madhya Pradesh,Tamil Nadu and Telengana and one from Karnataka, ministry data stated.




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Houseboat sector struggling to stay afloat

Owners say it will take a year to bring the tourism sector back on track




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Dental hostel tagged containment zone

Dental hostel tagged containment zone




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Smuggled items seized

Smuggled items seized




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289 workers quarantined in Shivamogga district

As many as 289 migrant workers from Shivamogga district working outside the State who have returned to their native areas in the past one week have be




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B’day party trigger for 45 cases in LB Nagar

B’day party trigger for 45 cases in LB Nagar




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B'day party trigger for corona cases in LB Nagar

B'day party trigger for corona cases in LB Nagar




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Punjab Police expose Pak links in powerful nexus of narcotics smuggling, hawala transaction




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Landing of 90,000 NRIs in Punjab triggers coronavirus scare




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Medical experts suggest COVID-19 would peak in India by mid-September, 58pc Indian to get infected: Punjab CM




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Punjab CM suggests extension of national lockdown at PM's video conference




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Three arrested in Punjab for smuggling liquor amid lockdown




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Punjab CM asks opposition not to trigger panic




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Policeman dragged on bonnet in Punjab amid lockdown




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Punjab police arrests biggest drug smuggler from Sirsa




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Two drug smugglers arrested from Sirsa: Punjab DGP




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Drug smuggler with Hizbul links arrested in Punjab




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Worker’s death triggers panic

Though he tested negative for COVID-19, staff seek compensation




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Hyderabad: Birthday party trigger for 45 coronavirus cases in LB Nagar




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How to make eggless chocolate mousse

Recipes by chef Ashok Suyal, pastry chef at Jaypee Greens Golf and Spa Resort, Greater Noida.




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Coherent Bragg imaging of 60 nm Au nanoparticles under electrochemical control at the NanoMAX beamline

Nanoparticles are essential electrocatalysts in chemical production, water treatment and energy conversion, but engineering efficient and specific catalysts requires understanding complex structure–reactivity relations. Recent experiments have shown that Bragg coherent diffraction imaging might be a powerful tool in this regard. The technique provides three-dimensional lattice strain fields from which surface reactivity maps can be inferred. However, all experiments published so far have investigated particles an order of magnitude larger than those used in practical applications. Studying smaller particles quickly becomes demanding as the diffracted intensity falls. Here, in situ nanodiffraction data from 60 nm Au nanoparticles under electrochemical control collected at the hard X-ray nanoprobe beamline of MAX IV, NanoMAX, are presented. Two-dimensional image reconstructions of these particles are produced, and it is estimated that NanoMAX, which is now open for general users, has the requisites for three-dimensional imaging of particles of a size relevant for catalytic applications. This represents the first demonstration of coherent X-ray diffraction experiments performed at a diffraction-limited storage ring, and illustrates the importance of these new sources for experiments where coherence properties become crucial.




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In-depth analysis of subclass-specific conformational preferences of IgG antibodies

An extended analysis of structural ensembles obtained from small-angle X-ray scattering data reveals subclass-specific conformational preferences of IgG antibodies, which are largely determined by the hinge-region structure.











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Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder

Ependymin was first discovered as a predominant protein in brain extracellular fluid in fish and was suggested to be involved in functions mostly related to learning and memory. Orthologous proteins to ependymin called ependymin-related proteins (EPDRs) have been found to exist in various tissues from sea urchins to humans, yet their functional role remains to be revealed. In this study, the structures of EPDR1 from frog, mouse and human were determined and analyzed. All of the EPDR1s fold into a dimer using a monomeric subunit that is mostly made up of two stacking antiparallel β-sheets with a curvature on one side, resulting in the formation of a deep hydrophobic pocket. All six of the cysteine residues in the monomeric subunit participate in the formation of three intramolecular disulfide bonds. Other interesting features of EPDR1 include two asparagine residues with glycosylation and a Ca2+-binding site. The EPDR1 fold is very similar to the folds of bacterial VioE and LolA/LolB, which also use a similar hydrophobic pocket for their respective functions as a hydrophobic substrate-binding enzyme and a lipoprotein carrier, respectively. A further fatty-acid binding assay using EPDR1 suggests that it indeed binds to fatty acids, presumably via this pocket. Additional interactome analysis of EPDR1 showed that EPDR1 interacts with insulin-like growth factor 2 receptor and flotillin proteins, which are known to be involved in protein and vesicle translocation.




