A sea of red swept the capitals of North and South Carolina on Wednesday, as thousands of teachers turned out to demand higher pay and more school funding.

North Carolina teachers had press conferences in seven locations across the state to criticize education spending levels.

North Carolina officials' switch in reading-test vendors just weeks before the new school year got underway is spotlighting the often murky process of contracts and procurements for K-12 services.

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.

A $12.2 million dollar grant from the state Department of Public Instruction will go to a program based at North Carolina State University to provide additional training literacy training to teachers in 16 high-needs districts across the state.

U.S. Ed Secretary DeVos has approved plans for 46 states, plus the District of Columbia and Puerto Rico. Still waiting: California, Florida, Oklahoma, and Utah.

This fall, five South Carolina high schools will offer an aerospace curriculum to develop the next generation of aviation technology talent in a state where officials say the industry is thriving.

A budget amendment will provide funds to develop a teacher incentive program in rural areas.

This Quality Counts 2019 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.

U.S. Secretary of Education Betsy DeVos has greenlighted two more Every Student Succeeds Act plans from Virginia and South Carolina. That brings the grand total of states with approved plans to 39, plus the District of Columbia and Puerto Rico.

A program that lets retired teachers keep working while collecting retirement benefits is set to expire at the end of the month.

A sea of red swept the capitals of North and South Carolina on Wednesday, as thousands of teachers turned out to demand higher pay and more school funding.

This Quality Counts 2020 Highlights Report captures all the data you need to assess your state's performance on key educational outcomes.

Players and coaches said they had a good time playing in the Queen City.

South Carolina a unanimous No. in women's AP Top 25 after 2 wins to open repeat bid; Stanford, Oregon crack rankings.

The Gamecocks earned a hard-fought six-point win over Michigan in Las Vegas to open the season and beat then-No. 9 North Carolina State on Sunday by 14. The two victories made the defending champions a unanimous choice from the 31-member national media panel. In the preseason poll, No. 2 UConn got two first-place votes and No. 3 USC one.

South Carolina football landed 21st in the latest CFP bracket. Here’s the College Football Playoff for the newly ranked No. 23 Gamecocks.

α-Neurexins are essential and highly expressed presynaptic cell-adhesion molecules that are frequently linked to neuropsychiatric and neurodevelopmental disorders. Despite their importance, how the elaborate extracellular sequences of α-neurexins contribute to synapse function is poorly understood. We recently characterized the presynaptic gain-of-function phenotype caused by a missense mutation in an evolutionarily conserved extracellular sequence of neurexin-3α (A687T) that we identified in a patient diagnosed with profound intellectual disability and epilepsy. The striking A687T gain-of-function mutation on neurexin-3α prompted us to systematically test using mutants whether the presynaptic gain-of-function phenotype is a consequence of the addition of side-chain bulk (i.e., A687V) or polar/hydrophilic properties (i.e., A687S). We used multidisciplinary approaches in mixed-sex primary hippocampal cultures to assess the impact of the neurexin-3α^A687 residue on synapse morphology, function and ligand binding. Unexpectedly, neither A687V nor A687S recapitulated the neurexin-3α A687T phenotype. Instead, distinct from A687T, molecular replacement with A687S significantly enhanced postsynaptic properties exclusively at excitatory synapses and selectively increased binding to neuroligin-1 and neuroligin-3 without changing binding to neuroligin-2 or LRRTM2. Importantly, we provide the first experimental evidence supporting the notion that the position A687 of neurexin-3α and the N-terminal sequences of neuroligins may contribute to the stability of α-neurexin–neuroligin-1 trans-synaptic interactions and that these interactions may specifically regulate the postsynaptic strength of excitatory synapses.

A special committee has until January 15 to finalize the design, location and funding for a monument that will be erected on the lawn of the South Carolina State House

Once the first primate made a break, the 42 others followed suit in a simple case of monkey-see, monkey-do

An increasing number of people in France espouse a clothing-free lifestyle

U.S. Senator Chriss Coons and Ambassador to Australia Carolina Kennedy recently visited New Castle's historic sites.

The Delaware Emergency Management Agency (DEMA) and the Delaware State Fire School have deployed a Swift Water Rescue Team (SWRT) to North Carolina on Saturday under the Emergency Management Assistance Compact (EMAC) to support response and recovery efforts following the devastation caused by Hurricane Helene late last week.

