A method for simulating the movement behavior of a fluid in a closed moving container is provided. The simulation is based on the determination of the potential movement path of the center of gravity of the volume of the fluid as an elliptical trajectory situated in a disturbance plane having certain semi-axes.

Fluid treatment systems and compositions are provided including (a) at least one material including (1) at least one carboxylic acid functional group and (2) at least one sulfur-containing group selected from the group consisting of sulfonyl functional groups, sulfonate functional groups and mixtures thereof; and (b) at least one friction reducing agent selected from the group consisting of guar gums, polyacrylamides, hydratable cellulosic materials, viscoelastic surfactants, and mixtures thereof. The fluid treatment systems and compositions can be used to treat aqueous systems, for example as fracturing fluids for use in fracturing subterranean formations. Methods for inhibiting formation and/or precipitation of metal oxides in an aqueous composition using the fluid treatment systems or compositions also are provided.

Fluid treatment systems and compositions are provided including (a) at least one material including (1) at least one carboxylic acid functional group and (2) at least one sulfur-containing group selected from the group consisting of sulfonyl functional groups, sulfonate functional groups and mixtures thereof; and (b) at least one scale control agent. The fluid treatment systems and compositions can be used to treat aqueous systems, for example as fracturing fluids for treating aqueous compositions found in subterranean formations. Methods for inhibiting formation and/or precipitation of calcium salts in an aqueous composition using the fluid treatment systems or compositions also are provided.

A pourable aqueous cement composition is disclosed. The cement composition comprises a hydraulic cement, water and a selectively removable material comprising a plurality of selectively corrodible metal powder particles dispersed within the cement or a nanomatrix powder compact, or a combination thereof. An article, including a downhole article, and more particularly a reconfigurable downhole article is disclosed. The article includes a hydraulic cement, wherein the hydraulic cement has at least partially set into a permanent form. The article also includes a selectively removable material dispersed within the cement, the selectively removable material comprising a plurality of selectively corrodible metal powder particles dispersed within the cement or a nanomatrix powder compact, or a combination thereof, wherein the selectively removable material is configured for removal in response to a predetermined wellbore condition.

An apparatus for use in stage-cementing an oil well in the region of a lost-circulation zone that is proximate an annular space defined by the lower end of an outer casing surrounding an inner casing include a load-bearing annular steel plate of substantial thickness that is positioned on, and maintained stationary relative to the inner casing by supporting and retaining means secured to the inner casing, the outer diameter of the plate being less than the inside diameter of the outer casing so that the plate can be lowered with the inner casing string to the desired location inside of the outer casing and, with a layer of gravel, to provide a seal and support the cement poured into the annulus between the inner and outer casings.

In an embodiment, the cement compositions comprise: (i) hydraulic cement, wherein the hydraulic cement has a ratio of CaO to SiO2 in the range of 2.0 to 4.0; and (ii) a water-soluble metaphosphate in a concentration of at least 2.5% bwoc. In another embodiment, the cement compositions comprise: (i) hydraulic cement, wherein the hydraulic cement has a ratio of CaO to SiO2 of less than 2.0; and (ii) a water-soluble metaphosphate; wherein any alkali nitrate is in a concentration of less than 2% bwoc; and wherein any alkali hydroxide, alkali carbonate, or alkali citrate is in a concentration of less than 0.2% bwoc. Methods of cementing in a well comprising forming either of such cement compositions and introducing it into the well are provided.

Systems and methods for managing umbilical lines and one or more jumpers are provided. An example of a system includes a deployment platform carrying a winch and spool assembly, a tether management assembly, and an integrated electrical and/or hydraulic umbilical line extending between a spool on the winch and spool assembly and the tether management assembly. The winch and spool assembly is configured to deploy and to support the umbilical line. The tether management assembly includes a winch and spool assembly for deploying a flying lead and/or annulus jumper adapted to connect to an emergency disconnect package of a well control package for a well. A set of buoyant modules are connected to or integral with a portion of the umbilical line to be used to form an artificial heave compensation loop.

A centralizer comprises a first body portion, a second body portion, a plurality of bow springs connecting the first body portion to the second body portion, and one or more expandable elements coupled to the first body portion and the second body portion. A method of centralizing a wellbore tubular comprises compressing a bow spring radially inward from a starting position to a compressed position, wherein the bow spring is coupled to a first body portion and a second body portion, applying a tensile force between the first body portion and the second body portion while the bow spring is in the compressed position, and restoring the bow spring from the compressed position to the starting position.

When conducting cementing operations within confined locales, such as the annular space within a wellbore, it can sometimes be difficult to successfully deliver an uncured cement composition to a desired location. Cementing methods can comprise: providing a cement composition comprising a cement and a property control package, the property control package comprising: a filtration control agent; a friction reducer; and a setting accelerator; introducing the cement composition into a mineral exploration wellbore; and setting the cement composition in the wellbore.

A tank or bed has a plurality of sidewalls that create a bed cavity and a Fresnel panel frame that includes at least one Fresnel panel. The Fresnel panel frame may be adjacent to the bed cavity and may cover at least a portion of the bed cavity. An amount of sludge may be contained within the bed cavity. When placed in sunlight, the heat enhanced by the Fresnel panels may heat the sludge sufficiently for the sludge to be used as fertilizer.

A device for compensating deviations from a coaxial arrangement of components of a regulating organ, said regulating arrangement being comprised of a regulating organ, a crown pipe, and an immersion cup which serve for controlling the gas pressure of a coke oven chamber, with the regulating arrangement being comprised of an immersion cup with a water immersion that seals the gas space of a coke oven chamber versus the gas collecting main and/or plant units downstream, and wherein the height of the water level of the water immersion represents a regulating means to control the gas pressure, and wherein said regulating arrangement is furthermore comprised of an immersion pipe that configures a specially shaped crown pipe at its end submerging into the water of the immersion cup, and that is comprised of a regulating organ to regulate the water level.

A method for creating laboratory-scale reactive distillation apparatus from provided modular components is described. At least two types of modular distillation column stages are provided. A first type of modular stage comprises two physical interfaces for connection with a respective physical interface of another modular stage. A second type modular stage comprises one such physical interface. At least one type of tray is provided for insertion into the first type of modular stage. A clamping arrangement is provided for joining together two modular stages at their respective physical interfaces for connection to form a joint. The invention provides for at least three modular stages can be joined. At least one sensor or sensor array can be inserted into each modular stage. At least one controllable element can be inserted into each modular stage. The invention provides for study of traditional, advanced, and photochemical types of reactive distillation.

A method of operating an evaporator is described. In evaporator feed water, a Taylor bubble is developed which has an outer surface including a thin film in contact with an inner surface of an outer wall of an evaporator tube. The Taylor bubble is heated as it rises within the evaporator tube so that liquid in the thin film transitions into vapor within the bubble.

Disclosed herein is a system comprising an evaporation unit comprising a first heat exchanger in fluid communication with a second heat exchanger; where the first heat exchanger is operative to heat an effluent stream comprising an amine solvent and/or amine byproducts and water and to discharge the effluent stream to the second heat exchanger; where the second heat exchanger is operative to convert the effluent stream into a distillate stream and a concentrate stream; and a reverse osmosis unit in fluid communication with the evaporation unit; where the reverse osmosis unit comprises a first reverse osmosis unit that is operative to receive the distillate stream and to separate water from byproducts of the amine solvent such that the water has a purity of greater than 95%, based on the weight of the distillate stream.

The invention relates to a fixing element for locking a hinged hand crank on the input shaft of a support winch for semi-trailers, wherein the hand crank is fastened to the input shaft in an articulated manner and can pivot between at least one folded-in rest position and at least one folded-out usage position. According to the invention, said fixing element has a fastening section for fastening to the hand crank and a spring bar connected to the fastening section on which at least one locking section is formed, wherein the locking section reaches over the end face of the input shaft in a form-fitting manner in a folded-out usage position of the hand crank and is simultaneously pulled against said end face of the input shaft.

