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Stiff person syndrome (SPS) is a rare neurologic disorder characterized by progressively worsening rigidity and spasms of the axial and limb muscles. Dyspnea has been recently recognized as a common symptom in SPS,¹ and life-threatening respiratory crises have been occasionally reported and suspected to be responsible for sudden death in these patients.^2,3 The pathophysiologic mechanisms of these respiratory manifestations remain unclear. Some authors have hypothesized that rigidity and/or spasm of the muscles of the trunk could prevent normal rib cage movements and excursion of the diaphragm.¹

Alison Roman’s latest comments about Marie Kondo have not sparked joy.

In an interview with The New Consumer about her increased popularity and the avenues she might pursue to capitalize on it, the popular food columnist discussed her hesitance to put her name on a product line—citing the Japanese organization maven and Chrissy Teigen as examples of what she did not foresee in her own future.

“I have a collaboration coming out with [the cookware startup] Material, a capsule collection,” Roman said. “It’s limited edition, a few tools that I designed that are based on tools that I use that aren’t in production anywhere—vintage spoons and very specific things that are one-offs that I found at antique markets that they have made for me.”

Read more at The Daily Beast.

“I didn’t ‘sell out’ by making my dreams come true.”

Chris goes to therapy for his primal EX woes. Anna Marie gets a new mobile addiction. Kelley asserts that Zestiria is NOT the seasoning of...

PAX is history but Chris is still feeling the siren’s call of some of its best games. Alice is busy fending off aliens and hedgehogs....

Wagner Moura and Ana de Armas give strong performances in a mostly effective retelling of the life and tragic death of a celebrated Brazilian diplomat

There’s an old school charm to Sergio, documentarian Greg Barker’s narrative portrait of UN diplomat Sérgio Vieira de Mello, a dramatic retelling of a life he already brought to the screen in a 2009 documentary of the same name. Barker’s knowledge of Sérgio’s life and accomplishments is backgrounded by a clear respect for who he was and so while the film is factually detailed, as one would expect, it’s also rooted in a desire to showcase his humanity, both in and out of work, with Barker deciding to lean into full-tilt romantic tragedy, perhaps also as a way of differentiating his two Sergios.

Related: Love Wedding Repeat review – laboured Netflix romcom farce

This heartwarming documentary traces the lives of a baseball star and her partner, now in their 90s, who pretended to be ‘just good friends’ for decades

This documentary from Netflix is a real heart-soother. Directed with tremendous sensitivity and intimacy by Chris Bolan, it’s a love story about two women now in their 90s – Terry Donahue and Pat Henschel, who have been together since the 1940s.

For decades they kept up the pretence of being “just good friends” to their families before finally coming out a few years ago. Talking to outsiders, they still describe each other as “cousins”. The legacy of shame and fear among older people in the gay community is explored in the film, but the overwhelming mood here is love.

Jameela Jamil also came to Teigen and Kondo's defense, calling Roman "distasteful" and "cliche" for criticizing women of color for being successful in business.

U.S. Vice President Mike Pence's press secretary, the wife of one of President Donald Trump's senior advisers, has tested positive for the coronavirus, raising alarm about the virus' potential spread within the White House's inner most circle.

A woman from Burlington, Ont., says she's had COVID-19 symptoms for nearly two months and hasn't felt entirely supported by health-care workers.

Police are searching for a man they wish to speak to following the attempted rape of a woman in north-east London street.

Read our live coronavirus updates HERE Coronavirus: The symptoms

Follow our live coronavirus updates HERE Coronavirus: the symptoms

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Follow our LIVE updates about the coronavirus outbreak here Coronavirus: The symptoms

Follow our live coronavirus updates HERE Coronavirus: The symptoms

Coronavirus: the symptoms Read our LIVE updates on coronavirus here

Read our live updates on coronavirus HERE Coronavirus: The symptoms

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A US woman has died after contracting coronavirus more than a century after her sister was killed by the 1918 Spanish flu pandemic, according to local obituaries.

At least 16 people have been killed in the deadliest mass shooting in Canada's history.

As the coronavirus pandemic continues worldwide, one woman in New York has devised a simple system to ease the financial burden for those risking their lives on the frontline.

Donations flood in for Margaret Payne's NHS money-raiser as she attempts to mimick a summit of Suilven by making 282 trips upstairs

Northumbria Police warn such behaviour will be treated 'incredibly seriously' after Charlene Merrifield sent to prison for four months

An Essex man has appeared in court accused of fatally running over a woman after a row about a minor collision.

A man who claimed to have coronavirus and spat at police while being arrested for domestic assault has been jailed.

A woman allegedly spat at and threw the contents of a sick bowl over a nurse while being treated for Covid-19 symptoms.

A former NHS nurse who returned to the frontlines to help fight the coronavirus pandemic has shared the moment she held an elderly woman's hand during her last breaths so she didn't die alone from the virus.

The footage of Chanel's "mam" Sandra has been viewed nearly 600,000 times

A woman in her 80s is fighting for her life after she was hit by a van in front of shocked onlookers on a major south London road.

A doctor who became one of the first people in Europe to receive a potential coronavirus vaccine says she is "doing fine" after rumours claimed she had died.

A woman in her 40s was allegedly gang-raped after police quarantined her in a school overnight in India.

The lawyer for the woman who has been charged over the death of teenage motorcyclist Harry Dunn has opened up a dialogue with the UK Foreign Office (FCO), a source has said.

This is the horrifying moment a man struck a pensioner on the head with a metal pipe before stealing the food she'd just bought.

A woman has jailed after she stole a doctor's identity card while he was in a pharmacy.

A man has been jailed for more than two years after dragging a woman along a road with his car before knocking over her boyfriend.