management Center for Global Partnership Helps Fund New EWC Journalism Seminar on Disaster Management & Resiliency By feedproxy.google.com Published On :: Tue, 06 Mar 2012 02:52:10 +0000 Journalists from Pacific Plate countries invited to apply by March 12 HONOLULU (March 5, 2012) – The Japan Foundation’s Center for Global Partnership has awarded the East-West Center close to $100,000 to conduct a journalism seminar focusing on disaster management and resiliency. Journalists from Japan, the U.S., China and other countries bordering the seismically active Pacific tectonic plate are invited to apply by the March 12 deadline. Click here for more information. Full Article
management Practical Considerations For Land Owners And Developers Arising From The Flood And Water Management Act 2010 By www.eversheds.com Published On :: 2011-07-29 The New Act The Flood and Water Management Act 2010 received Royal Assent on 8 April 2010. The Act takes forward several Government strategy documents and, importantly, reflects the Government’s response to Sir Michael Pitt’s Revie... Full Article
management What happens on an assessment of costs when a costs management order has been made By www.eversheds.com Published On :: 2020-04-02 With a few exceptions, costs budgeting applies to the majority of part 7 multi-track matters. Once the costs budget is agreed between the parties, approved by the court or a costs management order has been made, what is the position upon an assessme... Full Article
management Site waste management plans By www.eversheds.com Published On :: 2008-03-05 Site waste management plans will be necessary for construction and demolition work with effect from 6 April 2008. The Site Waste Management Plans Regulations 2008 require site waste management plans for all construction and engineering projects in ... Full Article
management The Court of Justice in Eenheid holds that the day to day management of Property Funds is subject to VAT By www.eversheds.com Published On :: 2015-12-10 The Court of Justice of the European Union delivered its judgment in Case C-595/13 Staatssecretaris van Financiën v Fiscale Eenheid X NV cs on 9 December 2015. Full Article
management Eversheds Sutherland announces new senior management changes in Germany By www.eversheds.com Published On :: 2020-04-30 Eversheds Sutherland has announced two changes to its senior management team in Germany. The global law firm has appointed Dr. Alexander Niethammer as new Managing Partner of its German office, while Hamburg-based Partner, Dr. Carola Rathke, takes u... Full Article
management Nomura Holdings' (NMR) Management on Q4 2020 Results - Earnings Call Transcript By seekingalpha.com Published On :: Sat, 09 May 2020 00:05:11 -0400 Full Article NMR NRSCF SA Transcripts
management Nigerian Red Cross urges Govts to establish ministries of humanitarian affairs, disaster management By nigerianpilot.com Published On :: Sat, 09 May 2020 08:53:56 +0000 — declares Air Peace Boss,Onyema, ‘Hero Of COVID-19’ Considering the global ravages of Corona virus, Nigerian Red Cross said there is urgent need for state governments to establish ministries of humanitarian affairs, disaster management and social development. This, according to the Society, would encourage rapid response to all disaster management activities and alleviate the hardship […] The post Nigerian Red Cross urges Govts to establish ministries of humanitarian affairs, disaster management appeared first on Nigerian Pilot News. Full Article News Featured Nigerian Red Cross
management Diamondback Energy: Quality Guidance From Management By seekingalpha.com Published On :: Fri, 08 May 2020 16:29:12 -0400 Full Article FANG Daniel Jones
management Enterprise Management Incentives By www.eversheds.com Published On :: 2008-03-13 Good and bad news Yesterday, Chancellor Alistair Darling announced some changes to the Enterprise Management Incentive (EMI) legislation, which will impact on those companies operating EMI and those proposing to do so. The good news Under the cu... Full Article
management EBA Guidelines on ICT and Security Risk Management Impact on Outsourcing Arrangements By www.eversheds.com Published On :: 2020-01-28 Overview On 28 November 2019, the European Banking Authority (“EBA”) published its final guidelines[1] on information and communication technology (“ICT”) and security risk management (EBA/GL/2019/04) (the “Guidelines&r... Full Article
management Eversheds Sutherland have advised the management team shareholders on the sale of a minority stake in Waterlogic By www.eversheds.com Published On :: 2020-05-07 Eversheds Sutherland have advised the management team shareholders on the sale of a significant minority stake in Waterlogic, a UK-based designer, manufacturer, distributor and service provider of purified water dispensers, to four strong instituti... Full Article
