The present technology provides methods for increasing sensitivity of detection and/or quantification of a negatively charged analyte, e.g., an oligonucleotide, using an analytical system that comprises liquid chromatography and mass spectrometry. The methods comprise passing an acidic solution through the analytical system, i.e., through a fluidic path from the mobile phase reservoir to the detector to remove or displace, at least in part, metal ions adsorbed to charged sites in the fluidic path.

Systems and devices incorporating radiation detection, and techniques and materials for improved radiation detection are provided that involve a nano-scintillator exhibiting a linear luminescent emission response to stimulating electromagnetic radiation. The nano-scintillator can include at least one nanocrystal comprising a rare earth element, a lanthanide dopant, and a spectator dopant, wherein the nanocrystal exhibits a linear luminescent emission response to stimulating electromagnetic radiation of wavelengths less than 100 nm. As one example, the nanocrystal is [Y2-xO3; Eux, Liy], where x is 0.05 to 0.1 and y is 0.1 to 0.16, and has an average nanoparticle size of 40 to 70 nm. These nanocrystals can be fabricated through a glycine combustion method.

Superconducting nanowire avalanche photodetectors (SNAPs) have using meandering nanowires to detect incident photons. When a superconducting nanowire absorbs a photon, it switches from a superconducting state to a resistive state, producing a change in voltage that can be measured across the nanowire. A SNAP may include multiple nanowires in order to increase the fill factor of the SNAP's active area and the SNAP's detection efficiency. But using multiple meandering nanowires to achieve high fill-factor in SNAPs can lead to current crowding at bends in the nanowires. This current crowding degrades SNAP performance by decreasing the switching current, which the current at which the nanowire transitions from a superconducting state to a resistive state. Fortunately, staggering the bends in the nanowires reduces current crowding, increasing the nanowire switching current, which in turn increases the SNAP dynamic range.

A fuel additive imparting high lubricity to gasoline and diesel fuels while concurrently increasing miles and reducing emissions. The fuel additive is formed of a plurality of individual components having individual and a combined synergistic effect along with components increasing fuel lubricity which are mixed with a liquid fuel-soluble carrier and added to the fuel supply of internal combustion engines.

The present invention relates to the use of 1,1-diethoxyethane for increasing the knocking resistance of low-boiling gasoline with an initial boiling point (IBP) of 80° C. to 120° C. by at least 40 units (Research Octane Number).

The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.

There is provided a method of desanding a production flow with at least liquid and solid phases. An inlet is connected to a flow line of a sand trap body having a first filter housing defining a first bore and a plurality of second filter housings defining second bores each connected to the first filter housing at spaced intervals transverse to and in fluid communication with the first bore. The flow path between the stand trap inlet and outlet is defined by the first and second housings. A primary filter is inserted into each of the second bores, the production flow is flowed through the sand trap body such that the production flow is filtered by the primary filters, and then a secondary filter is inserted into the first bore. The mesh size of the primary filters is finer than or equal to the mesh size of the secondary filter.

Warriors fans from around the Bay Area flocked to Oakland for a parade through downtown and a rally on the shore of Lake Merritt. The massive crowd spilled into the streets, stopping traffic in many parts of the city, as team members, coaches, staff, and members of government gave speeches to commemorate the Warriors' historic championship.…

Raucous satire Greed throws billionaire Steve Coogan to the lions. British actor Steve Coogan has made a successful comic character-acting career using two basic ingredients: his own voice and someone else’s writing. Time and again, in such outings as In the Loop, Coffee and Cigarettes, the Alan Partridge TV shows, and Stan and Ollie (with Coogan in deep character as Stan Laurel), Coogan arrives in a hail of dialogue, showering the audience with witticisms from his favored point of view – a man so exasperated with his situation that the best response he can think of is to stew in his own juices, noisily.…

From the new releases everyone's talking about to the cult classics they should be, here are five things to stream and skip this week. Well, we still can't go to the movies — it may be the least of our problems, but it still really sucks. So this week we turn our attention to the world of streaming, where approximately 98.87 percent of our entertainment now exists.…