Diverting pulley arrangement of an elevator, which includes an axle, at least one diverting pulley that rotates while supported on the axle, a faceplate structure, in relation to which and supported by which the diverting pulley is arranged to rotate on the first side of the faceplate structure, which axle is locked so that it does not rotate in relation to the faceplate structure by the aid of a locking element, which locking element is on the second side of the faceplate structure and supported so that it does not move in relation to the faceplate structure. The locking element is placed against the locking surface included in the axle so that the contact point of the locking element and the locking surface of the axle is at least partly visible.

A three dimensional wire flying system includes a plurality of winches collectively hanging an object and a control unit for controlling the plurality of winches and the main safety device. Each of the plurality of winches includes a drum unit, a wire wound on the drum unit, a motor unit which provides power to the drum unit, a brake module which stops rotation of the drum unit, a limit switch which operates upon detecting a hardware limit state, and a servo-system. Each of the plurality of winches operates to move the object in a three dimensional space in three directions, including an up-down direction, a left-right direction and a forward-backward direction, and each winch provides a multi-level safety protection.

A hydraulic jack attachment for quickly and safely jacking up high clearance objects in an efficient manner. The hydraulic jack attachment generally includes a base support adapted to be positioned underneath an object to be lifted. The base support includes a footing which includes one or more wheels to aid in repositioning the base support. A linkage tube is interlocked with a lifting member and positioned within the base support. A hydraulic jack may be placed into a lower end of the base support via an access opening. When the hydraulic jack is lifted, it will force the linkage tube and lifting tube upwards. A lifting head positioned on the upper end of the lifting tube will press against and force the object upwardly to jack the object up.

The invention provides a composition for topical treatment of hair loss/alopecia including three natural, active ingredients, caffeine, saw palmetto berry extract, and epigallocatechin-3-gallate (EGCG). The invention also provides methods for using this composition to treat hair loss.

The invention relates to a cosmetics applicator having a handle section, an applicator element and a shaft section connecting the applicator element and the handle section, wherein the applicator element includes a core element of a first material and a bristle element which at least partially envelops the core element and includes a second material preferably different from the first material with regard to its hardness and/or flexibility.

The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.

Additives may be used to lower the set up point for bitumen thereby allowing it to be transported from place to place more easily. Additives useful for lowering the set up point of bitumen include alkylphenol formaldehyde resins and oxyalkylated alkylphenol formaldehyde resins; amines and esters; solvents; and combinations thereof.

An object is to overcome the drawbacks of conventional blue phthalocyanine pigments upon the formation of images, and to develop a blue pigment that can satisfactorily exhibit a greenish blue color high in chroma and excellent in colorfulness, brightness, dispersibility, hue, tinting power and the like and that is applicable to various image recording methods. The object can be achieved by a greenish blue pigment, which exhibits a greenish blue hue of high chroma and contains a pigment represented by the following formula (I): wherein the number, m, of substituent phthalimidomethyl group(s) is in a range of 1.0≦m≦5.0, and the number, n, of a substituent sulfonic group R1 is in a range of 0.05≦n≦1.0.

The present invention relates to a novel cement which makes possible the preparation of concrete, grout or mortar which is resistant to internal sulfate reactions and to external sulfate attacks, and also the use of this cement for the preparation of concrete, grout or mortar.

The invention relates to CO2 capturing binder with an amortized environmental cost, the method of manufacture thereof by means of selecting, purifying and optimizing the carbide lime paste for use as a cementing material, and aggregates for the manufacture of lime paints and slurries, stuccos, mortars and concretes having multiple applications in the construction industry, in architectural restoration, in public works and land conditioning, object of the present invention. It is basically characterized in that the raw material is the residue in the form of sludge generated in the industrial manufacture of acetylene (C2H2) from calcium carbide (CaC2) the fundamental component of which is calcium hydroxide (Ca(OH)2) in highly reactive nanometric formations treated in a specific manner according to the invention.

The method includes subjecting the pozzolans in crushed state to a high energetic mechanical processing by grinding in a grinding equipment, whereby the pozzolan particles receive mechanical impulses, and the grinding is carried out for a predetermined time resulting in a compressive strength of a 2 inch side cube of mortar having 80% Portland cement and 20% natural pozzolan in a ratio of 1:2.75 to standard sand and in addition water required to obtain a flow of the mortar according to American standard ASTM C 109, which has been properly compacted under vibration and hardened at +20° C. in sealed condition, which after 28 days is ≧75% of the compressive strength of a 2 inch side cube, treated as the cube, of a mortar having a ratio of Portland cement:sand of 1:2.75 and water corresponding to 48.5% of the weight of Portland cement.

A surface treatment composition for inkjet media includes: at least one surface sizing agent selected from the group consisting of starch, starch derivatives, polymeric materials, and combinations thereof; and an ink fixative selected from the group consisting of at least one high valence metallic salt, at least one high valence complex poly-salt, and combinations thereof. The ink fixative is present in the surface treatment composition from about 10 weight% to about 50 weight% of the surface treatment composition. The at least one high valence metallic salt and the at least one high valence complex poly-salt have a valence greater than divalent. Additionally included are a method of making and a system for printing the surface treated media; and an inkjet printable paper.

A raw batch composition for concrete or concrete wherein the raw batch composition comprises Portland cement of about 15 wgt. % to about 45 wgt. % and dune sand preferably red dune sand is present in an amount of about 40 wgt. %. The dune sand has a particle size of less than or equal to 45 microns. The composition also includes limestone powder ranging from about 15 wgt. % to 45 wgt. % with particle sizes less than or equal to 45 microns to form a base material. To this base material suitable amounts of fine aggregate, coarse aggregate, water and superplasticizer are added. A method for producing a cast concrete product having a compressive strength of between 62 MPa and 90 MPa is disclosed. The method comprises a step of providing Portland cement, dune sand and limestone powder.

The present invention relates to the production of ternesite clinkers containing 20 to 100% by weight C5S2$ and less than 15% by weight C4A3$, and to the use of ternesite as an additive to Portland cement or Portland composite cement, and to a binder containing 20 to 95% by weight Portland cement (clinker) and 80 to 5% by weight ternesite (clinker).

Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or Monetite-forming calcium phosphate powder composition. In another embodiment, the powder composition comprises porous β-tricalcium phosphate (β-TCP) granules and at least one additional calcium phosphate powder. In another embodiment, the powder composition comprises calcium silicate powder. In a further embodiment, the powder composition comprises calcium aluminate powder. In another embodiment, the powder composition is a cement composition and comprises nanopowders having a grain size of less than 1 micron. Hardened cements are formed from such hydraulic cement compositions, and methods of producing hardened cements, kits, and articles of manufacture employ such hydraulic cement compositions.

An end treatment portion 1a which treats ends Wa and Wb of an electric wire W and a transfer portion 7 which transfers the electric wire W are provided; a discharge portion 6, which discharges the electric wire W which is subjected to an end treatment by the end treatment portion 1a and transferred by the transfer portion 7, is also provided; the discharge portion 6 includes a discharge beam 11 for securing the electric wire W in a predetermined arrangement pattern; a calculation portion 20, which controls a securing treatment for securing the electric wire W to the discharge beam 11 in the discharge portion 6, is provided; and the predetermined arrangement pattern is set by the calculation portion 20 based on a content of processing the electric wire W at a subsequent process.

The present invention relates to a steel net reinforcement structure which is used for a conveyer belt or a shutter screen. The steel net reinforcement structure comprises: a steel net including hooks projecting from both sides thereof; a reinforcement including a slit cut open along a diagonal direction on both sides thereof; and a steel core which can lock the hooks which are inserted on both inner sides of the reinforcement. The steel net reinforcement structure can be wound conveniently and flexibly while reinforcing strength of the steel net.

