Statement Highlights:  The projected annual cost of preventable hospital-acquired venous thromboembolism (VTE) is $7 billion to $10 billion per year. Most estimates place the US annual incidence of diagnosed VTE in adults at 1 to 2 per 1000 per...

Research Highlights: Young adults using e-cigarettes experienced arterial stiffness and blood vessel damage similar to those who smoke traditional cigarettes. There was no evidence that using e-cigarettes reduced the cardiovascular injury associated...

Research Highlights: The Vein-Chip device, a miniaturized version of a large human vein, allowed scientists to study changes in vein wall cells, blood flow and other functions that lead to deep vein thrombosis in humans. The device focused on venous ...

An intimate account of one young girl’s harrowing experience and miraculous survival.

By Lauren McCauley Common Dreams Even scientists who question findings say ‘we ignore James Hansen at our peril.’ Dr. James Hansen, the former NASA scientist who is widely credited with being one of the first to raise concerns about human-caused … Continue reading →

We kicked things off with an update on Rob's marijuana abstaining, or lack thereof. We then spend a good amount...

The post METAL INJECTION LIVECAST #540 - Eight Iota Ripper with Kenny Hickey of SILVERTOMB / TYPE O NEGATIVE appeared first on Metal Injection.

We kick things off talking about how we spent the holiday break and previewing the bonus Patreon episode coming next...

The post METAL INJECTION LIVECAST #547 - Crab Rangoomba appeared first on Metal Injection.

Andrew Rickmann posted a photo:

The Vulcan at RAF Fairford

The Republican National Committee and President Donald Trump's reelection campaign have doubled their litigation budget to $20 million, Politico reported Thursday. RNC chief of staff Richard Walters told Politico that the GOP is prepared to sue Democrats "into oblivion" by spending "whatever is necessary" to prevail in legal fights against its rivals leading up to the November election.

St-Donat, Bas-St-Laurent, Québec

We show that combining a prediction model (based on neural networks), with a new method of test pooling (better than the original Dorfman method, and better than double-pooling) called 'Grid', we can reduce the number of Covid-19 tests by 73%.

The paper develops a robotic manipulation system to treat the pressing needs for handling a large number of test tubes in clinical examination and replace or reduce human labor. It presents the technical details of the system, which separates and arranges test tubes in racks with the help of 3D vision and artificial intelligence (AI) reasoning/planning. The developed system only requires a person to put a rack with mixed and non-arranged tubes in front of a robot. The robot autonomously performs recognition, reasoning, planning, manipulation, etc., and returns a rack with separated and arranged tubes. The system is simple-to-use, and there are no requests for expert knowledge in robotics. We expect such a system to play an important role in helping managing public health and hope similar systems could be extended to other clinical manipulation like handling mixers and pipettes in the future.

A library of macrocyclic compounds of the formula (I) where part (A) is a bivalent radical, a —(CH2)y— bivalent radical or a covalent bond;where part (B) is a bivalent radical, a —(CH2)z— bivalent radical, or a covalent bond;where part (C) is a bivalent radical, a —(CH2)t— bivalent radical, or a covalent bond; andwhere part (T) is a —Y-L-Z— radical wherein Y is CH2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.

The present invention pertains to an additive combination comprising at least two sterically hindered amines, at least one further stabilizer, a dispersing agent and a plasticizer. The present invention also pertains to a composition comprising an organic material susceptible to degradation by light, oxygen and/or heat, and the additive combination and to the use and the process for stabilizing organic material against degradation by light, oxygen and/or heat by the additive combination.

Non water-soluble polymers with a comb structure and a (meth)acrylic skeleton on which are grafted side chains containing at least one hydrophobic monomer of the styrene or (meth)acrylic ester type on C1 to C4, and at least one hydroxy or methoxy polylakylene glycol monomer. The levels of monomers are such that the polymer is amphiphilic because it is both rich in hydrophobic monomer and polylakylene glycol monomer. These products, used in paper coating dispersions, enable an increase in their Brookfield™ viscosity, a reduction in their ACAV viscosity, and an improvement in their water retention, which makes them particularly well suited for dry extract and/or high deposit speed coatings.