Birders and organized labor dominated a recent public comment period, while beach towns were mostly mum. The Bureau of Ocean Energy Management will now consider the input ahead of an anticipated auction this spring.

Karolinska Institutet is a medical university encompassing 21 departments distributed across three departmental or campus groups. Pharmacological research has a long and successful tradition at the institute with a multitude of seminal findings in the areas of neuronal control of vasodilatation, cardiovascular pharmacology, neuropsychopharmacology, receptor pharmacology, and pharmacogenomics that resulted in, among many other recognitions, two Nobel prizes in Physiology and Medicine, one in 1970 to Ulf von Euler for his discovery of the processes involved in storage, release, and inactivation of neurotransmitters and the other in 1982 to Sune Bergström and Bengt Samuelsson for their work on prostaglandins and the discovery of leukotrienes. Pharmacology at Karolinska Institutet has over the last decade been ranked globally among the top 10 according to the QS World University Ranking. With the Department of Physiology and Pharmacology now celebrating its 75-year anniversary, we wanted to take this as an opportunity to showcase recent research achievements and how they paved the way for current activities at the department. We emphasize examples from preclinical and clinical research where the dpartment's integrative environment and robust infrastructure have successfully facilitated the translation of findings into clinical applications and patient benefits. The close collaboration between preclinical scientists and clinical researchers across various disciplines, along with a strong network of partnerships within the department and beyond, positions us to continue leading world-class pharmacological research at the Department of Physiology and Pharmacology for decades to come.

Venomous Blue Sea Dragons are washing up on the sandy shores of the Outer Banks in North Carolina, and National Park officials advise to admire them from a distance.

Jul 9, 2024

Those harboring doubts about the viability of nuclear non-proliferation ought to consider the lessons of the past 75 years. Even if it proves impossible to contain this catastrophically destructive technology completely, a world with fewer nuclear-armed states is exponentially safer than one with many of them.

Mar 5, 2024

Joseph Nye considers lessons from his own work on preventing the spread of nuclear technology in the 1970s.

Dr Aluvihare

IWMI's Marie-Charlotte Buisson spoke to Radio Canada about the particular challenges of solar-powered irrigation.

The post The challenges associated with the proliferation of solar irrigation pumps first appeared on International Water Management Institute (IWMI).

Manchester : Manchester University Press, [2020]

New York; Oxford : Berghahn Books, [2023]

Manchester : Manchester University Press, [2017]

Kaufman, Caroline, author

When working through the early stages of a product design, it's common that labels for objects and actions emerge organically. No one is overly concerned about making these labels consistent (yet). But if this proliferation of terms doesn't get reined in early, both product design and strategy get harder.

Do we call it a library, a folder, a collection, a workspace, a section, a category, a topic? How about a document, page, file, entry, article, worksheet? And.. what's the difference? While these kinds of decisions might not be front and center when working out designs for a product or feature, they can impact a lot.

For starters, having clear definitions for concepts helps keep teams on the same page. When engineering works on implementing a new object type, they're aligned with what design is thinking, which is what the sales team is pitching potential customers on. Bringing a product to life is hard enough, why complicate things by using different terms for similar things or vice versa?

Inconsistent terms are obviously also a comprehension issue for the people using our products. "Here's it's called a Document, there it's called an Article. Are those the same?" Additionally, undefined terms often lead to miscellaneous bins in our user interfaces. "What's inside Explore?" When the definition of objects and actions isn't clear, what choice do we have but to drop them into vague sounding containers like Discover?

The more a product gets developed (especially by bigger teams) the more things can diverge because people's mental model of what terms mean can vary a lot. So it's really useful to proactively put together a list of the objects and actions that make up an application and draft some simple one-liner definitions for each. These lists almost always kick off useful high-level discussions within teams on what we're building and for who. Being forced to define things requires you to think them through: what is this feature doing and why?

And of course, consistent labels also ease comprehension for users. Once people learn what something means, they'll be able to apply that knowledge elsewhere -instead of having to contend with mystery meat navigation.

Karolina Muchova has eliminated two-time U.S. Open champion Naomi Osaka 6-3, 7-6 (5) in the second round at Flushing Meadows

Jessica Pegula has shrugged off a sluggish start and come back from a set and a break down at the U.S. Open to defeat Karolina Muchova 1-6, 6-4, 6-2 for a berth in her first Grand Slam final

These products are slated for launch in the fourth quarter of the fiscal year.