z Systems and methods for subsurface oil recovery optimization By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT Systems and methods for subsurface secondary and/or tertiary oil recovery optimization based on either a short term, medium term or long term optimization analysis of selected zones, wells, patterns/clusters and/or fields. Full Article
z Prioritization of three dimensional dental elements By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The present disclosure includes methods, systems, and devices for prioritization of three dimensional dental elements. One method for prioritizing three dimensional dental elements includes receiving a virtual initial dental data set (IDDS) of teeth having spatial information regarding the positions of a number of teeth in the virtual IDDS with respect to each other for presentation of the teeth in a virtual three dimensional space to be viewed on a user interface, setting prioritization values of a number of elements of one or more of the number of teeth, and prioritizing the number of elements to be selected by a user based upon their prioritization values. Full Article
z Systems and methods for identifying personalized vascular implants from patient-specific anatomic data By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Embodiments include methods of identifying a personalized cardiovascular device based on patient-specific geometrical information, the method comprising acquiring an anatomical model of at least part of the patient's vascular system; performing, using a processor, one or more of geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis on the anatomical model; and identifying, using the processor, a personalized cardiovascular device for the patient, based on results of one or more of the geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis of anatomical model. Full Article
z Systems and methods for identifying personalized vascular implants from patient-specific anatomic data By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Embodiments include methods of identifying a personalized cardiovascular device based on patient-specific geometrical information, the method comprising: generating a patient specific model of at least a portion of a patient's vasculature from image data of the patient's vasculature and one or more measured or estimated physiological or phenotypic parameters of the patient; determining pathology characteristics from cardiovascular geometry of the patient specific model; defining an objective function for a device based on design considerations and one or more estimates of hemodynamic and mechanical characteristics; optimizing the objective function, by simulating at least one change in devices and evaluating the objective function using fluid dynamic or structural mechanic analysis; and using the optimized objective function to either (i) select a device from a set of available devices or (ii) manufacture a desired device. Full Article
z Leveraging transactional memory hardware to accelerate virtualization and emulation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Various technologies and techniques are disclosed for using transactional memory hardware to accelerate virtualization or emulation. State isolation can be facilitated by providing isolated private state on transactional memory hardware and storing the stack of a host that is performing an emulation in the isolated private state. Memory accesses performed by a central processing unit can be monitored by software to detect that a guest being emulated has made a self modification to its own code sequence. Transactional memory hardware can be used to facilitate dispatch table updates in multithreaded environments by taking advantage of the atomic commit feature. An emulator is provided that uses a dispatch table stored in main memory to convert a guest program counter into a host program counter. The dispatch table is accessed to see if the dispatch table contains a particular host program counter for a particular guest program counter. Full Article
z Fabrication of zeolite composite film By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A fabrication of a zeolite composite film includes mixing a composition of water, aluminum isopropoxide, TMAOH, and TEOS according to a set ratio, followed by stirring and heating to obtain a mixture; performing a centrifugation on the mixture to obtain an upper layer suspension; preparing a mesoporous particle suspension that includes a plurality of mesoporous particles, and each mesoporous particle includes a plurality of templating agents; vaporizing a mixture suspension formed from both the upper layer suspension and the mesoporous particle suspension to form a plurality of vaporized droplets; depositing the vaporized droplets on a heated substrate while removing the templating agents to form the zeolite composite film with a plurality of macroporous, mesoporous and microporous structures. Full Article
z Skull-focused RF-based stimulation apparatus, system and method for treating patients with Alzheimer's disease or other dementia By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The portable, wearable, proximal Alzheimer's disease treatment invention is based upon creating an RF field of particular frequencies and intensities that are applied to the patient's head. To accomplish the aforementioned disease treatment functionality, a system was invented comprising a network of antennas connected to an RF generator via a feedline connector. The invention also provides methods for using measurements to monitor and manage the effectiveness of an ongoing disease treatment regimen, and databases which contain information about measurements, variables, and their relationships to clinical outcome. Full Article
z Method and apparatus for quantitative nerve localization By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method for localizing a needle to a nerve, the method comprising: using the needle to electrically stimulate the nerve, with a known current intensity, so as to evoke a nerve response;detecting the nerve response;analyzing the detected nerve response so as to identify at least one attribute of the same; andconfirming that the needle is in the immediate proximity of the nerve based upon known current intensity and at least one identified attribute of the detected nerve response. Full Article
z Minimizing interference between charging and telemetry coils in an implantable medical device By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An improved implantable pulse generator (IPG) containing improved telemetry circuitry is disclosed. The IPG includes charging and telemetry coils within the IPG case, which increases their mutual inductance and potential to interfere with each other; particularly problematic is interference to the telemetry coil caused by the charging coil. To combat this, improved telemetry circuitry includes decoupling circuitry for decoupling the charging coil during periods of telemetry between the IPG and an external controller. Such decoupling circuitry can comprise use of pre-existing LSK circuitry during telemetry, or new discrete circuitry dedicated to decoupling. The decoupling circuitry is designed to prevent or at least reduce induced current flowing through the charging coil during data telemetry. The decoupling circuitry can be controlled by the microcontroller in the IPG, or can automatically decouple the charging coil at appropriate times to mitigate an induced current without instruction from the microcontroller. Full Article
z Systems, devices, and methods for directly energizing water molecule composition By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT Systems, devices, and methods for generating energized water molecules and administering same to a human or other biological subject. The system includes a humidifying apparatus, and excitation apparatus, and a control system. The system may further include a fluid management system to assist in the delivery of energized water molecules. Full Article
z Nozzle separating structure of oral irrigator By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A structure for separating a discharge nozzle of an oral irrigator includes a first discharge path formed in one side of the irrigator body, a water pressure control lever rotatably arranged above the first discharge path and having a second discharge path in the other side of the irrigator body, a release button section provided on an upper portion of the water pressure control lever and into which the discharge nozzle is inserted and engaged, and configured, when pushed, to be bent so as to release the engaged discharge nozzle, and a locking section provided in the release button section and water pressure control lever to control a pushing operation of the release button section depending upon whether the first discharge path is open or blocked. Full Article
z Method and apparatus for forming unit portions of frozen food materials By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT An apparatus for forming pressed food products can utilize up to 98% chicken breast meat in high profit margin products. Breast meat is marinated and then extruded into a slab which is then frozen and shaped into a plank. The plank is sliced into unit portions which are then pressed into shaped portions with a preferred, or other, press. One preferred press linearly reciprocates unit portions into the press. This or another preferred press imparts three dimension exterior shape to the pressed food products. Full Article
z Tire vulcanizer By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT What is provided is a tire vulcanizer, in which the stress force during engagement of the teeth can be reduced and teeth damage can be suppressed, allowing down-sizing, light-weighting, and simplifying at the same time. It includes: an upper mold attaching part (21) to which an upper mold is attached; a lower mold attachment part to which a lower mold pressed on the upper mold is attached; a supporting part (5) that supports the upper mold attaching part (21) and the lower mold attaching part; a fixed side rack (6) having first teeth (6a) arranged in a height direction and provided to the supporting part (5); a movable-side rack (7) having second teeth (7a) engaging with the first teeth and provided to the upper mold attaching part (21); and a tilting restriction part (40) restricting tilt of the movable-side rack (7) derived from the height direction. Full Article
z Utilizing a diluent to lower combustion instabilities in a gas turbine engine By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A method of influencing combustion dynamics, including measuring a combustion dynamics parameter, and controlling a diluent flow (26) delivered to a fuel flow (32) upstream of a pilot burner fuel outlet (40) in response to the measured combustion dynamics parameter. Full Article
z Polymerizable tertiary ester compound, polymer, resist composition, and patterning process By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention provides a polymerizable tertiary ester compound represented by the following general formula (1a) or (1b). There is provided a polymerizable ester compound useful as a monomer for a base resin of a resist composition having a high resolution and a reduced pattern edge roughness in photolithography using a high-energy beam such as an ArF excimer laser light as a light source, especially in immersion lithography, a polymer containing a polymer of the ester compound, a resist composition containing the polymer as a base resin, and a patterning process using the resist composition. Full Article
z Generalization of shot definitions for mask and wafer writing tools By www.freepatentsonline.com Published On :: Tue, 15 Sep 2015 08:00:00 EDT Techniques for reducing the number of shots required by a radiation beam writing tool to write a pattern, such as fractured layout design, onto a substrate. One or more apertures are employed by a radiation beam writing tool to write a desired pattern onto a substrate using L-shaped images, T-shaped images, or some combination of both. By reducing the number of shots required to write a pattern onto a substrate, various implementations of the invention may reduce the write time and/or write complexity of the write process. Full Article
z Electronic musical instrument with quantized resistance strings By www.freepatentsonline.com Published On :: Tue, 04 Sep 1990 08:00:00 EDT For reading the frets of a stringed electronic musical instrument, a plurality of resistance wire strings are secured to a nut end and a bridge of the instrument, with the strings superposing in parallel relationship over a plurality of conducting frets mounted on a fingerboard on the instrument. The voltages produced by depressing the strings to the conducting frets, after being inverted and linearized, are quantized to levels representative of the particular frets to obviate the effects of contact resistance, and decision voltage levels are selected so as to account for such contact resistance. To enable the signals to be fed as conventional information through a MIDI channel to a synthesizer for generating frequencies corresponding to the signals, an analog to digital converter is used. The different components, as well as the digitized linearized signals, are selectively controlled and fed, respectively, to a microprocessor. Full Article
z Optimization of waveform operation in electronic musical instrument By www.freepatentsonline.com Published On :: Tue, 11 Sep 1990 08:00:00 EDT An electronic musical instrument having a number of keys, having tone generators capable of simultaneous tone production, the tone generators being smaller in number than the number of keys. The instrument forms an operation for synthesizing a desired waveform, the operation for synthesizing a desired waveform being performed in a repeating cyclic order with an operation cycle and in which the waveform is transferred to the tone generators and read out therefrom at a rate in accordance with the note of a key being depressed to obtain a desired musical waveform. The device includes a number-of-depressed keys detecting device which counts the number of keys which are actuating the tone generator upon depression. A cycle altering device is provided for changing the operation cycle, as a whole, on the basis of the number of depressed keys, counted by the number-of-depressed keys detecting device. The construction allows for a waveform of a smooth temporal variation to be produced. Full Article
z Music synthesizer with multiple movable bars By www.freepatentsonline.com Published On :: Tue, 30 Oct 1990 08:00:00 EST A variable control device accessory for a music synthesizer having a horizontally disposed keyboard. The device is positioned in front of the keyboard. It has a plurality of movable bars, at least of one of which is capable of being pivotally and slidably moved by the wrist of a player while all the others are only slidable. The bars modulate selected light beams focussed on light responsive mechanisms to produce variably dependent analog signals as inputs to the music synthesizer. Full Article
z Electronic synthesized steelpan drum By www.freepatentsonline.com Published On :: Tue, 18 Apr 2006 08:00:00 EDT An electronic synthesized steelpan drum resembling a conventional steelpan drum and featuring the same shallow cylindrical shape with a sunken concave playing surface. The steelpan drum includes a central processor chip and associated memory chips for providing a variety of synthesized steelpan and a full range of musical, orchestral, and symphonic instrumental sounds, including tenor, double-seconds, guitar, cello, quadraphonic, tenor-bass, and bass steel drums. The concave playing surface is comprised of a series of rubber striking pad areas, which can be arranged in a conventional or other unique pattern typical of a tenor pan. The striking pad areas will be played with a pair of pansticks. Attached under each pad is a pressure sensor, which will detect the amount of force applied when a pannist strikes a pad and provide a signal to the central processor for controlling the synthesized sound. The steelpan has various control functions including speakers, volume control, function selection buttons, and a control display panel. Full Article
z Method and apparatus for efficient zone switch operation in a broadband wireless access system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A wireless access system and, more particularly, a method and apparatus for more efficiently performing zone switch are disclosed. The method of performing zone switch by an advanced mobile station (AMS) in a mixed-mode advanced base station (ABS) which operates in a mixed mode of a broadband wireless access system includes receiving a ranging response (RNG-RSP) message including system information of an AMS support zone from a legacy zone (LZone) of the ABS, and performing ranging to the AMS support zone using the system information. Full Article
z ACK/NACK channelization for resource blocks containing both ACK/NACK and CQI By www.freepatentsonline.com Published On :: Tue, 23 Jun 2015 08:00:00 EDT In one exemplary embodiment, a method includes: transmitting a value from an access node towards an apparatus, where the value is indicative of a size of a first portion of an uplink resource block, where the uplink resource block is shared among a plurality of apparatus, where the first portion is specified for transmission of a first type of signaling to the access node, where a second portion of the uplink resource block is specified for transmission of a second type of signaling to the access node; and receiving at least one transmission using at least one of the first portion and the second portion. Full Article
z Systems and methods for prioritizing and scheduling packets in a communication network By www.freepatentsonline.com Published On :: Tue, 23 Jun 2015 08:00:00 EDT Systems and methods provide a parameterized scheduling system that incorporates end-user application awareness and can be used with scheduling groups that contain data streams from heterogeneous applications. Individual data queues within a scheduling group can be created based on application class, specific application, individual data streams or some combination thereof. Application information and Application Factors (AF) are used to modify scheduler parameters such as weights and credits to differentiate between data streams assigned to a scheduling group. Dynamic AF settings may adjust relative importance of user applications to maximize user Quality of Experience (QoE) in response to recurring network patterns, one-time events, application characteristics, protocol characteristics, device characteristics, service level agreements, or combinations thereof. Scheduling parameters may be dynamic and incorporate the notions of “duration neglect” and “recency effect” in an end-user's perception of video quality in order to optimally manage video traffic during periods of congestion. Full Article
z Maize hybrid X08D387 By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated X08D387 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08D387 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08D387 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08D387, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08D387. This invention further relates to methods for producing maize varieties derived from maize variety X08D387. Full Article
z Maize inbred PH1W03 By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1W03 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1W03 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1W03 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1W03 or a locus conversion of PH1W03 with another maize variety. Full Article
z Maize inbred PH1MBR By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1MBR and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MBR with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1MBR through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1MBR or a locus conversion of PH1MBR with another maize variety. Full Article
z Maize inbred PH1K8P By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1K8P and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1K8P with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1K8P through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1K8P or a locus conversion of PH1K8P with another maize variety. Full Article
z Maize inbred PH1KHH By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1KHH and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KHH with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KHH through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KHH or a locus conversion of PH1KHH with another maize variety. Full Article
z Maize inbred PH18WR By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH18WR and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH18WR with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH18WR through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH18WR or a locus conversion of PH18WR with another maize variety. Full Article
z Maize inbred PH1M0H By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1M0H and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1M0H with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1M0H through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1M0H or a locus conversion of PH1M0H with another maize variety. Full Article
z Maize inbred PH1KAP By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1KAP and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KAP with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KAP through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KAP or a locus conversion of PH1KAP with another maize variety. Full Article
z Maize inbred PH18PF By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH18PF and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH18PF with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH18PF through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH18PF or a locus conversion of PH18PF with another maize variety. Full Article
z Maize inbred PH1TDJ By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated PH1TDJ and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1TDJ with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1TDJ through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1TDJ or a locus conversion of PH1TDJ with another maize variety. Full Article
z Maize hybrid X131C721 By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A novel maize variety designated X130721 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X130721 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X130721 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X130721, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X130721. This invention further relates to methods for producing maize varieties derived from maize variety X130721. Full Article
z Mixing apparatus for frozen products By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT An apparatus for mixing frozen desserts has a mixing chamber, and a spindle with driving portion for rotating the spindle. The mixing chamber has two main parts having a funnel and a top chamber forming a closed mixing chamber when brought together. The spindle is accommodated through the top chamber. Full Article
z Eddy current minimizing flow plug for use in flow conditioning and flow metering By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT An eddy-current-minimizing flow plug has an outer radial wall with open flow channels formed between the plug's inlet and outlet. The plug has a central region coupled to the inner surface of the outer radial wall. Each open flow channel includes (i) a first portion originating at the inlet and converging to a location in the plug where convergence is contributed to by changes in thickness of the outer radial wall and divergence of the central region, and (ii) a second portion originating in the plug and diverging to the outlet where divergence is contributed to by changes in thickness of the outer radial wall and convergence of the central region. For at least a portion of the open flow channels, a central axis passing through the first and second portions is non-parallel with respect to the given direction of the flow. Full Article
z Dinitroxide-type biradical compounds optimized for dynamic nuclear polarization (DNP) By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The present invention relates to the field of organic chemistry and in particular to organic free radicals used as polarizing agents in the technique of Dynamic Nuclear Polarization (DNP), which involves transferring the polarization of electron spins to the nuclei of a compound whose Nuclear Magnetic Resonance (NMR) is being observed. It concerns Dinitroxide-type Biradical polarizing agents characterized by a rigid linkage between the aminoxyl groups of said nitroxide units. This particular structure enables, at low temperatures and high fields, optimal transfer of polarization and optimal enhancement of NMR/MAS signals of the polarized nuclei of the compound studied. Full Article
