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Coronavirus chokes the drug trade — from Wuhan, through Mexico and onto U.S. streets

The coronavirus pandemic has disrupted many industries, both legal and illicit. Production of fentanyl, which relies on chemical ingredients sourced mainly from Wuhan, China, has been particularly hard hit.




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'Breakthrough' COVID-19 Tests Are Currently Cheap, Fast--and Not Very Accurate

Antigen-based assays could be used in the home, but critics say their error rates are still an issue

-- Read more on ScientificAmerican.com




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Former Bank of China Managers and Their Wives Sentenced for Stealing More Than $485 Million, Laundering Money Through Las Vegas Casinos

Two former managers of the Bank of China and their wives were sentenced today after their convictions on Aug. 29, 2008, by a federal jury in Las Vegas on charges of racketeering, money laundering, international transportation of stolen property as well as passport and visa fraud.



  • OPA Press Releases

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Novo Nordisk Agrees to Pay $9 Million Fine in Connection with Payment of $1.4 Million in Kickbacks Through the United Nations Oil-for-food Program

Novo Nordisk A/S (Novo), a Danish corporation based in Bagsvaerd, Denmark, has agreed to pay a $9 million penalty for illegal kickbacks paid to the former Iraqi government.



  • OPA Press Releases

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Virginia Man Sentenced to 41 Months in Prison for Selling Counterfeit Software Through the Internet

Gregory William Fair, 46, of Falls Church, Va., was sentenced today to 41 months in prison for selling counterfeit computer software on the Internet, in violation of criminal copyright infringement laws.



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Ohio Attorney Charged with Tax Fraud, Obstruction of Justice for Scheme to Hide Income and Assets Through Trusts and in Foreign Bank Account

Aristotle R. Matsa, an attorney in Columbus, Ohio, was charged with tax offenses, obstruction of justice and additional charges in a 20-count indictment unsealed today.



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Oregon Man Charged with Operating Illegal Money Transmitting Business That Moved More Than $172 Million Through Shell Corporations in the United States

Victor Kaganov, who emigrated from Russia and set up numerous shell corporations in Oregon on behalf of Russian clients, was arrested today on charges of operating an unlicensed money transmitting business.



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Oregon Man Pleads Guilty to Operating Illegal Money Transmitting Business That Moved More Than $172 Million Through Shell Corporations in the United States

Victor Kaganov, who emigrated from Russia and set up numerous shell corporations in Oregon on behalf of Russian clients, pleaded guilty today to charges of operating an unlicensed money transmitting business.



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Former and Current Soldiers and Recruiter Indicted for Allegedly Obtaining Recruiting Bonuses Through Fraud Scheme

Six current and former members of the U.S. military have been charged a 41-count indictment in San Antonio for allegedly defrauding various U.S. military components and their contractor of approximately $127,000 by fraudulently obtaining recruiting bonuses.



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Remarks as Prepared for Delivery by Attorney General Eric Holder at the “Progress Through Prosperity” Dinner with President Leonel Fernandez

"It is in this spirit of friendship that I have traveled to your beautiful country. And I am grateful, on a very personal level, for this opportunity to help build upon the progress that our nations – and America’s allies throughout the Caribbean region – have made together over the years," said Attorney General Holder.




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Department of Justice and Partner Agencies Announce Neighborhoods to Receive Innovative Support Through the Building Neighborhood Capacity Program

The Department of Justice’s Bureau of Justice Assistance, on behalf of the White House Neighborhood Revitalization Initiative, today announced the eight neighborhoods that will receive training and technical assistance through the groundbreaking Building Neighborhood Capacity Program.



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Acting Associate Attorney General Tony West Speak at Faith and Neighborhoods in Action: A Symposium to Address Economic Recovery Through Strong Communities and Job Creation

"Through the Strong Cities, Strong Communities Initiative, the White House is leading a federal effort to spark economic growth in five cities and one region, helping them to maximize resources and leverage partnerships with businesses, philanthropies, and non-profit organizations," said Acting Associate Attorney General West.




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International Competition Network Advances Convergence Through Initiatives on Enforcement Cooperation and Investigative Process

The International Competition Network advanced convergence through important initiatives on international enforcement cooperation and investigative processes in competition cases.



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Rockville, Md., Property Purchased with Nigerian Corruption Proceeds Forfeited Through Justice Department’s Kleptocracy Initiative

A forfeiture judgment was executed today against real property with an estimated value of more than $700,000 in Rockville, Md., that had been purchased with corruption proceeds traceable to Diepreye Solomon Peter Alamieyeseigha, a former Governor of Bayelsa State, Nigeria.



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Two Charged with Leading a Conspiracy to Defraud and Extort Spanish-Speaking Consumers Through Fraudulent Call Centers

A grand jury in Miami, Florida, indicted two individuals and two corporations for allegedly operating call centers in Peru that lied to and threatened Spanish-speaking victims into paying fraudulent settlements.



