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[ASAP] Development of a General Automated Flow Photoredox <sup>18</sup>F-Difluoromethylation of N-Heteroaromatics in an AllinOne Synthesizer

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00442




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[ASAP] What Elements Contribute to a High-Quality Continuous Processing Submission for <italic toggle="yes">OPR&D</italic>?

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00020




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[ASAP] Development of an Efficient Synthetic Process for Broflanilide

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00028




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[ASAP] Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00427




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[ASAP] Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00087




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[ASAP] Development and Production of an Enantioselective Tetrahydroisoquinoline Synthesis Enabled by Continuous Cryogenic Lithium–Halogen Exchange

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00141




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[ASAP] <sc>d</sc>-Serine as a Key Building Block: Enzymatic Process Development and Smart Applications within the Cascade Enzymatic Concept

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00024




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[ASAP] Catalyst-Free Cyclization- and Curtius Rearrangement-Induced Functional Group Transformation: An Improved Synthetic Strategy of First-in-Class ATX Inhibitor Ziritaxestat (GLPG-1690)

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00511




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Development of an engineered thermostable amine dehydrogenase for the synthesis of structurally diverse chiral amines

Catal. Sci. Technol., 2020, 10,2353-2358
DOI: 10.1039/D0CY00071J, Paper
Lei Liu, Dong-Hao Wang, Fei-Fei Chen, Zhi-Jun Zhang, Qi Chen, Jian-He Xu, Zhi-Long Wang, Gao-Wei Zheng
Structurally diverse chiral amines and amino alcohols were synthesized using an engineered thermostable amine dehydrogenase, demonstrating its extensive synthesis potential.
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Trace amounts of Cu(OAc)2 boost the efficiency of cumene oxidation catalyzed by carbon nanotubes washed with HCl

Catal. Sci. Technol., 2020, 10,2523-2530
DOI: 10.1039/C9CY02536G, Paper
Jie Deng, Yuhang Li, Yonghai Cao, Hongjuan Wang, Hao Yu, Qiao Zhang, Jiangliang Zuo, Feng Peng
Trace amounts of Cu(OAc)2 significantly improve the activity and selectivity of cumene oxidation catalyzed by HCl-washed carbon nanotubes.
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Development of BiOI as an effective photocatalyst for oxygen evolution reaction under simulated solar irradiation

Catal. Sci. Technol., 2020, Advance Article
DOI: 10.1039/D0CY00266F, Paper
Tzu-Hsin Chen, Masaaki Yoshida, Shun Tsunekawa, Jia-Hao Wu, Kun-Yi Andrew Lin, Chechia Hu
In this study, crystalline BiOI powders were prepared for photocatalytic O2 evolution in the presence of NaIO3 as the electron mediator.
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Homogeneous vs. Heterogeneous: Mechanistic Insights into Iron Group Metal-Catalyzed Reductions from Poisoning Experiments

Catal. Sci. Technol., 2020, Accepted Manuscript
DOI: 10.1039/D0CY00644K, Minireview
Axel Jacobi von Wangelin, Sebastian Sandl, Dominik Gärtner
Iron group metal catalysts constitute a promising alternative to well-established noble metal catalysts in reduction reactions. However, the development of effective 3d metal catalysts has largely been hampered by their...
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Photocatalytic degradation of tetracycline hydrochloride over rugby-like β-Ga2O3 with a 3D hierarchically assembled porous structure for environmental remediation

Catal. Sci. Technol., 2020, Advance Article
DOI: 10.1039/D0CY00562B, Paper
Lingxing Zeng, Jiaqi Wang, Qingrong Qian, Qinghua Chen, Xin-Ping Liu, Yongjin Luo, Hun Xue, Zhaohui Li
A novel rugby ball-like β-Ga2O3 photocatalyst with a 3D hierarchically assembled porous structure was constructed via a facile precipitation–calcination method. The as-synthesized Ga2O3 exhibits a high photocatalytic efficiency compared to commercial Ga2O3 and Degussa P25.
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men

Extend ::before background in fixed element

Hi!

Does anyone have any idea how I can make the background gradient to continue when scrolling?

Code: https://jsfiddle.net/Lfpb8woa/1/

Thanks in advance!




men

Reliance General Insurance scraps IPO plan; withdraws draft offer documents

Markets regulator Sebi had received draft red herring prospectus for the proposed IPO on February 8




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SBI Cards and Payment Services' $1.25 billion-IPO to open on March 2

The company plans to issue new shares worth Rs 500 crore and will offer up to 130.5 million shares for sale




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SBI Cards & Payment IPO price band fixed at Rs 750-755, opens on March 2

