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Correction: Matrix-mediated distribution of 4-hydroxy-2-hexanal (nonenal) during deep-frying of chicken breast and potato sticks in vegetable oil

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Food Funct., 2020, 11,3750-3750
DOI: 10.1039/D0FO90018D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukai Ma, Guoqin Liu, Weiwei Cheng, Xinqi Liu, Huifan Liu, Qin Wang
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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

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Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
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Gut microbiota mediate the protective effects on endometritis induced by Staphylococcus aureus in mice

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Food Funct., 2020, 11,3695-3705
DOI: 10.1039/C9FO02963J, Paper
Xiaoyu Hu, Ruiying Mu, Mingyue Xu, Xin Yuan, Peng Jiang, Jian Guo, Yongguo Cao, Naisheng Zhang, Yunhe Fu
Endometritis, the inflammation of the endometrial lining caused by bacterial pathogens, is associated with reproductive failure.
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Inflammation and cardiovascular disease: are marine phospholipids the answer?

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Food Funct., 2020, 11,2861-2885
DOI: 10.1039/C9FO01742A, Review Article
Ronan Lordan, Shane Redfern, Alexandros Tsoupras, Ioannis Zabetakis
This review presents the latest research on the cardioprotective effects of n-3 fatty acids (FA) and n-3 FA bound to polar lipids (PL). Overall, n-3 PL may have enhanced bioavailability and potentially bioactivity versus free FA and ester forms of n-3 FA.
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Potential neurotoxicity of 5-hydroxymethylfurfural and its oligomers: widespread substances in carbohydrate-containing foods

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02526J, Paper
Cheng Wang, Zhenru Liu, Tian Hu, Youjia Li, Rui Liu, Junjie Zhang, Huaizhen He
5-Hydroxymethylfurfural (5-HMF) and its acid-catalyzed oligomers can inhibit nerve cell proliferation and induce neurological deficits at near or below the reported 24 h dietary intake of 5-HMF in humans.
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Alleviating effects of noni fruit polysaccharide on hepatic oxidative stress and inflammation in rats under a high-fat diet and its possible mechanisms

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Food Funct., 2020, 11,2953-2968
DOI: 10.1039/D0FO00178C, Paper
Xiaobing Yang, Wenjing Mo, Chuanjin Zheng, Wenzhi Li, Jian Tang, Xiaoyong Wu
Non-alcoholic fatty liver disease is associated with gut microbiota, oxidative stress, and inflammation.
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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

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Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
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Enzymatic hydrolysis of insect Alphitobius diaperinus towards the development of bioactive peptide hydrolysates

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Food Funct., 2020, 11,3539-3548
DOI: 10.1039/D0FO00188K, Paper
Pedro Sousa, Sandra Borges, Manuela Pintado
Edible insects are a promising protein source for the future generation, due to their nutritional composition, sustainability and low environmental impact.
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A rapid protocol to distinguish between Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium based on the characteristic fingerprint and UHPLC-Q-TOF MS methods

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Food Funct., 2020, 11,3719-3729
DOI: 10.1039/D0FO00082E, Paper
Liqiang Shi, Rongjin Wang, Tianshu Liu, Jiajie Wu, Hongxu Zhang, Zhiqiang Liu, Shu Liu, Zhongying Liu
Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium were successfully distinguished by the characteristic fingerprint and UHPLC-Q-TOF MS methods.
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Antihypertensive effects of Trichiurus lepturus myosin hydrolysate in spontaneously hypertensive rats

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Food Funct., 2020, 11,3645-3656
DOI: 10.1039/C9FO02687H, Paper
Weiqing Fu, Peixin Wang, Hongqiang Wu, Zhigang Zhang, Hongliang Zeng, Yi Zhang, Baodong Zheng, Jiamiao Hu
In this study, the blood pressure-lowering effects of Trichiurus lepturus myosin hydrolysate (TMH) and its possible mechanism were investigated in spontaneously hypertensive rats (SHRs).
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A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice

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Food Funct., 2020, 11,2943-2952
DOI: 10.1039/D0FO00206B, Paper
Open Access
Ana Lemus-Conejo, Elena Grao-Cruces, Rocio Toscano, Lourdes M. Varela, Carmen Claro, Justo Pedroche, Francisco Millan, Maria C. Millan-Linares, Sergio Montserrat-de la Paz
A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice.
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Kaempferol modulates TCDD- and t-BHQ-induced drug-metabolizing enzymes and luteolin enhances this effect

