As the 2019 FIFA Women's World Cup qualifying group stage kicks off, we explain how Europe's eight berths alongside hosts France will be decided with tight ties in prospect.

The FIFA Women's World Cup qualifying group stage has begun with the likes of England, Norway, Germany, Iceland and Austria all in goalscoring form.

European champions the Netherlands opened qualifying with a dramatic defeat of Norway as Iceland shocked Germany before being held themselves in October's fixtures.

England, Switzerland, Sweden, Italy, Spain and Finland maintained their perfect records but European champions the Netherlands were held by the Republic of Ireland.

Scotland, Norway, Germany and Sweden have joined hosts France, England, Italy and Spain in the finals by winning their qualifying groups.

The Netherlands took Europe's last finals berth after seeing off Denmark and Switzerland in the play-offs.

The United States beat the Netherlands to retain the trophy in Lyon while Sweden pipped England to bronze.

A student-centered approach to teaching mathematics enables students to develop conceptual understanding and to grow as confident mathematicians.

Rick talks with Larry Rosenstock, education icon, the founder and CEO of High Tech High, and recent recipient of the WISE Prize for Education, about what he's learned after a half century in education.

The new Arcade1Up NBA Jam cabinet is the first to feature Wi-Fi internet connectivity, enabling multiplayer with other cabinet owners.

Academic gender gaps in reading and math follow different paths as American students move from their school years into adulthood, according to new federal data.

On the first week of its new term, the U.S. Supreme Court held two hours of intense arguments about whether the main federal job-discrimination law protects gay, lesbian, and transgender employees.

Source: www.businessinsider.com - Saturday, May 09, 2020
Many superyacht crew members have been stuck on their vessels after lockdowns and travel bans were instated due to the coronavirus pandemic. We spoke to crew members who felt 'lucky' to be quarantined in such luxury digs — and grateful to still have jobs and secure wages. There is still plenty of work to be done, but workers also described trivia games, sundeck BBQs, and hot tub nights they're using to pass the time and bond with colleagues. Strict new hygiene and sanitation rules have also been put into place. Visit Business Insider's homepage for more stories . In late March, billionaire businessman David Geffen posted a shot on Instagram taken from his 452-foot superyacht Rising Sun. It was hastily deleted — but not before it had raised more than a few eyebrows and stirred discourse around the 1% and their self-isolation privilege. But it's not just the rare billionaire who is bunkering down on their yacht during the COVID-19 pandemic. Here is another group of people for whom this is a new reality: the yacht's crews.  Before this crisis, there were around 80,000 people employed on pleasure craft around the globe, according to Laurence Lewis, CEO of YPI Crew, a yacht recruitment agency. As countries rushed to close their borders, ports were closed — and overnight, many found themselves unable to travel to get to or leave their yachts.  For many, a superyacht sounds like the dream scenario to see out lockdown. But is it?  "Ther

Professor of Chemistry Paul Cremer is developing a biosensor platform that could be used to perform real-time, continuous detection of SARS-CoV-2, the virus that causes COVID-19.

If you're avoiding commercial synch-and-backup services, but also think NAS is too complicated, Western Digital has just the product for you.

The brightest tech stars, past and present, have chronicled their journeys in book form. Here are some of the best.

We travel to Latvia to find out about one of the fastest-growing youth tournaments in Europe.

Former Newcastle defender Philippe Albert reveals the tactics of the English club's memorable victory against Barcelona in 1997.

In the wake of anti-immigrant violence, we must help make sure that all students feel welcomed, writes Susana Cordova.

The justices hear arguments Nov. 12 on the Trump administration's effort to end deportation relief under Deferred Action for Childhood Arrivals, in a case pitting the administration and GOP-leaning states against a host of education and advocacy groups.

OM Angola helps a war-ravaged society heal itself.

The recent business shutdowns and stay-at-home orders resulting from the coronavirus pandemic haven’t stopped a Penn State student artist from helping her peers show their work remotely after galleries closed across the United States.

A $450,000 grant from the U.S. Agency for International Development’s Feed the Future Innovation Lab for Peanut Research will aid researchers in Penn State’s College of Agricultural Sciences as they explore the potential to empower women farmers in northern Ghana through peanut production.

A new online newsletter offered by Penn State Extension will give readers “the scoop” on the spotted lanternfly.

For more than a year and a half, UN peacekeepers have continuously supported military operations conducted by the Congolese armed forces (FARDC) against the Rwandan rebels of the Democratic Forces for the Liberation of Rwanda (FDLR) in North and South Kivu.

The approaching elections could be important steps toward reviving democracy in Chad, but only if President Idriss Déby opens political space for the opposition beforehand.

Despite the establishment of anti-corruption agencies, Burundi is facing a deepening corruption crisis that jeopardises prospects for lasting peace and stability.

La rechute est le risque majeur des pays post-conflit et l'une des principales raisons de cette rechute s'appelle la corruption.

The deteriorating situation in Burundi is a perfect storm of much that undermines stability in Africa today — presidents seeking impunity and power through dubious new terms, authoritarian regimes muzzling opposition and independent media, regional rivalries stalemating efforts to bring peace and outside powers unwilling or unable to act.

