Title: Many Who Need Opioid OD Antidote the Most Can't Afford It
Category: Health News
Created: 8/22/2022 12:00:00 AM
Last Editorial Review: 8/22/2022 12:00:00 AM

Title: Organ From Live Donor Best When Child Needs New Kidney
Category: Health News
Created: 8/17/2022 12:00:00 AM
Last Editorial Review: 8/18/2022 12:00:00 AM

Background:

Continuous glucose monitoring (CGM) for patients with type 1 and type 2 diabetes is associated with improved clinical, behavioral, and psychosocial patient health outcomes and is part of the American Diabetes Association’s Standards of Medical Care. CGM prescription often takes place in endocrinology practices, yet 50% of adults with type 1 diabetes and 90% of all people with type 2 diabetes receive their diabetes care in primary care settings. This study examined primary care clinicians’ perceptions of barriers and resources needed to support CGM use in primary care.

Purpose The posterior superior alveolar (PSA) block injection is one of many techniques used to provide profound anesthesia for invasive dental procedures. This technique has a high success rate but is not without complication risks. The purpose of this study was to determine if pulpal anesthesia of the maxillary second molar could be achieved using a reduced needle depth of 10mm or 5mm compared to the traditional needle depth of 16mm.Methods Sixty participants were asked to participate in three sessions. Each session started with a pre neural response test, followed by one randomized needle depth PSA injection, and ending with a post neural response test. The neural response test consisted of two parts, a cold refrigerant and a dental probe, on the buccal and interproximal surface of the maxillary second molar. After receiving a positive neural response, each participant received a posterior superior alveolar block injection using a short (21mm), 27-gauge dental needle with a randomized needle penetration depth of 16mm, 10mm, or 5mm. A post neural response test consisting of the same two parts as the pre-test was conducted on the maxillary second molar to evaluate for profound anesthesia.Results Positive neural responses were obtained from 100% of the participants (n=167) during the pre-tests. Study results demonstrated an 85% success rate at the traditional 16mm needle depth and a 93% and 92% success rates for the reduced needle depths of 10mm and 5mm, respectively. Pulpal anesthesia of the maxillary second molar had been achieved at all three needle depths with no statistically significant difference in the rate of success. Furthermore, there were no adverse events observed.Conclusion The reduced needle depth technique showed promise in achieving desired results of pulpal anesthesia with a reduced risk for complications associated with the PSA block injection. Additional studies are recommended to achieve evidence-based support for this reduced needle depth technique.

BACKGROUND AND PURPOSE:

Recently, artificial intelligence tools have been deployed with increasing speed in educational and clinical settings. However, the use of artificial intelligence by trainees across different levels of experience has not been well-studied. This study investigates the impact of artificial intelligence assistance on the diagnostic accuracy for intracranial hemorrhage and large-vessel occlusion by medical students and resident trainees.

Affibody molecules are small, robust, and versatile affinity proteins currently being explored for therapeutic, diagnostic, and biotechnological applications. Surface-exposed residues on the affibody scaffold are randomized to create large affibody libraries from which novel binding specificities to virtually any protein target can be generated using combinatorial protein engineering. Affibody molecules have the potential to complement—or even surpass—current antibody-based technologies, exhibiting multiple desirable properties, such as high stability, affinity, and specificity, efficient tissue penetration, and straightforward modular extension of functional domains. It has been shown in both preclinical and clinical studies that affibody molecules are safe, efficacious, and valuable alternatives to antibodies for specific targeting in the context of in vivo diagnostics and therapy. Here, we provide a general background of affibody molecules, give examples of reported applications, and briefly summarize the methodology for affibody generation.

BackgroundLong-term health conditions are major challenges for care systems. Social prescribing link workers have been introduced via primary care networks (PCNs) across England since 2019 to address the wider determinants of health by connecting individuals to activities, groups, or services within their local community.AimTo assess whether the rollout of social prescribing link workers was in areas with the highest need.Design and settingA retrospective study of social prescribing link workers in England from 2019 to 2023.MethodWorkforce, population, survey, and area-level data at the PCN-level from April 2020 to October 2023 were combined. Population need before the rollout of link workers was measured using reported lack of support from local services in the 2019 General Practice Patient Survey. To assess if rollout reflected need, linear regression was used to relate provision of link workers (measured by full-time equivalent [FTE] per 10 000 patients) in each quarter to population need for support.ResultsPopulations in urban, more deprived areas and with higher proportions of people from minority ethnic groups had the highest reported lack of support. Geographically these were in the North West and London. Initially, there was no association between need and provision; then from July 2022, this became negative and significant. By October 2023, a 10-percentage point higher need for support was associated with a 0.035 (95% confidence interval = −0.634 to −0.066) lower FTE per 10 000 patients.ConclusionRollout of link workers has not been sufficiently targeted at areas with the highest need. Future deployments should be targeted at those areas.

BackgroundMost people with type 2 diabetes receive treatment in primary care by GPs who are not specialised in diabetes. Thus, it is important to uncover the most essential information needs regarding type 2 diabetes in general practice.AimTo identify information needs related to type 2 diabetes for GPs.Design and settingSystematic review focused on literature relating to Western countries.MethodMEDLINE, Embase, PsycInfo and CINAHL were searched from inception to January 2024. Two researchers conducted the selection process, and citation searches were performed to identify any relevant articles missed by the database search. Quality appraisal was conducted with the Mixed Methods Appraisal Tool. Meaning units were coded individually, grouped into categories, and then studies were summarised within the context of these categories using narrative synthesis. An evidence map was created to highlight research gaps.ResultsThirty-nine included studies revealed eight main categories and 36 subcategories of information needs. Categories were organised into a comprehensive hierarchical model of information needs, suggesting ‘Knowledge of guidelines’ and ‘Reasons for referral’ as general information needs alongside more specific needs on ‘Medication’, ‘Management’, ‘Complications’, ‘Diagnosis’, ‘Risk factors’, and ‘Screening for diabetes’. The evidence map provides readers with the opportunity to explore the characteristics of the included studies in detail.ConclusionThis systematic review provides GPs, policymakers, and researchers with a hierarchical model of information and educational needs for GPs, and an evidence map showing gaps in the current literature. Information needs about clinical guidelines and reasons for referral to specialised care overlapped with needs for more specific information.

In August, fellow reporter Jason Patinkin and I crossed on foot from northern Uganda into rebel-held South Sudan. Over the course of four days, we walked more than 40 miles through the bush, escorted by rebel soldiers, to shed light on one of the world’s most underreported conflicts.

Reporting on South Sudan’s war, which began in 2013, has always been a challenge due to the risk and logistical hurdles associated with accessing remote areas where fighting takes place. But over the past year, covering the war and its humanitarian fallout has become particularly difficult. Since the beginning of this year, South Sudan’s government has banned at least 20 foreign journalists in an apparent effort to silence reporters who had a track record of critically reporting on the government.

This systematic crackdown on the foreign press (South Sudanese journalists have long risked imprisonment and death for doing their work) coincided with two important developments. In November 2016, the United Nations warned that the violence being committed against civilians in the southern region of Equatoria risked spiraling into genocide. Then, in February, the UN declared a man-made famine, warning that 100,000 people were at risk of starving to death as a result of civil war.

Journalists seeking to cover these events were left with two equally unsavory options: self-censorship or a risky trip to rebel-held parts of the country. Only a handful of journalists have attempted the latter since fighting escalated in July last year. For us, this was our second embed with the rebels this year.

We set off from a town in northern Uganda at five in the morning, bouncing along a bumpy dirt track towards the South Sudan border. Crammed into our four-wheel drive were rebel commander Martin Abucha, a dual American and South Sudanese citizen who we planned to profile for our PBS NewsHour Weekend segment, a couple of guides, and several duffle bags stuffed with our tents, sleeping bags, emergency medical kits and provisions to last us four days.

Just as the sun began to rise above a distant range of hills that we aimed to cross later that day, our car came to a halt in front of a stream. Because of the rainy reason, it carried more water than usual. It was time to disembark and start walking, or “footing,” as South Sudanese tend to call it.

We took off our shoes and waded through the stream’s chilly waters. This was the first of a many rivers we’d have to cross along the way, either on foot or in small flimsy canoes dug out from tree trunks. Each time, we dreaded the idea of falling in with our camera gear.

The first part of our journey in northern Uganda felt very much like a hike through a national park. Passing beautiful landscapes and idyllic farming villages, one could almost forget we were headed into a war zone — but we were about to get a reality check.

We had just crossed into South Sudan when out of nowhere, two dozen armed men popped out of the tall grass and surrounded us at gunpoint.

“Stop! Who are you and where are you going?” a soldier called out in Juba Arabic from his hideout no more than 20 yards away, pointing his AK47 at us. Another one next to him had a rocket-propelled grenade propped on his shoulder, also unequivocally aiming it in our direction.