management Bank Negara Malaysia - Policy Guidance on Risk Management in Technology (RMiT) By www.eversheds.com Published On :: 2019-10-10 The Central Bank of Malaysia or Bank Negara Malaysia (‘BNM’) on 18 July 2019 issued another policy document which sets out its requirements to the nation’s Financial Institutions (‘FIs’) management of technology risk. W... Full Article
management Nomura Holdings' (NMR) Management on Q4 2020 Results - Earnings Call Transcript By seekingalpha.com Published On :: Sat, 09 May 2020 00:05:11 -0400 Full Article NMR NRSCF SA Transcripts
management Triple-S Management Corporation (GTS) CEO Bobby Garcia on Q1 2020 Results - Earnings Call Transcript By seekingalpha.com Published On :: Sat, 09 May 2020 04:23:08 -0400 Full Article GTS SA Transcripts
management Poor management of COVID-19 crisis could lead to more protests in Iran By www.jpost.com Published On :: Wed, 06 May 2020 19:10:23 GMT 'Many mistakes showed that this regime is nothing but a propaganda machine and oppression machine.' Full Article Iran riot
management Punjab opp benches question spending of Rs 11 bn for Covid-19 management By feedproxy.google.com Published On :: Sat, 09 May 2020 06:00:00 +0500 LAHORE: Opposition MPAs Khwaja Salman Rafique and Uzma Bokhari at the Punjab Assembly criticised the Punjab government that it had claimed to have spent Rs 11 billion for tackling corona but the... [[ This is a content summary only. Visit my website for full links, other content, and more! ]] Full Article
management In the Pacific, COVID-19 is changing the way we think about waste management -- by Anupma Jain By blogs.adb.org Published On :: Wed, 22 Apr 2020 11:50:41 +0800 The pandemic is producing more household waste and increased amounts of dangerous medical waste. We need to manage these changes for our immediate safety and for the long-term welfare of our communities. Full Article
management Microchip Smart Storage Adapters Now Interoperate Seamlessly with MegaRAC® SP-X Management Firmware from AMI for At-Scale Secure Storage Management By www.microchip.com Published On :: 11/13/2019 2:04:00 PM Microchip Smart Storage Adapters Now Interoperate Seamlessly with MegaRAC® SP-X Management Firmware from AMI for At-Scale Secure Storage Management Full Article
management Senior IT Officer (Project Management) (3 Vacancies) By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Senior IT Officer (Project Management) (3 Vacancies) in the Information Technology Department . The deadline for submitting applications is on 22 May 2020. Full Article Job Vacancy
management Associate Facilities Planning and Management Officer (Project Management) By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Associate Facilities Planning and Management Officer (Project Management) in the Office of Administrative Services. The deadline for submitting applications is on 22 May 2020. Full Article Job Vacancy
management Budget and Management Services Analyst By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Budget and Management Services Analyst in the Budget, Personnel, and Management Systems Department. The deadline for submitting applications is on 22 May 2020. Full Article Job Vacancy
management Indonesia: Integrated Citarum Water Resources Management Investment Program By feedproxy.google.com Published On :: 2019-12-27 00:00:00 The government of Indonesia wanted to improve land and water management in the Citarum River Basin, and requested assistance from the Asian Development Bank (ADB) to develop a long-term integrated water resources management (IWRM) investment program as part of its strategic road map. In December 2008, ADB approved a multitranche financing facility (MFF) for the Integrated Citarum Water Resources Management Investment Program to support the implementation of the IWRM road map in the basin. A periodic financing request was formulated to implement priority activities from the road map. Full Article Evaluation Document
management People’s Republic of China: Integrated Ecosystem and Water Resources Management in the Baiyangdian Basin Project By feedproxy.google.com Published On :: 2020-05-05 00:00:00 The project’s key objective was to demonstrate an innovative integrated ecosystem and water resources management that will improve the environmental conditions in the Baiyangdian Basin in Hebei province, southwest of Beijing. It focused on the need to conserve Baiyangdian Lake—one of the most important and vulnerable ecosystems in the People’s Republic of China (PRC). It would also contribute to achieving the goals of the Baoding municipality’s Eleventh Five-Year Environmental Protection Plan. Full Article Evaluation Document
management Public Management Officer (Governance) By feedproxy.google.com Published On :: 2020-05-04 00:00:00 ADB has a vacancy for the position of Public Management Officer (Governance) in the Sustainable Development and Climate Change Department. The deadline for submitting applications is on 18 May 2020. Full Article
management Senior IT Officer (Project Management) (3 Vacancies) By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Senior IT Officer (Project Management) (3 Vacancies) in the Information Technology Department . The deadline for submitting applications is on 22 May 2020. Full Article
