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Principal Investigator/Professor Positions at Max-Planck Center for Tissue Stem Cell Research and Regenerative Medicine, GDL

With a generous support from the Guangzhou City Government and the Guangdong Provincial Government, Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL) was launched in 2017. GRMH-GDL aims to bring together multiple leading scientific research units from Guangdong, Hong Kong, Macao and well-known international research institutes to achieve the vital goal of "Healthy China" and to cooperatively tackle the scientific and technical problems and challenges. GRMH-GDL is focused…




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Early assessment of <i>KRAS</i> mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer




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Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank




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Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma




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The untapped potential of ascites in ovarian cancer research and treatment




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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British Journal of Cancer




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Surrogate endpoints for overall survival for patients with metastatic hormone-sensitive prostate cancer in the CHAARTED trial




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The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer




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African-American men with low-risk prostate cancer treated with radical prostatectomy in an equal-access health care system: implications for active surveillance




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Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer




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Telomere-based risk models for the early diagnosis of clinically significant prostate cancer




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Exposure to direct-to-consumer advertising is associated with overestimation of benefits regarding ultrahypofractionated radiation therapy for prostate cancer




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PARP inhibitors as a new therapeutic option in metastatic prostate cancer: a systematic review




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Prostate Cancer and Prostatic Diseases




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Author Correction: Guidance for quantitative confocal microscopy




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




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MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer

Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers.




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Translational balance

Moving discoveries from academia to industry requires a delicate balance of risk, reward, skill sets and personalities, according to a translational panel held at BIO-Europe's partnering conference.




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials




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UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53




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Cancer Gene Therapy




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Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy




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Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy




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Ex vivo pulsed dendritic cell vaccination against cancer




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Microbiota and colorectal cancer: colibactin makes its mark




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Inducing senescence sensitizes pancreatic tumours to therapies




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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A more accurate incidence of acute spinal cord injury in South Korea can be estimated by the national health insurance system




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Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors




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Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea




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Fixed orthodontic appliances: a practical guide




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Impact of the COVID-19 lockdown on basic science research in ophthalmology: the experience of a highly specialized research facility in France




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Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry




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Joseph S. Nye: U.S. and China Need a More Cooperative Security Stance

Joseph S. Nye: U.S. and China Need a More Cooperative Security Stance




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Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership

History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question.




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Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis




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Comments on “The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study”




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A Financial Sanctions Dilemma

Over the last two decades, there has been a dramatic increase in the popularity of financial sanctions as an instrument of US foreign policy to address security threats ranging from weapons of mass destruction (WMD) proliferation and terrorism to human rights violations and transnational crime. Washington’s policymakers have prized these tools for their ability to rapidly apply pressure against foreign targets with few perceived repercussions against American business interests. The problem, however, is that Washington is ignoring a growing tension between financial sanctions designed to support economic statecraft (with non-financial goals) and those designed to protect the international financial system. Confusing the two sends mixed signals to adversaries as well as allies and undermines US credibility and commitment to upholding international banking rules and norms. If Washington cannot reconcile these competing processes, it is unlikely that future administrations will enjoy the same foreign policy levers, leaving the United States at a significant disadvantage.




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After Social Distancing, a Strange Purgatory Awaits

Life right now feels very odd. And it will feel odd for months—and even years—to come.




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Factoring Pandemic Risks into Financial Modelling

Today’s economic crisis leaves us with an unsettling and perplexing regret. Why weren’t financial portfolios already adjusted for risks that stem from health events such as pandemics? After all, financial portfolios are adjusted for liquidity risks, market risks, credit risks, and even operational and political risks.




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After Social Distancing, a Strange Purgatory Awaits

Life right now feels very odd. And it will feel odd for months—and even years—to come.




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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers