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Former India captain MS Dhoni's presence in the current India squad for the WT20 is the biggest topic of debate at the moment. Many cricketers, current and former have their own views.

Former Indian cricketer Krishnamachari Srikkanth shared his views on MS Dhoni’s chances of making it to the Indian team for the 2020 ICC T20 World Cup on Star Sports 1 show Cricket Connected and said “I am not going to be diplomatic. I am talking about if I was the chairman of the selection committee, what would I do. If the IPL does not happen then his chances are very, very bleak. Because straightaway, in my opinion, KL Rahul will be the wicketkeeper-batsman. Rishabh Pant, I still think he might be a bit of a doubt, but I believe that Rishabh Pant is highly talented. So, I wouldn’t mind taking him along with the squad, but definitely, if the IPL doesn’t happen, then Dhoni will have a difficult time getting back into the team for the T20 World Cup. Let’s be very honest about it. He is absolutely fit, he is a legend, he is brilliant. I am a great fan of Dhoni myself. But the question is for the World Cup team. So you’ll have to put the Indian team first and then the individuals.

Meanwhile, former opening batsman Gautam Gambhir also expressed his thoughts on Yuvraj Singh’s recent comments pertaining to role models in the current team and said, “I agree with Yuvraj that there is a dearth of role models in the Indian team currently, like in the 2000s, we had Dravid, Kumble, Laxman, Sourav and Sachin to guide the team. It is important to have senior players around you who can help you when you’re going through a rough patch. Right now, I don’t think there are enough seniors in the Indian camp, who will set aside their self-interest to help youngsters.

Who are the role models in #TeamIndia’s dressing room?

Watch @GautamGambhir, @VVSLaxman281 and other experts weigh in on the discussion and much more on #CricketConnected!

⏳: Saturday, 7 PM
📺: Star Sports Network & Disney+Hotstar pic.twitter.com/fwsyqil4Wp

— Star Sports (@StarSportsIndia) April 15, 2020

Another ex-Test opener VVS Laxman also shared his views on Rohit Sharma not featuring in Wisden Cricketers of the Year list said on Star Sports 1 show Cricket Connected, “I think anyone who follows the game of cricket will be surprised and shocked not to see Rohit Sharma’s name in those five players list. Because yes, The Ashes is an important series, the World Cup is bigger than Ashes. And someone who has scored five hundreds; remember the first hundred was on a tough wicket in Southampton against South Africa and none of the other batsmen got runs. And he played another important knock against Pakistan. I am really shocked and surprised, and every cricketer will be shocked and surprised by this announcement from Wisden.”

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The BCCI on Tuesday told IPL franchises that the event stands "postponed indefinitely" after the lockdown to combat the COVID-19 pandemic was extended till May 3, leaving no scope for the league to take place during its designated window. While the development hasn't been officially announced as yet but it is learnt that the BCCI has reached out to all the stakeholders, including the eight franchises and the broadcasters, to convey that the event stands "postponed and not cancelled".

"Yes, the BCCI has intimated us that IPL has been postponed for the time being but they are hopeful of finding a window later this year as and when things normalise," a veteran franchise official told PTI on conditions of anonymity. It is understood that BCCI president Sourav Ganguly and secretary Jay Shah were waiting for the government directive and once the lockdown was extended till May 3 on Tuesday, they saw no possibility of holding the IPL during its traditional April-May window. Ganguly had repeatedly made it clear that the game cannot be a priority given the crisis that the country is facing. India currently has over 10,000 positive cases with over 350 recorded deaths, making it virtually impossible for the government to lift any of the restrictions put in place last month.

The IPL was supposed to be held from March 29 to May 24. However, on March 13, the BCCI announced that the league would be postponed till April 15 due to the restrictions placed on the entry of foreigners, which ruled out any international participation. The only window for an IPL in the current year would be between September and November, provided Cricket Australia and the ICC agree to reschedule the T20 World Cup. The six-month travel restrictions in Australia end on September 30 if the situation becomes normal and the World Cup is scheduled in October-November. The other option is having a curtailed IPL in six weeks between September and early October as it's highly unlikely that the Asia Cup will happen. England are also unlikely to travel for their white-ball series in India.

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Indian shuttlers Ashwini Ponnappa and N Sikki Reddy have finally got some time to pause and reflect due to the COVID-19 pandemic and they are making the most of it by creating a database to analyse their past performances while waiting for another shot at Olympic qualification. The coronavirus outbreak has left over 1.2 lakh people dead and infected nearly 2 million globally, and brought all sports activities, including badminton, to a halt after countries imposed lockdowns. Ashwini and Sikki are doubles specialists and endured an underwhelming season last year. The time at hand has given them a chace to analyse the past performances.

"We don't have any one to sit and do analysis for us, so now that we have time, I'm doing some analysis of our performance. I am jotting down points, about areas where I can improve. I started with my matches and then other players on tour," Ashwini, who represented India at the London and Rio Olympic Games, told PTI. "You can always watch and analyse and understand the patterns but it is different when you see things on paper. It is more concrete. So trying to set up a complete database. My brother will help me out. He made an app for me in the past." Ashwini and Sikki fell at the first hurdle 13 times in 20 tournaments last year, and exited from the second round thrice.

Ashwini also picked up a calf injury during the Syed Modi International but the duo was still confident of qualifying by performing well in the remaining Olympic qualifiers. But with Badminton World Federation (BWF) cancelling all tournaments due to the coronavirus pandemic, their fate remains uncertain. "The problem is we don't know the new BWF rules regarding the qualification. There is one year left now, you can't take a two year old performance to select for Olympics, it has to be present performance, so we have to wait," said Sikki. "In badminton, there is a ranking cut off, so how will they accommodate the cancelled qualifiers, how will they count the ranking points, everything is too messed up now," she added. Sikki and Ashwini had reached the finals at Hyderabad Open Super 100 and Maldives International Challenge, last year.

The Indian pair is ranked 28th and will need to be inside top 16 on April 29, 2021 -- the new Olympic cut off date. Ashwini said: "Me and Sikki were confident of doing well in the 4-5 tournaments left but now no one knows what would be the criteria of Olympic qualification and BWF can't really say anything with things changing every moment." They are using the coronavirus-forced break to learn cooking, besides doing some wall practice and exercises for physical fitness. Talking about the effects of the lockdown on mental health, Sikki said: "We have been travelling a lot all these years and now for a month, we are at home, it is fine. But what if it is for 2-3 months, then it will get tough to stay away from the game.

"So it is important to stay motivated for once the lockdown is lifted because you will in a comfortable zone in the break and then all of a sudden you will need to push yourself." Ashwini added: "...now that Olympics have been postponed, nothing is certain and it is tough, you have to be really strong." The economic fallout of the coronavirus outbreak has hit sports hard and Ashwini said badminton too will be affected. "It will hit in terms of sponsors, in terms of tournaments being conducted because countries need sponsors to host events, and after this, I'm not sure what the economic status of many countries would be. "The way things are, it is will be tough to host tournaments, it will not be easy for countries to have tournaments with many big companies shut and struggling to survive," she signed off.

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India badminton coach Pullela Gopichand on Thursday emphasized on the need for physical literacy as people around the world are fighting against the COVID-19 pandemic. Gopichand along with Margaret Whitehead, who is an esteemed philosopher and stalwart of the modern interpretation of physical literacy, also highlighted the importance of support from the top leadership to promote the need for Physical Literacy and see it as a key pillar for the national level development.

"Physical literacy is a very important part of our life. I think physical activity needs to take centre stage. Health, fitness and all of these things are important especially in these days of COVID-19. We see the need for it more and more," Gopichand told reporters via video conferencing during ELMS Sports Foundation webinar. "We need a healthy and happy country during these challenging times. Our vision to improve physical literacy, sporting excellence in India has received a huge fillip with the involvement of stalwarts like Gopichand and Whitehead interacting on the subject," ELMS Sports Foundation's co-promoter Vita Dani said.

"A healthier and happier nation is truly the need of the hour, not just during the challenging times we're living in currently, but also in the future as we look to bounce back," she added, in the webinar that was widely attended by government officials, heads of private institutions, leading faculty from Physical Education and the media.

Mentored by two of India's most popular sports legends -- two-time Olympic medal-winning coach Gopichand and Olympic champion shooter Abhinav Bindra -- ELMS Sports Foundation has been making a huge impact highlighting the subject of physical literacy in the country.

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The Navi Mumbai Crime Branch has taken over the probe into the death of a 21-year-old man there during the Maratha quota stir last week. During the violence that erupted in Kopar Khairane area of Navi Mumbai during the Maratha reservation agitation on July 25, Rohan Todkar was assaulted by a mob. He later succumbed to his injuries in the state-run JJ Hospital at Byculla in Mumbai on July 27.

An official said that a murder case had been registered at Kopar Khairane police station against unidentified persons. "The case has been handed over to the Navi Mumbai Crime Branch. Investigations into the incident are underway. No arrests have been made so far," Tushar Doshi, Deputy Commissioner of Police (Crime) told PTI.

Todkar's cousin sister, Shital Shinde, speaking to PTI yesterday, had said that Todkar had ventured out, along with his friends, on July 25 and then got caught in the violence. The youth's last rites were carried out in his native Khonavali village in Patan tehsil in Satara district after authorities assured his family that the culprits would be arrested and compensation would be provided.

Edited by mid-day online desk with inputs from PTI

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Despite cultural upheavals, highlands residents persisted

Cells use complex containers to launch toxic chemicals at their victims

Baresi: I’m lucky to have played at three World Cups

If you liked Ajay Devgn's 2018 mystery thriller Raid, then you will love this bit of news! It's being reported that Devgn's film will soon get a sequel, as the actor and producer Bhushan Kumar are already said to be working on it. Plus, according to a report, Raid will be turned into a multi-film franchise. Excited yet?

A source close to the development informed Mumbai Mirror, "The franchise seeks to bring into the public eye heroes who work closely with intelligence agencies to track white-collar crimes. To this day, nobody knows the identity of the officer on whom Ajay's Amay was modelled. Raid 2 will also be a tribute to men who don’t wear the uniform."

Bhushan Kumar, who produced the first film, told the publication, "It will be a huge multi-film franchise and Ajay Ji and I, along with Kumar Mangat ji, are looking to take Raid forward. The script of Part 2 is being developed. Since the original was a much-loved film, the sequel is a huge responsibility. After the super success of Tanhaji: The Unsung Warrior, there's a lot of pressure on this collaboration to live up to the expectation. We have always aimed at creating high concept films."

Raid, directed by Raj Kumar Gupta, starred Ajay Devgn an IRS officer, Amay Patnaik. While Devgn and Bhushan Kumar are already collaborating on Bhuj: The Pride Of India, news of them reuniting for the Raid series is much welcome for fans of the film!

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Actress Shilpa Shetty and her husband Raj Kundra showed off some Punjabi dance moves in their new video. The couple are killing time during lockdown with some happy dancing, going by their latest TikTok video that has them dancing to a catchy tune. "If you're happy and you know it.. just Balle Balle," read the caption.

Dancing isn't their only fitness secret. Shilpa recently opened up about the workout schedule she and her family follow.

"I had shared a little exercise-fun with Viaan (Shilpa's son) a few days ago, and I was asked for the entire workout video. Well, I don't have the entire workout captured, but sharing what I found from my archives. I truly believe that the family that eats, prays and works out together... stays together!" Shilpa wrote, sharing a glimpse of her workout session with Raj, and their son Viaan.

"Oftentimes when @rajkundra9 and I workout in the mornings, we get Viaan to join us too. We do understand that if it's not fun for him, he's not going to enjoy the process. So, while we roped in some abs workout for ourselves, we got him to hop, slide, and jump around," she added in the social media post.

 

 

 

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I had shared a little exercise-fun with Viaan a few days ago, and I was asked for the entire workout video. Well, I don’t have the entire workout captured, but sharing what I found from my archives. I truly believe that the family that eats, prays and works out together... stays together! Oftentimes when @rajkundra9 and I workout in the mornings, we get Viaan to join us too. We do understand that if it's not fun for him, he's not going to enjoy the process. So, while we roped in some abs workout for ourselves, we got him to hop, slide, and jump around. Our workout helps us build & strengthen the abdominal muscles, while it also helps improve the mind-body coordination and enhances speed & endurance capacity. Viaan, on the other hand, was just happy to be jumping around and using up some of that pent up energy. A morning well-spent, this was! I hope you all are staying home and staying fit too! . @thevinodchanna . . . . #SwasthRahoMastRaho #GetFit2020 #MondayMotivation #FitIndia #FitIndiaMovement #homefitness #homeworkouts #fitness #COVID19

A post shared by Shilpa Shetty Kundra (@theshilpashetty) onApr 19, 2020 at 10:30pm PDT

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Is there anything Kareena Kapoor Khan can't do? She's a talented actor, a style icon, an amazing mum to little Taimur, and just about everything else that makes her uniquely Bebo. She may have joined the Instagram party late, but by now we know that Bebo is the life of any party she joins, even if she does so fashionably late!

Here are five instances on Instagram when Kareena Kapoor showcased her tremendous wit and humour!

When Bebo as a baby shared a gem about social distancing

First of all, how utterly adorable is this photo of a tiny little Kareena Kapoor? She used this throwback photo to talk about social distancing and show us how important it is in the deadly times of corona. Bebo captioned this image, "Me... when someone tries to shake my hand these days!
#StayHome #StaySafe #SocialDistancing"

When she modelled a pasta necklace made by Tim

Even a necklace made from pasta looks good on Bebo, proving that the Good Newwz actor can wear anything and look like a million bucks. This necklace was made by her dear little boy Taimur, and Kareena wrote alongside this picture, "Pasta la vista. Handmade Jewellery by Taimur Ali Khan #QuaranTimDiaries" #QuaranTimDiaries... now isn't that creative?

When Kareena stared in shock at the zit on her face

Yes, Bebo also falls victim to unwarranted and unwanted zits sometimes. But does she fret? No, the queen never frets! Instead, she makes fun of it by writing, "Meanwhile... I just sat there staring in wonder of what was being created. PS: The zit on my face didn't get the memo of no personal visits and social distancing... #HugeMess"

When she wished Aamir Khan in the funniest way

Kareena Kapoor Khan also found the best way to wish her Laal Singh Chaddha co-star, Aamir Khan, a happy birthday. Sharing a photo of a snoozing and pillow-cuddling Aamir, she wrote, "My fav co-star has to be @_aamirkhan's... pillow!" 

When she wanted to fall in love... or was it fall asleep?

Like us, Kareena, too, is bored sitting at home. And while husband Saif Ali Khan can be seen spending his time reading and lazing around in the grass, Kareena seems to be quite unoccupied in this photo! "Fall i̶n̶ ̶l̶o̶v̶e̶ asleep... #Mess" she captioned this cute picture of her passing time with Saif.

Which of Kareena Kapoor's Instagram photos did you like the most?

On the work front, Kareena was recently seen in Irrfan Khan and Radhika Madan's Angrezi Medium. She will be next Laal Singh Chadha opposite Aamir Khan. The film is a remake of Tom Hanks' Forrest Gump (1994) and is helmed by director Advait Chandan. The movie is slated to hit theatres on Christmas 2020.

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Acupuncture may not boost chances of IVF success

Undergoing acupuncture treatment during in vitro fertilisation (IVF) might not increase a woman's chances of conceiving, finds a study. The study, however, showed that acupuncture is no better than placebo for improving IVF success.

Acupuncture, a traditional Chinese medicine in which thin needles are inserted into the body, has become a widely used treatment prior to and during IVF.

It showed no significant benefit from IVF when compared with a short course of acupuncture using dummy needles placed away from "true" acupuncture points.

"Our findings do not support acupuncture as an efficacious treatment compared to sham," lead investigator Caroline Smith, Professor at the Western Sydney University in Australia.

For the study, published in the journal JAMA, the team included over 800 Australian and New Zealand women to examine the effects of acupuncture administered prior to and following an embryo transfer (ET).

The participants were given either acupuncture or a sham acupuncture control (a non-insertive needle placed away from the true acupuncture points).

The results showed the rate of live birth was 18.3 per cent among participants who received acupuncture versus 17.8 per cent who received the sham acupuncture control, a non-significant difference.

While a short course of acupuncture may statistically be no better than sham at improving live birth and pregnancy outcomes, a psycho-social benefit from acupuncture was reported by women undergoing IVF, the researchers said.

"Some studies suggest reproductive outcomes maybe improved when acupuncture is compared with no treatment," Smith said.

"Feeling relaxed and reporting relief from stress and women feeling good about themselves is to be welcomed for women as they undergo an IVF cycle," explained co-author Michael Chapman, Professor at the University of New South Wales, Sydney.

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Among couples being treated for infertility, depression in the male partner was linked to lower pregnancy chances, according to a study.

The study showed that couples in which the male partner had major depression were 60 per cent less likely to conceive and give birth than those in which the male partner did not have major depression.

On the other hand, depression in the female partner was not found to influence the rate of birth.

In addition, intake of a class of antidepressants known as non-selective serotonin reuptake inhibitors (non-SSRIs) was also linked to a higher risk of early pregnancy loss among females being treated for infertility, the study appearing in the journal Fertility and Sterility, noted.

However, SSRIs, another class of antidepressants, were not linked to pregnancy loss. Neither depression in the female partner nor the use of any other class of antidepressant were linked to lower pregnancy rates.

"Our study provides infertility patients and their physicians with new information to consider when making treatment decisions," said Esther Eisenberg, at National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in Maryland, US.

Citing previous studies, the authors noted that 41 per cent of women seeking fertility treatments have symptoms of depression.

Another study of men seeking in-vitro fertilisation (IVF) treatments reported that nearly 50 per cent experienced depression.

For the study, the team analysed data for 1,650 women and 1,608 men to evaluate the potential influence of depression in couples seeking non-IVF treatments.

Among the women, 5.96 per cent were rated as having active major depression, compared to 2.28 per cent of the men.

Women using non-SSRIs were roughly 3.5 times as likely to have a first-trimester pregnancy loss, compared to those not using antidepressants.

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Turns out, sex and some certain virus can provide aid to fight against cancer.

According to a research conducted by the Ottawa Hospital, a common treatment for erectile dysfunction combined with the flu vaccine may be able to help the immune system mop up cancer cells left behind after surgery.

The study showed that this unconventional strategy can reduce the spread of cancer by more than 90 percent in a mouse model. It is now being evaluated in a world-first clinical trial.

"Surgery is very effective in removing solid tumours," said senior author Rebecca Auer.

"However, we're now realizing that, tragically, surgery can also suppress the immune system in a way that makes it easier for any remaining cancer cells to persist and spread to other organs. Our research suggests that combining erectile dysfunction drugs with the flu vaccine may be able to block this phenomenon and help prevent cancer from coming back after surgery."

The current study investigated sildenafil (Viagra), tadalafil (Cialis) and an inactivated influenza vaccine (Agriflu) in a mouse model that mimics the spread of cancer (metastasis) after surgery.

Auer is now leading the first clinical trial in the world of an erectile dysfunction drug (tadalafil) and the flu vaccine in people with cancer.

It will involve 24 patients at The Ottawa Hospital undergoing abdominal cancer surgery. This trial is designed to evaluate the safety and look for changes in the immune system. If successful, larger trials could look at possible benefits to patients.

"We're really excited about this research because it suggests that two safe and relatively inexpensive therapies may be able to solve a big problem in cancer," said Auer. "If confirmed in clinical trials, this could become the first therapy to address the immune problems caused by cancer surgery."

Using a variety of mouse and human models, Auer's team also made progress in understanding how erectile dysfunction drugs and the flu vaccine affect cancer after surgery.

Normally, immune cells called natural killer (NK) cells play a major role in killing metastatic cancer cells. But surgery causes another kind of immune cell, called a myeloid-derived suppressor cell (MDSC), to block the NK cells.

Auer's team has found that erectile dysfunction drugs block these MDSCs, which allows the NK cells to do their job, fighting cancer. The flu vaccine further stimulated the NK cells.

"Cancer immunotherapy is a huge area of research right now, but we're still learning how best to use it in the time around surgery," said first author Lee-Hwa Tai. "This research is an important step forward that opens up many possibilities."

The study is published in the journal OncoImmunology.

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Representational Image

Researchers have developed a remedy to thwart the metastatic spread of breast cancer, a leading cause of death among women. The findings, published in the journal Nature Communications, showed that by inhibiting a protein called TAK1, the researchers were able to reduce lung metastasis in mice with triple-negative breast cancer (TNBC).

TNBC is a deadliest type of breast cancer that comprises 20 per cent of breast cancer cases and is particularly difficult to treat.

"For this subtype of breast cancer, few treatment options are available to target metastasis, and typically, these treatments are associated with high toxicity," said co-author Min Yu, Assistant Professor from the University of Southern California.

"A better understanding of tumour cells and their interactions with organs and tissues could help us design targeted therapies specific for metastasis," Yu added.

According to the study, TAK1 enables malignant cells from the breast to survive in the lungs and form new metastatic tumours.

Metastasis are the most common cause of cancer-related death.

There is already a potential drug, called OXO -- that can inhibit TAK1 -- and presumably make it much more difficult for breast cancer cells to form lung metastases. However, OXO is not stable in the blood, and therefore would not work in patients, the researcher said.

The researchers developed a nanoparticle -- consisting of a tiny fatty sac -- that works like a smart bomb to carry drugs through the bloodstream and deliver them directly to tumours.

The scientists loaded this nanoparticle with OXO, and used it to treat mice that had been injected with human breast cancer cells. While OXO did not shrink primary tumours in the breast, it greatly reduced metastatic tumours in the lungs with minimal toxic side effects.

"For patients with triple-negative breast cancer, systemic chemotherapies are largely ineffective and highly toxic. So nanoparticles are a promising approach for delivering more targeted treatments, such as OXO, to stop the deadly process of metastasis," Yu noted.

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