management Associate Facilities Planning and Management Officer (Project Management) By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Associate Facilities Planning and Management Officer (Project Management) in the Office of Administrative Services. The deadline for submitting applications is on 22 May 2020. Full Article
management Budget and Management Services Analyst By feedproxy.google.com Published On :: 2020-05-08 00:00:00 ADB has a vacancy for the position of Budget and Management Services Analyst in the Budget, Personnel, and Management Systems Department. The deadline for submitting applications is on 22 May 2020. Full Article
management Institutional and Governance Dimensions of Flood Risk Management: A Flood Footprint and Accountability Mechanism By feedproxy.google.com Published On :: 2019-12-20 00:00:00 This working paper proposes flood footprint and accountability to coordinate risk management projects through appropriate spatial planning at river basin scale. Full Article Publication
management ADB's $8.32 Million Financing to Help Prepare Water Resources Management Projects in Punjab By feedproxy.google.com Published On :: 2020-04-15 00:00:00 ADB signed an agreement today to provide $8.32 million in financing to the Government of Pakistan to enable vital preparatory work ahead of a series of major projects to enhance water availability and increase agricultural... Full Article News Release
management Brahma Management to invest Rs 3,000 crore in Indian real estate sector By www.indianrealtynews.com Published On :: Thu, 19 Jun 2014 00:05:20 +0000 Nine years after it was formed, New York-based Brahma Management has lined up big investments for the Indian real estate market . Brahma, an FDI-funded investment and asset management company, has already invested around Rs 2,500 crore in the sector and has plans to put in another Rs 3,000 crore over the next two years. So far, its investments in the realty sector include Gurgaon-based projects Brahma City and Athena, and The Valley, a joint venture township project in Panchkula. While Athena is a retail and commercial office center, Brahma City is a gated township spread over 150 acres of land. Indian real estate market has been facing strong headwinds […] Full Article FDI NRI Real Estate India
management Sustainable Solid-Waste Management Project By www.adb.org Published On :: 2020-04-17 00:00:00 Approved project 51034-002 in Uzbekistan. Full Article
management L2573-PRC: Guiyang Integrated Water Resources Management (Sector) Project [I-A.2-Goods-2] By feedproxy.google.com Published On :: Full Article
management Loan No. 3148-IND: Karnataka Integrated Urban Water Management Investment Program - Tranche 1 [01WS05] By feedproxy.google.com Published On :: Full Article
management Loan No. 3000-NEP: Kathmandu Valley Wastewater Management Project [KUKL-WW/IS-03] By feedproxy.google.com Published On :: Full Article
management HARMAN Announces Executive Management Changes Dinesh Paliwal to step down as President and CEO; Michael Mauser to succeed Paliwal effective April 1, 2020 By news.harman.com Published On :: Mon, 03 Feb 2020 15:06:00 GMT Stamford, CT, Feb. 3, 2020 -- HARMAN, a wholly-owned subsidiary of Samsung Electronics Co., Ltd., focused on connected technologies and solutions for automotive, consumer and enterprise markets, today announced that Dinesh Paliwal will step down on April... Full Article
management Noncardiac Chest Pain May Warrant More Management: Study By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Noncardiac Chest Pain May Warrant More Management: StudyCategory: Health NewsCreated: 4/24/2010 12:10:00 PMLast Editorial Review: 4/26/2010 12:00:00 AM Full Article
management Better Diabetes Blood Sugar Management Leads to Fewer Eye Surgeries By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Better Diabetes Blood Sugar Management Leads to Fewer Eye SurgeriesCategory: Health NewsCreated: 4/29/2015 12:00:00 AMLast Editorial Review: 4/30/2015 12:00:00 AM Full Article
management More Guidance on Inpatient Management of Blood Glucose in COVID-19 By www.webmd.com Published On :: Wed, 06 May 2020 12:05:04 EST Two new graphics from Diabetes UK's COVID-19 task force address inpatient use of subcutaneous insulin for managing hyperglycemia and ketoacidosis when intravenous equipment is unavailable. Full Article
management Severe Pulmonary Hypertension Management Across Europe (PHAROS): an ERS Clinical Research Collaboration By erj.ersjournals.com Published On :: 2020-05-07T01:15:55-07:00 The past 20 years have seen major advances in the understanding and treatment of pulmonary arterial hypertension (PAH; group 1 of the pulmonary hypertension (PH) clinical classification) [1]. A strong basis of knowledge has been acquired in: 1) large randomised clinical trials for drug development; 2) national registries for epidemiology and outcome; and 3) smaller studies on the pathophysiological mechanisms of the disease. This knowledge has been reviewed at World Symposia on Pulmonary Hypertension (the most recent in 2018 [2]) and summarised in European Respiratory Society (ERS)/European Society of Cardiology (ESC) clinical guidelines (the most recent in 2015 [3, 4]). We are, however, much less knowledgeable on specific aspects such as 1) the implementation of guidelines and access to therapies in different European countries; 2) the management of PH crises and progressive (acute on chronic) heart failure; and 3) other groups of PH, such as PH due to lung diseases. Therapeutic strategies also need to be optimised, in particular regarding the combination of drugs, the use of anticoagulants, the place for new medications targeting different pathophysiological pathways, etc. Full Article
management Racial and Ethnic Differences in Emergency Department Pain Management of Children With Fractures By pediatrics.aappublications.org Published On :: 2020-05-01T01:00:46-07:00 OBJECTIVES: To test the hypotheses that minority children with long-bone fractures are less likely to (1) receive analgesics, (2) receive opioid analgesics, and (3) achieve pain reduction. METHODS: We performed a 3-year retrospective cross-sectional study of children <18 years old with long-bone fractures using the Pediatric Emergency Care Applied Research Network Registry (7 emergency departments). We performed bivariable and multivariable logistic regression to measure the association between patient race and ethnicity and (1) any analgesic, (2) opioid analgesic, (3) ≥2-point pain score reduction, and (4) optimal pain reduction (ie, to mild or no pain). RESULTS: In 21 069 visits with moderate-to-severe pain, 86.1% received an analgesic and 45.4% received opioids. Of 8533 patients with reassessment of pain, 89.2% experienced ≥2-point reduction in pain score and 62.2% experienced optimal pain reduction. In multivariable analyses, minority children, compared with non-Hispanic (NH) white children, were more likely to receive any analgesics (NH African American: adjusted odds ratio [aOR] 1.72 [95% confidence interval 1.51–1.95]; Hispanic: 1.32 [1.16–1.51]) and achieve ≥2-point reduction in pain (NH African American: 1.42 [1.14–1.76]; Hispanic: 1.38 [1.04–1.83]) but were less likely to receive opioids (NH African American: aOR 0.86 [0.77–0.95]; Hispanic: aOR 0.86 [0.76–0.96]) or achieve optimal pain reduction (NH African American: aOR 0.78 [0.67–0.90]; Hispanic: aOR 0.80 [0.67–0.95]). CONCLUSIONS: There are differences in process and outcome measures by race and ethnicity in the emergency department management of pain among children with long-bone fractures. Although minority children are more likely to receive analgesics and achieve ≥2-point reduction in pain, they are less likely to receive opioids and achieve optimal pain reduction. Full Article
management Cervical Spondylotic Myelopathy: A Guide to Diagnosis and Management By www.jabfm.org Published On :: 2020-03-16T09:31:37-07:00 Cervical spondylotic myelopathy (CSM) is a neurologic condition that develops insidiously over time as degenerative changes of the spine result in compression of the cord and nearby structures. It is the most common form of spinal cord injury in adults; yet, its diagnosis is often delayed. The purpose of this article is to review the pathophysiology, natural history, diagnosis, and management of CSM with a focus on the recommended timeline for physicians suspecting CSM to refer patients to a spine surgeon. Various processes underlie spondylotic changes of the canal and are separated into static and dynamic factors. Not all patients with evidence of cord compression will present with symptoms, and the progression of disease varies by patient. The hallmark symptoms of CSM include decreased hand dexterity and gait instability as well as sensory and motor dysfunction. magnetic resonance imaging is the imaging modality of choice in patients with suspected CSM, but computed tomography myelography may be used in patients with contraindications. Patients with mild CSM may be treated surgically or nonoperatively, whereas those with moderate-severe disease are treated operatively. Due to the long-term disability that may result from a delay in diagnosis and management, prompt referral to a spine surgeon is recommended for any patient suspected of having CSM. This review provides information and guidelines for practitioners to develop an actionable awareness of CSM. Full Article
