take Scientists Maria Banks and Sharon Purdy explain how to take your own photo of Mars. By insider.si.edu Published On :: Tue, 25 Jun 2013 18:17:48 +0000 Smithsonian planetary geologists Sharon Purdy and Maria Banks explain how you can take your very own photo of Mars. The post Scientists Maria Banks and Sharon Purdy explain how to take your own photo of Mars. appeared first on Smithsonian Insider. Full Article Research News Science & Nature Video
take Take a 3D tour of the 1903 Wright Flyer! By insider.si.edu Published On :: Thu, 21 Nov 2013 19:22:05 +0000 Click photo to take a tour of the 1903 Wright Flyer with Smithsonian X 3D Explorer. The Smithsonian X 3D Collection features objects from the […] The post Take a 3D tour of the 1903 Wright Flyer! appeared first on Smithsonian Insider. Full Article History & Culture Science & Nature Video aeronautics materials science National Air and Space Museum science education technology
take Can animals take a selfie? By insider.si.edu Published On :: Wed, 21 May 2014 18:43:44 +0000 Yes! When an animal trips a “camera trap” as a part of a project between the North Carolina Museum of Natural Sciences and the Smithsonian. […] The post Can animals take a selfie? appeared first on Smithsonian Insider. Full Article Science & Nature Video
take 3-D imaging takes Smithsonian from Washington to the world By insider.si.edu Published On :: Tue, 10 Feb 2015 15:43:49 +0000 The Smithsonian has launched an ambitious project to scan millions of items and make them available to the world on a searchable database. CBS reporter […] The post 3-D imaging takes Smithsonian from Washington to the world appeared first on Smithsonian Insider. Full Article Anthropology History & Culture Science & Nature Video collections conservation digitization insects materials science National Museum of Natural History technology
take How To Take As Screenshot From A Running .avi Video (windows Mediaplayer) By www.bleepingcomputer.com Published On :: 2006-02-19T15:21:51-05:00 Full Article
take With 800 color photographs, new book takes a fascinating look inside palms By insider.si.edu Published On :: Wed, 01 Jun 2011 13:17:51 +0000 The chief appeal of The Anatomy of Palms is some 800 color photographs that document the extent of palm anatomical diversity. The post With 800 color photographs, new book takes a fascinating look inside palms appeared first on Smithsonian Insider. Full Article Book Review Plants Research News Science & Nature conservation biology fossils National Museum of Natural History
take Smithsonian scientists discover that rainforests take the heat By insider.si.edu Published On :: Thu, 30 May 2013 17:31:10 +0000 South American rainforests thrived during three extreme global warming events in the past, say paleontologists at the Smithsonian Tropical Research Institute in a new report […] The post Smithsonian scientists discover that rainforests take the heat appeared first on Smithsonian Insider. Full Article Plants Research News Science & Nature biodiversity carbon dioxide climate change conservation biology rain forests South America Tropical Research Institute
take Why does cmdagent.exe (Comodo Firewall) take up so much CPU? By www.bleepingcomputer.com Published On :: 2020-04-30T06:38:38-05:00 Full Article
take Jon Stewart is leaving 'The Daily Show'; who could take his place? By feeds.scpr.org Published On :: Tue, 10 Feb 2015 16:29:18 -0800 Host Jon Stewart of Comedy Central's "The Daily Show with Jon Stewart" watches a video while taping "The Daily Show with Jon Stewart: Restoring Honor & Dignity to the White House" at the McNally Smith College of Music Sept. 5, 2008 in St. Paul, Minnesota.; Credit: Ethan Miller/Getty Images for Comedy Central Mike RoeHost Jon Stewart announced at Tuesday's "The Daily Show" taping that he is leaving the show. Comedy Central confirmed the news in a statement, saying that Stewart will be leaving later this year: "For the better part of the last two decades, we have had the incredible honor and privilege of working with Jon Stewart. His comedic brilliance is second to none. Jon has been at the heart of Comedy Central, championing and nurturing the best talent in the industry, in front of and behind the camera. Through his unique voice and vision, ‘The Daily Show’ has become a cultural touchstone for millions of fans and an unparalleled platform for political comedy that will endure for years to come. Jon will remain at the helm of ‘The Daily Show’ until later this year. He is a comic genius, generous with his time and talent, and will always be a part of the Comedy Central family." The news comes less than two months after Stephen Colbert brought "The Colbert Report" to an end in order to prepare for hosting CBS's "Late Show," replacing David Letterman after he leaves later this year. "The Daily Show" existed before Jon Stewart, hosted from 1996 until 1998 by Craig Kilborn, but Stewart took the show into a bolder political direction and made it a cultural landmark, becoming the go-to news source for numerous young people. Polls started to show Jon Stewart as being one of the most trusted newsmen in America. It's just over three weeks after Comedy Central launched "The Nightly Show" with Larry Wilmore and details have yet to be announced about the future of Comedy Central's late night lineup. The show has created hosts for other networks, with Colbert leaving for CBS after getting