Wink customers will soon have to pay a monthly subscription fee to access any of the smart home hardware that they have purchased.

Ministry opportunities in Hungary open up the mission experience for families with younger children.

Marcela (Argentina) experienced the power of God working through her while on a mission trip in Israel.

The care the head teacher of Chiyembekezo School shows to her pupils even outside the classroom has a ripple effect on the larger community.

Getting the whole family involved in a short term missions trip is an unforgettable experience!

Joblessness now stands at the most since the Great Depression era of the 1930s after the coronavirus pandemic brought the US economy to a standstill.

OM EAST responds to the need for Christian books in the Georgian language.

Olger Morales shares his testimony of how he came to work in OM full-time after participating in numerous short-term outreaches.

A Chicago-based former Little League team has filed a lawsuit against Little League International over the organization's decision to strip the team's United States championship earlier this year.

Studies have found that the degree of detail with which palliative care is described and the order in which options are presented can affect end-of-life decisions. None of these studies, though, involved decisions regarding very premature infants.

Unlike other end-of-life decisions, those regarding extremely premature infants are influenced neither by the degree of detail nor order of presentation of management options. Deep-seated values embodied in the reasons given for these choices suggest why they are so robust. (Read the full article)

Treatment of adolescent migraine remains a significant unmet medical need. In adults, the combination of sumatriptan and naproxen sodium has demonstrated superior efficacy, with similar tolerability, to its components in the acute treatment of migraine.

This study constitutes the first large-scale, placebo-controlled evidence for the acute relief of adolescent migraine pain and associated symptoms with an oral medication. (Read the full article)

A wide variety of prescription drugs are prescribed to US children. Although one of the steps in assessing the risk/benefit of therapies in the pediatric population is to understand how they are used, pediatric drug utilization is not well characterized.

By using large prescription databases, this study examines the frequency and patterns of national outpatient drug utilization (acute and chronic medications) in US infants, children, and adolescents for 2002 through 2010. (Read the full article)

Filling a prescription is the first step in medication adherence. Unfilled prescriptions are a documented component of nonadherence in adult and pediatric emergency departments and family practices. No one has reported the proportion of unfilled prescriptions in pediatric primary care.

This study identifies the proportion of unfilled prescriptions in a large sample of primary care pediatric patients. It describes clinical and demographic factors associated with prescription filling and suggests that electronic prescribing may improve adherence. (Read the full article)

Self-medication with antibiotics available without prescription is among the main causes of antibiotic misuse in the developing world and is associated with antibiotic resistance. Inappropriate antibiotic prescription is common in children. Patient expectations seem to influence physicians’ advice.

This study demonstrates that even in places where antibiotics are unregulated, improving physician prescribing habits could reduce irrational use overall and also future caregiver-driven misuse. Physician training in adequate antibiotic prescription could be a cost-effective intervention in these settings. (Read the full article)

Medication ingestions are increasing among children despite a number of public health interventions. The majority of these poisonings are related to prescription as opposed to over-the-counter medications.

Rising rates of poisonings in children are strongly correlated with rising use of hypoglycemics, antihyperlipidemics, β-blockers, and opioids among adults. These events are associated with considerable health care utilization, both in terms of emergency department visits and hospital admissions. (Read the full article)

Unintentional overdose and emergency department visits secondary to nonmedical use of prescription drugs are on the rise with peak age of onset in midadolescence for these risk behaviors. Also, risk behaviors, such as substance use and violence, tend to cluster.

Approximately 1 in 10 adolescents or young adults using the emergency department endorse nonmedical prescription opioid or sedative use in the past year. Rates of current opioid or sedative prescriptions are low among this group. (Read the full article)

Childhood obesity poses a serious threat to human health. Obesity is caused by genetic and environmental factors and linked to type 2 diabetes and cardiovascular disease. Pediatric obesity cohorts aim at understanding early events in the pathophysiology of obesity-related complications.

Cohort subjects are examined at consecutive visits, including measurements of glucose tolerance and hormones regulating nutrient handling (enhanced glucose tolerance tests) and body composition (MRI and bioimpedance). Mechanisms causing obese children to progress to type 2 diabetes are delineated. (Read the full article)

Owing to genetic variability in its metabolism, codeine can lead to fatal toxicity or inadequate treatment in pediatric subpopulations and several guidelines have recommended against its use in children. Little is known about codeine prescribing for children in the United States.

There has been a small decline in pediatric codeine prescriptions overall in emergency departments, but no change in prescription for children who have cough or upper respiratory infection, despite professional recommendations against this practice. Substantial numbers of children are being prescribed codeine annually. (Read the full article)

Prescribing patterns in the US pediatric population are changing but not uniformly. A detailed examination of prescription variation is needed to better understand pharmacotherapy of children and to inform future exploration of the causes and consequences of diverse practices.

We examine pediatric pharmacotherapy and quantify payer type differences and small geographic area variation. Substantial payer-type differences and regional variations were found, likely reflecting local practice cultures. Variation was greatest for medications used in situations of diagnostic and therapeutic uncertainty. (Read the full article)

Despite child-resistant packaging requirements for most medications and safe storage education for all medicines, tens of thousands of young children are brought to emergency departments and thousands are hospitalized annually after ingesting prescription medications. Targeted prevention efforts may be needed.

Twelve medications were implicated in nearly half of hospitalizations for prescription medication ingestions. Buprenorphine and clonidine were most commonly implicated and had the highest hospitalization rates when accounting for outpatient use. Prevention efforts should focus on most commonly implicated medications. (Read the full article)

Although opioid pain relievers are commonly prescribed in pregnancy, their association with neonatal outcomes is not well described. Further, factors associated with development of neonatal abstinence syndrome, a neonatal opioid withdrawal syndrome is inadequately understood.

Prescription opioid use in pregnancy is common and strongly associated with neonatal complications. Antenatal cumulative prescription opioid exposure, opioid type, tobacco use, and selective serotonin reuptake inhibitor use increase the risk of neonatal abstinence syndrome. (Read the full article)

Legitimate opioid is a risk factor for subsequent misuse of opioids among adults. This study provides the first population-based estimate of the risk of future opioid misuse associated with legitimate opioid use among adolescents.

Use of prescribed opioids before the 12th grade is independently associated with future opioid misuse among patients with little drug experience and who disapprove of illegal drug use. (Read the full article)

It was far too easy to accidentally start an app subscription if you own an iPhone with Touch ID. Apple just solved the problem with a pop-up.

Aspergillus niger, the third species responsible for invasive aspergillosis has been considered as a homogeneous species until DNA-based identification uncovered many cryptic species. These species have been recently reclassified into the Aspergillus section Nigri. However little is yet known among the section Nigri about the species distribution and the antifungal susceptibility pattern of each cryptic species. A total of 112 clinical isolates collected from 5 teaching hospitals in France and phenotypically identified as A. niger were analyzed. Identification to the species level was carried out by nucleotide sequence analysis. The Minimum Inhibitory Concentrations (MICs) of itraconazole, voriconazole, posaconazole, isavuconazole and amphotericin B were determined by both the EUCAST and gradient concentration strips methods. Aspergillus tubingensis (n=51, 45.5%) and A. welwitschiae (n=50, 44.6%) were the most common species while A. niger accounted for only 6.3% (n=7). The MICs of azoles drugs were higher for A. tubingensis than for A. welwitschiae. The MIC of amphotericin B was 2 mg/L or less for all isolates. Importantly, MICs determined by EUCAST showed no correlation with those determined by gradient concentration strips methods, these latter being lower than the former (Spearman's rank correlation tests ranging - depending on the antifungal agent - from 0.01 to 0.25; p>0.4). In conclusion, A. niger should be considered as a minority species in the section Nigri. The differences in MICs between species for different azoles underline the importance of accurate identification. Significant divergences in the determination of MIC between EUCAST and gradient concentration strips methods require further investigation.

While we wait for Apple Arcade to launch for iOS devices, Google is preparing its own app/game subscription service for Android called Play Pass.

A family of four was caught flouting lockdown restrictions after attempting to travel to Motherwell for a mini-break.

Staff from NHS England have been asked to travel hundreds of miles to Scotland to be tested for coronavirus, according to reports.

A family who was fined for travelling more than 400 miles for the bank holiday weekend have been slammed online by politicians and Scots.

Chinese manufacturer TCL will no longer make BlackBerry-branded phones, nor will it have the right to 'design, manufacture or sell any new BlackBerry mobile devices' after August 2020.

Snow and record cold are in the forecast for New York City and the Northeast Saturday.

As students begin gearing up for their spring break travels, the University is reminding travelers to take precautions to stay healthy and avoid illnesses.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

A look back at prior attempts to renew the federal law makes one thing clear: We're drifting further and further away from the idea of a strong federal role in K-12 accountability.

Not content to dominate the high-end desktop (HEDT) market with its new 32-core CPU, today AMD announced the upcoming launch of its most powerful Threadripper yet: the 64-core, 128-thread Ryzen Threadripper 3990X.

Unveiled here at CES, the new Ryzen 4000 CPU family is the first to use AMD's cutting-edge 7-nanometer production process.

The Dell PowerEdge T30 is back at $299, the AMD Ryzen Threadripper 2920X is just $382, and the 55-inch LG B8 OLED 4K TV is only $1,047.

A district in Washington state has halted all international field trips over concerns students in the country illegally wouldn't be able to get back in.

Education Week has teamed up with Roadtrip Nation to send a group of teachers across the country in a green RV. Here's what you need to know.

Businesses can avoid workplace disputes and CCMA hearings by taking a number of precautions, labour experts say.

Books played an important role in Aslan's salvation. Now he provides literature to other Central Asians.

The federal government’s newly-revamped tool can lead to increased costs. Commissioner Trinidad Navarro has released a rare consumer alert regarding Medicare’s newly-updated Prescription Plan Finder. Throughout this year’s open enrollment period, which ends on December 7, the Department of Insurance has received numerous complaints about the tool and anticipated prescription drug costs. The Prescription Plan […]

Statistics from the Division of Professional Regulation, which licenses controlled substance prescribers, show a 12-percent drop in opioid prescriptions statewide compared to the first quarter of 2017. The number of Delaware patients being treated with opioid medications has also declined by 8 percent over the same time period, the division reports.

Delaware’s wildland fire crew is returning to the First State after successfully battling wildfires in Colorado and Wyoming. The Delaware Forest Service dispatched the firefighters to Colorado on July 25. Their first assignment was assisting Colorado’s Bureau of Land Management on the 492-acre Milk Fire near Craig, Colorado. Next, they were sent by the Rocky Mountain Geographic Area Coordination Center to the 1,287-acre Tokewanna Fire near Mountain View, Wyoming. Finally, on August 4, they were dispatched to the 12,276-acre Whit Fire, located east of Yellowstone National Park near Cody, Wyoming.

Agency: GSS Closing Date: 6/2/2020

The number of prescriptions for opioid medications in Delaware, as well as the total quantity of opioids dispensed, have dropped significantly in the 12 months since the Department of State enacted stricter prescribing regulations to help combat the opioid crisis statewide.

Sat., Oct. 26, 2019: Delaware residents can safely dispose of their unused or expired prescription medications at designated sites throughout the state as part of the 18th National Prescription Drug Take-Back Day.

Please use public transit for essential trips only. When you need to get to work, to the grocery store or pharmacy, or to other critical destinations, we’re here for you. If your trip isn’t essential, please stay home and leave the seat for a healthcare worker or someone who needs critical access.

If you are feeling sick, please do not take public transit or visit public facilities. For more information on the state's response to the Coronavirus, visit de.gov/coronavirus.

Thank you.