Instinctively, we threw our hands in the air and exchanged a baffled glance. Had we accidentally bumped into government soldiers? Or perhaps we had come onto the “wrong” rebels? Abucha’s group, called the Sudan People’s Liberation Army In Opposition, is the biggest but not the only armed group in Equatoria, an area rife with rival militia and bandits who exploit the security vacuum left by war.

To our relief, and only after Abucha answered a series of questions, this routine security check quickly gave way to a warm welcome. The platoon would be our escort for the next four days as we trekked to their base and to Loa, Abucha’s hometown.

Keeping up with the rebels was no easy task. Given the country’s pervasive lack of basic infrastructure, South Sudanese grow up walking for dozens of miles just to go about their daily lives. For sedentary Westerners, keeping the target pace of “two meters per second” (around five miles an hour) proved challenging amid 90-degree temperatures, all while filming and plowing our way through dense, itchy elephant grass.

The upside of the cumbersome terrain was that it kept us safe. During our four-day trip, we didn’t cross a single road, instead walking along a dizzying network of narrow bush paths the rebels seemed to know like the backs of their hands. An unwanted encounter with government troops, who tended to stick to roads and move around in vehicles as opposed to on foot, was highly unlikely.

The closest we got to government-controlled area was a visit to Loa, located just two kilometers away from a main road frequently patrolled by government soldiers. We couldn’t stay long, but the hour we spent on the ground offered us a glimpse into what villages must look like in many parts of Equatoria: burned mud huts, looted schools and clinics, fallow fields and – most strikingly – no civilians.

The war has had a devastating impact on South Sudanese communities like the one in Loa, but much of it has remained out of the limelight of international media. Our four-day venture into rebel-held South Sudan offered us a rare opportunity to report ground truths, and we are thankful for that.

The post Column: Why reporting from South Sudan is so difficult — and critically needed appeared first on PBS NewsHour.

Up to 650 houses could be built on land at the golf club

It's been a week full of news, some exciting, some alarming. Chris breaks the site...repeatedly. Kelley comes to terms with the fact mowing the lawn is hard in real life. Josh explains Japanese tabloid scandals. Anna Marie assigns a tedious task to Pascal.

The post RPG Cast – Episode 594: “The Queen Needs a Monster Rig” appeared first on RPGamer.

Chris's 3DS battery is swol. Johnathan educates us on the retro market. Kelley poopsocks like a three-legged kitten. While Josh waxes poetic about his Madden otome dating sim.

The post RPG Cast – Episode 640: “Does Your Task Bar Need Fiber?” appeared first on RPGamer.

Congested Kelley goes HONK! Chris runs over old people in GTA while distracting Anna Marie with Octopath. RPGamer tip of the week: If your game has more than 12 currencies, it's main stream.

The post RPG Cast – Episode 643: “Kinky Chemical Engineer” appeared first on RPGamer.

Chris gets trolled by the bear cave. Jason sets optics to stun. Josh is hiding in a rest stop bathroom. Kelley stretches harder than she did for The Witch and the Hundred Knight. Also, find out how to increase your poop by 10 and express your opinions about Dragon Quest Soundtracks.

The post RPG Cast – Episode 664: “We Need to Talk About Gambit” appeared first on RPGamer.

After 25 years in orbit, the Chandra X-ray Observatory is under threat. We need to protect this monument to human ingenuity, argues Chanda Prescod-Weinstein

Medically evacuating an astronaut from space is difficult and expensive, and a new model predicts that one in three long-duration moon missions may require it

As misinformation about the upcoming US elections rockets across social media, creating chaos, companies need to be honest about where this content is coming from, says Annalee Newitz

Feedback digs into a baffling ad for a mobile game and identifies a new and devilish way to advertise a product online: make it as confusing as possible to encourage people to click (it worked on Feedback)

EA FC 25 players can snag some big freebies this week, with EA Sports celebrating the Ballon d'Or in style for all Ultimate Team players with some of the best players around.

Black Ops 6 is here, and fans have been itching to know what's included in Season 1 - and now we have an answer. Here's what's included, and when you can play

The Adison Vein Locator gives medical professionals Superman-like X-ray vision for finding patients' veins for easy insertion of needles.

As our submersible descended, the waters grew darker around us. Looming teeth, some as long as a man’s leg, skirted the edge of our floodlights. The captain was sure this area held caves filled with golden bounty, but to those creatures of the deep it was our flesh and blood that were the true prizes… […]

How private is your internet address? Very, says the Supreme Court of Canada. Police can’t just walk into a company and demand a suspect’s IP address by saying a Canadian resident doesn’t have an expectation of privacy of that information, the court ruled today. An IP address is vital enough that every resident expects it […]

In Canada, your IP address has the right to remain silent. Elon Musk is suing OpenAI for not being Open. Apple faces a class action not allowing competitive access to backup services and the World Server Throwing Competition in March 2024 is accused of being too violent towards servers.   All this and more on the […]

Two pioneers of artificial intelligence have won the Nobel Prize in physics for discoveries and inventions that formed the building blocks of machine learning.

The World Health Organization has declared mpox a public health emergency of international concern – a new variant of the virus has caused an outbreak in Central and West Africa and spread to Sweden

Wastewater is a major reservoir for antibiotic resistance genes, but modified bacteria can chop up this DNA before the dangerous microbes reach people

Robert F. Kennedy Jr. launched a "Nominees for the People" forum to crowdsource 4,000 positions in the Trump administration to Make America Healthy Again.

The future of engineering is bright, and it’s being shaped by the young minds at the TryEngineering Summer Institute (TESI), a program administered by IEEE Educational Activities. This year more than 300 students attended TESI to fuel their passion for engineering and prepare for higher education and careers. Sessions were held from 30 June through 2 August on the campuses of Rice University, the University of Pennsylvania, and the University of San Diego.

The program is an immersive experience designed for students ages 13 to 17. It offers hands-on projects, interactive workshops, field trips, and insights into the profession from practicing engineers. Participants get to stay on a college campus, providing them with a preview of university life.

Student turned instructor

One future innovator is Natalie Ghannad, who participated in the program as a student in 2022 and was a member of this year’s instructional team in Houston at Rice University. Ghannad is in her second year as an electrical engineering student at the University of San Francisco. University students join forces with science and engineering teachers at each TESI location to serve as instructors.

For many years, Ghannad wanted to follow in her mother’s footsteps and become a pediatric neurosurgeon. As a high school junior in Houston in 2022, however, she had a change of heart and decided to pursue engineering after participating in the TESI at Rice. She received a full scholarship from the IEEE Foundation TESI Scholarship Fund, supported by IEEE societies and councils.

“I really liked that it was hands-on,” Ghannad says. “From the get-go, we were introduced to 3D printers and laser cutters.”

The benefit of participating in the program, she says, was “having the opportunity to not just do the academic side of STEM but also to really get to play around, get your hands dirty, and figure out what you’re doing.”

“Looking back,” she adds, “there are so many parallels between what I’ve actually had to do as a college student, and having that knowledge from the Summer Institute has really been great.”

She was inspired to volunteer as a teaching assistant because, she says, “I know I definitely want to teach, have the opportunity to interact with kids, and also be part of the future of STEM.”

More than 90 students attended the program at Rice. They visited Space Center Houston, where former astronauts talked to them about the history of space exploration.

Participants also were treated to presentations by guest speakers including IEEE Senior Member Phil Bautista, the founder of Bull Creek Data, a consulting company that provides technical solutions; IEEE Senior Member Christopher Sanderson, chair of the IEEE Region 5 Houston Section; and James Burroughs, a standards manager for Siemens in Atlanta. Burroughs, who spoke at all three TESI events this year, provided insight on overcoming barriers to do the important work of an engineer.

Learning about transit systems and careers

The University of Pennsylvania, in Philadelphia, hosted the East Coast TESI event this year. Students were treated to a field trip to the Southeastern Pennsylvania Transportation Association (SEPTA), one of the largest transit systems in the country. Engineers from AECOM, a global infrastructure consulting firm with offices in Philadelphia that worked closely with SEPTA on its most recent station renovation, collaborated with IEEE to host the trip.

The benefit of participating in the program was “having the opportunity to not just do the academic side of STEM but also to really get to play around, get your hands dirty, and figure out what you’re doing.” — Natalie Ghannad

Participants also heard from guest speakers including Api Appulingam, chief development officer of the Philadelphia International Airport, who told the students the inspiring story of her career.

Guest speakers from Google and Meta

Students who attended the TESI camp at the University of San Diego visited Qualcomm. Hosted by the IEEE Region 6 director, Senior Member Kathy Herring Hayashi, they learned about cutting-edge technology and toured the Qualcomm Museum.

Students also heard from guest speakers including IEEE Member Andrew Saad, an engineer at Google; Gautam Deryanni, a silicon validation engineer at Meta; Kathleen Kramer, 2025 IEEE president and a professor of electrical engineering at the University of San Diego; as well as Burroughs.

“I enjoyed the opportunity to meet new, like-minded people and enjoy fun activities in the city, as well as get a sense of the dorm and college life,” one participant said.