The second largest card issuer SBI Cards & Payment Services, which is hitting the primary market with a Rs 9,000-crore initial public offering, has set the price band for the share sale at Rs 750-755. The IPO, opening on March 2 and closing on 4, comprises fresh issue of equity shares aggregating to Rs 500 crore and an offer for sale where promoters will offload nearly 13 crore shares. Promoters SBI and Carlyle Group will offload 3.73 crore shares and 9.32 shares respectively. SBI holds 74 per cent in SBI Card and the rest by the Carlyle Group and they will pare their stakes by 4 per cent and 10 per cent respectively, SBI Managing Director Dinesh Khara told reporters kicking of the IPO roadshow. SBI Card's market share in terms of the number of credit cards outstanding is 18 per cent. The pure-play credit card company's gross NPA stood at 2.47 per cent in December 2019 compared to 2.44 per cent in March 2019 and 2.83 per cent in March 2018, he said. SBI Card managing director and




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SBI Cards IPO: Allotment of shares finalised, steps to check status

The SBI Cards IPO is one of the largest share sale in recent times, both in terms of size and oversubscription




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New containment zones come up in south Kolkata

Several south Kolkata neighbourhoods, which had managed to stave off coronavirus for the past 40 days, are now on the city’s containment-zone map with fresh cases being reported from them. The affected portions include added areas — both sides of the Tolly canal, EM Bypass and Behala — and some upscale south Kolkata locations, like Lord Sinha Road and Hindustan Park.




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Women's manga in Asia and beyond: uniting different cultures and identities / Fusami Ogi, Rebecca Suter, Kazumi Nagaike, John A. Lent, editors

Rotch Library - PN6714.W664 2019




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An acoustic/thermo-responsive hybrid system for advanced doxorubicin delivery in tumor treatment

Biomater. Sci., 2020, 8,2202-2211
DOI: 10.1039/C9BM01794A, Paper
Li Zhang, Shiyu Zhang, Huajian Chen, Yu Liang, Bingxia Zhao, Wanxian Luo, Qian Xiao, Jinheng Li, Junqiao Zhu, Chao Peng, Yaru Zhang, Zhe Hong, Ying Wang, Yingjia Li
Ultrasound-assisted fast extravasation and the following laser-triggered drug release of thermo-sensitive liposomes synergistically enhanced drug delivery in deep tumors.
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Stabilization of indocyanine green dye in polymeric micelles for NIR-II fluorescence imaging and cancer treatment

Biomater. Sci., 2020, 8,2245-2254
DOI: 10.1039/C9BM02010A, Paper
Gil Yeroslavsky, Masakazu Umezawa, Kyohei Okubo, Karina Nigoghossian, Doan Thi Kim Dung, Keiji Miyata, Masao Kamimura, Kohei Soga
Encapsulation of ICG and IR-1061 in PCL–PEG micelles producing agents with increased stability of ICG and tunable PTT and PDT activity. The micelles are also useful for NIR imaging and NIR nanothermometry.
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Matrix stiffness-regulated cellular functions under different dimensionalities

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01809C, Review Article
Jiajun Zhong, Yuexiong Yang, Liqiong Liao, Chao Zhang
The microenvironments that cells encounter with in vitro.
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Development of new self-assembled cationic amino liposomes for efficient gene delivery

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00331J, Communication
Yihang Wu, Yue Xiong, Ling Wang, Quanming Zhou, Linxian Li, Pavel A. Levkin, Gary Davidson, Liqian Gao, Wenbin Deng
A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.
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Fixed-point “blasting” triggered by second near-infrared window light for augmented interventional photothermal therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00372G, Paper
Yongbin Cao, Boshu Ouyang, Xiaowei Yang, Qin Jiang, Lin Yu, Shun Shen, Jiandong Ding, Wuli Yang
Tumors were effectively destroyed by a mild photothermal effect and the subsequent gas mechanical damage triggered by NIR-II light.
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Protein cages and virus-like particles: from fundamental insight to biomimetic therapeutics

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00159G, Minireview
Nicole F. Steinmetz, Sierin Lim, Frank Sainsbury
Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
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Photothermal augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00549E, Paper
Tianhong Teng, Ronggui Lin, Ziguo Lin, Kun Ke, Xianchao Lin, Maoen Pan, Da Zhang, Heguang Huang
Preparation of Abraxane@MoSe2 and its PTT effect augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode.
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Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration

Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper
Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
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Bioinspired inorganic nanoparticles and vascular factor microenvironment directed neo-bone formation

Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper
Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
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Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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A medical adhesive used in a wet environment by blending tannic acid and silk fibroin

Biomater. Sci., 2020, 8,2694-2701
DOI: 10.1039/D0BM00322K, Paper
Xijie Gao, Qiyuan Dai, Longtao Yao, Hua Dong, Qingtao Li, Xiaodong Cao
A medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.
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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
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Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489

Toxicol. Res., 2019, 8,1057-1058
DOI: 10.1039/C9TX00158A, Comment
Michael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. Holstege
We point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.
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Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands

Toxicol. Res., 2019, 8,885-895
DOI: 10.1039/C9TX00149B, Paper
Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela Casini
Novel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.
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Environmental distribution of the neurotoxin L-BMAA in Paenibacillus species

