cher

Japanese researchers want to give granny a robotic monkey tail

Japanese researchers at Keio University have unveiled a robotic tail that has been designed to be worn by elderly people who struggle to maintain their balance.




cher

COVID-19 has ravaged ride-hailing companies, but an industry watcher says the crisis could make Uber stronger (UBER)

  • While ride-hailing has suffered from the impact of COVID-19, Uber is in a good position to survive the crisis, three analysts who cover the company told Business Insider.
  • Uber is in no danger of running of out money anytime soon, said Mark Mahaney, a managing director at RBC Capital Markets.
  • And a series of cost-cutting moves should make the company profitable by next year, said Dan Ives, a managing director of equity research at Wedbush Securities.
  • Uber's food-delivery service, Uber Eats, gives the company an advantage over ride-hailing competitors, since it allows homebound consumers to keep using its app, said Tom White, a senior research analyst at DA Davidson.
  • Are you a current or former Uber employee? Do you have an opinion about what it's like to work there? Contact this reporter at mmatousek@businessinsider.com. You can also reach out on Signal at 646-768-4712 or email this reporter's encrypted address at mmatousek@protonmail.com.
  • Visit Business Insider's homepage for more stories.

The ride-hailing industry has taken a major hit from COVID-19 as potential customers remain confined to their homes, but Uber is in a good position to survive the crisis, three analysts who cover the company said.

"Their business model will be intact on the other side of this," said Dan Ives, a managing director of equity research at Wedbush Securities.

A strong cash reserve will help. After ending the first quarter with $9 billion in cash and short-term investments, Uber has the resources to survive a scenario in which the prevalence of COVID-19 and its effect on consumer behavior last for the next two years, said Mark Mahaney, a managing director at RBC Capital Markets.

On Thursday, Uber disclosed its first-quarter financial results, reporting an adjusted loss of $2.9 billion on revenue of $3.5 billion during the first three months of this year. Uber CEO Dara Khosrowshahi said on a call with analysts that the ride-hailing company would cut $1 billion in fixed costs. The company has recently removed its food-delivery service — Uber Eats — from eight unprofitable markets, folded its electric bike and scooter business into Lime (Uber recently led a $170 million investment round in the company), and announced it will lay off about 14% of its workforce.

Those moves should help Uber become profitable in 2021 (the company predicted in February that it would turn a profit by the end of this year), Ives said. Uber's management, which had struggled in the wake of the company's 2019 IPO, has performed well in the current crisis by being transparent with investors and quickly moving to reduce expenses, Ives said. Investors signaled their approval of the company's strategy by sending shares up as much as 8% in after-hours trading on Thursday.

Uber Eats was one of the highlights of the company's first-quarter results, said Tom White, a senior research analyst at DA Davidson, as gross bookings grew 52% from the first quarter of 2019 to $4.7 billion. Eats gives Uber an advantage over ride-hailing competitors that don't have a similar service, as it allows the company to keep homebound consumers using its app, White said. Even after the toll of COVID-19 begins to subside, demand for online food delivery could see continued growth, he added.

But there are still challenges ahead for Uber. The company said rides fell by as much as 80% in April, and Ives projects that 30% of the customers for gig-economy companies like Uber, Airbnb, and Lyft won't use a ride-hailing service until there's a vaccine for COVID-19. Yet the pandemic could leave Uber better off in the long run, White said.

"I saw and heard enough [during Uber's first-quarter earnings call] that makes it harder and harder for me to think that these guys don't emerge from this pandemic probably in a stronger competitive position and a healthier and leaner operating position," he said.

Are you a current or former Uber employee? Do you have an opinion about what it's like to work there? Contact this reporter at mmatousek@businessinsider.com. You can also reach out on Signal at 646-768-4712 or email this reporter's encrypted address at mmatousek@protonmail.com.

SEE ALSO: Elon Musk's theater of the absurd is a sign of the times for tech

Join the conversation about this story »

NOW WATCH: Why Pikes Peak is the most dangerous racetrack in America




cher

Dua Lipa for Bernie? Cher for Biden? Here’s where the celebrities stand on Super Tuesday.

Stars tweeted their support for their candidates of choice leading up to one of the most significant days in the Democratic primary race.




cher

A number cruncher told the truth. He became his country’s public enemy No. 1.