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Food Funct., 2020, 11,3668-3680
DOI: 10.1039/C9FO02951F, Paper
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Co-treatment with kaempferol and luteolin inhibits AhR- and Nrf2-induced expression of drug-metabolizing enzymes.
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Correction: Efficacy of proprietary Lactobacillus casei for anti-tuberculosis associated gastrointestinal adverse reactions in adult patients: a randomized, open-label, dose–response trial

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Food Funct., 2020, 11,3751-3751
DOI: 10.1039/D0FO90017F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Song Lin, Shanliang Zhao, Jiahong Liu, Jianwen Zhang, Chao Zhang, Haibo Hao, Yuxia Sun, Jing Cai, Yang Yang, Yan Ma, Yuanyuan Li, Jinyu Wang, Aiguo Ma
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Protective effect of ferulic acid on STZ-induced diabetic nephropathy in rats

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Food Funct., 2020, 11,3706-3718
DOI: 10.1039/C9FO02398D, Paper
Min-you Qi, Xu-tao Wang, Hui-lin Xu, Zhang-liang Yang, Yin Cheng, Bin Zhou
Ferulic acid protects against diabetic nephropathy in STZ-induced rats by attenuating oxidative stress, inflammation, fibrosis and podocyte injury.
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The purification, structural characterization and antidiabetic activity of a polysaccharide from Anoectochilus roxburghii

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Food Funct., 2020, 11,3730-3740
DOI: 10.1039/C9FO00860H, Paper
Yuntao Liu, Tingting Tang, Songqi Duan, Cheng Li, Qinlu Lin, Hejun Wu, Aiping Liu, Bin Hu, Dingtao Wu, Suqing Li, Li Shen, Wenjuan Wu
Anoectochilus roxburghii, a traditional Chinese medicinal herb, has been widely used for treating numerous chronic diseases.
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tert-Butyl-p-benzoquinone induces autophagy by inhibiting the Akt/mTOR signaling pathway in RAW 264.7 cells

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00281J, Paper
Xianghe Meng, Chaosheng Xia, Qin Ye, Xiaohua Nie
Autophagy mediate by p53/Akt/mTOR signaling was linked to overproduction of ROS by tert-butyl-p-benzoquinone.
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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
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Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00732C, Paper
Hao Zhang, Yanan Chen, Yueping Chen, Peilu Jia, Shuli Ji, Jianxiong Xu, Yue Li, Tian Wang
Pterostilbene is more effective than resveratrol in alleviating liver injury, facilitating redox status, and improving mitochondrial function of piglets.
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Bergaptol from blossoms of Citrus aurantium L. var. amara Engl inhibits LPS-induced inflammatory responses and ox-LDL-induced lipid deposition

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO00255C, Paper
Chun-Yan Shen, Tian-Xing Wang, Jian-Guo Jiang, Chun-Ling Huang, Wei Zhu
Aberrant activation of inflammation and excess accumulation of lipids play pivotal roles in atherosclerosis (AS) progression. Constituents from Citrus aurantium Linn variant amara Engl (CAVA) were effectively investigated for their...
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Targets and Underlying Mechanisms for Sedative and Hypnotic Activities of Saponins from Semen Ziziphus jujube

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00098A, Paper
Chun-Yan Shen, Lin Wan, Jing-Jing Zhu, Jian-Guo Jiang
Semen Ziziphus jujube (SZJ) has been widely consumed as edible resources in China to treat insomnia disorders. However, the underlying mechanisms and potential therapeutic targets remained obscure. SZJ-I and SZJ-II...
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Tomato seed oil attenuates hyperlipidemia and modulates gut microbiota in C57BL/6J mice

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00133C, Paper
Wen-Sen He, Lingling Li, Jiaxin Rui, Junjie Li, Yuying Sun, Dandan Cui, Bin Xu
TSO can significantly improve fatty acid metabolism and cholesterol metabolism, thereby inhibiting obesity and hypercholesterolemia. TSO can favorably modulate the gut microbiota.
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Red ginseng protects against cisplatin-induced intestinal toxicity by inhibiting apoptosis and autophagy via the PI3K/AKT and MAPK signaling pathways

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00469C, Paper
Jun-jie Zhang, Jian-qiang Wang, Xing-yue Xu, Jia-yu Yang, Zi Wang, Shuang Jiang, Ying-ping Wang, Jing Zhang, Rui Zhang, Wei Li
Although growing evidence has shown that ginseng (Panax ginseng C.A. Meyer.) exerts strong protective and preventive effects on cisplatin-induced side effects, the ameliorative effects of ginseng on intestinal damage caused by cisplatin are unknown to date.
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Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO03017D, Paper
Ruiqiu Zhao, Yang Ji, Xin Chen, Anxiang Su, Gaoxing Ma, Guitang Chen, Qiuhui Hu, Liyan Zhao
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice.
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Effects of polysaccharides from wild morels on immune response and gut microbiota composition in non-treated and cyclophosphamide-treated mice

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00597E, Paper
Wenyan Huo, Zhengping Feng, Suying Hu, Langjun Cui, Ting Qiao, Lu Dai, Peng Qi, Liguang Zhang, Yu Liu, Junzhi Li
Polysaccharides from wild morels alter gut microbiota, increase the production of SCFAs and promote the proliferation of lymphocytes in mice.
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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
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Cytoprotective effects of a proprietary red maple leaf extract and its major polyphenol, ginnalin A, against hydrogen peroxide and methylglyoxal induced oxidative stress in human keratinocytes

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00359J, Paper
Chang Liu, Hao Guo, Joel A. Dain, Yinsheng Wan, Xing-Hua Gao, Hong-Duo Chen, Navindra P. Seeram, Hang Ma
Maplifa™ (a proprietary red maple leaves extract) and its major polyphenol, ginnalin A, exert skin protective effects against oxidative stress.
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Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02854D, Paper
Mohsen Zareian, Ehsan Oskoueian, Marjan Majdinasab, Bita Forghani
The present study aimed to develop a fermented food (idli) with enhanced γ-aminobutyric acid (GABA) and angiotensin I-converting enzyme (ACE) inhibitory properties using a GABA-producing fungus.
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Physicochemical and antibacterial properties of fabricated ovalbumin-carvacrol gel nanoparticles

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00755B, Paper
Shengqi Rao, Guang-wei Xu, Huawei Zeng, Xiang-feng Zheng, Qin Hu, Qi-Yan Wang, Zhenquan Yang, Xin'An Jiao
The applications of carvacrol are limited due to its poor stability, water solubility, and high volatility; however, ovalbumin can be used to encapsulate hydrophobic molecules, improve their aqueous solubility, and...
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Lactic acid bacteria alleviates polycystic ovarian syndrome by regulating sex hormone related gut microbiota

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02554E, Paper
Yufeng He, Qianqian Wang, Xiu Li, Gang Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Polycystic ovarian syndrome (PCOS) is a common endocrine disease across the world. Because gut microbiota play a key role in the pathogenesis of PCOS, probiotics may alleviate PCOS symptoms through...
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The cognitive effects of an acute wild blueberry intervention on 7 – 10 year olds using extended memory and executive function task batteries.

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02284H, Paper
Adrian Robert Whyte, Daniel J Lamport, Graham Schafer, Claire M. Williams
Evidence for the health benefits of blueberries is well documented. In particular memory and executive function benefits have both been found for children aged 7 – 10 in the 6...
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Enzyme reaction-guided identification of active components from the flowers of Sophora japonica var. violacea

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00625D, Paper
Yunci Zhang, Dongyu Gu, Shuai He, Jing Meng, Jifeng Wang, Yunxiao Wang, Yi Wang, Jing Tian, Yi Yang
The flower of S. japonica is a favorite food and used as traditional medicine.
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Jiaogulan tea (Gpostemma pentaphyllum) potentiates the antidiabetic effect of white tea via the AMPK and PI3K pathways in C57BL/6 mice

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00395F, Paper
Xiaoyan Xia, Jing Xu, Xude Wang, Hua Wang, Zhenchuan Lin, Keping Shao, LinLin Fang, Chenning Zhang, Yuqing Zhao
The use of plant-based beverages to interfere with the onset of diabetes may be a promising approach towards type 2 diabetes mellitus (T2DM).
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The Ameliorative Effect of Lactobacillus plantarum-12 on DSS-induced murine colitis

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00007H, Paper
MengYing Sun, YuJun Liu, Yinglong Song, Yuan Gao, Fujunzhu Zhao, Yanghe Luo, Fang Qian, Guangqing Mu, Yanfeng Tuo
Some lactobacilli strains can exert beneficial effects on host when ingested in an adequate dose, such as immunoregulation and anti-inflammatory activities. In this study, the survival abilities in simulated gastrointestinal...
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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00319K, Paper
Cezara Zagrean-Tuza, Augustin C Moţ, Tomasz Chmiel, Attila Bende, Ioan Turcu
Quercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its...
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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
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Cerebral effect of optimized Allium sativum oil-loaded chitosan nanorods: GC-MS analysis and in-vitro/in-vivo evaluation