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Two North Carolina Residents Plead Guilty to Defrauding Elderly Through Offshore Sweepstakes Scheme

A North Carolina couple pleaded guilty for leading a Costa Rican sweepstakes fraud scheme that defrauded hundreds of elderly Americans



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U.S. Forfeits Over $480 Million Stolen by Former Nigerian Dictator in Largest Forfeiture Ever Obtained Through a Kleptocracy Action

The Department of Justice has forfeited more than $480 million in corruption proceeds hidden in bank accounts around the world by former Nigerian dictator Sani Abacha and his co-conspirators



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Owner of Costa Rican Call Center Pleads Guilty to Defrauding Elderly Through Sweepstakes Scam

A dual United States-Costa Rican citizen pleaded guilty today for his role in a $1.88 million sweepstakes fraud scheme that defrauded hundreds of elderly Americans.



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BASF Launches Breakthrough Absorption Technology as GOED Raises Bioavailability Challenge to Omega-3 Industry

BASF recently announced the launch of Accelon™ absorption accelerating technology, developed as a breakthrough solution to the bioavailability challenge of today’s omega-3 supplements.




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Parry Nutraceuticals, Valensa Expand Microalgae Plans Through Joint Venture with Synthite Industries

Valensa International announced today a joint venture agreement between Valensa’s parent company EID Parry and Synthite Industries Ltd., expanding plans to lead development and distribution of value-added microalgae extracts.




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APEC SME Ministers Commit to Inclusion Through Digital Transformation

Ministers convened this week in Concepcion to talk about one of the most underrepresented but vital business sectors of the region.




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Fortress joins KRAS race through Columbia University deal

Fortress Biotech has licensed a treatment for KRAS-driven cancers from Columbia University. Sticking to its blueprint, Fortress has set up a new biotech, Oncogenuity, to advance the preclinical asset and work to generate more oligonucleotides from the underlying platform.




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Google Says Most Of Its Employees Will Likely Work Remotely Through End of Year

The tech giant announces it is extending its previous work-from-home plans for most of its staff and will begin reopening offices this summer.




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Drive-through celebrations and car parades nixed in Santa Clara County

The coronavirus outbreak has forced the cancellation of myriad life events. Santa Clara County won't even let you celebrate in your car now.




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Did coronavirus spread through a nail salon? Newsom said so, and now owners fear for their business

Did community spread of the coronavirus start at a nail salon? Governor said so, and now immigrant owners worry about getting business.




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Igniting autophagy through the regulation of phase separation




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MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal




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Through the laser mirror




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Breaking through the glioblastoma micro-environment via extracellular vesicles




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100 years of influenza research seen through the lens of Covid-19




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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




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Nanomolar-scale, high throughput chemical synthesis of drug-like molecules

A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds.




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FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome




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Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy




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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Paired TCR discovery in high throughput




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HPCA Hosts COP25 Side Event Focused on Reducing GHG Emissions through Carbon Pricing

As negotiators from around the world arrived in Madrid for the second week of the 25th UN Climate Change Conference (COP-25), the Harvard Project on Climate Agreements hosted an official COP side event on Dec. 9 focusing on the potential for reducing greenhouse-gas (GHG) emissions through the use of carbon pricing.




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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Mitigating osteonecrosis of the jaw (ONJ) through preventive dental care and understanding of risk factors




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HPCA Hosts COP25 Side Event Focused on Reducing GHG Emissions through Carbon Pricing

As negotiators from around the world arrived in Madrid for the second week of the 25th UN Climate Change Conference (COP-25), the Harvard Project on Climate Agreements hosted an official COP side event on Dec. 9 focusing on the potential for reducing greenhouse-gas (GHG) emissions through the use of carbon pricing.




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Correction to ‘Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation’




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Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal




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'It is a pity that PPPs are not working too well...India badly needs infrastructure and half of that investment has to come through PPPs'

Gustavo Manuel speaks about killing of soldier in London, business with India and football.




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Innovating through Cloud Computing


Technology offers the greatest source for innovation in the public sector and one of the best examples falls within the area of cloud computing. As I noted in a recent paper, the U.S. federal government spends nearly $76 billion each year on information technology, and $20 billion of that is devoted to hardware, software, and file servers. Traditionally, computing services have been delivered through desktops or laptops operated by proprietary software. But new advances in cloud computing have made it possible for public sector agencies alike to access software, services, and data storage through remote file servers.

I looked at possible cost savings a federal agency might expect from migrating to the cloud. After undertaking case studies of government agencies that made the move, I found that the agencies generally saw between 25 and 50 percent savings in moving to the cloud. Public officials can save money by reducing the number of file servers they need to purchase, cutting software costs, relying on fewer information technology specialists, and improving the efficiency of their data storage utilization.

