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The effects of aloe emodin-mediated antimicrobial photodynamic therapy on drug-sensitive and resistant Candida albicans

Photochem. Photobiol. Sci., 2020, 19,485-494
DOI: 10.1039/C9PP00352E, Paper
Wenpeng Ma, Chengcheng Liu, Jiao Li, Ming Hao, Yanhong Ji, Xiaoyan Zeng
Aloe emodin-mediated antimicrobial photodynamic therapy effectively inactivated drug-sensitive and resistant C. albicans and caused damage to the cell wall, cytoplasm, and nucleus.
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Multifunctional cubic liquid crystalline nanoparticles for chemo- and photodynamic synergistic cancer therapy

Photochem. Photobiol. Sci., 2020, Advance Article
DOI: 10.1039/C9PP00449A, Paper
Sébastien Jenni, Giacomo Picci, Marco Fornasier, Marianna Mamusa, Judith Schmidt, Yeshayahu Talmon, Angélique Sour, Valérie Heitz, Sergio Murgia, Claudia Caltagirone
Multifunctional lipidic cubic liquid crystalline nanoparticles for potential cancer therapy were engineered by conjugating a porphyrin-based photosensitizer to the block copolymer Pluronic F108 and loading them with the antineoplastic drug Docetaxel.
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Food-based strategies for prevention of vitamin D deficiency as informed by vitamin D dietary guidelines, and consideration of minimal-risk UVB radiation exposure in future guidelines.

Photochem. Photobiol. Sci., 2020, Accepted Manuscript
DOI: 10.1039/C9PP00462A, Paper
Kevin D Cashman
There is widespread acknowledgement of the presence of vitamin D deficiency in the community and the pressing need to address this. From a public health perspective, emphasis has been placed...
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Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019

Photochem. Photobiol. Sci., 2020, Advance Article
DOI: 10.1039/D0PP90011G, Perspective
G. H. Bernhard, R. E. Neale, P. W. Barnes, P. J. Neale, R. G. Zepp, S. R. Wilson, A. L. Andrady, A. F. Bais, R. L. McKenzie, P. J. Aucamp, P. J. Young, J. B. Liley, R. M. Lucas, S. Yazar, L. E. Rhodes, S. N. Byrne, L. M. Hollestein, C. M. Olsen, A. R. Young, T. M. Robson, J. F. Bornman, M. A. K. Jansen, S. A. Robinson, C. L. Ballaré, C. E. Williamson, K. C. Rose, A. T. Banaszak, D.-P. Häder, S. Hylander, S.-Å. Wängberg, A. T. Austin, W.-C. Hou, N. D. Paul, S. Madronich, B. Sulzberger, K. R. Solomon, H. Li, T. Schikowski, J. Longstreth, K. K. Pandey, A. M. Heikkilä, C. C. White
This assessment provides an update of the interactive effects of solar ultraviolet (UV) radiation, stratospheric ozone, and climate change on human health, terrestrial and aquatic ecosystems, biochemical cycles, air quality, and material damage.
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Palladium porphyrin complexes for photodynamic cancer therapy: effect of porphyrin units and metal

Photochem. Photobiol. Sci., 2020, Advance Article
DOI: 10.1039/C9PP00363K, Paper
Jingran Deng, Haolan Li, Mengqian Yang, Fengshou Wu
The ROS generation ability and photocytotoxicity of the synthesized porphyrin compounds were enhanced with the number of porphyrin units in the photosensitizers.
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The Equitable Distribution of COVID-19 Therapeutics and Vaccines

This Viewpoint proposes a framework for international cooperation among governments and organizations to replace competition and hoarding with equitable global distribution of COVID-19 therapeutics and vaccines as they are developed.




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Surgery in a Time of Uncertainty—The Need for Universal Respiratory Precautions in the Operating Room

This Viewpoint proposes that universal respiratory precautions in the operating room—use of respirators with face masks and eye protection—could protect staff from possible coronavirus disease 2019 (COVID-19) infection and facilitate resumption of elective surgeries canceled during the first wave of the pandemic.




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The Greatest Generation

In this narrative medicine essay, the author discusses the inaccuracies of generational stereotypes and unfounded criticisms about trainees, and the problems that faculty members who voice these criticisms can cause among physicians.