Its inventive menu includes Italian sausage tacos, chicken soup tacos, and botanical teas. Most of us go to cafes for the coffee, the Wi-Fi, or the opportunity to plant ourselves near an outlet, put on our noise-cancelling headphones, and crank out some work on our laptops. Few visit cafes for the food, much less the social interaction.…

Oakland-based Cream Co. Meats announced recently that, for the first time ever, it will start delivering its products on a retail basis. Statewide Covid-19-related shelter-in-place regulations mandated the closure of many restaurants and other businesses that regularly serve and sell Cream Co. products.…

Oakland’s Alphabet Rockers lands a second nomination for best children’s music album for record honoring gender and cultural diversity. The motto of the Alphabet Rockers is: "We make music that makes change." On its most recent album, The Love, the Oakland hip-hop collective lives up to that promise.…

The invention generally relates to assemblies for displacing droplets from a vessel that facilitate the collection and transfer of the droplets while minimizing sample loss. In certain aspects, the assembly includes at least one droplet formation module, in which the module is configured to form droplets surrounded by an immiscible fluid. The assembly also includes at least one chamber including an outlet, in which the chamber is configured to receive droplets and an immiscible fluid, and in which the outlet is configured to receive substantially only droplets. The assembly further includes a channel, configured such that the droplet formation module and the chamber are in fluid communication with each other via the channel. In other aspects, the assembly includes a plurality of hollow members, in which the hollow members are channels and in which the members are configured to interact with a vessel. The plurality of hollow members includes a first member configured to expel a fluid immiscible with droplets in the vessel and a second member configured to substantially only droplets from the vessel. The assembly also includes a main channel, in which the second member is in fluid communication with the main channel. The assembly also includes at least one analysis module connected to the main channel.

A microbial gaseous-fluid sampler for collecting microbial particles from gaseous fluid includes a gaseous-fluid intake portion having a sample head with a plurality of holes. The gaseous-fluid intake portion further includes a collar configured to receive a Petri dish including agar. The plurality of holes define an exit plane that is positioned a distance from the agar within a range of 5.5 millimeters to 7.5 millimeters. The velocity of the air exiting the plurality to holes is within a range of 18.5 meters per second to 20.5 meters per second.

In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.

The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles.

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.

A population of bright and stable nanocrystals is provided. The nanocrystals include a semiconductor core and a thick semiconductor shell and can exhibit high extinction coefficients, high quantum yields, and limited or no detectable blinking.

This month alone, Oakland-based, family-owned Mr. Espresso has already donated over 2,500 pounds of coffee to COVID-19 relief efforts all over the Bay Area.

During the first two weeks of April, the 42-year-old company — founded in Alameda by enterprising Italian-born Carlo Di Ruocco and now renowned as the first and currently only outfit in the nation that uses oak wood to roast its beans — has given coffee to the Alameda County Community Food Bank and San Francisco-Marin Food Bank, Frontline Foods, East Bay FeedER, Clinica de La Raza, St. Anthony’s Dining Room, Loaves and Fishes Family Kitchen, and other food-, health-, homeless-, youth-, and family-assistance programs.…

A method and system for cooling a device (preferably a micro-device), comprising cooling the device by using a lower critical solution temperature (LCST) mixture. Enhancement of heat transfer rates is achieved during phase separation of a two-component system (two-component mixture) with a LCST. Convective heat transfer rates in small diameter pipes and over a vertical (hot) plate are demonstrated.

Embodiments are generally directed to cooling of electronics using folded foil microchannels. An embodiment of an apparatus includes a semiconductor die; a substrate, the semiconductor die being coupled with the substrate; and a cooling apparatus for the semiconductor die, wherein the cooling apparatus includes a folded foil preform, the folded foil forming a plurality of microchannels, and a fluid coolant system to direct a fluid coolant through the microchannels of the folded foil.

HE MAY NOT be held in the highest regard by the public but there’s something to love about Piers Morgan on Good Morning Britain.