Andreas Georgiou offered an honest accounting of Greece’s financial situation. He’s still paying for it.




cher

Books are key to the future: an interview with Wade and Cheryl Willis Hudson

We hear a lot about diversity and inclusion these days, often as it relates to books for young readers. Just as publishing for children and teens has evolved over the years, so has adults’ perception of youth and what is appropriate for them.




cher

How Founders and CEOs Can Raise Early Checks (With Pavel Cherkashin)

I’m excited to speak with Pavel Cherkashin in today’s episode of the How To CEO podcast!. Pavel is a co-founder and managing partner at Mindrock Capital. Pavel is also a managing partner at GVA Capital. I spoke with him about what founders and CEOs need to know about raising early checks. When Should Founders Try […]

The post How Founders and CEOs Can Raise Early Checks (With Pavel Cherkashin) appeared first on ReadWrite.




cher

Univ of Pittsburg Researcher, China Native, Dr. Bing Liu, “On the verge” of COVID19 Breakthrough Is Murdered…Alleged Gunman, Hao Gu, Kills Himself

The following article, Univ of Pittsburg Researcher, China Native, Dr. Bing Liu, “On the verge” of COVID19 Breakthrough Is Murdered…Alleged Gunman, Hao Gu, Kills Himself, was first published on 100PercentFedUp.com.

A 37-year-old China native and "outstanding researcher" at the University of Pittsburgh...

Continue reading: Univ of Pittsburg Researcher, China Native, Dr. Bing Liu, “On the verge” of COVID19 Breakthrough Is Murdered…Alleged Gunman, Hao Gu, Kills Himself ...




cher

Lysine Acetylation Is a Highly Abundant and Evolutionarily Conserved Modification in Escherichia Coli

Junmei Zhang
Feb 1, 2009; 8:215-225
Research




cher

The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase [Glycobiology and Extracellular Matrices]

Bacterial biofilms are cellular communities that produce an adherent matrix. Exopolysaccharides are key structural components of this matrix and are required for the assembly and architecture of biofilms produced by a wide variety of microorganisms. The human bacterial pathogens Escherichia coli and Salmonella enterica produce a biofilm matrix composed primarily of the exopolysaccharide phosphoethanolamine (pEtN) cellulose. Once thought to be composed of only underivatized cellulose, the pEtN modification present in these matrices has been implicated in the overall architecture and integrity of the biofilm. However, an understanding of the mechanism underlying pEtN derivatization of the cellulose exopolysaccharide remains elusive. The bacterial cellulose synthase subunit G (BcsG) is a predicted inner membrane–localized metalloenzyme that has been proposed to catalyze the transfer of the pEtN group from membrane phospholipids to cellulose. Here we present evidence that the C-terminal domain of BcsG from E. coli (EcBcsGΔN) functions as a phosphoethanolamine transferase in vitro with substrate preference for cellulosic materials. Structural characterization of EcBcsGΔN revealed that it belongs to the alkaline phosphatase superfamily, contains a Zn2+ ion at its active center, and is structurally similar to characterized enzymes that confer colistin resistance in Gram-negative bacteria. Informed by our structural studies, we present a functional complementation experiment in E. coli AR3110, indicating that the activity of the BcsG C-terminal domain is essential for integrity of the pellicular biofilm. Furthermore, our results established a similar but distinct active-site architecture and catalytic mechanism shared between BcsG and the colistin resistance enzymes.




cher

Thwarting Poachers: Part 2

Researcher: Thomas Snitch, University of Maryland
Description: Thomas Snitch talks about nabbing poachers with math.
Audio files: podcast-mom-poaching-1.mp3 and podcast-mom-poaching-2.mp3




cher

L.A. County's biodiversity is on the map, thanks to UCLA researchers

Located in a global hotspot for biodiversity, Los Angeles County is home to more than 4,000 distinct species of plants and animals, including 52 endangered species - more than any county outside of Hawaii. And with 1 million animal and plant species facing extinction due to human activity, according to the United Nations, efforts to better understand the factors that shape biodiversity in Los Angeles could help shape global conservation efforts.




cher

CBD News: The world needs transformative change if life on Earth is to be safeguarded and people are to continue to receive the services and benefits that nature provides, according to a new report from an international team of leading researchers.




cher

Dartmouth's Katherine Mirica wins National Teacher-Scholar Honor

(Dartmouth College) Annual award supports the research and teaching careers of talented young faculty in the chemical sciences.




cher

The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase [Glycobiology and Extracellular Matrices]

Bacterial biofilms are cellular communities that produce an adherent matrix. Exopolysaccharides are key structural components of this matrix and are required for the assembly and architecture of biofilms produced by a wide variety of microorganisms. The human bacterial pathogens Escherichia coli and Salmonella enterica produce a biofilm matrix composed primarily of the exopolysaccharide phosphoethanolamine (pEtN) cellulose. Once thought to be composed of only underivatized cellulose, the pEtN modification present in these matrices has been implicated in the overall architecture and integrity of the biofilm. However, an understanding of the mechanism underlying pEtN derivatization of the cellulose exopolysaccharide remains elusive. The bacterial cellulose synthase subunit G (BcsG) is a predicted inner membrane–localized metalloenzyme that has been proposed to catalyze the transfer of the pEtN group from membrane phospholipids to cellulose. Here we present evidence that the C-terminal domain of BcsG from E. coli (EcBcsGΔN) functions as a phosphoethanolamine transferase in vitro with substrate preference for cellulosic materials. Structural characterization of EcBcsGΔN revealed that it belongs to the alkaline phosphatase superfamily, contains a Zn2+ ion at its active center, and is structurally similar to characterized enzymes that confer colistin resistance in Gram-negative bacteria. Informed by our structural studies, we present a functional complementation experiment in E. coli AR3110, indicating that the activity of the BcsG C-terminal domain is essential for integrity of the pellicular biofilm. Furthermore, our results established a similar but distinct active-site architecture and catalytic mechanism shared between BcsG and the colistin resistance enzymes.




cher

SED on handling of teachers' misconduct




cher

SED on principals' handing of complaints against teachers' misconduct




cher

SED on class resumption and complaints against teachers




cher

New AI enables teachers to rapidly develop intelligent tutoring systems

(Carnegie Mellon University) Intelligent tutoring systems have been shown to be effective in helping to teach certain subjects, such as algebra or grammar, but creating these computerized systems is difficult and laborious. Now, researchers at Carnegie Mellon University have shown they can rapidly build them by, in effect, teaching the computer to teach.




cher

ASU professor recognized nationally with Camille Dreyfus Teacher-Scholar Award

(Arizona State University) Gary Moore, assistant professor in ASU's School of Molecular Sciences and the Biodesign Institute's Center for Applied Structural Discovery has just been named one of 14 young faculty nationwide to be honored with a 2020 Camille Dreyfus Teacher-Scholar Award by the Camille and Henry Dreyfus Foundation.




cher

Researchers Answer a Diversity Puzzle: Why Chinese Americans but not Indian Americans are Underrepresented in Leadership Positions

Thursday, February 20, 2020 - 11:15

New studies identify the boundary and causes of the “Bamboo Ceiling”




cher

Researchers have found accumulation of gene mutations in chronic Graft-versus-host disease

(University of Helsinki) Mutations in white blood cells can contribute to abnormal immune profile after hematopoietic stem cell transplantation.




cher

University of Houston researcher developing device to treat babies with blood disorders

(University of Houston) A University of Houston biomedical researcher is developing a new device to treat babies with blood disorders, because current technology is designed for adults. The ability to perform lifesaving leukapheresis safely and effectively in these most vulnerable pediatric patients will significantly increase their access to highly effective cell-based therapies.




cher

George Mason University researchers and World Bank launch web portal for hospitals

(George Mason University) The team's work supports evidence-based decision making, informed by models, to rethink and facilitate hospital operations during the pandemic.




cher

Software flaws often first reported on social media networks, PNNL researchers find

(DOE/Pacific Northwest National Laboratory) Software vulnerabilities are more likely to be discussed on social media before they're revealed on a government reporting site, a practice that could pose a national security threat, according to computer scientists at Pacific Northwest National Laboratory.




cher

Researcher developing cutting-edge solution for wind energy

(University of Massachusetts Lowell) A UMass Lowell researcher investigating how to identify damage in wind turbines before they fail has received $1.4 million to develop a solution.




cher

UBC researchers establish new timeline for ancient magnetic field on Mars

(University of British Columbia) Mars had a global magnetic field much earlier -- and much later -- than previously known. Analysis of new satellite data found clear evidence of a magnetic field coming from a lava flow that formed less than 3.7 billion years ago, half a billion years after many people thought the Martian dynamo had ceased. The researchers also detected low-intensity magnetic fields over the Borealis Basin, believed to be one of the oldest features on Mars.




cher

Free use of Kudos Pro to help researchers keep communicating during pandemic disruption

(Kudos Innovations Ltd) Kudos helps researchers maximize reach and visibility of research by opening up Kudos Pro. The platform helps showcase work to a range of target audiences, supporting researchers in fields where conferences have been cancelled -- and those with COVID-19-relevant work that needs rapid communication. Over 2,000 researchers have already signed up.




cher

QUT researchers to head to Antarctica in preservation efforts

(Queensland University of Technology) Robots that fly, swim and drive are being designed and built by internationally renowned Australian scientists from QUT.




cher

FSU researchers study Gulf of Mexico in international collaboration

(Florida State University) Florida State University and partner universities investigated current baseline conditions in the southern Gulf to create a series of maps and guides that detail the distribution of carbon, nitrogen and the carbon-14 isotope.




cher

Marketing claims for infant formula should be banned, argue researchers

Current regulations do not effectively prevent potentially misleading claims, says Imperial scientists




cher

UCSF expert to offer 'confessions of unfocused researcher' on road to better care

(American Geriatrics Society) The American Geriatrics Society (AGS) and AGS Health in Aging Foundation today announced that Alexander K. Smith, MD, MPH, an associate professor of medicine at UCSF and one of geriatrics' most influential rising researchers and advocates, will be honored with the 2020/2021 Thomas and Catherine Yoshikawa Award for Outstanding Scientific Achievement in Clinical Investigation.




cher

AGS honors society's first pharmacist president with prestigious Nascher/Manning award

(American Geriatrics Society) The American Geriatrics Society (AGS) will this year honor past AGS President Todd Semla, PharmD, MS, AGSF, with the prestigious Nascher/Manning Award, given biannually at the AGS Annual Scientific Meeting (#AGS21, to be held next year May 13-15 in Chicago, Ill., following the cancellation of the AGS 2020 Annual Scientific Meeting due to COVID-19).




cher

Researchers present a microbial strain capable of massive succinic acid production

(The Korea Advanced Institute of Science and Technology (KAIST)) A research team led by Distinguished Professor Sang-Yup Lee reported the production of a microbial strain capable of the massive production of succinic acid with the highest production efficiency to date. This strategy of integrating systems metabolic engineering with enzyme engineering will be useful for the production of industrially competitive bio-based chemicals.




cher

How changes to drug prohibition could be good for the UK—an essay by Molly Meacher and Nick Clegg




cher

Risks of duloxetine for stress incontinence outweigh benefits, say researchers




cher

Cow’s milk allergy guidelines are not evidence based and are beset by conflicts of interest, researchers warn




cher

Dream Catcher

Here you are, In a long, low, valley, On a horse, under sweltering sky. A single trail runs East to West, As far as the eye can see. The sheep-skin bags, Slung low off the saddle, Are empty. Bandits rode into town last week, And made off with a couple of dreams, Now you must […]




cher

200 Hour Yoga Teacher Training in Rishikesh

Do you want to become a certified Yoga Teacher? Just join our 200 Hour Yoga Teacher Training in Rishikesh and become a certified Yoga Teacher.




cher

O's pitchers welcoming high-tech revolution

Like so many pitchers in Major League camps, Orioles hurlers have extra sets of eyes on them this spring. The Edgertronic cameras, perched on tripods, are set about a stride's length beyond the backfield bullpen mounds at the club's Ed Smith Stadium complex, as conspicuous as the coaches standing cross-armed behind them.




cher

Rule 5 pick Joe back in catcher's gear with Reds

Utility player and Rule 5 selection Connor Joe has been working with the catchers since Reds Spring Training opened. What makes that a little more interesting is that Joe has never caught a game professionally.




cher

D-backs pair among best starting pitcher duos

Most Major League teams still use a five-man starting rotation, but it takes a lot more pitchers than that to make it through a 162-game season. It certainly helps to have a potent one-two punch at the top of the rotation.




cher

'Campfire drill' helps pitchers, catchers bond

After seeing improved communication between pitchers and catchers last year, the "campfire" drill was put back on the D-backs' schedule and took place Friday at Salt River Fields.




cher

What math professors and k-12 teachers think of each other

By Michael Pershan, St. Ann’s School I. What do primary/secondary math educators think of the teaching that happens in colleges? And — the other way around — what do mathematics professors think of primary and secondary math teaching? I’m nearing … Continue reading




cher

Raytheon nabs $19M for RAM missiles, GMLS launchers

Raytheon Missile Systems was awarded a $19 million contract modification to exercise options for Navy Rolling Airframe Missile and Guided Missile Launching Systems, according to the Department of Defense.