A lubricating oil composition for an internal combustion engine contains: a base oil including a component (A) of a polyalphaolefin having a kinematic viscosity at 100 degrees C. of 5.5 mm2/s or less, a CCS viscosity at −35 degrees C. of 3000 mPa·s or less and a NOACK of 12 mass % or less and a component (B) of a mineral oil having a viscosity index of 120 or more; and polyisobutylene having a mass average molecular weight of 500,000 or more. A content of the composition (A) is 25 mass % or more of a total amount of a lubricating oil.

A lubricating oil composition for an internal combustion engine contains a component (A) of a polyalphaolefin having a kinematic viscosity at 100 degrees C. of 5.5 mm2/s or less, a CCS viscosity at −35 degrees C. of 3000 mPA·s or less and a NOACK of 12 mass % or less, and a component (B) of a mineral oil having a viscosity index of 120 or more. The component (A) is contained at a content of 10 mass % or more of a total amount of the composition.

A process is presented for the increasing the yields of aromatics from reforming a hydrocarbon feedstream. The process includes splitting a naphtha feedstream into a light hydrocarbon stream, and a heavier stream having a relatively rich concentration of naphthenes. The heavy stream is reformed to convert the naphthenes to aromatics and the resulting product stream is further reformed with the light hydrocarbon stream to increase the aromatics yields. The catalyst is passed through the reactors in a sequential manner.

An independently functioning or centrally controlled wall light switch is configured to operate in normal mode and a Jewish holiday mode wherein the state of the light is fixed, regardless of the user's physical manipulation of the light switch. The control system automatically activates holiday mode by combining a geographically determined Jewish religious clock executed by software and hardware that utilizes the current time, date and geographical location of the apparatus in accordance with the Jewish definition of time and laws for calculating numerous religiously significant shifting daily points in time. The control system further incorporates several energy saving and preference modes by utilizing a particular day's calculated religious points in time in conjunction with holiday behavior patterns common to most Jewish families to provide the user with a greatly simplified means of programming an automatically adjusting on/off light timer and dimming overlay functionality during holiday mode.

Systems, mediums, and methods are provided for scheduling input/output requests to a storage system. The input output requests may be received, categorized based on their priority, and scheduled for retrieval from the storage system. Lower priority requests may be divided into smaller sub-requests, and the sub-requests may be scheduled for retrieval only when there are no pending higher priority requests, and/or when higher priority requests are not predicted to arrive for a certain period of time. By servicing the small sub-requests rather than the entire lower priority request, the retrieval of the lower priority request may be paused in the event that a high priority request arrives while the lower priority request is being serviced.

The present invention is directed to a combination reactor system for exothermic reactions comprising a trickle-bed reactor and a shell-and-tube reactor. This combination allows the system to efficiently remove heat while also providing the ability to control both the temperature and/or reaction progression. The trickle-bed reactor removes heat efficiently from the system by utilizing latent heat and does not require the use of a cooling or heating medium. The shell-and-tube reactor is used to further progress the reaction and provides a heat exchanger in order to introduce fluid at the desired temperature in the shell-and-tube reactor. Also, additional reactant or reactants and/or other fluids may be introduced to the shell-and-tube section of the reactor under controlled temperature conditions.

Embodiments provide methods, apparatus, systems, and computer readable media associated with predicting predicates and branch targets during execution of programs using combined branch target and predicate predictions. The predictions may be made using one or more prediction control flow graphs which represent predicates in instruction blocks and branches between blocks in a program. The prediction control flow graphs may be structured as trees such that each node in the graphs is associated with a predicate instruction, and each leaf associated with a branch target which jumps to another block. During execution of a block, a prediction generator may take a control point history and generate a prediction. Following the path suggested by the prediction through the tree, both predicate values and branch targets may be predicted. Other embodiments may be described and claimed.

