antibody

Coronavirus: Is UK standard for antibody tests TOO high?

A test made by Chinese manufacturer Wondfo was found by US researchers to be just 3.2 per cent less sensitive than the machine used to evaluate testing kits at the University of Oxford.




antibody

New coronavirus antibody blood test being used by the US Navy can deliver results in just 15 MINUTES

The test, made by California-based made by Global WholeHealth Partners Corp, can reportedly deliver a positive result in just 15 minutes with nearly 99% accuracy.




antibody

Coronavirus: Discovery of antibody to stop human cell infection

Scientists say they've discovered an antibody that blocks infection by SARS-CoV-2, the coronavirus behind the current global health crisis.




antibody

Abbott's Covid-19 Lab-based Antibody Tests to be Available in India by End of May

Antibody testing is an important step to tell if someone has been previously infected. It will provide more understanding of the virus.




antibody

Study Suggests Abbott Covid-19 Antibody Test Highly Likely to Give Correct Results

Antibody tests can tell whether a person has ever been infected and are considered crucial in efforts to get Americans back to work safely as the presence of antibodies to the virus indicate possible immunity to future infection.




antibody

Israel claims 'significant breakthrough' in developing antibody against coronavirus

Jerusalem, May 05: Israeli Defence Minister Naftali Bennett has said that scientists at the country's main biological research institute have made a "significant breakthrough" in developing an antibody to the novel coronavirus, as the researchers wrapped up the development phase and moved




antibody

'Significant breakthrough' by Israeli lab in developing antibody against coronavirus

Scientists at Israel's Institute for Biological Research (IIBR) have wrapped up the development phase and moved to patent and mass produce the potential treatment.




antibody

[ASAP] Complementary Methods for de Novo Monoclonal Antibody Sequencing to Achieve Complete Sequence Coverage

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00223




antibody

Simultaneous detection of plant growth regulators jasmonic acid and methyl jasmonate in plant samples by a monoclonal antibody-based ELISA

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00203H, Paper
Minghui Yi, Linchuan Zhao, Kang Wu, Chang Liu, Diandian Deng, Kang Zhao, Jianguo Li, Anping Deng
Methyl jasmonate (MeJA) and its free-acid form, jasmonic acid (JA), collectively referred to as jasmonates (JAs), are natural plant growth regulators that are widely present in higher plants.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

Antibody free ELISA-like assay for the detection of transcription factors based on double-stranded DNA thermostability

Analyst, 2020, 145,3339-3344
DOI: 10.1039/C9AN02631B, Paper
Yue Sun, Zhiyan Li, Choiwan Lau, Jianzhong Lu
Transcription factors (TFs) play critical roles in gene expression regulation and disease development. Herein we report a chemiluminescence assay for the detection of transcription factor based on double-stranded DNA thermostability.
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

[ASAP] Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via <sup>15</sup>N Direct Detection Nuclear Magnetic Resonance

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00231




antibody

Protein labeling approach to improve lysosomal targeting and efficacy of antibody–drug conjugates

Org. Biomol. Chem., 2020, 18,3229-3233
DOI: 10.1039/D0OB00265H, Communication
Ying Han, Yifan Da, Mingjia Yu, Yaping Cheng, Xin Wang, Jiale Xiong, Guoying Guo, Yan Li, Xianxing Jiang, Xiaoqing Cai
An anti-EGFR nanobody was labeled at the C-terminus with a lysosome-sorting NPGY (Asn-Pro-Gly-Tyr) motif via sortase-mediated ligation to enhance the clathrin-mediated endocytosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

Cytotoxic payloads for antibody--drug conjugates / edited by David E. Thurston and Paul J.M. Jackson

Online Resource




antibody

[ASAP] Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4

ACS Chemical Biology
DOI: 10.1021/acschembio.0c00285




antibody

[ASAP] A Systematic Evaluation of Antibody Modification and <sup>89</sup>Zr-Radiolabeling for Optimized Immuno-PET

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00087




antibody

[ASAP] Site-Specific Antibody Conjugation Strategy to Functionalize Virus-Based Nanoparticles

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00118




antibody

[ASAP] Expanding the Scope of Antibody Rebridging with New Pyridazinedione–TCO Constructs

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00155




antibody

PRESCIENT: platform for the rapid evaluation of antibody success using integrated microfluidics enabled technology

Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper
Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

Antibody-based eye drop may treat dry eye disease: Study

Dry eye disease is caused by abnormalities in the tear fluid and results in dry areas over the cornea, the transparent outer layer of the eye, which can lead to disabling eye pain and sensitivity to light in severe cases




antibody

Antibody kits arrive from China, but only for surveillance

These kits, also known as serological testing kits, are not meant for early diagnosis or detection of the disease, said Raman Gangakhedkar, head of the department of epidemiology at the Indian Council of Medical Research.




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Avoid use of antibody tests for now: ICMR

The Indian Council of Medical Research on Tuesday advised states not to use the new rapid antibody test for Covid-19 from China till further notice after reports emerged that the kits are faulty. “The kits will be tested and validated in the field by our teams.




antibody

ICMR to give verdict on antibody kits next week

The Indian Council of Medical Research has started analysing results from the evaluation of antibody test kits imported from China and will come out with its conclusions on their efficacy early next week, a senior government official told ET.




antibody

Bio-assay of non-amidated progastrin-derived peptide (G17-Gly) using Tailor-made recombinant antibody fragment and phages display method: A biomedical analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00627K, Paper
Deniz Sadighbayan, Mohammad Reza Tohid-kia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
In this research, four novel and sensitive immunosensor for electrochemical determination of G17-Gly were designed based on signal amplification and tailor-made recombinant antibody technology. Anti-G17-Glyantibody fragments (i.e. scFv and VL...
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

The application of antibody – aptamer hybrid biosensors in the clinical diagnostics and environmental analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00678E, Critical Review
Marta Jarczewska, Elzbieta Malinowska
The growing number of various diseases and the increase of environmental contamination are the causes for elaboration of novel methods for their detection. The possibility of application of affinity-based biosensors...
The content of this RSS Feed (c) The Royal Society of Chemistry




antibody

[ASAP] Characterizing and Quantitating Therapeutic Tethered Multimeric Antibody Degradation Using Affinity Capture Mass Spectrometry

Analytical Chemistry
DOI: 10.1021/acs.analchem.9b05739




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How a SARS patient's antibody binds to the COVID-19 virus

Structural data on the complex could guide drug and vaccine design




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Amgen and Adaptive pursue COVID-19 antibody therapy




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A new generation of antibody-drug conjugates for cancer patients

Advances in chemistry have led to a comeback for ADCs, with more on the way




antibody

IL-6 antibody from Regeneron and Sanofi shows no COVID-19 benefit




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US FDA adjusts course on validating COVID-19 antibody tests




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Mechanisms of [beta]-amyloid clearance by anti-a[beta] antibody therapy




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Optimization of anti-Abeta antibody therapy




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Antibody targeting of non ionic surfactant vesicles to vascular inflammation




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A novel antibody based capture matrix utilizing human serum albumin and streptococcal Protein G to increase capture efficiency of bacteria




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‘Undertake rapid antibody test with available reliable kits of Indian firm’




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Israel minister claims ‘breakthrough’ in developing antibody against coronavirus




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Rapid antibody test helps Chhattisgarh find Patient Zero in hotspot