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Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves

Interview with Danny Dvir, MD, author of Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves




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Telecare Collaborative Management of Chronic Pain in Primary Care

Interview with Kurt Kroenke, MD, author of Telecare Collaborative Management of Chronic Pain in Primary Care




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Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection

Interview with Mark S. Sulkowski, MD, author of Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection




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Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review

Interview with Karen A. D'Silva, MD, MS, author of Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review




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Perioperative Atrial Fibrillation and the Long-term Risk of Ischemic Stroke

Interview with Hooman Kamel, MD, author of Perioperative Atrial Fibrillation and the Long-term Risk of Ischemic Stroke




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Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults

Interview with Nancy A. Rigotti, MD, author of Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults




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Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial

Interview with Harsha Thirumurthy, PhD, author of Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial




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Collaborative Care for Adolescents With Depression in Primary Care

Interview with Laura P. Richardson, MD, MPH, author of Collaborative Care for Adolescents With Depression in Primary Care




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Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




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Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease

Interview with Andrea S. Gershon, MD, MSc, author of Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease




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Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis

Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis




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Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing

Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing




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Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients

Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients




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Obstetric Quality Indicators and Morbidity

Interview with Elizabeth A Howell, MD, MPP, author of Durability of Benefits of an Outpatient Antimicrobial Stewardship Intervention After Discontinuation of Audit and Feedback




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Climate Change and Global Health Challenges

Interview with Jonathan A. Patz, MD, MPH, author of Climate Change: Challenges and Opportunities for Global Health




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For-Profit Status and Clinical and Economic Outcomes

Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes




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Inpatient STEMI and Treatment and Clinical Outcomes

Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes




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CAD Screening in Patients With Diabetes Mellitus

Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes




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Resident Duty Hour Reforms and Patient Outcomes

Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients




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Effect of Depth and Duration of Cooling on Neonates With HIE

Interview with Seetha Shankaran, MD, author of Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial




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Treatment of Diabetes and Long-term Mortality

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality




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Association Between Bariatric Surgery and Long-term Survival

Interview with David E. Arterburn, MD, MPH and Matthew L. Maciejewski, PhD, authors of Association Between Bariatric Surgery and Long-term Survival




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Breast Cancer Stage at Diagnosis and Survival

Interview with Steven A. Narod, MD, FRCPC, author of Differences in Breast Cancer Stage at Diagnosis and Cancer-Specific Survival by Race and Ethnicity in the United States




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Hematopoietic Stem Cell Transplantation for Multiple Sclerosis

Interview with Richard K. Burt, MD, author of Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis




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MR/Ultrasound Fusion Biopsy for Prostate Cancer

Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer




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Reasons Associated With Readmission After Surgery

Interview with Karl Y. Bilimoria, MD, MS, author of Underlying Reasons Associated With Hospital Readmission Following Surgery in the United States




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Oral Iron Supplementation After Blood Donation

Interview with Joseph E. Kiss, MD, author of Oral Iron Supplementation After Blood Donation




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Varenicline for Smoking Cessation Through Smoking Reduction

Interview with Jon O. Ebbert, MD, MSc, author of Effect of Varenicline on Smoking Cessation Through Smoking Reduction




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Genetic Variant and Vincristine Peripheral Neuropathy in ALL

Interview with William E. Evans, PharmD, author of Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia




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Natural History of Benign Thyroid Nodules

Interview with Sebastiano Filetti, MD, author of The Natural History of Benign Thyroid Nodules




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Outcomes After Transcatheter Aortic Valve Replacement

Interview with David R. Holmes Jr, MD, author of Clinical Outcomes at 1 Year Following Transcatheter Aortic Valve Replacement




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Maternal Diabetes and Autism in Offspring

Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring




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Autism Occurrence by MMR Vaccine Status Among US Children

Interview with Anjali Jain, MD, author of Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism




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Oral Insulin and Immune Responses in Children at Risk for Diabetes

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial




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ED-Initiated Treatment for Opioid Dependence

Interview with Gail D'Onofrio, MD, MS, author of Emergency Department-Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial




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Oral Steroids for Acute Sciatica Due to Herniated Lumbar Disk

Interview with Harley Goldberg, DO, author of Oral Steroids for Acute Radiculopathy Due to a Herniated Lumbar Disk: A Randomized Clinical Trial




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Antidepressant Use Late in Pregnancy and Effects on Newborn

Interview with Krista F. Huybrechts, MS, PhD, author of Antidepressant Use Late in Pregnancy and Risk of Persistent Pulmonary Hypertension of the Newborn




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Why the Americans With Disabilities Act Matters for Genetics

Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics




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Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery




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ICD Use Among Medicare Patients After Acute MI

Interview with Tracy Y. Wang, MD, MHS, MSc, author of Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction




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Medical Marijuana for Treatment of Chronic Pain and Other Problems

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?




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Duration of Oral Anticoagulation After PE

Interview with Francis Couturaud, MD, PhD, author of Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial




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Maternal Malignancy and Noninvasive Prenatal Testing

Interview with Diana W. Bianchi, MD, author of Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies




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Cost-effectiveness of Varying 10-Year Risk Statin Treatment Thresholds

Interview with Thomas A. Gaziano, MD, MSc, author of Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease




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Managing Atrial Fibrillation

Edward H. Livingston, MD discusses atrial fibrillation with Eric N. Prystowsky, MD, author of Treatment of Atrial Fibrillation. This review article reports that therapy for atrial fibrillation should include rate control for all patients, but maintenance of sinus rhythm with drugs or catheter ablation should be considered on an individual patient basis. Also on the program is a conversation about new technologies to facilitate screening for atrial fibrillation with Leslie Saxon, MD.




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Mortality, Hospitalizations, and Expenditures for the Medicare Population

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013




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Donald M. Berwick Reflects on Medicare at 50

Medicare at 50: Reflections From Former CMS Administrator Donald M. Berwick, MD




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Medicare and Medicaid at 50 Years

Interview with Drew Altman, PhD and William Frist, MD, authors of Medicare and Medicaid at 50 Years: Perspectives of Beneficiaries, Health Care Professionals and Institutions, and Policy Makers




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Posttraumatic Stress Disorder

Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress Disorder? The article by Dr Steenkamp reports that many military personnel and veterans with posttraumatic stress disorder achieve clinically meaningful improvement with use of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure.
 The Rational Clinical Examination Systematic Review by Dr Spoont examines the utility of self-report screening instruments for posttraumatic stress disorder among primary care and high-risk populations.




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Testosterone and Atherosclerosis in Older Men

Interview with Shalender Bhasin, MBBS, author of Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial