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CDK11 is required for transcription of replication-dependent histone genes




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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




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Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&T-seq




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CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians




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Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC)

In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins.




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Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40




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UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53




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A standardized patient-centered characterization of the phenotypic spectrum of <i>PCDH19</i> girls clustering epilepsy




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Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis




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Author Correction: <i>Cdkn1a</i> deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation




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CD300f in depression




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Here’s what the CDC is doing about the Zika virus

Find out what steps the CDC is taking to prevent a massive Zika virus outbreak in the United States.

      
 
 




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Perspectives on Impact Bonds: Working around legal barriers to impact bonds in Kenya to facilitate non-state investment and results-based financing of non-state ECD providers


Editor’s Note: This blog post is one in a series of posts in which guest bloggers respond to the Brookings paper, “The potential and limitations of impact bonds: Lessons from the first five years of experience worldwide."

Constitutional mandate for ECD in Kenya

In 2014, clause 5 (1) of the County Early Childhood Education Bill 2014 declared free and compulsory early childhood education a right for all children in Kenya. Early childhood education (ECE) in Kenya has historically been located outside of the realm of government and placed under the purview of the community, religious institutions, and the private sector. The disparate and unstructured nature of ECE in the country has led to a proliferation of unregistered informal schools particularly in underprivileged communities. Most of these schools still charge relatively high fees and ancillary costs yet largely offer poor quality of education. Children from these preschools have poor cognitive development and inadequate school readiness upon entry into primary school.

Task to the county government

The Kenyan constitution places the responsibility and mandate of providing free, compulsory, and quality ECE on the county governments. It is an onerous challenge for these sub-national governments in taking on a large-scale critical function that has until now principally existed outside of government.

In Nairobi City County, out of over 250,000 ECE eligible children, only about 12,000 attend public preschools. Except for one or two notable public preschools, most have a poor reputation with parents. Due to limited access and demand for quality, the majority of Nairobi’s preschool eligible children are enrolled in private and informal schools. A recent study of the Mukuru slum of Nairobi shows that over 80 percent of 4- and 5-year-olds in this large slum area are enrolled in preschool, with 94 percent of them attending informal private schools.

In early 2015, the Governor of Nairobi City County, Dr. Evans Kidero, commissioned a taskforce to look into factors affecting access, equity, and quality of education in the county. The taskforce identified significant constraints including human capital and capacity gaps, material and infrastructure deficiencies, management and systemic inefficiencies that have led to a steady deterioration of education in the city to a point where the county consistently underperforms relative to other less resourced counties. 

Potential role of impact bonds

Nairobi City County now faces the challenge of designing and implementing a scalable model that will ensure access to quality early childhood education for all eligible children in the city by 2030. The sub-national government’s resources and implementation capacity are woefully inadequate to attain universal access in the near term, nor by the Sustainable Development Goal (SDG) deadline of 2030. However, there are potential opportunities to leverage emerging mechanisms for development financing to provide requisite resource additionality, private sector rigor, and performance management that will enable Nairobi to significantly advance the objective of ensuring ECE is available to all children in the county.

Social impact bonds (SIBs) are one form of innovative financing mechanism that have been used in developed countries to tap external resources to facilitate early childhood initiatives. This mechanism seeks to harness private finance to enable and support the implementation of social services. Government repays the investor contingent on the attainment of targeted outcomes. Where a donor agency is the outcomes funder instead of government, the mechanism is referred to as a development impact bond (DIB).

The recent Brookings study highlights some of the potential and limitations of impact bonds by researching in-depth the 38 impact bonds that had been contracted globally as of March, 2015. On the upside, the study shows that impact bonds have been successful in achieving a shift of government and service providers to outcomes. In addition, impact bonds have been able to foster collaboration among stakeholders including across levels of government, government agencies, and between the public and private sector. Another strength of impact bonds is their ability to build systems of monitoring and evaluation and establish processes of adaptive learning, both critical to achieving desirable ECD outcomes. On the downside, the report highlights some particular challenges and limitations of the impact bonds to date. These include the cost and complexity of putting the deals together, the need for appropriate legal and political environments and impact bonds’ inability thus far to demonstrate a large dent in the ever present challenge of achieving scale.

Challenges in implementing social impact bonds in Kenya

In the Kenyan context, especially at the sub-national level, there are two key challenges in implementing impact bonds.

To begin with, in the Kenyan context, the use of a SIB would invoke public-private partnership legislation, which prescribes highly stringent measures and extensive pre-qualification processes that are administered by the National Treasury and not at the county level. The complexity arises from the fact that SIBs constitute an inherent contingent liability to government as they expose it to fiscal risk resulting from a potential future public payment obligation to the private party in the project.

Another key challenge in a SIB is the fact that Government must pay for outcomes achieved and for often significant transaction costs, yet the SIB does not explicitly encompass financial additionality. Since government pays for outcomes in the end, the transaction costs and obligation to pay for outcomes could reduce interest from key decision-makers in government.

A modified model to deliver ECE in Nairobi City County

The above challenges notwithstanding, a combined approach of results-based financing and impact investing has high potential to mobilize both requisite resources and efficient capacity to deliver quality ECE in Nairobi City County. To establish an enabling foundation for the future inclusion of impact investing whilst beginning to address the immediate ECE challenge, Nairobi City County has designed and is in the process of rolling out a modified DIB. In this model, a pool of donor funds for education will be leveraged through the new Nairobi City County Education Trust (NCCET).

The model seeks to apply the basic principles of results-based financing, but in a structure adjusted to address aforementioned constraints. Whereas in the classical SIB and DIB mechanisms investors provide upfront capital and government and donors respectively repay the investment with a return for attained outcomes, the modified structure will incorporate only grant funding with no possibility for return of principal. Private service providers will be engaged to operate ECE centers, financed by the donor-funded NCCET. The operators will receive pre-set funding from the NCCET, but the county government will progressively absorb their costs as they achieve targeted outcomes, including salaries for top-performing teachers. As a result, high-performing providers will be able to make a small profit. The system is designed to incentivize teachers and progressively provide greater income for effective school operators, while enabling an ordered handover of funding responsibilities to government, thus providing for program sustainability.

Nairobi City County plans to build 97 new ECE centers, all of which are to be located in the slum areas. NCCET will complement this undertaking by structuring and implementing the new funding model to operationalize the schools. The structure aims to coordinate the actors involved in the program—donors, service providers, evaluators—whilst sensitizing and preparing government to engage the private sector in the provision of social services and the payment of outcomes thereof.

Authors

  • Humphrey Wattanga
     
 
 




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Trump’s CDC directive isn’t just a war on words. It’s a war on science.

When it comes to science policy, we should take President Trump at his word. On Friday, the Trump administration prohibited officials at the Center for Disease Control and Prevention from using seven words and phrases within 2018 budget documents: “vulnerable,” “entitlement,” “diversity,” “transgender,” “fetus,” “evidence-based,” and “science-based”.  Public outrage flared up against the Orwellian-style censorship,…

       




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Early Voting: A Live Web Chat with Michael McDonald


Event Information

September 26, 2012
12:30 PM - 1:00 PM EDT

Online Only
The Brookings Institution
1775 Massachusetts Ave., NW
Washington, DC

Register for the Event

Thousands of Americans are already casting their votes in the 2012 elections through a variety of vote-by-mail and in-person balloting that allows citizens to cast their votes well in advance of November 6. From military personnel posted overseas to absentee voters, these early voting opportunities give voters the opportunity to make their voices heard even when they can’t stand in line on Election Day. However, there are pitfalls in the process.

Expert Michael McDonald says that while a great deal of attention has been focused on voter fraud, the untold story is that during the last presidential election, some 400,000 absentee ballots were discarded as improperly submitted. How can early voters make sure their voices are heard? What effect will absentee and other early voting programs have in this election year? On September 26, McDonald took your questions and comments in a live web chat moderated by Vivyan Tran of POLITICO.

12:30 Vivyan Tran: Welcome everyone, let's get started.

12:30 Michael McDonald: Early voting was 30% of all votes cast in the 2008 election. My expectation is that 35% of all votes in 2012 will be cast prior to Election Day. In some states, the volume will be much higher. In the battleground state of CO, about 85% of the votes will be cast early; 70% in FL; and 45% in Ohio.

What does it all mean? Hopefully I will be able to answer that question in today's chat!

12:30 Comment from JMC: At what point do you think that the in person early voters become less partisan types eager to cast their vote and more "regular folks" who would be more swayed by debate performances, TV ads, and the like?

12:30 Comment from Jason: 400,000 absentee ballots were discarded in 2008? How?

12:30 Michael McDonald: Reasons why election officials reject mail ballots: unsigned, envelope not sealed, multiple ballots in one envelope, etc. 400K rejected in 2008 does not include the higher rate of spoiled ballots that typically occur with paper mail ballots compared to electronic recording devices used in polling places. Moral: make sure you follow closely the proper procedures to cast your mail ballot!

12:31 Michael McDonald: @JMC: If they are going to vote early, most people wait until the week prior to the election. Those voting now have already made up their minds. But, the polls indicate many people have already done so, so maybe we see more early voting in 2012 as a consequence.

12:31 Comment from User: It was my understanding that absentee ballots are never counted unless the race is incredibly close in a particular state? Is that true - or do the rules for that vary by state?

12:32 Michael McDonald: No, all early votes are counted. What may not be counted, depending on state law and if the election is close enough for them to matter, are provisional ballots.

12:33 Comment from Damion: The blurb here says 400,000 early votes were discarded. Shouldn't the board of elections be reprimanded for that? Who was at fault and what consequences were there?

12:33: Michael McDonald: No, these are ballots "discarded" because people did not follow proper procedures and they must be rejected by law.

12:33 Comment from Shirley: Can you Facebook your vote in?

12:34 Michael McDonald: No. However, election officials are transmitting ballots electronically to overseas citizens and military voters. Voters must print the ballot, fill it out, sign it, scan it, and return. There are ways for these voters to verify that their ballot was received.

12:35 Comment from Karen K: What kind of impact could these discards have on the 2012 election?

12:36 Michael McDonald: Difficult to say. More Republicans vote by mail (excluding all mail ballot states). But, we don't know much about those who fail to follow the procedures. They might be less educated or elderly, and thus might counter the overall trend we see in mail balloting. Who knows?

12:37 Comment from User: This is the first I've heard of so many early votes getting discarded. Is this an issue people are addressing in a serious way?

12:38 Michael McDonald: Unfortunately, we are too focused on issues like voter fraud, which are low occurrence events, when there are many more important ways in which votes are lost in the system. Hopefully we can get the message out so fewer people disenfranchise themselves.

12:39 Comment from Anonymous: What do we know so far about absentee votes for 2012? Can we tell who they're leaning toward in specific states and how?

12:40 Michael McDonald: It's a little early :) yet. One of the major changes from 2008 is that the overseas civilian ballots -- a population that leans D -- was sent ballots much earlier this year than in 2008. We'll get a much better sense of the state of play in the two weeks prior to the election.

12:41 Michael McDonald: That said, the number of absentee ballot requests is running about the same as in 2008, if not a little higher, suggesting that the early vote will indeed be higher than in 2008, and perhaps that overall turnout will be on par with 2008, too.

12:41 Comment from Leslie: So, how can I ensure my early ballot is counted? There are so many rules and regulations, I'm never sure I've brought/filled out the paperwork.

12:42 Michael McDonald: Many states and localities allow people to check on-line the status of their ballot. Do a search for your local election official's webpage to see if that is available to you.

12:42 Comment from Daryyl: Can you define provisional ballots then?

12:44 Michael McDonald: Provisional ballots are required under federal law to allow people to vote if there is a problem with their voter registration. Election officials work after the election to resolve the situation.

If you vote in-person early, then you can resolve provisional ballot situations much sooner, which is good.

12:45 Michael McDonald: Some states use provisional ballots for other purposes: e.g., for a person who does not have the required id or to manage a change in voter registration address. One of the untold stories of this cycle is that FL will manage change of reg. address through provisional ballots. OH does so, and 200K provisionals were cast in 2008. Expect 300K in FL, which may mean we will not know the outcome in FL until weeks after the election. Can you say 2000?

12:45 Comment from Mark, Greenbelt: Is early voting a new phenomenon, or is it increasing? It seems we should make it easier for people to vote when they can.

12:46 Michael McDonald: We are seeing more people vote early, particularly in states that offer the option. However, only MD changed its law from 2008 to allow in-person early voting. OH is sending absentee ballot requests to all registered voters, which is not a change in law, but a change in procedure that is expected to significantly increase early voting there.

12:47 Comment from Jennifer S. : Why do we vote on Tuesday? It seems inconvenient. Wouldn't more people vote if we did it on the weekend? Or over a period of days that offered both morning and evening hours?

12:48 Michael McDonald: We used to have early voting in the US! Back at the Founding, elections were held over several days to allow people living in remote areas to get to the courthouse (the polling place back in the day) to vote. In the mid-1840s, the federal gov't set the current single day for voting because -- what else? -- claims of vote fraud. That people could vote more than once.

12:49 Comment from Winston: What percentage of the U.S. population votes? And, if you could make one change that would increase voting in the U.S. what would be?

12:50 Michael McDonald: I also calculate turnout rates for the country for the media and academics. 62.2% of the eligible voters cast a ballot that counted in 2008. If I were to wave a magic wand, I would have election day registration. California just adopted it yesterday (but starting 2015). States with EDR have +5-7 percentage points of turnout.

12:50 Comment from Bernie S.: One of your colleagues at Brookings, Bill Galston, has suggested that we make voting mandatory, as they do in Australia. What do you think of that idea? Is it even possible here?

12:51 Michael McDonald: That will never happen in a county that values individual freedom so deeply as the US. Fun fact: a few years back, AZ voters rejected a ballot initiative to have voters entered into a lottery.

12:51 Comment from James: If early voting becomes more and more common, shouldn't candidates start campaigning earlier?

12:53 Michael McDonald: They do. In fact, you will see the presidential candidates visit battleground states that have in-person early voting at the start of the period. In 2008, you could see how early voting increased in places where Obama held rallies.

12:53 Comment from Devi P. : What are the factors that drive turnout? How do we get people to the polls? And what can you say about the "microtargeting" strategies the political parties are using to get their voters out?

12:54 Michael McDonald: One of the major ways in which elections have changed in the past decade is that campaigns now place more effort into voter contacts. Over 50% of people reported a contact in 2008. These contacts are known to increase turnout rates by upwards of 10 percentage points. Even contacts from Facebook friends seems to matter!

12:54 Comment from Wendy P, Ohio: What's your position on electronic voting? Can't every voting machine be hacked? Isn't plain old paper balloting more secure?

12:56 Michael McDonald: I went to Caltech, so I am sensitive to the potential for hacking. That said, I encourage experimentation so that we can build a better system. There are counties that do hold electronic elections!

12:56 Comment from Leslie: 400,000 seems like a lot - does this actually have impact on the electoral votes, and if so, should we be worried in this coming election that a lengthy recall may occur?

12:57 Michael McDonald: It could affect the outcome. So please spread the word through your networks. This is the #1 way in which votes are lost in the system!

12:57 Comment from JVotes: Perhaps we should microtarget with ballot issues. Many Americans seem disappointed with the two candidates we have to choose from.

12:58 Michael McDonald: Actually, ballot issues are known to increase turnout. But only a small amount in a presidential election, about 1 percentage point. People vote in the main show: the presidential election.

12:58 Michael McDonald: Interesting aside on that: early voting seems to have a small turnout effect in presidential election, but a larger effect in state and local elections.

12:58 Comment from Jaime Ravenet: Is there a reading of the new voter ID requirements (in at least the 9 most contested states) that does not constitute an "abridgment" of citizens' voting rights?

1:00 Michael McDonald: Perhaps under state constitutions. But the US Supreme Court has already ruled in favor of Indiana's id law. Still, that does not mean that lawyers will try to find some way under federal law to overturn them. TX was blocked because their law was determined to be discriminatory, per Sec. 5 of the Voting Rights Act.

1:00 Vivyan Tran: Thanks for the questions everyone, see you next week!

      
 
 




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McDonald's To Offer Fast-Food "McWeddings" in Hong Kong

If soaring wedding costs have you wondering how you can afford it all (and yet, you couldn't be bothered with the effort to put on a more eco-conscious wedding) then McDonald's may have the answer for you.




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Kids ask McDonalds to ditch plastic Happy Meal toys

Their hugely successful petition has even gotten a response – and a promise – from the fast food giant.




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CDC lists oil of lemon eucalyptus as comparable to DEET for mosquitoes

Even the CDC recommends this botanical ingredient as comparable to DEET for repelling disease-carrying insects.




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Build a Micro-Hydropower Generator from CDs and Repurposed Printer Parts

Think you need to be an engineer and spend a bundle to create a mini-hydropower generator? Think again.




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Why I remain skeptical about McDonald's food changes

Everyone is jumping up and down for joy at the fact that McDonald's is now serving antibiotic-free chicken. Please, let's not ignore everything else that's so wrong with the company.




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Old CDs could be re-used in sewage treatment

The disks are coated with zinc oxide nanorods that break apart organic molecules in sewage.




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New CDC report links factory farms to antibiotic resistance (Infographic)

The wide use of antibiotics in factory farms to prevent infections and promote growth is a breeding ground for superbugs.




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William McDonough at Dwell on Design: A More "Effective" Not Just More "Efficient" Future

A compact chicken coop for city dwellers that wheels around the yard and fertilizes soil is on display at "Dwell on Design" this weekend. The show's awards recognize




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William McDonough on Cradle to Cradle, a Terrestrial Space Station, and What Went Wrong in China (Podcast)

Architect and author of Cradle to Cradle talks about green products, his new buildings, and what happened in China.




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McDonalds to begin buying "sustainable beef" in 2016

A new initiative from the fast food giant aims to rethink the global meat industry. But is that even possible?




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McDonald's promises transparency about its food, if only customers will come back

The company has launched a few efforts to reclaim marketshare, from promoting regional specialties to answering questions about food production. Too bad the promotional videos aren't convincing and fail to address the whole issue.





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You can't deal with international trade if not multilaterally, OECD chief says

Angel Gurria, secretary general of the OECD, discusses U.S.-China trade, multilateralism and digital taxes.




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Stocks making the biggest moves in the premarket: Twitter, Comcast, McDonald's, Tapestry & more

The stocks making the biggest moves in premarket trading include Twitter, Comcast, McDonald's Tapestry, and more.




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McDonald's of the future: Are you lovin' it?

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Kashima Antlers 3-2 CD Guadalajara (UAE 2018)

Losing finalists at the 2016 edition of the FIFA Club World Cup, Kashima Antlers defeated Mexico's CD Guadalajara to set up a semi-final against the team that beat them in that 2016 final, Real Madrid.




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Esperance 1-1 (6-5 pens) CD Guadalajara (UAE 2018)

Nine-man Esperance ended their FIFA Club World Cup UAE 2018 campaign on a high after a tense 6-5 penalty shoot-out win against Chivas in the match for fifth place.




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: CD Guadalajara leaves the pitch after the first half during the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: Fans of Kashima Antlers support their team ahead of the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: Fans of Kashima Antlers support their team ahead of the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: Fans of Kashima Antlers support their team ahead of the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: Fans of Kashima Antlers support their team ahead of the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Kashima Antlers v CD Guaalajara - FIFA Club World Cup UAE 2018

AL AIN, UNITED ARAB EMIRATES - DECEMBER 15: (EDITORS NOTE: This image has been converted to black and white) Fans of Kashima Antlers support their team ahead of the FIFA Club World Cup UAE 2018 second round match between Kashima Antlers and CD Guadalajara at Hazza Bin Zayed Stadium on December 15, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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CD Guadalajara fans wave a big flag in the stands

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: CD Guadalajara fans wave a flag in the stands prior to the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Walter Sandoval of CD Guadalajara celebrates with Angel Zaldivar after scoring his team's first goal

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Walter Sandoval of CD Guadalajara celebrates after scoring his team's first goal with Angel Zaldivar of CD Guadalajara during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Michael Perez of CD Guadalajara is challenged by Mohammed Belaili of ES Tunis

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Michael Perez of CD Guadalajara is challenged by Mohammed Belaili of ES Tunis during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by Michael Regan - FIFA/FIFA via Getty Images)




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CD Guadalajara players line up for a team photo

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: CD Guadalajara players line up for a team photo prior to the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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General view inside the stadium during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: General view inside the stadium during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Mohammed Belaili of ES Tunis is challenged by Michael Perez of CD Guadalajara

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Mohammed Belaili of ES Tunis is challenged by Michael Perez of CD Guadalajara during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Anice Badri of ES Tunis is challenged by Michael Perez of CD Guadalajara 

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Anice Badri of ES Tunis is challenged by Michael Perez of CD Guadalajara during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by Michael Regan - FIFA/FIFA via Getty Images)




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Jair Pereira of CD Guadalajara challenges for the ball with Fousseny Coulibaly of ES Tunis

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Jair Pereira of CD Guadalajara challenges for the ball with Fousseny Coulibaly of ES Tunis during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by Michael Regan - FIFA/FIFA via Getty Images)




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Miguel Ponce of CD Guadalajara is challenged by Anice Badri of ES Tunis 

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Miguel Ponce of CD Guadalajara is challenged by Anice Badri of ES Tunis during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by Francois Nel/Getty Images)




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Jose Cardozo, manager of CD Guadalajara gives his team instructions

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Jose Cardozo, Manager of CD Guadalajara gives his team instructions during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)




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Bilel Mejri of ES Tunis battles for possession with Hedgardo Marin of CD Guadalajara

AL AIN, UNITED ARAB EMIRATES - DECEMBER 18: Bilel Mejri of ES Tunis battles for possession with Hedgardo Marin of CD Guadalajara during the FIFA Club World Cup UAE 2018 5th Place Match between ES Tunis and CD Guadalajara at Hazza Bin Zayed Stadium on December 18, 2018 in Al Ain, United Arab Emirates. (Photo by David Ramos - FIFA/FIFA via Getty Images)