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Mentoring in the #MeToo Era

In this narrative essay, the author wonders what effect the #metoo phenomenon will have on mentoring between male mentors and junior female trainees and faculty and recalls male mentors who were supportive of her and other women colleagues’ professional development in a plea for diversity and inclusion among leaders in medicine that supports the entire academic medical community.




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A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

J. Mater. Chem. B, 2020, 8,3502-3505
DOI: 10.1039/C9TB02459J, Communication
Zhenhua Liu, Yujie Cao, Xiaona Zhang, Huazhen Yang, Yujie Zhao, Wen Gao, Bo Tang
A novel dual-targeted CeO2–DNA nanosensor by modifying with folic acid (FA) and CD36 antibody was designed.
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Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

J. Mater. Chem. B, 2020, 8,3606-3615
DOI: 10.1039/C9TB02439E, Paper
Iene Rutten, Devin Daems, Jeroen Lammertyn
Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.
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Flexible and stretchable dual mode nanogenerator for rehabilitation monitoring and information interaction

J. Mater. Chem. B, 2020, 8,3647-3654
DOI: 10.1039/C9TB02466B, Paper
Zhuo Liu, Qiang Zheng, Yue Shi, Lingling Xu, Yang Zou, Dongjie Jiang, Bojing Shi, Xuecheng Qu, Hu Li, Han Ouyang, Ruping Liu, Yuxiang Wu, Yubo Fan, Zhou Li
Sensors with flexibility and stretchability are the key functional modules of converter between mechanical motions and electric signals for intelligent robots and rehabilitation training systems.
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Nanomaterial-based biosensors for DNA methyltransferase assay

J. Mater. Chem. B, 2020, 8,3488-3501
DOI: 10.1039/C9TB02458A, Review Article
Fei Ma, Qian Zhang, Chun-yang Zhang
We review the recent advances in the development of nanomaterial-based biosensors for DNA methyltransferase assay.
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Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

J. Mater. Chem. B, 2020, 8,3192-3212
DOI: 10.1039/C9TB02578B, Review Article
Rashaad A. Husain, Snigdha Roy Barman, Subhodeep Chatterjee, Imran Khan, Zong-Hong Lin
An overview of enhancement strategies for highly sensitive ECL-based sensing of bioanalytes enabling early detection of cancer.
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Toehold-regulated competitive assembly to accelerate the kinetics of graphene oxide-based biosensors

J. Mater. Chem. B, 2020, 8,3683-3689
DOI: 10.1039/C9TB02454A, Paper
Huan Du, Junbo Chen, Jie Zhang, Rongxing Zhou, Peng Yang, Xiandeng Hou, Nansheng Cheng
With toehold-regulation, the kinetics of graphene oxide-based biosensors can be accelerated.
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A general strategy for designing NIR-II emissive silk for the in vivo monitoring of an implanted stent model beyond 1500 nm

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02685A, Paper
Zhiming Deng, Junqing Huang, Zhenluan Xue, Mingyang Jiang, Youbin Li, Songjun Zeng
The NIR-II emissive silk is explored by a general feeding strategy for NIR-II imaging guided in situ monitoring of the implanted biological stent model made from silk.
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Development of CeO2 nanodot encrusted TiO2 nanoparticles with reduced photocatalytic activity and increased biocompatibility towards a human keratinocyte cell line

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00629G, Paper
Alexander Morlando, Marcela Chaki Borrás, Yaser Rehman, Shahnaz Bakand, Philip Barker, Ronald Sluyter, Konstantin Konstantinov
Low photocatalytic CeO2/TiO2 nanocomposite particles with high UV attenuation and reduced ROS generation for application in sunscreen products.
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Rapidly dissolving microneedle patch for synergistic gene and photothermal therapy of subcutaneous tumor

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00105H, Paper
Qinan Xu, Xinfang Li, Peng Zhang, Youxiang Wang
Synergistic gene and photothermal therapy conducted by p53 DNA/IR820 MN patch may be a promising strategy for subcutaneous tumor treatments.
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Multi-Stimuli Responsive Polymeric Prodrug Micelles for Combined Chemotherapy and Photodynamic Therapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00539H, Paper
Cheng Hu, Weihua Zhuang, Tao Yu, Liang Chen, Zhen Liang, Gaocan Li, Yunbing Wang
Nowadays, cancer therapy faces severe challenges on boosting therapeutic efficiency and reducing the side effects of drugs. To overcome these challenges, herein multifunctional polymeric prodrug micelles with combining chemotherapy and...
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Fluorinated porphyrin-based theranostics for dual imaging and chemo-photodynamic therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00083C, Paper
Huaibin Zhang, Shaowei Bo, Kai Zeng, Jie Wang, Yu Li, Zhigang Yang, Xin Zhou, Shizhen Chen, Zhong-Xing Jiang
A modular strategy facilitates the convenient and standardized preparation of multifunctional theranostics for cancer therapy.
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Seedless Synthetic Branched Gold Nanoshell for Chemo-thermal Antitumor Therapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00891E, Paper
Lei Li, Yihan Fu, Zichuang Xu, Xuwu Zhang, Zining Hao, Yaqian He, Wenbin Gao, Dawei Gao
Gold nanomaterials (GNMs) were used in photothermal therapy due to their superior optical properties and excellent biocompatibility. However, the complex preparation process of seed-mediated growth limits further clinical applications of...
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Glutathione- and light-controlled generation of singlet oxygen for triggering drug release in mesoporous silica nanoparticles

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00636J, Paper
Roy C. H. Wong, Dennis K. P. Ng, Wing-Ping Fong, Pui-Chi Lo
An activatable phthalocyanine-based photosensitiser and a singlet-oxygen-triggered doxorubicin releasing system have been incorporated into mesoporous silica nanoparticles, which can release the encapsulated doxorubicin in a controllable manner.
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Progress in biomimetic leverages for marine antifouling using nanocomposite coatings

J. Mater. Chem. B, 2020, 8,3701-3732
DOI: 10.1039/C9TB02119A, Review Article
Mohamed S. Selim, Sherif A. El-Safty, Mohamed A. Shenashen, Shimaa A. Higazy, Ahmed Elmarakbi
Because of the environmental and economic casualties of biofouling on maritime navigation, modern studies have been devoted toward formulating advanced nanoscale composites in the controlled development of effective marine antifouling self-cleaning surfaces.
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Recent advances of nanomedicines for liver cancer therapy

J. Mater. Chem. B, 2020, 8,3747-3771
DOI: 10.1039/C9TB02871D, Review Article
Xiaoqin Chi, Kun Liu, Xiangjie Luo, Zhenyu Yin, Hongyu Lin, Jinhao Gao
This review highlights recent advancements in nanomedicines for liver cancer therapy.
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Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

J. Mater. Chem. B, 2020, 8,3789-3800
DOI: 10.1039/D0TB00046A, Paper
Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.
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Tumor-mediated shape-transformable nanogels with pH/redox/enzymatic-sensitivity for anticancer therapy

J. Mater. Chem. B, 2020, 8,3801-3813
DOI: 10.1039/D0TB00143K, Paper
Dong Zhou, Sainan Liu, Yongjun Hu, Shiwei Yang, Bing Zhao, Kaikai Zheng, Yuhong Zhang, Peixin He, Guoyan Mo, Yulin Li
Tumor-mediated shape-cleavable nanogels can release drug-carrying ultrasmall nanovesicles through tumor tissue depth, which together with their pH/redox/enzymatic-multistimulative drug release smartness results in a synergistic antitumor efficacy.
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Fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy

J. Mater. Chem. B, 2020, 8,3772-3788
DOI: 10.1039/D0TB00262C, Review Article
Yu Huang, Feng Qiu, Rongjun Chen, Deyue Yan, Xinyuan Zhu
In this Review, recent advances in fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy are described, and the current challenges and perspectives in this emerging field are also discussed.
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Nanoclay-functionalized 3D nanofibrous scaffolds promote bone regeneration

J. Mater. Chem. B, 2020, 8,3842-3851
DOI: 10.1039/C9TB02814E, Paper
Qingqing Yao, Kirby E. Fuglsby, Xiao Zheng, Hongli Sun
A nanoclay-enriched 3D nanofibrous biomimetic scaffold with strong bone regenerative ability by virtue of its improved mechanical properties, osteoconductivity, and drug binding capacity was developed.
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Modified gaphene oxide (GO) particles in peptide hydrogels: a hybrid system enabling scheduled delivery of synergistic combinations of chemotherapeutics

J. Mater. Chem. B, 2020, 8,3852-3868
DOI: 10.1039/D0TB00064G, Paper
John D. Schneible, Kaihang Shi, Ashlyn T. Young, Srivatsan Ramesh, Nanfei He, Clay E. Dowdey, Jean Marie Dubnansky, Radina L. Lilova, Wei Gao, Erik Santiso, Michael Daniele, Stefano Menegatti
Composite material enabling the delivery of synergistic combination of doxorubicin and gemcitabine against breast cancer with molar and kinetic precision.
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Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy

J. Mater. Chem. B, 2020, 8,3918-3928
DOI: 10.1039/D0TB00285B, Paper
Lu Lu, Bing Li, Chuanchuan Lin, Ke Li, Genhua Liu, Zengzilu Xia, Zhong Luo, Kaiyong Cai
A redox-responsive drug carrier with asialoglycoprotein receptor (ASGPR) targeting is fabricated for liver tumor therapy.
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Biodegradable MnFe-hydroxide nanocapsules to enable multi-therapeutics delivery and hypoxia-modulated tumor treatment

J. Mater. Chem. B, 2020, 8,3929-3938
DOI: 10.1039/D0TB00243G, Paper
Linhua Liao, Dong Cen, Yike Fu, Bin Liu, Chao Fang, Yifan Wang, Xiujun Cai, Xiang Li, Hao Bin Wu, Gaorong Han
Fine nanocapsules based on MnFe hydroxides, showing high loading capacity, O2 induction and biodegradation, were synthesized for effective synergistic therapies.
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A near-infrared light-responsive multifunctional nanocomposite hydrogel for efficient and synergistic antibacterial wound therapy and healing promotion

J. Mater. Chem. B, 2020, 8,3908-3917
DOI: 10.1039/D0TB00361A, Paper
Na Yang, Ming Zhu, Guochao Xu, Ning Liu, Cong Yu
A multifunctional nanocomposite hydrogel for synergistic antibacterial wound therapy and healing promotion.
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“Watson–Crick GC”-inspired supramolecular nanodrug of methotrexate and 5-fluorouracil for tumor microenvironment-activatable self-recognizing synergistic chemotherapy

J. Mater. Chem. B, 2020, 8,3829-3841
DOI: 10.1039/D0TB00468E, Paper
Meijin Chen, Shiduan Chen, Fukai Zhu, Fanfan Wang, Haina Tian, Zhongxiong Fan, Sunkui Ke, Zhenqing Hou, Yang Li
The “Watson–Crick G≡C”-inspired carrier-free nanodrug have excellent tumor microenvironment-triggered active self-targeting ability and enhanced synergistic chemotherapeutic effects.
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Tunable layer-by-layer films containing hyaluronic acid and their interactions with CD44

J. Mater. Chem. B, 2020, 8,3880-3885
DOI: 10.1039/D0TB00407C, Paper
Sara Amorim, Iva Pashkuleva, Celso A. Reis, Rui L. Reis, Ricardo A. Pires
We developed hyaluronic acid (HA):poly-L-lysine (PLL) layer-by-layer (LbL) constructs whose viscoelastic properties and bioactivity can be finely tuned by using polyanions of different molecular weight and/or crosslinking.
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Platelet membrane-coated nanoparticles for targeted drug delivery and local chemo-photothermal therapy of orthotopic hepatocellular carcinoma

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00735H, Paper
Long Wu, Wei Xie, Hui-Ming Zan, Zhongzhong Liu, Ganggang Wang, Yanfeng Wang, Wei Liu, Wenfei Dong
Specific targeted drug delivery and controllable release of drugs at tumor regions are two of the main challenges for hepatocellular carcinoma (HCC) therapy, particularly post metastasis.
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Boron-based nanosheets for combined cancer photothermal and photodynamic therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00070A, Paper
Yong Kang, Xiaoyuan Ji, Zhengjun Li, Zhiguo Su, Songping Zhang
Tumor phototherapy is of great significance for the expansion and advancement of cancer treatment methods.
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A fiber-shaped neural probe with alterable elastic moduli for direct implantation and stable electronic–brain interfaces

