Mexican President Andres Manuel Lopez Obrador said on Friday he aims to present plans next week to reopen the economy, as key sectors like carmaking look to begin business again after over a month of quarantine measures to curb the coronavirus outbreak.

* Tourism, travel, hospitality business hit the hardest by COVID

With MLS players starting to return to their teams' respective training facilities, the league is considering a resumption of the season in June or July, with the possibility of all games in Orlando at the outset, the Washington Post reported.

Title: Health Tip: Risk Factors for Gestational Diabetes
Category: Health News
Created: 5/2/2008 2:00:00 AM
Last Editorial Review: 5/2/2008 12:00:00 AM

Title: FDA Puts Tough Warning Label on Ambien, Lunesta, Other Sleep Aids
Category: Health News
Created: 4/30/2019 12:00:00 AM
Last Editorial Review: 5/1/2019 12:00:00 AM

A new consensus document provides guidance on the safe reintroduction of cardiovascular procedures and testing derailed by the COVID-19 pandemic.

These are the coronavirus stories you need to know about today.

We describe an atypical pediatric case of immunoglobulin A vasculitis (IgAV), also referred to as Henoch-Schönlein purpura, in which formation of spontaneous hematoma of the paraspinal muscles developed. Spontaneous or unprovoked hematomas rarely occur in IgAV. These manifestations have not been described specifically in the pediatric literature as coinciding with IgAV. These findings are alarming for nonaccidental trauma, particularly in a patient without underlying blood dyscrasia. Our objective for this report is to highlight the possible association of muscular hematoma formation with IgAV and to help providers consider this association when trauma and hemophilia has been ruled out.

Influenza D virus (IDV) was initially isolated in the United States in 2011. IDV is distributed worldwide and is one of the causative agents of the bovine respiratory disease complex (BRDC), which causes high morbidity and mortality in feedlot cattle. The molecular mechanisms of IDV pathogenicity are still unknown. Reverse genetics systems are vital tools not only for studying the biology of viruses, but also for use in applications such as recombinant vaccine viruses. Here, we report the establishment of a plasmid-based reverse genetics system for IDV. We first verified that the 3'-terminal nucleotide of each 7-segmented genomic RNA contained uracil (U), contrary to previous reports, and we were then able to successfully generate recombinant IDV by cotransfecting 7 plasmids containing these genomic RNAs along with 4 plasmids expressing polymerase proteins and nucleoprotein into human rectal tumor 18G (HRT-18G) cells. The recombinant virus had a growth deficit compared to the wild-type virus, and we determined the reason for this growth difference by examining the genomic RNA content of the viral particles. We found that the recombinant virus incorporated an unbalanced ratio of viral RNA segments into particles compared to that of the wild-type virus, and thus we adjusted the amount of each plasmid used in transfection to obtain a recombinant virus with the same replicative capacity as the wild-type virus. Our work here in establishing a reverse genetics system for IDV will have a broad range of applications, including uses in studies focused on better understanding IDV replication and pathogenicity, as well as in those contributing to the development of BRDC countermeasures.

IMPORTANCE The bovine respiratory disease complex (BRDC) causes high mortality and morbidity in cattle, causing economic losses worldwide. Influenza D virus (IDV) is considered to be a causative agent of the BRDC. Here, we developed a reverse genetics system that allows for the generation of IDV from cloned cDNAs and the introduction of mutations into the IDV genome. This reverse genetics system will become a powerful tool for use in studies related to understanding the molecular mechanisms of viral replication and pathogenicity and will also lead to the development of new countermeasures against the BRDC.

One factor that contributes to the high prevalence of fetal alcohol spectrum disorder (FASD) is binge-like consumption of alcohol before pregnancy awareness. It is known that treatments are more effective with early recognition of FASD. Recent advances in retrospective motion correction for the reconstruction of three-dimensional (3D) fetal brain MRI...

Purpose:

Excess weight gain during pregnancy is at epidemic proportions, and pregnancy complications are also on the rise. We sought to determine whether better weight gain counseling of expectant mothers will improve obstetric outcomes.