The Children at Aurora Theatre Company makes us think deeply. Noble on its face for messages involving climate change and generational responsibility, excellent craft rises foremost as the walk-away reward of Aurora Theatre's new production. Written by Lucy Kirkwood and directed with signature, uncanny brilliance by Barbara Damashek, The Children employs a familiar theatrical construct to reveal the play's layered, complex story in 95 uninterrupted minutes.…

The provocative A Human Ounce at Central Works asks whether the creator can be separate from the creation. Central Works opens its 30th anniversary season with A Human Ounce, a new play by Nicole Parizeau that poses provocative questions. What is the value of great art, literature, music, commerce, scientific discovery — even Peet's coffee — when scandalous information about its creators or owners comes to light?…

Coming on the heels of the AB5 trauma, the coronavirus lockdown poses an extra economic threat. The COVID-19 pandemic has affected all facets of life in California and the world.…

A method for controlling a pressure control mechanism in a turbofan engine having a precooler permitting heat exchange between ambient air and bleed air includes detecting at least one of an engine failure or a bleed system failure, detecting at least one of an ice condition or an activation of an anti-ice system, and actuating the pressure control mechanism, thereby altering the heat exchange between the ambient air and the bleed air.

An assistance device for an aircraft free-turbine turbine engine, the device including first electrical power supply for powering a winding of a starter rotary machine, referred to as a “first” winding, in order to provide first assistance in accelerating the gas generator of the engine. The device further includes a monitor for monitoring the first assistance, and a second power supply for electrically powering a second winding of the rotary machine to provide second assistance in accelerating the gas generator if the monitor observes that the first assistance is insufficient.

The invention is in the field of engine building technology and may be used in space technology or aviation. Liquid-propellant rockets with Laval nozzles are well known, and they have the following insufficiencies: (1) high fuel consumption rates, which lead to increased dimensions and engine weight and boosters; (2) a relatively low combustion efficiency, because the low mass of the combustion products are emitted into the environment; (3) the large length of the de Laval nozzles with increased expansion ratios increase the dimensions and the engine weight; (4) use of high temperature rocket propellants—combustion products—in the camera and de Laval nozzle. These insufficiencies suppress using liquid-propellant rockets in space technology. The goal of the invention is decreasing the influence of these insufficiencies and obtaining an engine with improved efficiency. The goal is achieved with the creation of an engine with the subsonic discharge of combustion products and the creation of a simple nozzle construction.

The present invention relates to an optical clear resin and a method for producing a liquid optical clear photo-curable adhesive.

A surface machining method for a single crystal SiC substrate, including: a step of mounting a grinding plate which includes a soft pad and a hard pad sequentially attached onto a base metal having a flat surface, a step of generating an oxidation product by using the grinding plate, and a step of grinding the surface while removing the oxidation product, wherein abrasive grains made of at least one metallic oxide that is softer than single crystal SiC and has a bandgap are fixed to the surface of the hard pad.

The present invention relates to novel thermoplastic polyurethane (TPU) compositions that contain linear monohydric alcohols. The present invention provides for TPU compositions which may be applied at relatively low temperatures, but upon activation (e.g., activation by ultraviolet light), exhibits higher temperature and melt resistance.

A multi-axis passenger-carrying aircraft comprises: an electrical system; a heat exchange system; a cabin; and an accommodating compartment arranged inside the cabin; wherein the electrical system is arranged inside the accommodating compartment, and wherein the heat exchange system comprises at least an air inlet communicated with the exterior of the cabin, an air outlet communicated with the accommodating compartment, and a cooler with an air inlet end communicated with the air inlet and an air outlet end communicated with the air outlet. In operation, air outside the aircraft may enter the heat exchange system via the air inlet and the cooler via the air inlet end to be cooled by the cooler. The cooled air may be discharged via the air outlet end and then enter the accommodating compartment via the air outlet, providing cool air to the accommodating compartment and dissipating heat from the electrical system.

