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Effects of Exercise Training on Depressive Symptoms in Patients With Chronic Heart Failure: The HF-ACTION Randomized Trial

Interview with James A. Blumenthal, PhD, author of Effects of Exercise Training on Depressive Symptoms in Patients With Chronic Heart Failure: The HF-ACTION Randomized Trial




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The State of the World's Refugees: Adapting Health Responses to Urban Environments

Interview with Paul Spiegel, MD, author of The State of the World's Refugees: Adapting Health Responses to Urban Environments




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Effect of Biolimus-Eluting Stents With Biodegradable Polymer vs Bare-Metal Stents on Cardiovascular Events Among Patients With Acute Myocardial Infarction: The COMFORTABLE AMI Randomized Trial

Interview with Stephan Windecker, MD, author of Effect of Biolimus-Eluting Stents With Biodegradable Polymer vs Bare-Metal Stents on Cardiovascular Events Among Patients With Acute Myocardial Infarction: The COMFORTABLE AMI Randomized Trial




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Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Biologic Therapy: A Meta-analysis

Interview with Maria E Suarez-Almazor, MD, PhD, author of Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Biologic Therapy: A Meta-analysis




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Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma: The BASALT Randomized Controlled Trial

Interview with William J. Calhoun, MD, author of Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma: The BASALT Randomized Controlled Trial




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The Attending Physician on the Wards: Finding a New Homeostasis

Special interview by Howard Bauchner, MD, Editor in Chief of JAMA, with Robert M. Wachter, MD, and Abraham Verghese, MD, MACP, authors of The Attending Physician on the Wards: Finding a New Homeostasis




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The Next Generation of Obesity Research: No Time to Waste

Interview with Griffin P. Rodgers, MD, author of The Next Generation of Obesity Research: No Time to Waste




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Total Knee Arthroplasty Volume, Utilization, and Outcomes Among Medicare Beneficiaries, 1991-2010

Interview with Peter Cram, MD, MBA, author of Total Knee Arthroplasty Volume, Utilization, and Outcomes Among Medicare Beneficiaries, 1991-2010




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Effect of Vitamin D3 Supplementation on Upper Respiratory Tract Infections in Healthy Adults: The VIDARIS Randomized Controlled Trial

Interview with Carlos A. Camargo, MD, author of Effect of Vitamin D3 Supplementation on Upper Respiratory Tract Infections in Healthy Adults: The VIDARIS Randomized Controlled Trial




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Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group

Interview with Matthew K. Wynia, MD, MPH, author of Challenges at the Intersection of Team-Based and Patient-Centered Health Care: Insights From an IOM Working Group




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Association of Public Reporting for Percutaneous Coronary Intervention With Utilization and Outcomes Among Medicare Beneficiaries With Acute Myocardial Infarction

Interview with Karen E. Joynt, MD, MPH, author of Association of Public Reporting for Percutaneous Coronary Intervention With Utilization and Outcomes Among Medicare Beneficiaries With Acute Myocardial Infarction




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The Problem With Peripherally Inserted Central Catheters

Interview with Vineet Chopra, MD, MSc and Scott A Flanders, MD, authors of The Problem With Peripherally Inserted Central Catheters




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Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010

Interview with Tarak K. Trivedi, BS, author of Hospitalizations and Mortality Associated With Norovirus Outbreaks in Nursing Homes, 2009-2010




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Association of Online Patient Access to Clinicians and Medical Records With Use of Clinical Services

Interview with Ted E. Palen, MD, PhD, MSPH, author of Association of Online Patient Access to Clinicians and Medical Records With Use of Clinical Services




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Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol

Interview with Sangeeta Mehta, MD, author of Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol




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Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010

Interview with Lara K. Misegades, PhD, MS, author of Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010




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Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008

Interview with David S. Friedman, MD, MPH, PhD, author of Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008




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Association Between World Trade Center Exposure and Excess Cancer Risk

Interview with Steven D. Stellman, PhD, MPH, author of Association Between World Trade Center Exposure and Excess Cancer Risk




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Association of Clopidogrel Pretreatment With Mortality, Cardiovascular Events, and Major Bleeding Among Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis

Interview with Gilles Montalescot, MD, PhD, author of Association of Clopidogrel Pretreatment With Mortality, Cardiovascular Events, and Major Bleeding Among Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis




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Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011

Interview with Bryant J. Webber, MD, author of Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011




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Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis

Interview with Katherine M. Flegal, PhD, author of Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis




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How and Why US Health Care Differs From That in Other OECD Countries

Interview with Victor R. Fuchs, PhD, author of How and Why US Health Care Differs From That in Other OECD Countries




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Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial

Interview with Timothy McAlindon, DM, MPH, author of Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis: A Randomized Controlled Trial




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Association Between Medicare Advantage Plan Star Ratings and Enrollment

Interview with William H. Shrank, MD, MSHS, author of Association Between Medicare Advantage Plan Star Ratings and Enrollment




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Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia

Interview with Harlan M. Krumholz, MD, SM, author of Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia




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Change in End-of-Life Care for Medicare Beneficiaries: Site of Death, Place of Care, and Health Care Transitions in 2000, 2005, and 2009

Interview with Joan M. Teno, MD, MS, author of Change in End-of-Life Care for Medicare Beneficiaries: Site of Death, Place of Care, and Health Care Transitions in 2000, 2005, and 2009




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Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children

Interview with Pål Surén, author of Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children




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Bariatric Surgery Complications Before vs After Implementation of a National Policy Restricting Coverage to Centers of Excellence

Interview with Justin B. Dimick, MD, MPH, author of Bariatric Surgery Complications Before vs After Implementation of a National Policy Restricting Coverage to Centers of Excellence




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Association Between the Initiation of Anti-Tumor Necrosis Factor Therapy and the Risk of Herpes Zoster

Interview with Kevin L Winthrop, MD, MPH, author of Association Between the Initiation of Anti-Tumor Necrosis Factor Therapy and the Risk of Herpes Zoster




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Association of Smoking Cessation and Weight Change With Cardiovascular Disease Among People With and Without Diabetes

Interview with James B. Meigs, MD, MPH, author of Association of Smoking Cessation and Weight Change With Cardiovascular Disease Among People With and Without Diabetes




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Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial

Interview with Gervasio A. Lamas, MD, author of Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial




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Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial

Interview with Ellen M. Lavoie Smith, PhD, author of Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial




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Melatonin Secretion and the Incidence of Type 2 Diabetes

Interview with Ciaran J. McMullan, MD, author of Melatonin Secretion and the Incidence of Type 2 Diabetes




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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Interview with Richard Mayeux, MD, MSc, author of Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism




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Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants: A Randomized Trial

Interview with Hope Weiler, RD, PhD, author of Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants: A Randomized Trial




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Elective Cesarean Delivery on Maternal Request

Interview with Jeffrey Ecker, MD, author of Elective Cesarean Delivery on Maternal Request




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Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

Interview with Emily Y. Chew, MD, author of Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial




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Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial

Interview with Jonas Rutishauser, MD, author of Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial




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Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial

Interview with Jeffrey S. Gerber, MD, PhD, author of Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial




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Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate

Interview with Anurag N. Malani, MD, author of Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate




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Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic Stroke

Interview with Jeffrey L. Saver, MD, author of Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic Stroke




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Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer

Interview with Brent K. Hollenbeck, MD, MS, author of Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer




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The Paradox of Disease Prevention: Celebrated in Principle, Resisted in Practice

Interview with Harvey V. Fineberg, MD, PhD, author of The Paradox of Disease Prevention: Celebrated in Principle, Resisted in Practice




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Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries

Interview with Daniel D. Matlock, MD, MPH, author of Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries




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The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors

Interview with Christopher J. L. Murray, MD, DPhil, author of The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors




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Association Between Duration of Overall and Abdominal Obesity Beginning in Young Adulthood and Coronary Artery Calcification in Middle Age

Interview with Jared P. Reis, PhD, author of Association Between Duration of Overall and Abdominal Obesity Beginning in Young Adulthood and Coronary Artery Calcification in Middle Age




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Risk Factors Associated With Suicide in Current and Former US Military Personnel

Interview with Cynthia A. LeardMann, MPH, author of Risk Factors Associated With Suicide in Current and Former US Military Personnel