A machine for forming a two-stage wire tie around a pair of bars to bind the bars together. The machine comprises an arrangement for passing the wire in a loop around the bars and a twisting head for twisting the ends of the loop together. The twisting head comprises an arrangement for gripping the ends of the wire and a tie plate through which the ends of the wire pass, and the head is resiliently mounted relative to the bars so as to allow the tie plate to move through a predetermined amount of travel towards the bars, to thereby define the length of a first stage of the tie. The machine is adapted thereafter to release the ends of the wire and continue twisting these to form a second stage of the tie.

A wire loading magazine for a twist attachment device includes a magazine assembly adapted to carry a supply of attachment wire segments and a wire loading assembly carried by the magazine assembly and adapted to individually and sequentially load the attachment wire segments from the magazine assembly into the twist attachment device.

Apparatus and methods for filament crimping. In one embodiment, the apparatus comprises a body and a filament crimp element. The filament crimp element comprises a first set of cavities disposed at a spacing which creates a first set of features and a second set of cavities disposed at a spacing which creates a second set of features. The first and second set cavities are substantially opposite one another. The first set of features are adapted to be placed at least partially within the second set of cavities and the second set of features are adapted to be placed at least partially within the first set of cavities. Methods and apparatus for the manufacture of the device are also disclosed. In addition, methods for automated placement and manufacture of assemblies using the crimp elements are also disclosed.

A pipe handling apparatus has a frame, a boom pivotally connected to the frame so as to be movable between a first position and a second position, an arm extending outwardly of the boom when the boom is in the second position, a gripper affixed to the end of the arm opposite the boom, a first line having a first end affixed to the boom, a second line interconnected to an opposite end of the first line and connected to the frame, and an actuator interconnected to the first and second lines. The actuator changes an angular relationship of the first and second lines so as to selectively tension the lines. The second line includes a first cable offset from linear alignment with the first line and a second cable extending in angular relationship with the first cable.

A method for controlling a hoisting or lowering movement of a load, which is suspended from a hoisting mechanism of a crane by means of at least two hoisting cables trained round cable sheaves on the load, by monitoring the position of the load and braking and/or stopping the hoisting mechanism upon detection of an undesirable position, wherein the cable sheaves are each connected to the load for pivoting about a horizontal axis, and the position of the load is monitored by detecting a pivoting movement of at least one of the cable sheaves.

A movement system includes a bridge crane, a trolley, and a movement device. The movement device includes an attachment portion, a plurality of housings, first and second curved elements, a cable, and a cable angle sensor. The curved elements are pivotally attached to housings and perpendicularly overlap with one another such that a first slot defined in the first curved element is perpendicular to a second slot defined in the second curved element. The first curved element is pivotable about a first axis and the second curved element is configured to pivot about a second axis. The cable extends from the attachment portion and through each of the slots. The cable is pivotable to angularly displace at least one of the curved elements about a respective axis. The cable angle sensor is configured to measure the angular displacement of the at least one of the first and second curved elements.

A system and method are disclosed for containing an underwater gas or oil leak. The system and method may include a vortex device comprising a vortex chamber, a high pressure inlet tangentially engaging the vortex chamber, a low pressure inlet axially engaging the vortex chamber, and a low pressure outlet axially engaging the vortex chamber opposite the low pressure inlet. The vortex device may be positioned underwater proximate an underwater leak. A vortex may be generated within the vortex device. The vortex device may then collect a leak flow issuing from the underwater leak. The vortex device may collect the leak flow via the low pressure inlet, the high pressure inlet, or both.

A system and method determine when fluid is not flowing properly from a secondary infusion source during a secondary infusion. The system includes an upstream pressure sensor and a processor programmed to receive signals from the sensor and analyze the signals to determine if secondary fluid flow is proper. The processor samples the output signals from the upstream pressure sensor and analyzes the sampled signals to determine if a pressure rise in the infusion line has occurred when the secondary infusion is initiated. If a pressure rise, indicating that fluid from the secondary container has begun flowing into the infusion line, has not been detected, the processor is programmed to provide a signal indicating that attention should be given to the infusion set up.

A medical balloon with a variable diameter that is reinforced with continuous fibers woven to form a fabric with a varying number of layers and fiber densities. Portions of the balloon having a relatively smaller diameter are reinforced with a fabric having a reduced fiber density and an increased number of layers to facilitate the placement of the layers. The fabric also includes a braiding pattern that facilitates the transition from a single layer fabric to a multiple layer fabric. Also described is a manufacturing method for the braiding and layering.

This invention provides new above knee (AK) and below the knee (BK) prosthetic sockets and implements specific manufacturing processes for the production of prosthetic sockets through the automated, computer controlled bi-axial and tri-axial braiding of sockets, over a mold or mandrel made of carved foam, plaster material or wax that is a replica of the patient's truncated limb, and is created by a Computer Aided Design (CAD) file controlling a Numerically Controlled (CNC) machine tool. This method of manufacture using aerospace fibers such as graphite or Kevlar, and high performance resins, is used to create a socket which is stronger and lighter weight than conventionally manufactured sockets. Braiding also allows incorporation of woven cloth, tapes and other reinforcements into the braiding process for added strength at selected areas. The method dramatically decreases the production time and cost of the prosthetic relative to conventional methods.

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Method and instrumentation for detection of rail defects, in particular rail top defects, in a railway-track by measuring an axle box acceleration signal of a rail vehicle, wherein a longitudinal axle box acceleration signal is used as a measure to detect the occurrence of said rail defects. The method also includes measuring a vertical axle box acceleration signal of said rail vehicle, whereby the longitudinal axle box acceleration signal is used in combination and simultaneously with said vertical axle box acceleration signal. It is preferred that the longitudinal axle box acceleration signal is used to remove from said vertical axle box acceleration signal a signal-part that relates to vibrations of the rail vehicle's wheel set, including the bearing and axle box, and that the axle box acceleration signals are filtered for removing signal-parts contributed by vibrations of the track, including the rail, rail pads, fasteners, sleepers, and ballast.

Data representative of a train consist (the train consist comprising a plurality of locomotives and a plurality of cars) and data representative of a route for the train consist can be processed by a processor to automatically determine which locomotives in the train consist should be powered on and which locomotives in the train consist should be shut down for each segment of the route. The processor can make these determinations based on an analysis of the train consist data and the route data with respect to a plurality of considerations that affect train efficiency. Recommendations for locomotive startups and shutdowns in accordance with such automated determinations can then be presented to the train crew for the crew to use during train operations. It is believed that when train crews are in compliance with such recommendations, significant improvements in efficiency, particularly with respect to fuel consumption, can be achieved.

A method for calibrating a moving object impact detector is disclosed. A controller may receive input indicative of movement of an impact element from a first position to a second position. The controller may also receive an activation signal corresponding to the movement of the impact element. The controller may further receive input indicative of instructions to correlate the activation signal with the movement of the impact element. The controller may selectively set the activation signal as a reference signal for the detector, with the reference signal being indicative of an impact the moving object impact detector is set to detect.

Considerable damage to rails, wheels, and trucks can result from geometric anomalies in the wheelsets, rails, and truck hardware. A solution for identifying and quantifying geometric anomalies known to influence the service life of the rolling stock or the ride comfort for the case of passenger service is described. The solution comprises an optical system, which can be configured to accurately perform measurements at mainline speeds (e.g., greater than 100 mph). The optical system includes laser line projectors and imaging cameras and can utilize structured light triangulation.

A method designed to replace a compromised instrument case with a new case without the need to disconnect any wire, relay or any other electric equipment is described herein. The instrument panel is supported for example by a temporary support frame during the dismantling of the old case and the assembly of the new case. The new case is therefore assembled on site around the instrument panel. The new instrument case includes a floor which is made of at least two parts, one on each side of the wiring. The instrument case therefore remains in a normal working mode during the entire replacement procedure thus preventing downtime. As well, the amount of manpower required for the replacement of an instrument case is drastically reduced.

Compounds of Formula I, including pharmaceutically acceptable salts, as well as compositions containing these compounds, have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV: