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Metal-free polycycloaddition of aldehyde-activated internal diynes and diazides toward post-functionalizable poly(formyl-1,2,3-triazole)s

Polym. Chem., 2020, 11,3075-3083
DOI: 10.1039/D0PY00193G, Paper
Baixue Li, Anjun Qin, Ben Zhong Tang
A metal-free polycycloaddition of aldehyde-activated internal diynes and diazides was successfully established and post-functionalizable poly(formyl-1,2,3-triazole)s were readily produced.
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Metallopolymer-block-oligosaccharide for sub-10 nm microphase separation

Polym. Chem., 2020, 11,2995-3002
DOI: 10.1039/D0PY00271B, Paper
Satoshi Katsuhara, Hiroaki Mamiya, Takuya Yamamoto, Kenji Tajima, Takuya Isono, Toshifumi Satoh
The novel high-χ BCPs comprising poly(vinyl ferrocene) and oligosaccharides formed hexagonal cylinder morphology with d values of ∼8 nm. Lamellar morphology with d values of ∼9 nm was also realized by mixing these polymers and glucose.
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Diphenyl Functional Porphyrins and Their Metal Complexes as Visible-Light Photoinitiators for Free-Radical, Cationic and Thiol-Ene Polymerizations

Polym. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0PY00468E, Paper
Davy-Louis Versace, Yusuf Yagci, Agata Blacha-Grzechnik, Nicolas Bogliotti, V. Brezova, Jean-Pierre Malval, Marc Presset, Hugo Marcille
This investigation demonstrates the excellent photoinitiating properties of novel visible-light absorbing diphenylporphyrins (DPPs) for the free-radical (FRP), cationic (CP) and thiol-ene polymerizations under visible LEDs irradiation (405 and 530 nm)...
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Photochromic Meta-diamides for Optical Modulation of Ligand Activity and Neuron Function

Photochem. Photobiol. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0PP00045K, Paper
cuncun zhou, Liping Ren, Yunfan Ji, Xusheng Shao
Photopharmacology offers facile solutions to spatiotemporal control over ligand activity and receptor function. Meta-diamide insecticide acts on insect GABA receptors (GABARs) as an antagonist that causes firing of a neuron....
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Palladium porphyrin complexes for photodynamic cancer therapy: effect of porphyrin units and metal

Photochem. Photobiol. Sci., 2020, Advance Article
DOI: 10.1039/C9PP00363K, Paper
Jingran Deng, Haolan Li, Mengqian Yang, Fengshou Wu
The ROS generation ability and photocytotoxicity of the synthesized porphyrin compounds were enhanced with the number of porphyrin units in the photosensitizers.
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Systole and Diastole: A Metaphor for Living

In this narrative medicine essay, a physician finds in the motion of diastole, the process of letting go and filling up, an apt metaphor for how to handle the burnout, anxiety, and depression of medical training.




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Nucleoside-based fluorescent carbon dots for discrimination of metal ions

J. Mater. Chem. B, 2020, 8,3640-3646
DOI: 10.1039/C9TB02758K, Paper
Tieli Zhou, Jinyi Zhang, Biwu Liu, Shihong Wu, Peng Wu, Juewen Liu
Using nucleosides and citrate as starting materials, a series of fluorescent carbon dots were synthesized showing different quenching properties by metal ions for their detection by a sensor array.
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Novel perylene probe-encapsulated metal–organic framework nanocomposites for ratiometric fluorescence detection of ATP

J. Mater. Chem. B, 2020, 8,3661-3666
DOI: 10.1039/C9TB02319D, Paper
Xiaomeng Zhou, Juanmin Li, Li-Li Tan, Qiang Li, Li Shang
Schematic illustration of PDI@ZIF-8 nanocomposite synthesis and ratiometric fluorescence assay for ATP sensing. 2-MIm: 2-methylimidazole.
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Thin platelet-like COF nanocomposites for blood brain barrier transport and inhibition of brain metastasis from renal cancer

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00724B, Paper
Guiyang Zhang, Bo Jiang, Chunyong Wu, Yanfeng Liu, Yidan He, Xin Huang, Wei Chen, Kai Xi, Hongqian Guo, Xiaozhi Zhao, Xudong Jia
A drug-loaded polymer–COF nanocomposite has been developed to cross the blood brain barrier and treat brain metastasis from renal cancer.
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Phosphates-responsive 2D-Metal─Organic-Framework-Nanozymes for Colorimetric Detection of Alkaline Phosphatase

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/C9TB02542A, Paper
Xiaoyu Wang, Xiaoqian Jiang, Hui Wei
In this study, a simple colorimetric method with tunable dynamic range for alkaline phosphatase (ALP) activity assay was developed by using peroxidase-mimicking two-dimensional-metal─organic-framework (2D-MOF). Phosphates including pyrophosphate (PPi), ATP, and...
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Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

J. Mater. Chem. B, 2020, 8,3789-3800
DOI: 10.1039/D0TB00046A, Paper
Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.
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Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00357C, Paper
Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Lili Zhu, Jianxiang Shi, Wenxue Tang, Wang Ma, Hong Zong, Wei Jiang
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer tissues and inefficient reactive oxygen species (ROS) production.
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One-pot synthesis of trypsin-based magnetic metal–organic frameworks for highly efficient proteolysis

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02315A, Paper
Chao Zhong, Zhixian Lei, Huan Huang, Mingyue Zhang, Zongwei Cai, Zian Lin
A facile approach was developed for one-pot synthesis of trypsin-based magnetic ZIF-8, which could be applied as an immobilized enzyme microreactor for rapid digestion of proteins.
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Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00620C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Conor C. Horgan, Anika Nagelkerke, Thomas E. Whittaker, Valeria Nele, Lucia Massi, Ulrike Kauscher, Jelle Penders, Mads S. Bergholt, Steve R. Hood, Molly M. Stevens
Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling.
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Drug metabolism in drug design and development : basic concepts and practice / edited by Donglu Zhang, Mingshe Zhu, W. Griffith Humphreys




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Metal ions and their complexes in medication / edited by Astrid Sigel and Helmut Sigel




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Detection of drugs and their metabolites in oral fluid / Robert M. White, Sr. (Retired from RTI International, Research Triangle Park, NC; RMW Consulting, Inc., Naples, FL, USA), Christine M. Moore (Immunalysis Corporation (now a part of Abbott), Pomona,

White, Robert M., author




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Metabolomics: from fundamentals to clinical applications / Alessandra Sussulini, editor

Online Resource




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[ASAP] Exploring the Parameter Space of <italic toggle="yes">p</italic>-Cresyl Sulfate Adsorption in Metal–Organic Frameworks

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c04203




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[ASAP] Highly Efficient Separation of Anionic Organic Pollutants from Water via Construction of Functional Cationic Metal–Organic Frameworks and Mechanistic Study

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c02624




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[ASAP] Rational Design of Ion Transport Paths at the Interface of Metal–Organic Framework Modified Solid Electrolyte

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c04387




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[ASAP] Frequency-Domain and Spatial-Domain Reconfigurable Metasurface

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c02467




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[ASAP] Genetic Engineering-Facilitated Coassembly of Synthetic Bacterial Cells and Magnetic Nanoparticles for Efficient Heavy Metal Removal

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c04512




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[ASAP] A Nanocomposite Vehicle Based on Metal–Organic Framework Nanoparticle Incorporated Biodegradable Microspheres for Enhanced Oral Insulin Delivery

ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.0c04303




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[ASAP] Detergent-Free Simultaneous Sample Preparation Method for Proteomics and Metabolomics

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00662




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[ASAP] Evaluation of Injury Degree of Adriamycin-Induced Nephropathy in Rats Based on Serum Metabolomics Combined with Proline Marker

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00785




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[ASAP] Bioinformatics Analysis of Metabolomics Data Unveils Association of Metabolic Signatures with Methylation in Breast Cancer

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00755




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[ASAP] High Resolution GC-Orbitrap-MS Metabolomics Using Both Electron Ionization and Chemical Ionization for Analysis of Human Plasma

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00774




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[ASAP] Metabolomic Profiling of the Synergistic Effects of Ginsenoside Rg1 in Combination with Neural Stem Cell Transplantation in Ischemic Stroke Rats

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00639




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[ASAP] Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00035




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[ASAP] Metabolomics and Lipidomics Profiling in Asymptomatic Severe Intracranial Arterial Stenosis: Results from a Population-Based Study

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00644




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[ASAP] Metabolomic Profiling of the Aqueous Humor in Patients with Wet Age-Related Macular Degeneration Using UHPLC–MS/MS

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00036




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[ASAP] Dried Blood Spot-Based Metabolomic Profiling in Adults with Cystic Fibrosis

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00031




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Appraising spin-state energetics in transition metal complexes using double-hybrid models: accountability of SOS0-PBESCAN0-2(a) as a promising paradigm

Phys. Chem. Chem. Phys., 2020, 22,9388-9404
DOI: 10.1039/D0CP00807A, Paper
Mojtaba Alipour, Tahereh Izadkhast
Through a comprehensive survey, reliable double-hybrid models have been validated and proposed for spin-state energetics in transition metal complexes.
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Synthesis and Photophysics of Gold(I) Alkynyls Bearing a Benzothiazole-2,7-Fluorenyl Moiety: A Comparative Study Analyzing Influence of Ancillary Ligand, Bridging Moiety, and Number of Metal Centers on Photophysical Properties

Phys. Chem. Chem. Phys., 2020, Accepted Manuscript
DOI: 10.1039/D0CP01539C, Paper
Joseph J Mihaly, Alexis Phillips, David J Stewart, Zachary M Marsh, Christopher McCleese, Joy E. Haley, Matthias Zeller, Tod Grusenmeyer, Thomas Gray
Three new gold(I) alkynyl complexes (Au-ABTF(0-2)) containing a benzothiazole fluorenyl moiety, with either an organic phosphine or N-heterocyclic carbene as ancillary ligand, have been synthesized and photophysically characterized. All three...
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Metal–organic framework-based nanomaterials for photocatalytic hydrogen peroxide production

Phys. Chem. Chem. Phys., 2020, Accepted Manuscript
DOI: 10.1039/D0CP01759K, Perspective
Xiaolang Chen , Yoshifumi Kondo Kondo, Yasutaka Kuwahara, Kohsuke Mori, Catherine Louis, Hiromi Yamashita
As an environmentally friendly and renewable energy, hydrogen peroxide (H2O2) could be produced photocatalytically through selective two-electron reduction of O2 using effective photocatalysts. Metal organic frameworks (MOFs), as hybrid porous...
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Influence of alkaline-earth metal substitution on structure, electrical conductivity and oxygen transport properties of perovskite-type oxides La0.6A0.4FeO3-δ (A = Ca, Sr and Ba)

Phys. Chem. Chem. Phys., 2020, Accepted Manuscript
DOI: 10.1039/D0CP00247J, Paper
Open Access
Jia Song, De Ning, Henny J M Bouwmeester
Structural evolution, electrical conductivity, oxygen nonstoichiometry and oxygen transport properties of perovskite-type oxides La0.6A0.4FeO3-δ (A = Ca, Sr, and Ba) were investigated. La0.6Ca0.4FeO3-δ (LCF64) and La0.6Sr0.4FeO3-δ (LSF64) show a phase...
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Surface diffusion manifestation in electrodeposition of metal anodes

Phys. Chem. Chem. Phys., 2020, Advance Article
DOI: 10.1039/D0CP01352H, Paper
Bairav S. Vishnugopi, Feng Hao, Ankit Verma, Partha P. Mukherjee
Transformation of the electrodeposition morphology, facilitated by the surface self-diffusion across a step
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[ASAP] Earth-Abundant Bimetallic Nanoparticle Catalysts for Aerobic Ammoxidation of Alcohols to Nitriles

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00670




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A high-throughput targeted metabolomics method for the quantification of 104 non-polar metabolites in cholesterol, eicosanoid, and phospholipid metabolism: application in the study of a CCl4-induced liver injury mouse model

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00385A, Paper
Mengqi Jia, Zhangxiao Peng, Kaige Yang, Changqing Su, Yan Wang, Chao Yan
Experimental workflow of 104 non-polar metabolites in cholesterol, eicosanoid, and phospholipid metabolisms analysis using UPLC-QqQ-MS.
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Nanodiagnostics to monitor biofilm oxygen metabolism for antibiotic susceptibility testing

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00479K, Paper
Megan P. Jewell, Samuel C. Saccomano, Alexa A. David, J. Kirk Harris, Edith T. Zemanick, Kevin J. Cash
A method utilizing oxygen-sensitive nanosensor technology to monitor the oxygen consumption dynamics of living biofilms as they are exposed to antibiotics. This method provides information on the MBIC as well as kinetic response.
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An ultrasensitive electrochemiluminescence aptasensor for the detection of diethylstilbestrol based on the enhancing mechanism of the metal–organic framework NH2-MIL-125(Ti) in a 3,4,9,10-perylenetetracarboxylic acid/K2S2O8 system

Analyst, 2020, 145,3306-3312
DOI: 10.1039/D0AN00212G, Paper
Jingxian Li, Xueling Shan, Ding Jiang, Zhidong Chen
A novel electrochemiluminescence (ECL) aptasensor based on PTCA/NH2-MIL-125 for the determination of diethylstilbestrol.
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Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism

Analyst, 2020, 145,3173-3187
DOI: 10.1039/D0AN00339E, Critical Review
Zhengquan Yan, Hua Yuan, Qi Zhao, Lin Xing, Xiaoyu Zheng, Weiguo Wang, Yulei Zhao, Yang Yu, Lei Hu, Wenli Yao
This work highlights the application and interaction mechanism of metal nanoparticles, metal oxides, metal sulfides, graphene-based nanomaterials and G-quadruplex, etc. in nanoenzyme-based colorimetric sensors.
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Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00288G, Paper
Joohee Park, Hyeongseok Yu, See-Hyoung Park, Keun-Hyeung Lee
A ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.
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Scientific workflow managers in metabolomics: an overview

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00272K, Critical Review
Aswin Verhoeven, Martin Giera, Oleg A. Mayboroda
Metabolomics workflows for data processing reproducibility and accelerated clinical deployment.
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[ASAP] A Synthetic Malonyl-CoA Metabolic Oscillator in <italic toggle="yes">Komagataella phaffii</italic>

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00378




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[ASAP] MAPPS: A Web-Based Tool for Metabolic Pathway Prediction and Network Analysis in the Postgenomic Era

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00397




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[ASAP] Metabolism and Bioactivation: It’s Time to Expect the Unexpected<subtitle>Miniperspective</subtitle>

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00026




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[ASAP] Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00005




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Revisiting metaphors in international relations theory / Michael P. Marks

Online Resource