his start as a "Daily Show" correspondent and John Oliver, who served as a fill-in host while Stewart shot the film "Rosewater," left for his own weekly rundown of the news "Last Week Tonight" at HBO. The show's starmaking power also includes actors such as Steve Carell, Ed Helms and more, and new "Saturday Night Live" Weekend Update anchor Michael Che. Stewart didn't announce his plans for what comes next. He directed the 2014 film "Rosewater," based on journalist Maziar Bahari's memoir detailing his imprisonment in Iran following an interview with "The Daily Show's" Jason Jones. Stewart previously talked about "Rosewater" with KPCC's "The Frame," saying at the time that "The Daily Show" isn't all fun. "As sad as it sounds, people might say, 'Man, working at 'The Daily Show,' that's gotta be a blast. You just sit around and laugh all day,'" Stewart said. "And you're like, 'No, we have a meeting at 9, and the 9 meeting has to be over by 9:30, and the scripts have to be in by 11, because if they're not, then we miss this deadline.'" He also told the Hollywood Reporter last summer that he didn't know how much longer he would stay with the show. "I mean, like anything else, you do it long enough, you will take it for granted, or there will be aspects of it that are grinding. I can't say that following the news cycle as closely as we do and trying to convert that into something either joyful or important to us doesn't have its fraught moments," Stewart said. The show, one of Comedy Central's top franchises, will likely continue. John Oliver and Stephen Colbert would have seemed like the heirs apparent before they left; of the current staff, Samantha Bee, Jason Jones and Aaasif Mandvi are the longest-running correspondents, with Bee starting all the way back in 2003. Jones filled in for Stewart as anchor last fall, assisted by his wife Samantha Bee, when Stewart was out sick. The show has also pushed for expanded diversity in its own cast, along with launching "The Nightly Show" with a black host and a minority panel, so that could point to a more diverse host in the future. The show has also recently expanded its international perspective, with Trevor Noah covering international news, Hasan Minhaj as the new Indian correspondent and Egyptian satirist Bassem Youssef joining as a Middle East correspondent. Correction: An earlier version of this story referred to "Rosewater" as a documentary; it is a drama, based on Maziar Bahari's memoir. KPCC regrets the error. This story has been updated. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
take Stemline Shares Take Off on $677 Million Buyout Offer by Global Pharmaceutical Firm By www.streetwisereports.com Published On :: Mon, 04 May 2020 00:00:00 PST Source: Streetwise Reports 05/04/2020 Shares of Stemline Therapeutics traded 150% higher after the company reported that it has entered into a definitive agreement to be acquired by Italy's Menarini Group in a deal valued at up to $677 million.Stemline Therapeutics Inc. (STML:NASDAQ), which is focused on developing and commercializing novel oncology therapeutics, today announced that it has entered into a definitive agreement to be acquired by private Italian pharmaceutical and diagnostics company Menarini Group in a transaction valued up to $677 million. The companies advised that the transaction has already been unanimously approved by both companies' Boards of Directors and that the transaction is expected to close in Q2/20 subject to customary closing conditions, regulatory approvals and a tender of at least 50% of the outstanding Stemline shares by shareholders. Menarini stated that it plans to fund the purchase by using existing cash resources. The firms outlined that purchase details and advised that "under the terms of the agreement, a wholly owned subsidiary of the Menarini Group will commence a tender offer for all outstanding shares of Stemline, whereby Stemline shareholders will be offered a total potential consideration of $12.50 per share, consisting of an upfront payment of $11.50 in cash and one non-tradeable Contingent Value Right (CVR) that will entitle each holder to an additional $1.00 in cash per share upon completion of the first sale of ELZONRIS in any EU5 country after European Commission approval." The report explained that ELZONRIS is a novel targeted therapy directed to the interleukin-3 (IL-3) receptor-α (CD123) and was developed by Stemline for treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adult and pediatric patients. The firm stated that the U.S. Food and Drug Administration (FDA) approved that drug in the U.S. in December 2018. A marketing authorization application (MAA) has already been submitted and is presently under review by the European Medicines Agency. Post acquisition, Menarini expects to obtain approvals and expand distribution of ELZONRIS to Europe and emerging markets. Stemline Therapeutics' Chairman, CEO and Founder Ivan Bergstein, M.D., commented, "Joining Menarini represents a unique opportunity for Stemline to advance the commercialization of ELZONRIS across the globe and to accelerate the development of our pipeline of oncology assets. ...We are excited to be combining with a like-minded organization in Menarini, in a transaction that will deliver immediate and significant cash value to our shareholders, while also allowing our shareholders to participate in the future upside of ELZONRIS's European launch." Elcin Barker Ergun, CEO of Menarini Group, remarked, "Stemline is an excellent fit for Menarini, enabling us to expand our presence in the U.S. with an established biopharmaceutical company focused on developing oncology therapeutics. Through this acquisition, we will continue to strengthen our portfolio and pipeline of oncology assets and deliver novel therapies around the world." The company described BPDCN, formerly blastic NK-cell lymphoma, as "an aggressive hematologic malignancy, often with cutaneous manifestations, with historically poor outcomes which typically presents in the bone marrow and/or skin and may also involve lymph nodes and viscera." Stemline Therapeutics is a commercial-stage biopharmaceutical company headquartered in New York that develops and markets oncology therapeutics. The firm stated that its "ELZONRIS® (tagraxofusp) is a targeted therapy directed to CD123 and is FDA-approved and commercially available in the U.S. for the treatment of adult and pediatric patients, two years and older, with BPDCN." Stemline noted that ELZONRIS is also being currently being evaluated in clinical studies for other indications including chronic myelomonocytic leukemia, myelofibrosis and acute myeloid leukemia. The Menarini Group is an international pharmaceutical company based in Italy which operates and sells its products in more than 100 countries. The company stated that it has $4.2 billion in sales annually. The company's medicines address many areas of illnesses including cardiovascular, gastroenterology, metabolic, infectious diseases and anti-inflammatory/analgesic therapeutic areas and oncology. Stemline Therapeutics began the day with a market capitalization of around $249.2 million with approximately 54.27 million shares outstanding and a short interest of about 11.3%. STML shares opened nearly 150% higher today at $11.81 (+$7.06, +148.63%) over Friday's closing price of $4.75. The stock has traded today between $1.81 and $12.35 per share and is currently trading at $12.10 (+$7.35, +154.74%). Sign up for our FREE newsletter at: www.streetwisereports.com/get-news Disclosure: 1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None. 2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees. 3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. 4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports. 5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases. 6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice. ( Companies Mentioned: STML:NASDAQ, ) Full Article
take Tencent acquires 5% stake in Afterpay By feedproxy.google.com Published On :: Tue, 05 May 2020 14:07:00 +0200 Hong-Kong-based mobile commerce conglomerate Tencent has acquired a 5% stake in... Full Article
take Adults Need to Increase Intake of Folate - Some Women Should Take More By feedproxy.google.com Published On :: Tue, 07 Apr 1998 05:00:00 GMT Women who might become pregnant need 400 micrograms of folic acid per day to reduce their risk of having a child with neural tube defects, according to the latest report on Dietary Reference Intakes (DRIs) from the Institute of Medicine. Full Article
take Fruits and Vegetables Yield Less Vitamin A Than Previously Thought - Upper Limit Set for Daily Intake of Vitamin A and Nine Other Nutrients By feedproxy.google.com Published On :: Tue, 09 Jan 2001 06:00:00 GMT Darkly colored, carotene-rich fruits and vegetables -- such as carrots, sweet potatoes, and broccoli -- provide the body with half as much vitamin A as previously thought. Full Article
take Report Sets Dietary Intake Levels for Water, Salt, and Potassium To Maintain Health and Reduce Chronic Disease Risk By feedproxy.google.com Published On :: Wed, 11 Feb 2004 06:00:00 GMT The vast majority of healthy people adequately meet their daily hydration needs by letting thirst be their guide, says the newest report on nutrient recommendations from the Institute of Medicine of the National Academies. Full Article
take Medication Errors Injure 1.5 Million People and Cost Billions of Dollars Annually - Report Offers Comprehensive Strategies for Reducing Drug-Related Mistakes By feedproxy.google.com Published On :: Thu, 20 Jul 2006 05:00:00 GMT Medication errors are among the most common medical errors, harming at least 1.5 million people every year, says a new report from the Institute of Medicine of the National Academies. Full Article
take IOM Report Sets New Dietary Intake Levels for Calcium and Vitamin D To Maintain Health and Avoid Risks Associated With Excess By feedproxy.google.com Published On :: Tue, 30 Nov 2010 06:00:00 GMT Most Americans and Canadians up to age 70 need no more than 600 international units (IUs) of vitamin D per day to maintain health, and those 71 and older may need as much as 800 IUs, says a new report from the Institute of Medicine. Full Article
take Daniel Kahnemans Thinking, Fast and Slow Wins Best Book Award From Academies - Milwaukee Journal Sentinel, Slate Magazine, and WGBH/NOVA Also Take Top Prizes in Awards 10th Year By feedproxy.google.com Published On :: Thu, 13 Sep 2012 05:00:00 GMT Recipients of the 10th annual Communication Awards were announced today by the National Academy of Sciences, National Academy of Engineering, and Institute of Medicine. Full Article