Toxicol. Res., 2019, 8,781-783
DOI: 10.1039/C9TX00203K, Viewpoint
Peter B. Nunn, Geoffrey A. Codd
The neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.
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Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
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Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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men

Central Board of Direct Taxes amends Rule 44G of Income-tax Rules 1962

It also states that if a resolution is arrived, the same shall be communicated to the assessee, who shall communicate his acceptance or non-acceptance within 30 days




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Tamil Nadu CM asks PM to keep Electricity Amendment Bill on hold till talks

Proposed Bill takes away certain powers of the State government, and seeks to bring in changes in the existing Electricity Act that would make power utilities in the public sector totally unviable




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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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Proton exchange membrane with plasmon-active surface for enhancement of fuel cell effectivity

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00295J, Paper
Roman Elashnikov, Kristina Zahorjanova, Elena Miliutina, Zdenka Kolska, Miroslav Cieslar, Václav Švorčík, Oleksiy Lyutakov
The action of fuel cells with proton-exchanged membrane (PEM) requires the implementation of hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR) on the opposite sides of PEM. Recently, based...
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A three-dimensional Cu nanobelt cathode for highly efficient electrocatalytic nitrate reduction

Nanoscale, 2020, 12,9385-9391
DOI: 10.1039/C9NR10743F, Paper
Xiaodan Wang, Mengqi Zhu, Guoshen Zeng, Xun Liu, Chihhsiang Fang, Chuanhao Li
A three-dimensional Cu nanobelt cathode was developed to efficiently catalyze the electrocatalytic nitrate reduction process.
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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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Analysis of sparse molecular distributions in fibrous arrangements based on the distance to the first neighbor in single molecule localization microscopy

Nanoscale, 2020, 12,9495-9506
DOI: 10.1039/C9NR10805J, Paper
Alan M. Szalai, Lucía F. Lopez, Miguel Ángel Morales-Vásquez, Fernando D. Stefani, Pedro F. Aramendía
We introduce a robust and sensitive metric to characterize the underlying structure responsible for the molecular distribution, even at a very low labeling density.
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A solution-processed zero-dimensional all-inorganic perovskite scintillator for high resolution gamma-ray spectroscopy detection

Nanoscale, 2020, 12,9727-9732
DOI: 10.1039/D0NR00772B, Paper
Qiang Xu, Juan Wang, Wenyi Shao, Xiao Ouyang, Xiang Wang, Xinlei Zhang, Yong Guo, Xiaoping Ouyang
A zero-dimensional all-inorganic CsPbBr3 nanocrystal embedded Cs4PbBr6 scintillator has been achieved. Owing to the low dimensional quantum effect, this all-inorganic scintillator exhibits desirable scintillation performance.
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Reply to the ‘Comment on “Hierarchically porous, ultra-strong reduced graphene oxide–cellulose nanocrystal sponges for exceptional adsorption of water contaminants”’ by J. Ma, Y. Xiong and F. Yu, Nanoscale, 2019, 11, DOI: 10.1039/C8NR08780F

Nanoscale, 2020, 12,9899-9901
DOI: 10.1039/D0NR01846E, Comment
Nariman Yousefi, Nathalie Tufenkji
We respond to the comments of Ma et al. and clarify the rationale behind our methodology and why it is suitable for our work.
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Modulated podosome patterning in osteoclasts by fullerenol nanoparticles disturbs the bone resorption for osteoporosis treatment

Nanoscale, 2020, 12,9359-9365
DOI: 10.1039/D0NR01625J, Communication
Kui Chen, Huan Geng, Wei Liang, Haojun Liang, Yujiao Wang, Jianglong Kong, Jiaxin Zhang, Yuelan Liang, Ziteng Chen, Jiacheng Li, Ya-nan Chang, Juan Li, Gengyan Xing, Gengmei Xing
Fullerenol hampers podosome patterning in osteoclasts, results in the failure of bone resorption.
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Point defect induced intervalley scattering for the enhancement of interlayer electron transport in bilayer MoS2 homojunctions

Nanoscale, 2020, 12,9859-9865
DOI: 10.1039/D0NR01339K, Paper
Yang Ou, Zhuo Kang, Qingliang Liao, Shihan Gao, Zheng Zhang, Yue Zhang
The interlayer transport of MoS2 homojunctions can be enhanced by point defect induced K–Q intervalley scattering.
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Nanosphere-shaped ammonio methacrylate copolymers: converting a pharmaceutical inactive ingredient to efficient therapeutics for experimental colitis

Nanoscale, 2020, 12,9590-9602
DOI: 10.1039/D0NR00465K, Paper
Brice Moulari, Maryam A. Shetab Boushehri, Jean-Paul Pais de Barros, Thilo Faber, Arnaud Béduneau, Laurent Lagrost, Yann Pellequer, Alf Lamprecht
Even in the absence of any drug load, nanosphere-shaped ammonio methacrylate copolymers can mitigate murine experimental colitis.
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