management Pathogenesis and Management of Indirect Hyperbilirubinemia in Preterm Neonates Less Than 35 Weeks: Moving Toward a Standardized Approach By neoreviews.aappublications.org Published On :: 2020-05-01T01:00:20-07:00 Premature infants have a higher incidence of indirect hyperbilirubinemia than term infants. Management of neonatal indirect hyperbilirubinemia in late preterm and term neonates has been well addressed by recognized, consensus-based guidelines. However, the extension of these guidelines to the preterm population has been an area of uncertainty because of limited evidence. This leads to variation in clinical practice and lack of recognition of the spectrum of bilirubin-induced neurologic dysfunction (BIND) in this population. Preterm infants are metabolically immature and at higher risk for BIND at lower bilirubin levels than their term counterparts. Early use of phototherapy to eliminate BIND and minimize the need for exchange transfusion is the goal of treatment in premature neonates. Although considered relatively safe, phototherapy does have side effects, and some NICUs tend to overuse phototherapy. In this review, we describe the epidemiology and pathophysiology of BIND in preterm neonates, and discuss our approach to standardized management of indirect hyperbilirubinemia in the vulnerable preterm population. The proposed treatment charts suggest early use of phototherapy in preterm neonates with the aim of reducing exposure to high irradiance levels, minimizing the need for exchange transfusions, and preventing BIND. The charts are pragmatic and have additional curves for stopping phototherapy and escalating its intensity. Having a standardized approach would support future research and quality improvement initiatives that examine dose and duration of phototherapy exposure with relation to outcomes. Full Article
management Neonatal Management During the Coronavirus Disease (COVID-19) Outbreak: The Chinese Experience By neoreviews.aappublications.org Published On :: 2020-05-01T01:00:20-07:00 Full Article
management Geospatial assessment methods for geotechnical asset management of legacy railway embankments By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 Most British railway embankments were constructed between 120 and 180 years ago without the benefit of modern design and construction methods. This can result in undesirable load-deformation characteristics and consequent disruption to present-day railway operations, for which there is unprecedented demand. Annual rail passenger kilometres have approximately doubled in the last 20 years and freight has increased by 60% over the same period. Whereas elements such as rails or bridges can be refurbished or replaced to meet increasing demand, the same is not usually feasible for embankments. Development of techniques to assess embankment performance risks posed by operational capacity enhancements is therefore of increasing significance to railway geotechnical asset management. The two case studies presented in this paper demonstrate how geospatial analysis and data management techniques may be applied to this challenge at both strategic (regional or national) and tactical (site-specific) scales for embankments incorporating plastic clay fill. The case studies also demonstrate, in a world of ever more abundant data, the growing need for engineering geologists and geotechnical engineers to augment their traditional knowledge with comprehensive data management and geospatial analysis skills, these being essential for modern infrastructure asset management. Thematic collection: This article is part of the ‘Ground-related risk to transportation infrastructure’ collection available at: https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure Full Article
management Strategic geotechnical asset management By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 Strategic geotechnical asset management considers the whole of an organization's earthworks portfolio and is concerned with setting an overall earthworks asset management policy with long-term objectives related to asset performance, safety and condition, and identifying how those objectives can best be met, now and into the future. A risk-based approach is adopted that requires an understanding of the likelihood that any of the earthworks may fail, combined with a knowledge of the consequences should they fail. Procedures are required to identify those earthworks that are most vulnerable to failure under the influence of triggering events, such as extreme weather. The risks are managed through a mix of interventions to reduce the likelihood of failure and mitigations to reduce the impact of failure. Many of the challenges of implementing a strategic earthworks policy have, or are, being met by the main UK transportation infrastructure organizations. Thematic collection: This article is part of the Ground-related risk to transportation infrastructure collection available at https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure Full Article