take New Report Recommends Methods and Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease By feedproxy.google.com Published On :: Thu, 03 Aug 2017 05:00:00 GMT A new report from the National Academies of Sciences, Engineering, and Medicine outlines how to examine whether specific levels of nutrients or other food substances (NOFSs) can ameliorate the risk of chronic disease and recommends ways to develop dietary reference intakes (DRI) based on chronic disease outcomes. Full Article
take Academic Biomedical Research Community Should Take Action to Build Resilience to Disasters By feedproxy.google.com Published On :: Thu, 10 Aug 2017 05:00:00 GMT The academic biomedical research community should improve its ability to mitigate and recover from the impacts of disasters, says a new report from the National Academies of Sciences, Engineering, and Medicine. Full Article
take DOE Should Take Steps Toward Facilitating Energy Development on Its Public Lands By feedproxy.google.com Published On :: Thu, 28 Sep 2017 05:00:00 GMT The U.S. Department of Energy should place a higher priority on developing an accurate and actionable inventory of agency-owned or managed properties that can be leased or sold for energy development, says a new report from the National Academies of Sciences, Engineering, and Medicine. Full Article
take Colleges and Universities Should Take Action to Address Surge of Enrollments in Computer Science By feedproxy.google.com Published On :: Thu, 26 Oct 2017 05:00:00 GMT U.S. colleges and universities should respond with urgency to the current surge in undergraduate enrollments in computer science courses and degree programs, which is straining resources at many institutions, says a new report from the National Academies of Sciences, Engineering, and Medicine. Full Article
take Sodium and Potassium Dietary Reference Intake Values Updated in New Report By feedproxy.google.com Published On :: Tue, 05 Mar 2019 06:00:00 GMT A new report from the National Academies of Sciences, Engineering, and Medicine reviews current evidence and updates intake recommendations known as the Dietary Reference Intakes (DRIs) for sodium and potassium that were established in 2005. Full Article
take Dirty for the drought: LA Waterkeeper wants you to take the no-car wash pledge By www.scpr.org Published On :: Fri, 26 Sep 2014 15:14:01 -0700 When it comes to water usage, not all car washes are created equal. Most car washes don’t recycle water, but more and more newly built car washes are starting to. Santa Ana Express Car Wash opened three years ago and its million-dollar equipment recycles 70 percent of its water.; Credit: Maya Sugarman/KPCC Molly PetersonWashing your car with a garden hose can use up to 120 gallons of water. Most corner conveyor belt operations use less, but all that water can add up, as we told you in August. That’s why the group LA Waterkeeper is challenging motorists to drive dirty and pledge to skip car washes for 60 days. "Water conservation is the easiest and most affordable way to quickly reduce water demand and also extend supplies into next year," says Liz Crosson, the group's executive director. This summer Ventura County’s water agency asked people to skip washing their rides for a month; some people got detailing and car washes as a reward. Crosson’s group is hoping bragging rights will be enough of an incentive. (Though there are some as-yet-undisclosed prizes.) People who live in LA are really excited and interested by the cars that they drive," Crosson says. "And frankly, you can have a dirty car and you can have a sticker and have an excuse for having a dirty car so it saves your image too." The campaign’s just kicking off this weekend (at the Abbott-Kinney festival), but Crosson’s already optimistic for success. Early adopters of the pledge are hundreds of people from the online site Reddit and the general manager for the Los Angeles Department of Water and Power. GO DIRTY FOR THE DROUGHT. Take the #DirtyCarPledge to not wash your car for 60 days. Ready, Set, Go Dirty! http://t.co/TsxdvsgpCv — LAWaterkeeper (@LAWaterkeeper) September 25, 2014 From the ED, I’m Molly Peterson, 89-point-3. KPCC. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
take Supreme Court Arguments A Tech Success, But Format Strangles Usual Give-And-Take By feeds.scpr.org Published On :: Mon, 04 May 2020 18:00:13 -0700 It was a new day at the Supreme Court, which for the first time ever live-streamed oral arguments.; Credit: Andrew Harnik/AP Nina Totenberg | NPRThe U.S. Supreme Court made history Monday. The coronavirus lockdown forced the typically cautious court to hear arguments for the first time via telephone, and to stream the arguments live for the public to hear. Chief Justice John Roberts was at the court as the telephone session began, one or two other justices were in their offices at the court, and the rest of the justices dialed in from home. The first and only case heard Monday involved an arcane trademark question only a lawyer could love. Online travel search engine Booking.com is appealing a U.S. Patent and Trademark Office refusal to grant a trademark to the company. With the justices asking questions in order of seniority, the first big surprise was that Justice Clarence Thomas, who in the past has gone years without asking a question, did ask one, several in fact, when it came his turn. "Could Booking acquire an 800 number ... that's a vanity number, 1-800-BOOKING, for example?" Thomas asked Assistant Solicitor General Erica Ross. Yes, replied Ross, but domain names pose a different problem than phone numbers. Ultimately, she argued "the core problem with Booking.com is that it allows [Booking.com] to monopolize booking on the internet" to the exclusion of other sites like hotelbooking.com. Justice Stephen Breyer followed up when his turn came: "Same question as Justice Thomas ... good morning, anyway ... You can have a trademark that's an address. You can have a trademark that's a telephone number. So why can't you have a trademark that's a dot-com?" Justice Samuel Alito noted that the court's prior decision in this area of the law was more than 100 years old, and the statute dealing with trademarks was similarly enacted decades ago. "How can a rule that makes sense in the internet age be reconciled with the language" in these "pre-Internet era" laws? asked Alito. Next up to her lectern from her home was lawyer Lisa Blatt. This was her 40th Supreme Court argument and despite being a veteran, she said later that she was, as usual, sick to her stomach beforehand. But once at the lectern "it's always a rush of excitement," she said, and this time it was a special rush. "I loved getting a question from Justice Thomas ... I would go to the phone for the foreseeable future if I could get Justice Thomas to ask questions. That was wonderful," she said. Indeed, despite the new format Blatt and Ross seemed to have had a good time. "Your client would not object to the registration of any trademark that simply made a slight variation in Booking.com?" asked Alito. "There's a million booking registrations already," parried Blatt. Alito: "Would you just answer the question." Blatt: "They don't and have not and would not." Not, she added, unless another company ripped off the trademark with no variation. That would be theft, she said. So, when when the argument was over, what was her reaction? "After I hung up, I screamed, 'That was hard!' Because you're saying enough to answer, but not too much. And you don't have any like visual feedback, so it was hard." In the end, she said, the argument felt more like an oral exam than an oral argument. Tom Goldstein, publisher of Scotusblog, had a similar reaction. Goldstein, who has argued 43 cases before the court, said he thought the argument was probably more useful to the public than usual. "But I bet it was less useful for the justices," he said. "Because there was less opportunity to follow up on lines of questions and less opportunity to influence someone ... so there's much less engagement in the oral argument." Still there were no major hitches on this first day. Justice Sonia Sotomayor briefly forget to unmute her phone at one point, prompting a "Sorry, chief." Justice Breyer's voice broke up in static for a second or two. But as Goldstein observes, this was a big change for the court. "Culturally a change, technologically a change. And it could have been a big embarrassment if it didn't go well, but it went fine," he said. "I think they're happy." Copyright 2020 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
take L.A. Philharmonic To Take Over Operations At Ford Theatre By feeds.scpr.org Published On :: Wed, 13 Nov 2019 09:59:22 -0800 Kyle StokesThe L.A. Philharmonic will be the new operator of the John Anson Ford Theatre, the smaller outdoor venue near the 101 Freeway across from the Hollywood Bowl, under a plan approved by the Los Angeles County Board of Supervisors. L.A. funding sustains the Ford, and the county recently spent $80 million renovating the 1,200 seat amphitheater. But attendance has been lackluster — and Supervisor Sheila Kuehl hopes the L.A. Philharmonic can change that. “The Ford will be able to take advantage of the natural synergies in marketing, capacity-building and program resources that simply haven’t been available to the Ford as an independent institution," she said. The move by the L.A. County blindsided many local artists. They say the Ford is an important incubator for diverse talent. They also worry ticket prices will increase. Prompted by their criticism, the Supervisors will require the Phil to meet with artists and annually review the diversity of the Ford’s shows with county officials. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
take Effects of organochlorine pollution on animals take a long time to wear off By Published On :: Thu, 22 Nov 2012 11:49:01 GMT Populations of otters, grey seals and sea eagles are slowly recovering in Sweden, which is likely to be thanks in part to a ban on organochlorine chemicals, such as PCBs and DDT, in the 1970s, according to a new study. However, the research shows that negative effects of these chemicals on the reproductive health of female animals persisted for more than 15 years after the ban was introduced. Full Article
take 5 common password mistakes you should avoid By feedproxy.google.com Published On :: Thu, 07 May 2020 09:30:12 +0000 Password recycling or using easy-to-guess passwords are just two common mistakes you may be making when protecting your digital accounts The post 5 common password mistakes you should avoid appeared first on WeLiveSecurity Full Article Password
take Stemline Shares Take Off on $677 Million Buyout Offer by Global Pharmaceutical Firm By feedproxy.google.com Published On :: Mon, 04 May 2020 00:00:00 PST Source: Streetwise Reports 05/04/2020 Shares of Stemline Therapeutics traded 150% higher after the company reported that it has entered into a definitive agreement to be acquired by Italy's Menarini Group in a deal valued at up to $677 million.Stemline Therapeutics Inc. (STML:NASDAQ), which is focused on developing and commercializing novel oncology therapeutics, today announced that it has entered into a definitive agreement to be acquired by private Italian pharmaceutical and diagnostics company Menarini Group in a transaction valued up to $677 million. The companies advised that the transaction has already been unanimously approved by both companies' Boards of Directors and that the transaction is expected to close in Q2/20 subject to customary closing conditions, regulatory approvals and a tender of at least 50% of the outstanding Stemline shares by shareholders. Menarini stated that it plans to fund the purchase by using existing cash resources. The firms outlined that purchase details and advised that "under the terms of the agreement, a wholly owned subsidiary of the Menarini Group will commence a tender offer for all outstanding shares of Stemline, whereby Stemline shareholders will be offered a total potential consideration of $12.50 per share, consisting of an upfront payment of $11.50 in cash and one non-tradeable Contingent Value Right (CVR) that will entitle each holder to an additional $1.00 in cash per share upon completion of the first sale of ELZONRIS in any EU5 country after European Commission approval." The report explained that ELZONRIS is a novel targeted therapy directed to the interleukin-3 (IL-3) receptor-α (CD123) and was developed by Stemline for treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adult and pediatric patients. The firm stated that the U.S. Food and Drug Administration (FDA) approved that drug in the U.S. in December 2018. A marketing authorization application (MAA) has already been submitted and is presently under review by the European Medicines Agency. Post acquisition, Menarini expects to obtain approvals and expand distribution of ELZONRIS to Europe and emerging markets. Stemline Therapeutics' Chairman, CEO and Founder Ivan Bergstein, M.D., commented, "Joining Menarini represents a unique opportunity for Stemline to advance the commercialization of ELZONRIS across the globe and to accelerate the development of our pipeline of oncology assets. ...We are excited to be combining with a like-minded organization in Menarini, in a transaction that will deliver immediate and significant cash value to our shareholders, while also allowing our shareholders to participate in the future upside of ELZONRIS's European launch." Elcin Barker Ergun, CEO of Menarini Group, remarked, "Stemline is an excellent fit for Menarini, enabling us to expand our presence in the U.S. with an established biopharmaceutical company focused on developing oncology therapeutics. Through this acquisition, we will continue to strengthen our portfolio and pipeline of oncology assets and deliver novel therapies around the world." The company described BPDCN, formerly blastic NK-cell lymphoma, as "an aggressive hematologic malignancy, often with cutaneous manifestations, with historically poor outcomes which typically presents in the bone marrow and/or skin and may also involve lymph nodes and viscera." Stemline Therapeutics is a commercial-stage biopharmaceutical company headquartered in New York that develops and markets oncology therapeutics. The firm stated that its "ELZONRIS® (tagraxofusp) is a targeted therapy directed to CD123 and is FDA-approved and commercially available in the U.S. for the treatment of adult and pediatric patients, two years and older, with BPDCN." Stemline noted that ELZONRIS is also being currently being evaluated in clinical studies for other indications including chronic myelomonocytic leukemia, myelofibrosis and acute myeloid leukemia. The Menarini Group is an international pharmaceutical company based in Italy which operates and sells its products in more than 100 countries. The company stated that it has $4.2 billion in sales annually. The company's medicines address many areas of illnesses including cardiovascular, gastroenterology, metabolic, infectious diseases and anti-inflammatory/analgesic therapeutic areas and oncology. Stemline Therapeutics began the day with a market capitalization of around $249.2 million with approximately 54.27 million shares outstanding and a short interest of about 11.3%. STML shares opened nearly 150% higher today at $11.81 (+$7.06, +148.63%) over Friday's closing price of $4.75. The stock has traded today between $1.81 and $12.35 per share and is currently trading at $12.10 (+$7.35, +154.74%). Sign up for our FREE newsletter at: www.streetwisereports.com/get-news Disclosure: 1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None. 2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees. 3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. 4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports. 5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases. 6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice. ( Companies Mentioned: STML:NASDAQ, ) Full Article
take More information and training on green public procurement could increase its uptake By ec.europa.eu Published On :: Thu, 6 Dec 2012 12:09:50 GMT Public authorities in EU Member States are encouraged to purchase more environmentally-friendly goods and services through Green Public Procurement (GPP). A recent survey of purchasing managers in Italy has identified some factors that influence their adoption of this strategy, and suggests that a broad knowledge of GPP is key to its implementation. Full Article
take Local food collectives: what role should public authorities take? By ec.europa.eu Published On :: Thu, 20 Mar 2014 9:23:19 GMT Local food systems, such as vegetable box schemes or farmers' markets, can encourage sustainable consumption. However, authorities must take care before becoming too involved in such citizen-led initiatives, because these collectives may be wary of government intervention, a new study suggests. Full Article
take New insights into uptake of household flood mitigation measures By ec.europa.eu Published On :: Thu, 12 Sep 2013 11:50:43 +0100 Comprehensive flood risk management should include household measures, such as improving a home’s stability and relocating heating systems to safe places within the house. According to new research, better communication with householders by authorities on the effectiveness of such measures, and how to implement them, could increase their uptake. Full Article
take Managing flood risk: more realistic models need to take account of spatial differences By ec.europa.eu Published On :: Thur, 19 April 2018 9:23:19 GMT Effective flood-risk management requires accurate risk-analysis models. Conventional analysis approaches, however, are based on the evaluation of spatially homogenous scenarios, which do not account for variation in flooding across a river reach/ region. Since flood events are often spatially heterogeneous (i.e. unevenly distributed), this paves the way for error. Now, scientists have developed a novel framework for risk analysis that accounts for their heterogeneity, and successfully demonstrated the accuracy of the approach by applying it in a proof-of-concept exercise in Vorarlberg, Austria. By facilitating improved prediction and quantification of flood events, this model is likely to inform future flood-risk management and related decision-making. Full Article
take Wild insects could take over the pollinating role of honeybees By ec.europa.eu Published On :: Thu, 26 Nov 2009 10:21:02 GMT Scientists have identified several wild insects that could undertake the crop pollination function of honeybees. By comparing a range of pollinating insects they found three wild species that appear to be as efficient as the honeybee in pollination but may need management to increase their numbers. Full Article
take Influences on uptake of agri-environmental schemes in Spain By ec.europa.eu Published On :: Thu, 14 Oct 2010 15:24:21 +0100 New research in southern Spain has studied what influences participation in agri-environmental schemes (AES). It indicated that the uptake of schemes that involve a major change in farm practices depends on the farm structure, whereas for schemes with minor changes, individual farmer characteristics play a greater role. Full Article
take When can science help conflicting stakeholders reach agreement? By ec.europa.eu Published On :: Thu, 20 Mar 2014 9:23:19 GMT Does scientific evidence always help conflicting stakeholders to reach agreement on how to deal with environmental risks? Scientists have now developed a mathematical framework to help answer this question. They show that stakeholder perceptions of the costs and benefits of regulations, as well as their perceptions of the quality of new research, will determine whether they change their standpoint. Full Article
take How bridging organisations aid design and uptake of EU agri-environment schemes By ec.europa.eu Published On :: Tues, 27 June 2017 9:23:19 GMT Managing landscapes effectively requires the involvement of a wide variety of stakeholders. The views and interests of these different groups can be effectively integrated by agri-environment 'collaboratives' — a type of bridging organisation which can be found in varying forms in Europe. Using data from Germany and the Netherlands, a study concludes that these groups make important contributions to landscape management, ranging from implementing policy to generating income. Full Article
take Refurbished mobile phones: consumer perceptions and how to increase uptake By ec.europa.eu Published On :: Thu, 03 Mar 2016 09:12:34 GMT A recent survey of Dutch mobile phone owners has identified why some consumers buy refurbished mobile phones while others buy new ones. Some consumers perceived refurbished phones to be inferior, which was a major barrier to their purchase. The study’s authors make a number of recommendations to increase consumer uptake of refurbished mobile phones, including promoting the financial and environmental benefits and offering warranties. Full Article
take Vista Equity Partners to invest Rs 11,367 crore in Jio Platforms for 2.32% stake By cio.economictimes.indiatimes.com Published On :: 2020-05-08T09:11:54+05:30 With the latest deal, Jio Platforms is set to net a combined Rs 60,596 crore for the unit of Reliance Industries which comprises mainly its telecom business under Reliance Jio Infocomm Full Article
take Climate-smart agri-technology innovations: how to increase uptake By ec.europa.eu Published On :: Thu, 14 Apr 2016 09:12:34 GMT ‘Climate-smart agriculture’ aims to sustainably increase agricultural production and increase resilience to climate change. One aspect focuses on climate-smart technologies. This study interviewed users and producers of these technologies, highlighting barriers to adoption and possible means of overcoming them, including increasing awareness, user-focused design and changes to policy. Full Article