z Process for preparing a compound useful for producing an optically active diazabicyclooctane compound By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A process for preparing the compound of the following formula (E): wherein Bn represents a benzyl group, and tBu represents a tert-butyl group, the process including: (a) subjecting the following compound (B) to trifluoroacetylation, wherein tBu represents a tert-butyl group to produce the following compound (C): wherein tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; (b) reacting the compound (C) with benzyloxyamine in the presence of a hydroxyl group activating agent to produce the following compound (D): wherein Bn represents a benzyl group, tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; and (c) subjecting the compound (D) to detrifluoroacetylation. Full Article
z N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides and use thereof as herbicides By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A description is given of N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides of the general formula (I) as herbicides. R in this formula (I) stands for radicals such as hydrogen, organic radicals, and other radicals such as halogen. W stands for a substituted pyridyl radical. Full Article
z [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention is directed to a compound of Formula (I) and to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention. Full Article
z Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The invention is directed to novel substituted benzylamino quinolines, compounds comprising substituted benzylamino quinolines, methods of making substituted benzylamino quinolines, the use of substituted benzylamino quinolines for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism, and the use of substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors. Full Article
z Amino azaheterocyclic carboxamides By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer. Full Article
z 1H-benzimidazole-5-carboxamides as anti-inflammatory agents By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer. Full Article
z Method of preparing benzoimidazole derivatives By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT This invention relates to a method of preparing a benzoimidazole derivative at high purity and high yield so as to enable the production of the benzoimidazole derivative compound as an antagonist against a vanilloid reactor-1, and particularly to a method of preparing a benzoimidazole derivative at high purity and high yield, wherein the benzoimidazole derivative is synthesized using a novel intermediate, namely, benzaldehyde, and thereby the preparation process is simple so that it can be applied to production. Full Article
z Substituted pyridine and pyrazine compounds as PDE4 inhibitors By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The invention provides a chemical entity of Formula (I) wherein R1, R2, R3, R4, Y and Z have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies, detection and imaging techniques, and radioactive treatments; and therapies, including inhibiting PDE4, enhancing neuronal plasticity, treating neurological disorders, providing neuroprotection, treating a cognitive impairment associated with a CNS disorder, enhancing the efficiency of cognitive and motor training, providing neurorecovery and neurorehabilitation, enhancing the efficiency of non-human animal training protocols, and treating peripheral disorders, including inflammatory and renal disorders. Full Article
z Luminescent platinum(II) complexes with biazolate chelates By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A platinum complex of a formula (I): whereR1 and R2 are each fluoroalkyl,X is C—H or nitrogen, andL1 is a bidentate, nitrogen-containing heteroaromatic ligand. Full Article
z Bicyclic thiazoles as allosteric modulators of mGluR5 receptors By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to novel bicyclic thiazoles which are positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (“mGluR5”) and which are useful for the treatment or prevention of disorders associated with glutamate dysfunction and diseases in which the mGluR5 subtype of receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which mGluR5 is involved. Full Article
z Method for producing pyridazinone compounds and intermediate thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to a novel method for producing a pyridazinone compound and an intermediate thereof as shown in the following scheme: wherein the symbols are as defined in the specification. Full Article
z Magnetized nut for fastening a compressor wheel of an exhaust turbocharger to the turbo shaft, and method for the production thereof By www.freepatentsonline.com Published On :: Tue, 16 Apr 2013 08:00:00 EDT A magnetized nut for fastening a compressor wheel of an exhaust turbocharger to a turbo shaft. The nut has a base body made of a non-magnetic material forming a hollow space for accommodating a magnetic material, and a method for the production of the magnetized nut. In order to provide a magnetized nut that is produced in a simple and cost-effective manner and ensures as equal a distribution of mass as possible with regard to the rotational axis of the nut, the magnetic material is introduced into the hollow space using injection molding. Full Article
z Abrasive tool for use as a chemical mechanical planarization pad conditioner By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT An abrasive tool including a CMP pad conditioner having a substrate including a first major surface, a second major surface opposite the first major surface, and a side surface extending between the first major surface and the second major, wherein a first layer of abrasive grains is attached to the first major surface and a second layer of abrasive grains is attached to the second major surface. The conditioner further includes a first sealing member extending in a peripheral direction along a portion of the side surface of the substrate. Full Article