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00508H, Communication
Chengqiang Tang, Songlin Xie, Mengying Wang, Jianyou Feng, Zhengqi Han, Xiaoying Wu, Liyuan Wang, Chuanrui Chen, Jiajia Wang, Liping Jiang, Peining Chen, Xuemei Sun, Huisheng Peng
A fiber-shaped neural probe with alterable elastic moduli allows direct implantation and enables adaptive electronic–tissue interfaces post implantation.
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Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00357C, Paper
Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Lili Zhu, Jianxiang Shi, Wenxue Tang, Wang Ma, Hong Zong, Wei Jiang
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer tissues and inefficient reactive oxygen species (ROS) production.
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Preparation and biological evaluations of collagen-like hierarchical Ti surface with superior osteogenic capabilities

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00799D, Paper
Weiwei Lao, Qiaojie Luo, Yadong Chen, Wei Yao, Jiajia Xu, Lijie Fan, Xiaodong Li
The construction of multiscale Ti surfaces of high osteogenic ability always attracts numerous attentions in oral implantology and implantable biomaterial field. However, so far, the absence of solid understanding of...
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Covalent Organic Framework as Nanocarrier for Synergistic Phototherapy and Immunotherapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00679C, Paper
Ying Zhou, Sainan Liu, Chunling Hu, Lihan Cai, Maolin Pang
As traditional cancer treatment methods, photodynamic therapy (PDT) and photothermal therapy (PTT) can eliminate primary tumor, but can't inhibit tumor extensive metastasis and local recurrence. Herein, in order to prevent...
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The Circadian Clock Gene PER2 Enhances Chemotherapeutic Efficacy in Nasopharyngeal Carcinoma When Combined with a Targeted Nanosystem

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00595A, Paper
Li Hou, Hailiang Li, Haiyan Wang, Dede Ma, Jing Liu, liqiong Ma, Zhihua Wang, Zhihua Yang, Faxuan Wang, Hechun Xia
Treatment failure occurs in more than 40% of advanced nasopharyngeal carcinoma (NPC) patients including local recurrence and distant metastasis due to chemoradioresistance. Circadian clock genes were identified as regulating cancer...
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Ag@S-nitrosothiols core-shell nanoparticles for chemo and photothermal synergistic tumor target therapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00734J, Paper
Xinlin Yang, Tuanwei Liu, Xiao Li, Jinan Wang, Ping Zhang, Xiaoying Huang, Zhide Zhang, Dian-Shun Guo
Along with development of the controlled delivery systems for target therapy, ‘single-strategy’ therapy often fails to achieve the desired performance in real body internal environment. In such case, it is...
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Hydrogels toughened by biominerals as energy-dissipative sacrificial bonds

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00833H, Communication
Kazuki Fukao, Kazuki Tanaka, Ryuji Kiyama, Takayuki Nonoyama, Jian Ping Gong
Inspired by bone tissues, hydrogels toughened by hydroxyapatite (HAp) working as energy-dissipative sacrifical bonds is created. The contribution of dissipated energy from HAp mineral was over 500 % higher than...
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The Praeger handbook of media literacy / Art Silverblatt, editor




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Herding cats : the evolution of the ADF's media embedding program in operational areas / by Jason Logue

Logue, Jason, author




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Community-based multiliteracies & digital media projects : questioning assumptions and exploring realities / edited by Heather M. Pleasants and Dana E. Salter




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Plumer's principles & practice of intravenous therapy / Sharon M. Weinstein

Weinstein, Sharon




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Introducing aromatherapy : beginnner's guide to aromatic essential oils for better health, stamina, relaxation and general well-being / Margrit Bachmann

Bachmann, Margrit




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Drug-drug interaction primer : a compendium of case vignettes for the practicing clinician / by Neil B. Sandson ; contributors, Scott C. Armstrong, Kelly L. Cozza, Jessica R. Oesterheld

Sandson, Neil B., 1965-




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Pharmacology, drug therapy and nursing considerations

Malseed, Roger T