take Time to take stock of marine and coastal assets By ec.europa.eu Published On :: Thu, 25 Feb 2010 15:41:29 GMT A new study highlights the economic importance of coastal and marine areas and the urgent need to develop concrete methods for assessing their value. Researchers say the need is especially strong now as climate change's impacts could reduce the economic value of coastal and marine environments. Full Article
take Coastal ecosystem services’ valuation by stakeholders improves planning decisions By ec.europa.eu Published On :: Thu, 02 Oct 2014 9:23:19 GMT A framework to value marine and coastal zone ecosystem services, which acknowledges but transcends monetary value, has been proposed by researchers. Using this approach, coastal managers can integrate the different values placed on ecosystem goods and services by various stakeholders to assess how these values affect planning decisions. Full Article
take Selection of policy options to encourage take-up of low-carbon transport assessed By ec.europa.eu Published On :: Thu, 25 Jul 2013 14:34:33 +0100 A ‘feebate’ can be an effective policy option to aid the transition to a more environmentally-friendly transport system, a UK study suggests. This combination of fees and rebates can increase the take-up of low-carbon cars, the researchers argue, which leads to reduced life cycle greenhouse gas (GHG) emissions. Full Article
take Collaboration between stakeholders in sustainable forest management By ec.europa.eu Published On :: Thu, 7 Oct 2010 11:42:54 +0100 New research on sustainable forest management (SFM) initiatives in Russia and Sweden has indicated that the main challenges to SFM are combining top-down and bottom up approaches to management, coordinating the different sectors involved and including all actors and stakeholders. Full Article
take Mutual trust between coastal stakeholders key to successful climate change adaptation By ec.europa.eu Published On :: Thu, 02 Oct 2014 9:23:19 GMT A lack of trust between stakeholders, planners and decision makers in coastal Portugal is obstructing adaptation to climate change plans, finds a new study. The researchers suggest that building trust between stakeholders and coastal managers could lead to improved participation and dialogue for future planning, financing and implementation of coastal adaptation. Full Article
take Simple steps to increase the uptake of sustainable service-based business models By ec.europa.eu Published On :: Thu, 14 Apr 2016 09:12:34 GMT ‘Product-service systems’ are innovative business models designed to satisfy societal needs in an environmentally sustainable manner. This study explores how government policies could increase the uptake of these systems, outlining five key recommendations to achieve this, including schemes to raise awareness and involve local authorities. Full Article
take Cloud-based flood risk learning tool engages multiple stakeholders By ec.europa.eu Published On :: Thu, 01 October 2015 9:23:32 GMT A pilot cloud-based learning platform that brings together multiple datasets, models and visualisation tools has been developed with the engagement of numerous stakeholders throughout the design process. This tool could lead to informed decisions about flood risk at the local level. These types of tools and frameworks are effective ways of facilitating better decision making. Full Article
take Covid-19 impact: Jeff Bezos takes back the wheel at Amazon By cio.economictimes.indiatimes.com Published On :: 2020-04-23T17:33:45+05:30 After years of working almost exclusively on long-term projects and pushing day-to-day management to his deputies, Bezos, 56, has turned back to the here-and-now problems facing Amazon, the company said, as the giant retailer grapples with a surge of demand, labor unrest and supply chain challenges brought on by the coronavirus. Full Article
take Facebook takes aim at Zoom with video chat upgrade By cio.economictimes.indiatimes.com Published On :: 2020-04-25T08:43:06+05:30 Facebook on Friday unveiled a new video chat service with virtual "rooms" where people can pop in to visit friends, aiming at users turning to the popular Zoom platform during the pandemic. Full Article
take Take user privacy seriously, don't collect data without consent: Xiaomi By cio.economictimes.indiatimes.com Published On :: 2020-05-03T11:22:34+05:30 Xiaomi India Managing Director said that the company does not collect any user data that the user has not explicitly given permission or consent to. He added that in the browser's incognito mode, all user data is completely encrypted and anonymised. He also pointed out that all Mi Browser and Mi Cloud data of Indian users is stored locally in AWS servers in India. Full Article
take Virus takes a toll on blue collar staff; no pay for 12 crore By cio.economictimes.indiatimes.com Published On :: 2020-04-28T12:15:00+05:30 Jobs are also expected to nosedive in the remaining quarters of the year unless demand picks up by the festive season later this year, experts tracking the sector said. Travel, hospitality, tourism, aviation, retail, outdoor entertainment, food and beverages and real estate sectors have been hit the most, staffing agency TeamLease said. Full Article