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02911G, Paper
Rabab Kamel, Abeer Salama, Nesma Mohammed, Nermine Shaffie
The chemical constituents of Allium sativum (Garlic) oil were investigated using GC/Ms technique after silylation, and revealed the presence of several fatty acids and their esters. The most dominant was...
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Kinetic profile and urinary excretion of phenyl-γ-valerolactones upon consumption of cranberry: a dose-response relationship

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00806K, Paper
Claudia Favari, Pedro Mena, Claudio Curti, Geoffrey Istas, Christian Heiss , Daniele Del Rio, Ana Rodriguez-Mateos
Cranberries are a rich source of poly(phenols), mainly monomeric and oligomeric flavan-3-ols. However, information on the appearance of their main circulating microbial metabolites, namely phenyl-γ-valerolactones and phenylvaleric acid, is lacking...
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Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00428F, Paper
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Polygonatum sibiricum is a medicinal and homologous plant grown in China. The saponin in Polygonatum sibiricum has shown its good hypoglycemic performance, and it can be developed as functional foods and drugs with hypoglycemic effect.
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Unveiling the bioactivity potential of Allium triquetrum L. lipophilic fraction: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00769B, Paper
Samia Rabah, Kahina Kouachi, Patricia Ramos, Ana T. P. C. Gomes, Adelaide Almeida, Hayate Haddadi-Guemghar, Khodir Madani, Armando Silvestre, Sónia A. O. Santos
The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time, by GC-MS. Sixty-two compounds were firstly identified in A. triquetrum L. Fatty acids...
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Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
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Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00734J, Paper
Fernando Rivero Pino, Raúl Pérez Gálvez, F. Javier Espejo Carpio, Emilia M. Guadix
Tenebrio molitor hydrolysates produced with commercial proteases showed improved ACE inhibitory and antioxidant properties. This source could be employed as functional ingredient in food preparations.
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Mechanisms for Lactobacillus rhamnosus treatment of intestinal infection by drug-resistant Escherichia coli

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00128G, Paper
Na Li, Bing Pang, Junjun Li, Guanwen Liu, Xiaoguang Xu, Dongyan Shao, Chunmei Jiang, Baowei Yang, Junling Shi
Reducing the viability of pathogens may also play an important role for the therapeutic effects of Lactobacillus rhamnosus SHA113 against multiple-drug-resistant E. coli, as well as influencing on the intestinal integrity and functions of animals.
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Dietary supplementation of L-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00019A, Paper
Hao Zhang, Yi Ma, Mengzhi Wang, Mabrouk Elsabagh, Juan J. Loor, Hongrong Wang
The work aimed at investigating the effects of N-carbamylglutamate (NCG) or L-arginine (Arg) supplementation on the duodenal mitophagy, inflammation, and barrier function in suckling lambs suffering from intrauterine-growth-retardation (IUGR).
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Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
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Deciphering calcium-binding behaviors of casein phosphopeptides by experimental approaches and molecular simulation

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00844C, Paper
Minna Luo, Jie Xiao, Shengwei Sun, Fengchao Cui, Wei Li, Guo Liu, Yunqi Li, Yong Cao
Although specific groups in casein phosphopeptides (CPPs) have been identified to be essential for the calcium-binding capacity, how calcium binds with CPPs remains unclear. In the present study, experimental methods...
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The milk macromolecular peptide: preparation and evaluation of antihypertensive activity in rats

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00151A, Paper
Pengfei Cui, Xue Yang, Yunliang Li, Qiufang Liang, Yucheng Wang, Feng Lu, John Owusu, Shanfen Huang, Xiaofeng Ren, Haile Ma
In order to avoid the discomfort of digesting milk protein and make full use of the gastrointestinal digestive function, a milk macromolecular peptide was prepared with ACE inhibitory activity after gastrointestinal digestion as the index.
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Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02521A, Paper
Huahong Yang, Cong Hua, Xiaolin Yang, Xiaoye Fan, Hongyu Song, Liping Peng, Xinxin Ci
Schematic model of the protective effects by Pts on LPS-induced lung fibrosis.
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Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00711K, Paper
J. Q. Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Yu-Jia Zhang, Chan-Min Liu
Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibited potential renoprotective properties. Here we examined the protective effects of GAS against carbon tetrachloride (CCl4)-induced kidney inflammation and...
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Unsaturated alginate oligosaccharides attenuated obesity-related metabolic abnormalities by modulating gut microbiota in high-fat-diet mice

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02857A, Paper
Shangyong Li, Linna Wang, Bo Liu, Ningning He
Gut microbiota plays an important role in the high-fat diet (HFD)-induced obesity and related metabolic syndrome (MetS). Our previous study has demonstrated that unsaturated alginate oligosaccharides (UAOS) degraded by alginate...
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