Hands-on projects

In addition to field trips and guest speakers, participants at each location worked on several hands-on projects highlighting the engineering design process. In the toxic popcorn challenge, the students designed a process to safely remove harmful kernels. Students tackling the bridge challenge designed and built a span out of balsa wood and glue, then tested its strength by gradually adding weight until it failed. The glider challenge gave participants the tools and knowledge to build and test their aircraft designs.

One participant applauded the hands-on activities, saying, “All of them gave me a lot of experience and helped me have a better idea of what engineering field I want to go in. I love that we got to participate in challenges and not just listen to lectures—which can be boring.”

The students also worked on a weeklong sparking solutions challenge. Small teams identified a societal problem, such as a lack of clean water or limited mobility for senior citizens, then designed a solution to address it. On the last day of camp, they pitched their prototypes to a team of IEEE members that judged the projects based on their originality and feasibility. Each student on the winning teams at each location were awarded the programmable Mech-5 robot.

Twenty-nine scholarships were awarded with funding from the IEEE Foundation. IEEE societies that donated to the cause were the IEEE Computational Intelligence Society, the IEEE Computer Society, the IEEE Electronics Packaging Society, the IEEE Industry Applications Society, the IEEE Oceanic Engineering Society, the IEEE Power & Energy Society, the IEEE Power Electronics Society, the IEEE Signal Processing Society, and the IEEE Solid-State Circuits Society.

Yes, you can nail your own pedicure! But you'll need more than just nail varnish and toenail clippers.

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We spoke to the Conservative MP and former army officer Tom Tugendhat, who served in Iraq and Afghanistan.

The business secretary Jonathan Reynolds has called for a change of culture at the Post Office, as he gave evidence to the inquiry into the Horizon scandal.

Dry ice is becoming an essential resource for various industries in Lakeland, Florida. Made from carbon dioxide in its solid form, dry ice sublimates directly into gas without leaving any liquid residue. This characteristic makes it a highly effective cooling solution, ideal for transporting perishable goods, supporting medical needs, and industrial cleaning. With the right […]

The post Essential Guide to Choosing the Best Lakeland Dry Ice Supplier for Your Business Needs appeared first on Chart Attack.

Ever found yourself at a party with the usual chips and pretzels, wishing for something more exciting? Well, it’s time to elevate your snacking game. There’s a world of flavors waiting to be discovered, and some of them are so unique that they belong on your bucket list. Sometimes, finding rare treats can be tricky. […]

The post Top 15 Exotic Snacks You Need to Try Before You Die – A Flavorful Bucket List appeared first on Chart Attack.

Republicans need a "bold Senate GOP leader," Sen. Mike Lee (R-UT) said on Tuesday as three Republican senators -- Sen. Rick Scott (R-FL), Senate Republican Whip John Thune (R-SD), and Sen. John Cornyn (R-TX) -- vie for the position of Senate Majority Leader.

The post Sen. Mike Lee: ‘We Need a Bold Senate GOP Leader’ appeared first on Breitbart.

Team at Kolkata institute engineers bacteria to solve maths problems  The Hindu

Although Avneet hasn’t confirmed any involvement in the film, fans are hopeful this could mark her Hollywood debut, following in the footsteps of Anil Kapoor, who appeared in ‘Mission: Impossible — Ghost Protocol’ in 2011

Calgary Flames right-winger Anthony Mantha will miss the rest of the NHL season with a knee injury, the team announced Monday.

Harvest Moon: Home Sweet Home has been a very interesting game to follow pre-release. I say this not only because …

Continue reading "‘Harvest Moon: Home Sweet Home’ iOS Review – A Great Start, but Needs More Work"

The jury also decided to hold a Virginia-based military contractor responsible for contributing to the torture and mistreatment of detainees at the notorious Iraqi prison two decades ago.

Social distancing, shelter-in-place, lockdown, quarantine:  the global coronavirus outbreak has made these terms part of daily usage. Governments and health organisations across the world are recommending social distancing. It is ...

The post Social distancing need not mean social isolation appeared first on Star Observer.

Discover the calming power of a worry stone! Learn how this ancient tool relieves stress, boosts mindfulness, and promotes emotional balance through touch.

And the Senate shouldn’t abandon its ‘advice and consent’ role.

It is difficult to disentangle Russian and Chinese scientists from international science cooperation. That is a good thing

Today’s cannabis plant is highly cultivated and incredibly potent. Treating it like a commodity, and not a testable, regulated medicine, is hurting people