A method for operating an internal combustion engine in which a speed-based feature of the internal combustion engine, which is correlated with an indicated mean effective pressure of the fuel, is determined during the warm-up of the internal combustion engine and an ideal fuel quantity, which is to be injected into at least one combustion chamber of the internal combustion engine during the warm-up, is ascertained therefrom.

A cleansing composition for cosmetic or household use may include an ampholytic polymer; a crosslinked cationic polymer; a surfactant component selected from the group consisting of anionic surfactants, amphoteric surfactants, cationic surfactants, nonionic surfactants, and zwitterionic surfactants; and an aqueous and/or organic carrier.

A combined table lamp and clock assembly includes a lamp unit and a clock unit. The lamp unit includes a lamp stand base, a lamp stand, and a lamp bulb holder. The lamp stand base has a top side formed with a cavity, and a bottom side adapted to be placed on a table top. The lamp stand extends uprightly from the lamp stand base, and has an upper end portion and a lower end portion that is mounted on the top side of the lamp stand base. The lamp bulb holder is mounted on the upper end portion of the lamp stand, and is adapted for mounting a lamp bulb thereon. The clock unit includes a clock base, an upright clock panel, and a clock mechanism. The clock base is received in the cavity in the top side of the lamp stand base, and is formed with an insert slot therethrough. The upright clock panel has a lower end formed with an insert portion that is inserted removably into the insert slot. The clock mechanism is mounted on the clock panel.

A yo-yo has a recess in one of its faces accommodating a timepiece. The yo-yo is be releasably accommodated in a base, and the base may be worn on a user's person by various means including a wristband in the manner of a wristwatch, a fob or a watch chain in the manner of a pocket watch, a necklace in the manner of a necklace watch, or a holster.

Novel active compound combinations comprising a carboxamide of the general formula (I) (group 1) in which A, R1, R2 and R3 are as defined in the description,and the active compound groups (2) to (23) listed in the description have very good fungicidal properties.

The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description and, secondly, at least one further known active compound from groups (2) to (27) listed in the description, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids and also phytopathogenic fungi.

The present invention relates to compositions, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and to the treated seed.

The present invention relates to compositions, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and to the treated seed.

The present invention relates to compositions, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and to the treated seed.

This invention describes the use of S-abscisic acid (S-ABA) and ethylene producing-agents such as ethephon to synergistically improve red color in grapes and to alter the sensory characteristics of wine.

The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (12) having at least two container receptacles (14a, 14b; 16a, 16) for removably holding containers (18, 20, 22, 24) being in fluid communication with each other, at least one sensor arranged between the container receptacles (14a, 14b; 16a, 16b) and coupled with the closed loop and/or open-loop control unit for detecting a separation layer. Herein, a motor/gear unit (30a, 30b, 32a, 32b) coupled to the closed loop and/or open-loop control unit is associated with each of the container receptacles (14a, 14b; 16a, 16b). Each of the motor/gear units is in operational contact through means (34) with each of the containers (18, 20, 22, 24) supported in the respective container receptacle (14a, 14b; 16a, 16b) such that a transfer and back-transfer of blood components between the containers (18, 20, 22, 24) is initiated.

This invention is related to a pharmaceutical combination that contains a Casein kinase 2 (CK2) peptide inhibitor (termed P15) along with the standard chemotherapeutic drugs used in cancer treatment and which are administered together, separated or sequentially. The chemotherapeutic drugs include cisplatin, taxol, alkaloids from Vinca, 5-fluorouracil, doxorubicin, cyclophosphamide, etoposide, mitomicin C, imatinib, iressa and velcade (vortezomib). The synergism between the P15 peptide and the anticancer drugs achieves an efficient concentration of each cytostatic drug in the combination which is from 10- to 100-fold lower than that for each cytostatic drug alone. The pharmaceutical combination described in this invention exhibits lower toxicity compared to that reported by the anticancer therapeutics and therefore, it represents a crucial advantage for its use in cancer therapy. Furthermore, the sequential administration of this pharmaceutical combination through the pretreatment with the P15 peptide leads to the chemo sensibilization of refractory tumors to the anticancer therapeutics.