Multi-axis passenger-carrying aircraft is provided, including: a heat exchange system; a cabin; and a passenger accommodating compartment arranged inside the cabin; wherein the electrical system is arranged inside the passenger accommodating compartment, and wherein the heat exchange system at least includes an air inlet in communication with the exterior of the cabin, an air outlet in communication with the passenger accommodating compartment, and a cooling and heating device with an air inlet end communicated with the air inlet and an air outlet end communicated with the air outlet. In operation, air outside the aircraft may enter the heat exchange system via the air inlet and the cooling and heating device via the air inlet end to be cooled or heated by the cooling and heating device. The air after heat exchange may be discharged via the air outlet end and enter the passenger accommodating compartment via the air outlet.

An assembly comprising a duct (1) for passing a flow of cryogenic fluid, and a valve (2); the assembly being characterized in that the duct (1) includes an interface for inserting the valve, the interface forming an internal abutment (51) and an external abutment (52);the valve (2) being configured in such a manner as to be inserted into said insertion interface by sliding, the valve (2) comprising a valve body (3) presenting a first end (31) and a second end (32), the valve body (3) being adapted to be bolted in said insertion interface in such a manner that the first end (31) and the second end (32) come into abutment respectively against the internal abutment (51) and against the external abutment (52), the assembly including an internal sealing element (61) arranged between the internal abutment (51) and the first end (31), and an external sealing element (62) arranged between the external abutment (52) and the second end (32).

A rotary valve mechanism includes a stator valve member furnished with one of either a dome-shaped high-pressure recess area made of a polymer or a high-pressure flow path made of metal, and a rotor valve member furnished with the other of either the dome-shaped high-pressure recess area made of a polymer or the high-pressure flow path made of metal, and seals a high-pressure region being the high-pressure flow path communicated with the dome-shaped high-pressure recess area and is disposed adjoining the stator valve member such as to isolate the high-pressure region from its low-pressure surrounding environs.

It is interesting that the Greek Prime Minister, Alexis Tsipras, summons the very real fact his nation invented democracy to bolster his government’s argument for a favourable solution to the debt crisis wracking its citizens.

There are few who aren’t familiar with the classic works of Jane Austen. Pride and Prejudice, Sense and Sensibility, Emma, Persuasion, the list goes on.

What better way to start your special event than a drive along the tree-lined carriageway to Winslowe House?

Covid-19 propels push for federal cannabis relief; advocates see parallel with Prohibition Major political and social changes often seem impossible until they happen. The Supreme Court's 2015 ruling recognizing gay marriage surprised most observers, including those who had been working toward the goal for decades.…

“I am not a number. I am a free man!” I’m afraid not, you’re a number… when it comes to credit scoring anyway. The famous cry for help of the eponymous Prisoner from the cult 1960s TV show of the 1960, could have been written for today’s world of mass computer assessed finance.

IT’S the “life-saving” organisation that is slowly emerging from the shadows.

A FUNDRAISING page has been launched to help a Hedge End man and his wife after the helicopter they were sightseeing in crashed into the Grand Canyon.

FORMER Hampshire star Glenn Maxwell blasted 88 off only 39 balls as Australia romped to the highest team total in cricket World Cup history.

Former Hampshire star Glenn Maxwell hit the second-fastest century in Cricket World Cup history as Australia beat Sri Lanka by 64 runs to book a quarter-final place.

Kevin Pietersen marked his long-awaited return to domestic cricket with 170 for Surrey against Oxford MCCU.

TELEVISION presenter Piers Morgan has aimed a dig at a BBC Radio Solent journalist today over former Hampshire Cricket star Kevin Pietersen's exclusion from the England squad.

All the photos from Saints' 1-0 victory against Crystal Palace, as Sadio Mane's late goal decides the match.

HARRY Foyle stole the show with two best-yet individual performances as St Cross Symondians thrashed hapless New Milton by 162 runs to move fourth in the ECB Southern Premier Division.

A HAMPSHIRE Cricket League match will start at 8.30am on Saturday so players can watch England’s World Cup quarter-final against Sweden.