In 2008, Washington, D.C. city government shifted many of its 38,000 employee email services across 86 agencies to the cloud, and the migration saved 48 percent on email expenditures. In 2009, the city of Los Angeles moved email service for its 30,000 employees to the cloud. An analysis undertaken by City Administrative Officer Miguel Santana for the City Council found that the five-year costs of running the new Google system would be $17,556,484, which was 23.6 percent less than the $22,996,242 for operating GroupWise during that same period. And in terms of personnel savings, the city needed nine fewer people in its information technology department.

The U.S. Air Force 45th Space Wing is responsible for launching and tracking unmanned space vehicles from Cape Canaveral Air Force Station and employs more than 10,000 workers. The Wing had 60 distinct file servers, but found that it utilized only 10 percent of central processing unit capacity. Commanders modernized their system and saved $180,000 per year in annual computing costs. In addition, the unit saved money by not buying new hardware or deploying new software. These are just some of the ways the government is using technology to save money and increase efficiency of its operations.

Authors

Image Source: © HANNIBAL HANSCHKE / Reuters
     
 
 




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Leveling the playing field between inherited income and income from work through an inheritance tax

The Problem The core objectives of tax policymaking should be to raise revenue in an efficient and equitable manner. Current taxation of estates and gifts (and nontaxation of inheritances) fails to meet these goals, perpetuating high levels of economic inequality and impeding intergenerational mobility. The current system also provides an intense incentive to delay realization of capital gains…

       




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Presidents Obama and George H.W. Bush: Building Bridges Through Service


President Barack Obama’s visit to the George Herbert Walker Bush Library in College Station, Texas this week highlights the crucial role of America’s volunteer traditions in addressing critical issues at home and abroad. The two presidents will commemorate the 20th anniversary of the Points of Light movement, championed by the 41st president, and advance the United We Serve initiative of President Obama.

Michelle Nunn, CEO of Points of Light Institute and daughter of former Democratic Senator Sam Nunn noted in Huffington Post that “demand, idealism and presidential impact are leading American volunteerism to its…most important stage – the movement of service to a central role in our nation’s priorities.”

The bipartisan nature of America’s vibrant service movement is also reflected in the landmark Kennedy-Hatch Serve America Act signed into law by President Obama earlier this year and pending Global Service Fellowship legislation introduced by Senators Feingold and Voinovich.

In a recent Brookings Global Views policy brief, “International Volunteer Service: A Smart Way to Build Bridges,” Lex Rieffel, Kevin Quigley and I articulate policy options for the new administration to advance President Obama’s call for engaging service on the global level. President Obama’s speech in Cairo on June 4 called for turning “dialogue into interfaith service, so bridges between peoples lead to action – whether it is combating Malaria in Africa, or providing relief for a natural disaster.”

Following the president’s Cairo speech, the administration assembled a laudable Global Engagement Initiative across the administration to implement and track results in scaling up initiatives of service and interfaith action. The potency of coupling American service with foreign assistance was documented in Indonesia and Bangladesh through successive Terror Free Tomorrow polls showing increased favorable ratings for our nation and decreased support for terrorism.

The Building Bridges Coalition has organized an impressive array of over 210 organizations dedicated to expanding American volunteerism internationally, as part of a new “Service World” policy coalition gearing up for the 50th anniversary of the Peace Corps. This new “international service 2.0” incorporates NGOs and faith-based groups, universities and corporations as new development actors advocating multilateral service and achieving impacts on issues ranging from Malaria to peacebuilding and climate change.

A Foundation Strategy Group report commissioned by Brookings and Pfizer, “Volunteering for Impact” assessed best practices in the increasing array of international corporations engaging volunteers such as IBM’s Corporate Service Corps, GE Volunteers and Pfizer’s Global Health Fellows.

Around the globe, initiatives such as Cross Cultural Solutions and an emerging global service and peacebuilding alliance in hot spots from Kenya to Mindanao are giving substance to the president’s call in Cairo. The collaboration of Presidents Clinton and G.H.W. Bush on humanitarian assistance after the tsunami, and this week’s service dedication with the Obama administration and former President Bush, bode well for the bipartisan extension of our nation’s noble voluntary service traditions in the international context where they are urgently needed.

Image Source: © Jim Young / Reuters
     
 
 




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Amped in Ankara: Drug trade and drug policy in Turkey from the 1950s through today

Key Findings Drug trafficking in Turkey is extensive and has persisted for decades. A variety of drugs, including heroin, cocaine, synthetic cannabis (bonsai), methamphetamine, and captagon (a type of amphetamine), are seized in considerable amounts there each year. Turkey is mostly a transshipment and destination country. Domestic drug production is limited to cannabis, which is […]

      
 
 




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Through the looking glass: An Israeli perspective on American politics


“It’s probably the most interesting presidential election I’ve seen in my lifetime,” I said to an American friend the moment I arrived to Washington. My friend was upset. “For you it’s interesting,” he said. “For us it’s painful.”

“What you’ve just said rings a bell,” I said. “This is exactly, word for word, what I keep saying to foreign journalists who come to Israel to write a story.” Covering politics in Israel is like covering a professional wrestling fight: the rivals exchange numerous hits, shout at each other, humiliate each other, disregard every rule, but in most cases the outcome is known in advance.

Covering politics in Israel is like covering a professional wrestling fight...in most cases the outcome is known in advance.

Americans are supposed to play their political game in a cooler way. At least, this is the impression a foreign correspondent get when he lands here, directly from the boiling quarrels of the Middle East. 

I had the opportunity to cover almost all the U.S. presidential campaigns since Jimmy Carter’s victory over Gerald Ford in 1974. I loved it—I loved the town halls and the rallies in remote places, where people are kind and willing to answer every clueless question from a foreign reporter; I loved the access to the candidates, weeks and months before the secret service builds a wall between them and real life; I loved the hectic atmosphere, described so well in the “Making of the President” books by Theodore H. White; I loved to see how little-known candidates like Bill Clinton or Barack Obama evolve, grow, and flourish; and I enjoyed every chapter: the spins, the buzz, the role played by big money.

The election campaign seems to be different this time: It looks different; it sounds different. The key word is anger—anger dominated the selection process in both parties. Angry voters elected angry candidates. If a candidate was not angry enough—e. g. Jeb Bush—the voters judged him unfit for the job.

The election campaign seems to be different this time: It looks different; it sounds different. The key word is anger.

An accidental tourist like me pauses here for a long list of questions: how do we quantify anger? Is it limited to the ballots or can it evaporate at some point and turn into violent acts, as Donald Trump has insinuated time and again? Is it a reflection of the bitterness of specific, limited constituencies or is it something much more widespread, an outrage of a generation or a class of Americans who feel that they were betrayed by the political and business elite, by the establishment? How to explain the Trump phenomenon, the Sanders phenomenon? 

The obvious answer is the economic collapse of 2008: the people who fell victim to the 2008 crisis, who lost a home or a job or had to give up college for their children are now in revolt. Why now and not earlier? Because four years ago they were struggling to survive; they were busy. Politicizing emotions is a long process; sometimes it takes years.

Tip O'Neill, speaker of the house in the second half of the previous century, taught us that all politics is local. There is a lot of truth in it even today, but is it the whole truth? In the flat world of 2016, local politics are executed in a global way. All politics are local and global at the same time. Political actions spread from country to country like the Zika virus, using social media as carriers.

The young Sanders supporters I met in Brooklyn, during the last Democratic debate, were not much different from the young Israelis I met in Tel Aviv in the summer of 2011, when hundreds of thousands of Israelis took to the streets. Those Israelis complained about similar things: high prices, loss of employment security, difficulty getting a decent job, and the ever-growing gap between expectations and reality. They were promised to live in the land of opportunity; the opportunity was not there—not for them.

Politicizing emotions is a long process; sometimes it takes years.

They complained bitterly about the banks and the major corporations. They became so big that the government has no choice but to subsidize them when they lose money. And the people who run them get huge salaries and bonuses on the expense of the shareholders and the general public. Israel used to be a social democratic society, with a strong middle class and a relatively narrow gap between rich and poor. Now the rich are very rich and get richer, and the less fortunate are left behind.

The protest was fueled by social media: another similarity between Tel Aviv and the young voters in Brooklyn and elsewhere. The brazenness, the bluntness, the rudeness of the social media culture affected the political discourse. It became less cordial and more personal. 

Israelis were not alone. The Arab Spring predated the Israeli Summer. Greece and Spain followed. Occupy Wall Street, a smaller, more radical protest movement, appeared on the streets of major American cities in the fall of 2011. It was inspired by the protests in the Arab countries and in Spain. The demonstrators faded away after a while, but they left their mark: political agendas have changed dramatically, governments fell, conventions were shuttered. It remains to be seen if and how they will contribute to social justice and equality.

In Israel, the demand for social justice captured a prominent place on the national agenda; several activists in the protest movement were elected to the Knesset; the rhetoric has changed, priorities didn't. Not really. Most Israelis were not prepared for a revolution, not even a moderate revolution, Bernie Sanders-style. 

I have no way to know what lies ahead for the American society. What I can see so far is a unique electoral season, characterized by unusual, almost bizarre candidates, their qualification for the job questionable, and a long, destructive battle over votes. For many Americans it is painful. People in other countries can only wonder: is it the best America is able to produce? 

Authors

  • Nahum Barnea