Systems and methods are provided for evaluating performance of forecasting models. A plurality of forecasting models may be generated using a set of in-sample data. Two or more forecasting models from the plurality of forecasting models may be selected for use in generating a combined forecast. An ex-ante combined forecast may be generated for an out-of-sample period using the selected two or more forecasting models. The ex-ante combined forecast may then be compared with a set of actual out-of-sample data to evaluate performance of the combined forecast.

The various embodiments disclosed herein relate to combination heart assist systems, methods, and devices that include both an electrical therapy device and a mechanical heart assist device. Various operational modes can be implemented using these embodiments, including a synchronized pacing mode, an internal CPR mode, and an internal workout mode.

A method and system for treating tissue with a combined therapy profile is disclosed. In one exemplary embodiment, ultrasound energy is used to treat numerous depths of tissue within a region of interest and the spatial and temporal properties of the ultrasound energy are varied for more effective treatment. The method and system of the present invention are configured to treat all of the tissue from the surface on down and not spare intervening tissue.

A method for manufacturing a ceramic honeycomb structure includes kneading titania particles, alumina particles and a binder ingredient such that raw material paste including the titania particles, alumina particles and binder ingredient is prepared, forming a body made of the raw material paste and having a honeycomb structure such that the body has the honeycomb structure having multiple through-holes extending in the longitudinal direction of the body and multiple partition portions formed between the through-holes, applying sealant composition including aluminum hydroxide particles, talc particles, kaolin particles, water and organic binder to either end of each through-hole of the body in the longitudinal direction such that the honeycomb structure of the body has each through-hole sealed at one end, and sintering the body made of the raw material paste and having the honeycomb structure sealed by the sealant composition such that a ceramic body having the honeycomb structure is formed.

A unitary elastic mold and cutter combination configured to mold and cut moldable material is disclosed herein. The mold and cutter combination comprises an elastic mold cavity having an elastic bottom wall with an embossed inner surface and an elastic sidewall extending from and unitary with a perimeter of the bottom wall. An elastic cutting blade extends from and is unitary with the sidewall of the mold cavity and is configured to cut moldable material and maintain a substantially consistent perimeter upon cutting. The cutting blade comprises a cutting edge disposed between an inner cutting blade surface and an outer cutting blade surface. The mold and cutter combination may have an elasticity sufficient to release molded material therefrom by hand stretching, wherein the cutting edge, inner cutting blade surface, and the inner surface of the sidewall of the mold cavity are stretched by an amount sufficient to release the molded material.

A combustor apparatus is provided, comprising a mixing arrangement for mixing a carbonaceous fuel with enriched oxygen and a working fluid to form a fuel mixture. A combustion chamber is at least partially defined by a porous perimetric transpiration member, at least partially surrounded by a pressure containment member. The combustion chamber has longitudinally spaced apart inlet and outlet portions. The fuel mixture is received by the inlet portion for combustion within the combustion chamber at a combustion temperature to form a combustion product. The combustion chamber directs the combustion product longitudinally toward the outlet portion. The transpiration member is configured to substantially uniformly direct a transpiration substance therethrough toward the combustion chamber, such that the transpiration substance is directed to flow helically about the perimeter and longitudinally between the inlet and outlet portions, for buffering interaction between the combustion product and the transpiration member. Associated systems are also provided.

A combustion device (1) for a gas turbine includes portions (12) having an inner and an outer wall (13, 14) with an interposed noise absorption plate (15) having a plurality of holes (16). The combustion device (1) further has first passages (17) connecting zones between the inner wall (13) and the plate (15) to the inside of the combustion device (1) and second passages (21) for cooling the inner wall (13). The portions (12) also have an inner layer (22) between the inner wall (13) and the plate (15) defining inner chambers (23), each connected to at least a first passage (17), and an outer layer (24) between the outer wall (14) and the plate (15) defining outer chambers (25) connected to the inner chambers (23) via the holes (16) of the plate (15).

A burner for diluted combustion includes a fuel nozzle for supplying fuel to a combustion chamber, at least one air nozzle for supplying air to the combustion chamber, and at least one oxygen nozzle for supplying oxygen to the combustion chamber. The air nozzle and oxygen nozzle are spatially separated from each other.

Integrated polymeric-ceramic membrane-based oxy-fuel combustor. The combustor includes a polymer membrane structure for receiving air at an input and for delivering oxygen-enriched air at an outlet. An oxygen transport reactor including a ceramic ion transport membrane receives the oxygen-enriched air from the polymer membrane structure to generate oxygen for combustion with a fuel introduced into the oxygen transport reactor.

Method for combustion of a fuel uses an existing air burner (1), including a first supply opening (5) for fuel and a second supply opening (7) for air, which supply openings (5,7) open out into a combustion zone (3). The method is characterised in that a gaseous fuel with an LHV (Lower Heating Value) of less than 7.5 MJ/Nm3 is supplied through the second supply opening (7), in that an oxidant including at least 85 percent by weight oxygen is also supplied to the combustion zone (3) through a supply device for oxidant, and in that the gaseous fuel is caused to be combusted with the oxidant in the combustion zone (3).

The disclosure provides an apparatus and method utilizing fuel reactor comprised of a fuel section, an oxygen carrier section, and a porous divider separating the fuel section and the oxygen carrier section. The porous divider allows fluid communication between the fuel section and the oxygen carrier section while preventing the migration of solids of a particular size. Maintaining particle segregation between the oxygen carrier section and the fuel section during solid fuel gasification and combustion processes allows gases generated in either section to participate in necessary reactions while greatly mitigating issues associated with mixture of the oxygen carrier with char or ash products. The apparatus and method may be utilized with an oxygen uncoupling oxygen carrier such as CuO, Mn3O4, or Co3O4, or utilized with a CO/H2 reducing oxygen carrier such as Fe2O3.

A combustor includes an end cap having an upstream surface axially separated from a downstream surface. A cap shield circumferentially surrounds the upstream and downstream surfaces, tubes extend from the upstream surface through the downstream, and a plenum is inside the end cap. A first baffle extends radially across the plenum toward the cap shield, and a plate extends radially inside the plenum between the first baffle and the upstream surface. A method for supplying fuel to a combustor includes flowing a working fluid through tubes, flowing a fuel into a plenum between upstream and downstream surfaces, radially distributing the fuel along a first baffle, and axially flowing the fuel across a plate that extends radially inside the plenum.

A method of influencing combustion dynamics, including measuring a combustion dynamics parameter, and controlling a diluent flow (26) delivered to a fuel flow (32) upstream of a pilot burner fuel outlet (40) in response to the measured combustion dynamics parameter.

One embodiment of the present invention is an engine. Another embodiment is a unique combustion system. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for engines and combustion systems. Further embodiments, forms, features, aspects, benefits, and advantages of the present application will become apparent from the description and figures provided herewith.

A burner for an exhaust aftertreatment system may include a housing assembly and an ignition device. The housing assembly may include an inner shell surrounded by intermediate and outer shells. The inner shell may at least partially define a combustion chamber. The housing assembly may include an airflow passage having an opening extending through the outer shell. The airflow passage may extend between the outer shell and the intermediate shell as well as between the intermediate shell and the inner shell. The airflow passage may provide fluid communication between the opening and the combustion chamber. The ignition device may be at least partially disposed within the housing assembly and may ignite fuel received from a fuel source and air received from the airflow passage to produce a flame in the combustion chamber. The airflow passage may be in a heat transfer relationship with the flame in the combustion chamber.