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in the virology, epidemiology and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing towards the development of treatment for COVID-19. Recent studies have revealed many attractive threptic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.

Treatment of exacerbations of chronic Pseudomonas aeruginosa infections in patients with cystic fibrosis (CF) is highly challenging due to hypermutability, biofilm formation and an increased risk of resistance emergence. We evaluated the impact of ciprofloxacin and meropenem as monotherapy and in combination in the dynamic in vitro CDC biofilm reactor (CBR). Two hypermutable P. aeruginosa strains, PAOmutS (MIC_{ciprofloxacin} 0.25 mg/L, MIC_meropenem 2 mg/L) and CW44 (MIC_{ciprofloxacin} 0.5 mg/L, MIC_meropenem 4 mg/L), were investigated for 120h. Concentration-time profiles achievable in epithelial lining fluid (ELF) following FDA-approved doses were simulated in the CBR. Treatments were ciprofloxacin 0.4g every 8h as 1h-infusions (80% ELF penetration), meropenem 6 g/day as continuous infusion (CI; 30% and 60% ELF penetration) and their combinations. Counts of total and less-susceptible planktonic and biofilm bacteria and MICs were determined. Antibiotic concentrations were quantified by UHPLC-PDA. For both strains, all monotherapies failed with substantial regrowth and resistance of planktonic (≥8log₁₀ CFU/mL) and biofilm (>8log₁₀ CFU/cm²) bacteria at 120h (MIC_{ciprofloxacin} up to 8 mg/L, MIC_meropenem up to 64 mg/L). Both combination treatments demonstrated synergistic bacterial killing of planktonic and biofilm bacteria of both strains from ~48h onwards and suppressed regrowth to ≤4log₁₀ CFU/mL and ≤6log₁₀ CFU/cm² at 120h. Overall, both combination treatments suppressed amplification of resistance of planktonic bacteria for both strains, and biofilm bacteria for CW44. The combination with meropenem at 60% ELF penetration also suppressed amplification of resistance of biofilm bacteria for PAOmutS. Thus, combination treatment demonstrated synergistic bacterial killing and resistance suppression against difficult-to-treat hypermutable P. aeruginosa strains.

The off-label use of third generation cephalosporin (3GC) during in ovo vaccination or vaccination of newly hatched chicks, was a common practice worldwide. CMY-2-producing Escherichia coli have been disseminated among broiler production. The objectives of this study were to determine the epidemiological linkage of bla_CMY-2-positive plasmids among broilers both within and outside Japan because grandparent stock and parent stock were imported in Japan. We examined the whole genome sequences of 132 3GC-resistant E. coli isolates collected from healthy broilers during 2002-2014. The predominant 3GC-resistance gene was bla_CMY-2, which was detected in the plasmids of 87 (65.9%) isolates. The main plasmid replicon types were IncI1-I (n=21; 24.1%), IncI (n=12; 13.8%), IncB/O/K/Z (n=28; 32.2%), and IncC (n=22; 25.3%). Those plasmids were subjected to gene clustering and network analyses and plasmid multi-locus sequence typing (pMLST). The chromosomal DNA of isolates was subjected to MLST and single nucleotide variant (SNV)-based phylogenetic analysis.

MLST and SNV-based phylogenetic analysis revealed high diversity of E. coli isolates. ST429 harboring bla_CMY-2-positive IncB/O/K/Z was closely related to isolates from broiler in Germany harboring bla_CMY-2-positive IncB/O/K/Z. pST55-IncI and pST12-IncI1-I and pST3-IncC were prevalent in western Japan. pST12-IncI1-I and pST3-IncC were closely related to those detected in E. coli isolates from chicken in American continent, whereas 26 IncB/O/K/Z were related to those in Europe. These data will be useful to reveal the whole picture of transmission of CMY-2-producing bacteria in and out of Japan.

Six sources confirmed Apple changed its mind on end-to-end encrypted backups two years ago following an FBI complaint and concerns users could lose access to their own data.

The records involved conversation logs between Microsoft support agents and customers across the globe, dating back to 2005. Most of the records were redacted of customer contact information, but not all.

In number 10 in our countdown, I tried to offer a few thoughts to funders as they embraced new agendas and looked to avoid repeating yesterday's missteps.

BACKGROUND:

Mexican-origin women breastfeed at similar rates as white women in the United States, yet they usually breastfeed for less time. In our study, we seek to identify differences in Mexican-origin women’s breastfeeding intentions, initiation, continuation, and supplementation across nativity and country-of-education groups.

Rachel Hooker, who will graduate May 9 with a 3.99 GPA in supply chain and information systems, has been selected as the Smeal College of Business’ spring 2020 supply chain and information systems student marshal.

Both in and out of the virtual classroom, Penn State Lehigh Valley departments are connecting with students during remote learning

Kristina R. Olson
Mar 1, 2016; 137:e20153223-e20153223
ARTICLES

A new endowed scholarship has been created to support those studying science, technology, engineering or math at Penn State Hazleton.

Drs. William and Jean Lovrinic have made an estate commitment to Penn State that will establish a $100,000 scholarship fund at Penn State Hazleton.

It's only a matter of time before your Windows 10 PC begins to run slowly. You can kick the operating system back into high gear with these useful tips. And they won't cost you a penny.