management Decision tree as a tool for the management of coastal aquifers of limited saturated thickness By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 In this paper, a decision tree is presented, constructed on the basis of hydrogeological characteristics (water table depth, freshwater thickness, surface area required and distance between wells), to choose the optimal groundwater extraction method in the case of a coastal unconfined aquifer. A comparison is made of the groundwater extraction methods in a freshwater aquifer of limited thickness occurring in coastal dunes in the eastern region of the Province of Buenos Aires (Argentina). The negative effects brought about by the wrong use of the groundwater extraction methods are analysed, because, as a result of excessive extraction, such methods lead to the dramatic decrease of the freshwater reserves. The decision tree is a useful tool to assist decision-makers as it suggests the most suitable groundwater extraction method options (vertical wells or wellpoints), as well as identifying areas that are unsuitable for sustainable groundwater extraction. Full Article
management Pharmacy-Based Infectious Disease Management Programs Incorporating CLIA-Waived Point-of-Care Tests [Minireviews] By jcm.asm.org Published On :: 2020-04-23T08:00:28-07:00 There are roughly 48,000 deaths caused by influenza annually and an estimated 200,000 people who have undiagnosed human immunodeficiency virus (HIV). These are examples of acute and chronic illnesses that can be identified by employing a CLIA-waived test. Pharmacies across the country have been incorporating CLIA-waived point-of-care tests (POCT) into disease screening and management programs offered in the pharmacy. The rationale behind these programs is discussed. Additionally, a summary of clinical data for some of these programs in the infectious disease arena is provided. Finally, we discuss the future potential for CLIA-waived POCT-based programs in community pharmacies. Full Article
management Management of acute COPD exacerbations in Australia: do we follow the guidelines? By openres.ersjournals.com Published On :: 2020-04-19T07:30:12-07:00 Objective We aimed to assess adherence to the Australian national guideline (COPD-X) against audited practice, and to document the outcomes of patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease (COPD) at discharge and 28 days after. Methods A prospective clinical audit of COPD hospital admission from five tertiary care hospitals in five states of Australia was conducted. Post-discharge follow-up was conducted via telephone to assess for readmission and health status. Results There were 207 admissions for acute exacerbation (171 patients; mean 70.2 years old; 50.3% males). Readmission rates at 28 days were 25.4%, with one (0.6%) death during admission and eight (6.1%) post-discharge within 28 days. Concordance to the COPD-X guidance was variable; 22.7% performed spirometry, 81.1% had blood gases collected when forced expiratory volume in 1 s was <1 L, 99.5% had chest radiography performed, 95.1% were prescribed systemic corticosteroids and 95% were prescribed antibiotic therapy. There were 89.1% given oxygen therapy and 92.6% when arterial oxygen tension was <80 mmHg; 65.6% were given ventilatory assistance when pH was <7.35. Only 32.4% were referred to pulmonary rehabilitation but 76.8% had general practitioner follow-up arranged. Conclusion When compared against clinical practice guidelines, we found important gaps in management of patients admitted with COPD throughout tertiary care centres in Australia. Strategies to improve guideline uptake are needed to optimise care. Full Article
management Survival benefit of lung transplantation compared with medical management and pulmonary rehabilitation for patients with end-stage COPD By openres.ersjournals.com Published On :: 2020-04-27T00:30:10-07:00 Background COPD patients account for a large proportion of lung transplants; lung transplantation survival benefit for COPD patients is not well established. Methods We identified 4521 COPD patients in the United Network for Organ Sharing (UNOS) dataset transplanted from May 2005 to August 2016, and 604 patients assigned to receive pulmonary rehabilitation and medical management in the National Emphysema Treatment Trial (NETT). After trimming the populations for NETT eligibility criteria and data completeness, 1337 UNOS and 596 NETT patients remained. Kaplan–Meier estimates of transplant-free survival from transplantation for UNOS, and NETT randomisation, were compared between propensity score-matched UNOS (n=401) and NETT (n=262) patients. Results In propensity-matched analyses, transplanted patients had better survival compared to medically managed patients in NETT (p=0.003). Stratifying on 6 min walk distance (6 MWD) and FEV1, UNOS patients with 6 MWD <1000 ft (~300 m) or FEV1 <20% of predicted had better survival than NETT counterparts (median survival 5.0 years UNOS versus 3.4 years NETT; log-rank p<0.0001), while UNOS patients with 6 MWD ≥1000 ft (~300 m) and FEV1 ≥20% had similar survival to NETT counterparts (median survival, 5.4 years UNOS versus 4.9 years NETT; log-rank p=0.73), interaction p=0.01. Conclusions Overall survival is better for matched lung transplant patients compared with medical management alone. Patients who derive maximum benefit are those with 6 MWD <1000 ft (~300 m) or FEV1 <20% of predicted, compared with pulmonary rehabilitation and medical management. Full Article