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Small-angle neutron scattering studies suggest the mechanism of BinAB protein internalization

Small-angle neutron scattering (SANS) is one of the most widely used neutron-based approaches to study the solution structure of biological macromolecular systems. The selective deuterium labelling of different protein components of a complex provides a means to probe conformational changes in multiprotein complexes. The Lysinibacillus sphaericus mosquito-larvicidal BinAB proteins exert toxicity through interaction with the receptor Cqm1 protein; however, the nature of the complex is not known. Rationally engineered deuterated BinB (dBinB) protein from the L. sphaericus ISPC-8 species was synthesized using an Escherichia coli-based protein-expression system in M9 medium in D2O for `contrast-matched' SANS experiments. SANS data were independently analysed by ab initio indirect Fourier transform-based modelling and using crystal structures. These studies confirm the dimeric status of Cqm1 in 100% D2O with a longest intramolecular vector (Dmax) of ∼94 Å and a radius of gyration (Rg) of ∼31 Å. Notably, BinB binds to Cqm1, forming a heterodimeric complex (Dmax of ∼129 Å and Rg of ∼40 Å) and alters its oligomeric status from a dimer to a monomer, as confirmed by matched-out Cqm1–dBinB (Dmax of ∼70 Å and Rg of ∼22 Å). The present study thus provides the first insight into the events involved in the internalization of larvicidal proteins, likely by raft-dependent endocytosis.




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Bragg Edge Analysis for Transmission Imaging Experiments software tool: BEATRIX

BEATRIX, is a new tool for performing data analysis of energy-resolved neutron-imaging experiments involving intense fitting procedures of multi-channel spectra. The use of BEATRIX is illustrated for a test specimen, providing spatially resolved 2D maps for residual strains and Bragg edge heights.




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Unit-cell response of tetragonal hen egg white lysozyme upon controlled relative humidity variation

The effects of relative humidity on a tetragonal crystal form of hen egg white lysozyme are studied via in situ laboratory X-ray powder diffraction.




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Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals affected by solution state

Neutron crystal structure analysis of hen egg-white lysozyme hydrogen/deuterium exchanged before crystallization were performed by the joint X-ray and neutron refinement. The differences in hydrogen/deuterium exchange behavior between this study and previous ones were observed.




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Drugged spiders’ web spinning may hold keys to understanding animal behavior

“Spinning under the influence” is one way to describe recent activities in the Costa Rican laboratory of Smithsonian scientist William Eberhard. An entomologist at the Smithsonian’s Tropical Research Institute, Eberhard recently carried out a series of experiments in which he observed the web-building behavior of dozens of spiders under the influence of drugs—specifically, a chemical injected into their bodies by parasitic wasps.

The post Drugged spiders’ web spinning may hold keys to understanding animal behavior appeared first on Smithsonian Insider.




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Mergers of dense stellar remnants are likely trigger for many supernovae

The results show mergers of two dense stellar remnants are the likely cause of many of the supernovae that have been used to measure the accelerated expansion of the universe.

The post Mergers of dense stellar remnants are likely trigger for many supernovae appeared first on Smithsonian Insider.




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Newly discovered prehistoric turtle co-existed with world’s biggest snake

About as thick as a standard dictionary, this turtle’s shell may have warded off attacks by the Titanoboa, thought to have been the world’s biggest snake, and by other, crocodile-like creatures living in its neighborhood 60 million years ago.

The post Newly discovered prehistoric turtle co-existed with world’s biggest snake appeared first on Smithsonian Insider.




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Work of 19th-century oologists enables researcher to track climate change with duck eggs

BROOKINGS, S.D. — Julie DeJong can’t set foot on the ground of an Oregon marsh to gather duck eggs on a spring day in 1875. […]

The post Work of 19th-century oologists enables researcher to track climate change with duck eggs appeared first on Smithsonian Insider.