cher

Researcher remembered for contributions to dentistry succumbs to COVID-19 complications

Dr. Leo M. Sreebny, Ph.D., who had a long and distinguished career in academia as a professor of dentistry and researcher, particularly in issues related to saliva and dry mouth, died April 5 from complications of COVID-19 at age 98.




cher

UCLA dental school researchers create nanoparticle that could improve bone defect treatment

A team of researchers at the University of California, Los Angeles School of Dentistry has developed a nanoparticle that could improve treatment for bone defects.




cher

Researchers discover microbe that could control spread of malaria

A microbe found in mosquitoes that appears to block malaria could be used to control spread of the disease in humans, according to researchers in Kenya and Britain.




cher

British researchers evaluate asthma, COPD drug for COVID-19

Interferon beta, a drug originally developed to treat chronic obstructive pulmonary disease, or COPD, is being explored as a possible cure for the severe lung infections caused by COVID-19, media reports confirmed Monday




cher

Teacher's Role in a Successful Behavior Plan

Over the last few years I have been very busy working with teachers to create individualized behavior plans for several different elementary school students. There have been amazingly successful plans where some of the most significant behavior problems in the school have turned it around. Children who made daily trips to the office are only there now to receive praise from the administration. Teachers previously brought to tears from the behaviors have stopped me in the hall to say "Oh my goodness, he's like a different kid!" Students who were close to being sent to a day placement school are now succeeding in a regular classroom. It's very encouraging if I focus on those students. However, there have also been some plans that have been revised and revised and revised and the student is still struggling and the teacher is still severely frustrated. I have been reflecting on why some behavior plans work and others don't. Of course one of the biggest factors is the student. All students are different and the motivation for the misbehavior or lacking skill is different in each student. While this is important to consider, this particular article does not focus on this. I'm going to focus today on the teacher's role in making the behavior plan successful.




  • Focus on the Positive!!! The behavior plans that have had the most dramatic success are plans that allow the teacher to focus on the positive. Classroom consequences are still in place, but are not connected to the plan. Here is an example: Johnny's teachers will offer positive reinforcement frequently in the classroom by giving Johnny a “warm fuzzy” pom pom when he is caught engaging in a desired behavior. Johnny will chose the bag to keep the “warm fuzzies” in and carry the bag with him to every class. Once the bag is full, he receives an immediate reward. There is no limit to how many “warm fuzzies” he can earn in a day. He does not loose “warm fuzzies” that he has already earned. All teachers and staff who work with Johnny can give him “warm fuzzies” for his bag. This plan works because Johnny who was used to receiving a lot of negative feedback, is now getting positive attention frequently throughout the day. He receives something tangible (the warm fuzzy) that he can put into his bag. This begins to change his perception of himself, which changes his behavior, which changes his teacher's perception of him, which can potentially change his future. Plans that offer positive rewards completely separate from the classroom consequences seem to have the most significant effects.



  • Be Consistent. Teachers who are able to be consistent and are able to follow through every time have the most success with the plan. Oppositional children are excellent at pushing limits to see how far they can push. Consistent teachers have more success because they don't offer the wiggle room.



  • Be Flexible. This is not the opposite of being consistent. This is having flexibility in your expectations and stating them upfront. If the student was able to behave like everyone else in the class she would be. She may need some flexibility in some areas. For example you may need to have area for her to work in the classroom for times she needs to cool down and get away from a stimulus. The teacher may need to allow her extra time to finish projects if it is the transition that sets her off. Being flexible and willing to make acceptable changes for the student sets everyone up for success.



  • Remember that all students are different. The behaviors may be exactly the same as a student you had two years ago. However, that doesn't mean that the motivation for the behavior or the lacking skills are the same. What works for one student may not work for the next. That is the reason for the individualized plan. I strongly recommend doing a formal Functional Behavioral Assessment and a Behavior Intervention Plan.

Teachers have a HUGE part in making the Behavior Plan sucessful. It is the teacher who has to follow through and implement it consistently every day. It is the teacher who has to push forward even when it appears it isn't working at first. It is the teacher who has a tremendous positive impact on the student when the behavior starts turning around. It is the teacher who does the work to change lives!




cher

Introducing wolves leads to fewer wildland coyotes, researchers find

As the population of gray wolves expands across the northern United States, researchers are finding a surprising side-effect: Their presence appears to lead to a reduction in the coyote population.