Functions of eukaryotic mRNAs are characterized by intramolecular interactions between their ends. We have addressed the question whether 5' and 3' ends meet by diffusion-controlled encounter "through solution" or by a mechanism involving the RNA backbone. For this purpose, we used a translation system derived from Drosophila embryos that displays two types of 5'–3' interactions: Cap-dependent translation initiation is stimulated by the poly(A) tail and inhibited by Smaug recognition elements (SREs) in the 3' UTR. Chimeric RNAs were made consisting of one RNA molecule carrying a luciferase coding sequence and a second molecule containing SREs and a poly(A) tail; the two were connected via a protein linker. The poly(A) tail stimulated translation of such chimeras even when disruption of the RNA backbone was combined with an inversion of the 5'–3' polarity between the open reading frame and poly(A) segment. Stimulation by the poly(A) tail also decreased with increasing RNA length. Both observations suggest that contacts between the poly(A) tail and the 5' end are established through solution, independently of the RNA backbone. In the same chimeric constructs, SRE-dependent inhibition of translation was also insensitive to disruption of the RNA backbone. Thus, tracking of the backbone is not involved in the repression of cap-dependent initiation. However, SRE-dependent repression was insensitive to mRNA length, suggesting that the contact between the SREs in the 3' UTR and the 5' end of the RNA might be established in a manner that differs from the contact between the poly(A) tail and the cap.

Transportation infrastructure owners manage an array of different asset types such as bridges, road pavements, earthworks and drainage. Currently, most organization management procedures are siloed by asset type; however, there are important interactions between these asset groups that need to be managed in a cross-asset way. Although these interactions are known, there is little or no quantification of these interactions. For the first time, this paper quantifies that 74% of Highways England's earthwork failures are a result of drainage-related problems, either the lack of drainage infrastructure or the poor performance of it. The analysis undertaken is an important first step not only in moving towards more connected asset management planning for earthworks and drainage, but to also provide guidance for other owners of earthwork infrastructure assets to improve their strategic asset management procedures.

Thematic collection: This article is part of the Ground-related risk to transportation infrastructure collection available at https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure

BackgroundIn the context of a variable condition such as asthma, patient recognition of deteriorating control and knowing what prompt action to take is crucial. Yet, implementation of recommended self-management strategies remains poor.AimTo explore how patients with asthma and parents/carers of children with asthma develop and establish recommended self-management strategies for living with asthma, and how clinicians can best support the process.Design and settingA qualitative study in UK primary care.MethodPatients with asthma and parents/carers of children with asthma from 10 general practices were purposively sampled (using age, sex, and duration of asthma) to participate in focus groups or interviews between May 2016 and August 2016. Participants’ experiences of health care, management of asthma, and views on supported self-management were explored. Interviews and focus group sessions were audio-recorded and transcribed verbatim. Iterative thematic analysis was conducted, guided by the research questions and drawing on habit theory in discussion with a multidisciplinary research team.ResultsA total of 49 participants (45 patients; 4 parents/carers) took part in 32 interviews and five focus groups. Of these, 11 reported using an action plan. Patients learnt how to self-manage over time, building knowledge from personal experience and other sources, such as the internet. Some regular actions, for example, taking medication, became habitual. Dealing with new or unexpected scenarios required reflective abilities, which may be supported by a tailored action plan.ConclusionPatients reported learning intuitively how to self-manage. Some regular actions became habitual; dealing with the unexpected required more reflective cognitive skills. In order to support implementation of optimal asthma self- management, clinicians should consider both these aspects of self-management and support, and educate patients proactively.

The T1D Exchange established a learning platform by evaluating the current state of care and engaging 10 diabetes clinics in collaborative quality improvement (QI) activities. Participating clinics are sharing data and best practices to improve care delivery for people with type 1 diabetes. This article describes the design and initial implementation of this platform, known as the T1D Exchange Quality Improvement Collaborative. This effort has laid a foundation for learning from variation in type 1 diabetes care delivery via QI methodology and has demonstrated success in improving processes through iterative testing cycles and transparent sharing of data.

Nhà vườn, homestay từng nở rộ cách đây chục năm trước và bắt đầu thoái trào trong khoảng 2-3 năm trở lại đây. Tuy nhiên, trong mùa dịch Covid-19, nhiều người lại nhen nhóm ý định lùng mua đất làm nhà vườn để có chốn “nương náu”. Vậy phải làm sao để không hối tiếc khi mua đất làm nhà vườn?

A recent survey conducted by KB Financial Group Research Institute on 400 South Korean billionaires showed Vietnam is the most preferred country for real estate investments.

The trade war between the United States and China has turned real estate investors' interest to Southeast Asian countries, in which the Vietnamese industrial market emerges as a bright spot in the region.

On October 15, Batdongsan.com.vn released Hanoi Real Estate Market Report for Q3/2019, reporting that the asking price and growth rate of Hanoi market are lower than that of Ho Chi Minh City.

According to Batdongsan.com.vn’s real estate market report, the third quarter (Q3) of 2019 continued to witness the excitement of many Northern provincial markets. The number of listings and the interest level of users in these provinces and cities have increased sharply.

[Having appointment with real estate experts #5] While buying a home is quite easy for high-income households, it is another story for the middle-class. With a wise and specific financial plan, the chances of owning a home can still lie within reach even if an average income.

In the third quarter of 2019, condotel and resort villa market saw both supply and consumption falling by double digits since the ‘Ghost month’ made investors hesitate.

Real estate insiders and experts said it is essential to develop strict penalties to combat those operating fraudulent property businesses to protect the legitimate rights of consumers and legitimate enterprises.

According to Batdongsan.com.vn’s real estate market report for the third quarter (Q3) of 2019, besides the attraction of traditional markets, resort real estate segment is witnessing the rise of emerging markets. Notably, Hanoi investors overwhelmed in term of the number of searches for resort real estate on the website.

Premier industry experts also share an overview of the first quarter of the year, as well as brief market forecasts.

Far Homestay được xây dựng cho cặp đôi mới cưới với mong muốn về một ngôi nhà ven biển vừa để ở, vừa để làm homestay. Giải pháp thiết kế do D1 đưa ra không chỉ đáp ứng nhu cầu của chủ nhà mà còn cho phép tận dụng tối đa cảnh quan tự nhiên xung quanh, đồng thời đảm bảo sự riêng tư cho mọi người trong nhà.

As home sellers commonly propose to state a lower price in the sale contract than the actual transaction value, home buyers have to bear additional risks from such real estate transactions.

Buying a home always need time and effort. Many home buyers can not manage a series of buying steps themselves, so hiring real estate agents to finish the deal quickly and more effectively is a smart decision. If you are still considering whether you should hire an agent or not, the following infographic will show you the benefits of buying a home with an agent:

With her aggressively successful tactics, mega broker Dolly Lenz has sold over $8.5 billion in premium properties to rich and famous customers. Here are some of her valuable secrets for those looking to sell properties.

Business Insider asked real-estate agents across the U.S., and they point out 11 reason that prevent your home from being sold.

Home buyers or sellers normally face many difficulties and obstacles that need time and effort to overcome. To save time, avoid risks and make the purchase faster and smoother, most people hire real estate agents for effective advice and assistance.

Selling home with help from a real estate agent is the ultimate option of many home sellers to promote a fast, smooth sale with a higher price. The following infographic shows the specific benefits you could get when you sell your home with an agent.

One of the most notable changes introduced by Vietnam’s new 2014 property law and its regulations is the revision of the right for overseas Vietnamese, foreign individuals and organizations to own residential houses.

Signs of deceleration of the real estate market have appeared quite clearly in many segments since the beginning of this year, according to Tran Khanh Quang, General Director of Viet An Hoa Real Estate Company.

Regardless of age, all first-time real estate investors are prone to making the same mistakes. Here are some dos and don’ts for new investors.

Tran Khanh Quang, Chairman of the Association for Real Estate Cafe, revealed some secrets of minimizing risks, optimizing profits in real estate investment.

One of the best ways to invest your money and build wealth can be buying property. Many new investors often feel overwhelmed before entering property investment. Here are 4 helpful tips to protect your money poured in property.

The Vietnam’s real estate market has clearly seen signs of a downturn in many segments since the beginning of 2018. So how to gain profit from your realty investment?

Investing in homestay properties has emerged as a new trend in Vietnam. In order to maximize their profit in the long term, investors should take into account a number of factors.

As with other types of investment, real estate investors need a good vision and smart strategies to make it profitable. Here are 6 important guides for investors to avoid loss and gain profit from their real estate investment.

With capital of VND 800 million, instead of gold or securities, real estate is considered an appropriate and feasible investment choice.