cor

Securiti launches Gencore AI solution to build secure artificial intelligence systems

Gencore AI provides the same capability for the safe construction of AI tools that their core platform has provided from its inception.




cor

'Sage' of Omaha Buffett cuts Apple stake, boosting cash holding to record level

'Sage' of Omaha Buffett cuts Apple stake, boosting cash holding to record level




cor

Austrian pilot breaks world's longest wingsuit flight records

Austrian pilot breaks world's longest wingsuit flight records




cor

Austrian team sets record at top of Swiss Verzasca dam

Austrian team sets record at top of Swiss Verzasca dam




cor

X Empire Hits Record All-Time High: Can It Sustain the Current Momentum?

For the first time after the launch in late October, X Empire has entered an upward trend hitting the all-time high after weeks of long downturn. The token has been underperforming in the crypto market since it was introduced to the ecosystem. Now it has reached its all-time high of $0.0002165. X Empire, id officially [...]




cor

Discord terrorist known as “Rabid” gets 30 years for preying on kids

FBI considers 764 terror network a top threat to kids online.




cor

T-Mobile Breaks Upload Speed Record with New 5G Dual Connectivity

T-Mobile has claimed a new world record in 5G upload speeds, achieving an impressive 2.2 Gbps in tests conducted at California's SoFi Stadium. Partnering with Ericsson and Qualcomm, the telecommunications firm leveraged an emerging technology, 5G Dual Connectivity (5G DC), which combines mid-band and millimeter-wave (mmWave) spectrum bands.






cor

Record labels unhappy with court win, say ISP should pay more for user piracy

Music companies appeal, demanding payment for each song instead of each album.




cor

From Dissipating Clouds to Record-Setting Areas of Drought, the State of the Climate in 2023 Was Shockingly Severe

Part 3 of a three-part series summarizing the findings of a new and unsettling report on climate change.




cor

The Heat Goes On: New Details Emerge About the Extent and Severity of Record-Setting Global Warmth

Part 2 of a three-part series summarizing the findings of a new and unsettling report on climate change.




cor

Earth Just Had its 15th Straight Month of Record Setting Temperatures

It was the hottest August in records dating back to the 1800s — and the heat goes on.




cor

What The Jet Stream And Climate Change Had To Do With The Hottest Summer On Record

The Eastern U.S. started summer 2024 under a record-breaking heat dome, leaving many outdoor workers struggling with the heat.




cor

We Barely Caught a Break From Record-Setting Heat Last Month. Meanwhile, a U.N. Report Pleads, "No More Hot Air, Please!"

Despite a sliver of good news in the latest monthly climate analyses, global heating continues — and the world is far from taming it.




cor

Redecor Codes – November 2024

Find the latest Redecor Codes here! Keep reading for more.




cor

The "Synergistic Core" of the Human Brain?

Are synergistic interactions the fundamental drivers of complex cognition?




cor

Recording Brain Activity Through the Mouth

Neuroscientists introduce a new tool to detect hippocampal activity.




cor

A Curiously Written Coronavirus Paper

The mystery of "extreme acute respiratory syndrome"




cor

Corrosion Control and Surface Finishing Environmentally Friendly Approaches

Location: Electronic Resource- 




cor

Recent Advances on Mycorrhizal Fungi

Location: Electronic Resource- 




cor

ICANN: Keep the Core Neutral, Stupid

ICANN's travelling circus meets in San Juan, Puerto Rico this week. One of the main subjects of discussion has been the introduction of new generic Top-Level Domains (gTLDs), after a GNSO Report proposed 19 "Recommendations" for criteria these new domain strings should meet -- including morality tests and "infringement" oppositions.

I spoke at a workshop on free expression. (another report) It's important to keep ICANN from being a censor, or from straying beyond its narrow technical mandate. The thick process described in the GNSO report would be expensive, open to "hecklers' vetos," and deeply political.

Instead, I recommended that, along the lines of David Isenberg's Stupid Network, ICANN should aim for a "stupid core": approve strings after a minimal test for direct or visual collision. Just as we couldn't predict what applications or content would be successful on the Internet, but benefit from the ease with which innovators can experiment with a wide range, we'll benefit if entrepreneurs can experiment with new TLDs without a lot of central pre-screening. Rather than supporting a race to the bottom to adopt restrictions on the lines of the most restrictive government views of permissible expression (no human rights, sexuality, or "hate"), we must leave it to the governments to apply those restrictions at the edges too, in their own jurisdictions if they insist, but not at the center on all.

Of course I do not support government censorship even at the local level, but between local control, which can itself be a source of experimentation, and central control, which becomes ossified and restrictive at the lowest level, I think local law poses less threat to global free expression. If you agree that ICANN should keep moral judgments out of the DNS root, sign the petition to Keep the Core Neutral.




cor

Siyāsat-i jināyī-i Afghānistān dar qibāl-i zanān-i bazahʹyīdah dar partaw-i asnād-i bayn al-milal = Criminal policy of Afghanistan on the women victims in accordance with the international documents

Location: Main Library- HV6250.4.W65N78 2011




cor

Federal prisoners in jails, 1929-30. A supplement to the Annual report of the federal penal and correctional institutions for the fiscal year ending June 30, 1930.

Location: Government Information - J 16.1:929-30/SUPP.




cor

Children in custody : advance report on the juvenile detention and correctional facility census of 1972-73.

Location: Government Information - J 1.42/3:SD-JD-2




cor

At the core and in the margins : incorporation of Mexican immigrants in two rural Midwestern communities

Location: Electronic Resource- 




cor

Animal Coronaviruses

Location: Electronic Resource- 




cor

Minnesota ranks second in the nation for highest corporate tax rate

(The Center Square) – Minnesota’s top marginal corporate tax rate, 9.8%, is the second-highest the nation, according to an analysis the Tax Foundation released Tuesday.




cor

King Sargon Inc. [Record Label | Music Production | Publishi...

King Sargon Inc. [Record Label | Music Production | Publishing | Promotion]



  • Assyrian Fine Arts Network

cor

Yodel’s new investment “underscores long-term commitment to more sustainable deliveries”

UK independent parcel carrier, Yodel, has opened a brand-new 162,000 sq. ft. depot in Huyton, Liverpool.




cor

Billionaires Are Piling Into an Index Fund That Could Soar Up to 1,207% by 2030, According to Wall Street Experts




cor

Coronavirus Is Not Passed From Mother to Child Late In Pregnancy

Coronavirus Is Not Passed From Mother to Child Late In Pregnancy

After a newborn (born to a mother infected with the 2019 novel coronavirus disease (COVID-19) testing positive for COVID-19 infection within 36 hours of birth, there were concerns about whether the virus could be contracted in the womb. A new study finds that COVID-19 does not pass to the child while in the womb. The women in the small study were from Wuhan, China, in the third trimester of pregnancy and had pneumonia caused by COVID-19. However, it only included women who were late in their pregnancy and gave birth by caesarean section. 

There were two cases of fetal distress but all nine pregnancies resulted in live births. That symptoms from COVID-19 infection in pregnant women were similar to those reported in non-pregnant adults, and no women in the study developed severe pneumonia or died.

All mothers in the study were aged between 26-40 years. None of them had underlying health conditions, but one developed gestational hypertension from week 27 of her pregnancy, and another developed pre-eclampsia at week 31. Both patients’ conditions were stable during pregnancy. The nine women in the study had typical symptoms of COVID-19 infection, and were given oxygen support and antibiotics. Six of the women were also given antiviral therapy. In the study, the medical records of nine pregnant women who had pneumonia caused by COVID-19 infection were retrospectively reviewed. Infection was lab-confirmed for all women in the study, and the authors studied the nine women’s symptoms.

(A) Patient 1: left-sided patchy consolidation and multiple bilateral ground-glass opacities. (B) Patient 2: subpleural patchy consolidation in the right lung and slightly infiltrated shadows around left bronchus. (C) Patient 3: bilateral multiple ground-glass opacities, prominent on the left. (D) Patient 4: left-sided patchy ground-glass opacity. (E) Patient 5: multiple ground-glass opacities bilaterally. (F) Patient 6: bilateral clear lung fields with no obvious ground-glass opacities. (G) Patient 7: right-sided subpleural patchy consolidation. (H) Patient 8: multiple bilateral ground-glass opacities, prominent on the right. (I) Patient 9: multiple bilateral ground-glass opacities.


In addition, samples of amniotic fluid, cord blood, neonatal throat swabs and breast milk were taken for six of the nine cases [2] and tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Importantly, the samples of amniotic fluid, cord blood, and neonatal throat swabs were collected in the operating room at the time of birth to guarantee that samples were not contaminated and best represented intrauterine conditions. All nine pregnancies resulted in live births, and there were no cases of neonatal asphyxia. Four women had pregnancy complications (two had fetal distress and two had premature rupture of membrane), and four women had preterm labor which was not related to their infection and occurred after 36 gestational weeks. Two of the prematurely born newborns had a low birth weight.

The authors note that their findings are similar to observations of the severe acute respiratory syndrome (SARS) virus in pregnant women, where there was no evidence of the virus being passed from mother to child during pregnancy or birth. The findings are based on a limited number of cases, over a short period of time, and the effects of mothers being infected with the virus during the first or second trimester of pregnancy and the subsequent outcomes for their offspring are still unclear, as well as whether the virus can be passed from mother to child during vaginal birth.

Dr Jie Qiao (who was not involved in the study) of Peking University Third Hospital, China,compares the effects of the virus to those of SARS, and says: “Previous studies have shown that SARS during pregnancy is associated with a high incidence of adverse maternal and neonatal complications, such as spontaneous miscarriage, preterm delivery, intrauterine growth restriction, application of endotracheal intubation, admission to the intensive care unit, renal failure, and disseminated intravascular coagulopathy. However, pregnant women with COVID-19 infection in the present study had fewer adverse maternal and neonatal complications and outcomes than would be anticipated for those with SARS-CoV-1 infection. Although a small number of cases was analysed and the findings should be interpreted with caution, the findings are mostly consistent with the clinical analysis done by Zhu and colleagues of ten neonates born to mothers with COVID-19 pneumonia."

sb admin Wed, 02/12/2020 - 13:03
Categories




cor

The Biology Of Why Coronavirus Is So Deadly

The Biology Of Why Coronavirus Is So Deadly

COVID-19 is caused by a coronavirus called SARS-CoV-2. Coronaviruses belong to a group of viruses that infect animals, from peacocks to whales. They’re named for the bulb-tipped spikes that project from the virus’s surface and give the appearance of a corona surrounding it.

A coronavirus infection usually plays out one of two ways: as an infection in the lungs that includes some cases of what people would call the common cold, or as an infection in the gut that causes diarrhea. COVID-19 starts out in the lungs like the common cold coronaviruses, but then causes havoc with the immune system that can lead to long-term lung damage or death.

SARS-CoV-2 is genetically very similar to other human respiratory coronaviruses, including SARS-CoV and MERS-CoV. However, the subtle genetic differences translate to significant differences in how readily a coronavirus infects people and how it makes them sick.

 

SARS-CoV-2 virus particles (pink dots) on a dying cell. National Institute of Allergy and Infectious Diseases, NIH

 

SARS-CoV-2 has all the same genetic equipment as the original SARS-CoV, which caused a global outbreak in 2003, but with around 6,000 mutations sprinkled around in the usual places where coronaviruses change. Think whole milk versus skim milk.

Compared to other human coronaviruses like MERS-CoV, which emerged in the Middle East in 2012, the new virus has customized versions of the same general equipment for invading cells and copying itself. However, SARS-CoV-2 has a totally different set of genes called accessories, which give this new virus a little advantage in specific situations. For example, MERS has a particular protein that shuts down a cell’s ability to sound the alarm about a viral intruder. SARS-CoV-2 has an unrelated gene with an as-yet unknown function in that position in its genome. Think cow milk versus almond milk.

 

How the virus infects

 

Every coronavirus infection starts with a virus particle, a spherical shell that protects a single long string of genetic material and inserts it into a human cell. The genetic material instructs the cell to make around 30 different parts of the virus, allowing the virus to reproduce. The cells that SARS-CoV-2 prefers to infect have a protein called ACE2 on the outside that is important for regulating blood pressure.

The infection begins when the long spike proteins that protrude from the virus particle latch on to the cell’s ACE2 protein. From that point, the spike transforms, unfolding and refolding itself using coiled spring-like parts that start out buried at the core of the spike. The reconfigured spike hooks into the cell and crashes the virus particle and cell together. This forms a channel where the string of viral genetic material can snake its way into the unsuspecting cell.

An illustration of the SARS-CoV-2 spike protein shown from the side (left) and top. The protein latches onto human lung cells. 5-HT2AR/Wikimedia

SARS-CoV-2 spreads from person to person by close contact. The Shincheonji Church outbreak in South Korea in February provides a good demonstration of how and how quickly SARS-CoV-2 spreads. It seems one or two people with the virus sat face to face very close to uninfected people for several minutes at a time in a crowded room. Within two weeks, several thousand people in the country were infected, and more than half of the infections at that point were attributable to the church. The outbreak got to a fast start because public health authorities were unaware of the potential outbreak and were not testing widely at that stage. Since then, authorities have worked hard and the number of new cases in South Korea has been falling steadily.

 

How the virus makes people sick

 

SARS-CoV-2 grows in type II lung cells, which secrete a soap-like substance that helps air slip deep into the lungs, and in cells lining the throat. As with SARS, most of the damage in COVID-19, the illness caused by the new coronavirus, is caused by the immune system carrying out a scorched earth defense to stop the virus from spreading. Millions of cells from the immune system invade the infected lung tissue and cause massive amounts of damage in the process of cleaning out the virus and any infected cells.

Each COVID-19 lesion ranges from the size of a grape to the size of a grapefruit. The challenge for health care workers treating patients is to support the body and keep the blood oxygenated while the lung is repairing itself.

 

How SARS-CoV-2 infects, sickens and kills people

 

SARS-CoV-2 has a sliding scale of severity. Patients under age 10 seem to clear the virus easily, most people under 40 seem to bounce back quickly, but older people suffer from increasingly severe COVID-19. The ACE2 protein that SARS-CoV-2 uses as a door to enter cells is also important for regulating blood pressure, and it does not do its job when the virus gets there first. This is one reason COVID-19 is more severe in people with high blood pressure.

SARS-CoV-2 is more severe than seasonal influenza in part because it has many more ways to stop cells from calling out to the immune system for help. For example, one way that cells try to respond to infection is by making interferon, the alarm signaling protein. SARS-CoV-2 blocks this by a combination of camouflage, snipping off protein markers from the cell that serve as distress beacons and finally shredding any anti-viral instructions that the cell makes before they can be used. As a result, COVID-19 can fester for a month, causing a little damage each day, while most people get over a case of the flu in less than a week.

At present, the transmission rate of SARS-CoV-2 is a little higher than that of the pandemic 2009 H1N1 influenza virus, but SARS-CoV-2 is at least 10 times as deadly. From the data that is available now, COVID-19 seems a lot like severe acute respiratory syndrome (SARS), though it’s less likely than SARS to be severe.

 

What isn’t known

 

There are still many mysteries about this virus and coronaviruses in general – the nuances of how they cause disease, the way they interact with proteins inside the cell, the structure of the proteins that form new viruses and how some of the basic virus-copying machinery works.

Another unknown is how COVID-19 will respond to changes in the seasons. The flu tends to follow cold weather, both in the northern and southern hemispheres. Some other human coronaviruses spread at a low level year-round, but then seem to peak in the spring. But nobody really knows for sure why these viruses vary with the seasons.

What is amazing so far in this outbreak is all the good science that has come out so quickly. The research community learned about structures of the virus spike protein and the ACE2 protein with part of the spike protein attached just a little over a month after the genetic sequence became available. I spent my first 20 or so years working on coronaviruses without the benefit of either. This bodes well for better understanding, preventing and treating COVID-19.

By Benjamin Neuman, Professor of Biology, Texas A&M University-Texarkana. This article is republished from The Conversation under a Creative Commons license. Read the original article.

The Conversation Thu, 04/02/2020 - 14:02
Categories




cor

Newsom extends free healthcare to 700,000 illegal immigrants despite record budget deficit

California became the first state on Monday to offer comprehensive health insurance to all undocumented immigrants, a plan expected to expand to roughly 700,000 residents living in the Golden State.




cor

Glenn Youngkin’s popularity at record high, approval throughout Virginia

Virginia Gov. Glenn Youngkin’s popularity continues to soar, even after voters turned the commonwealth’s general assembly over to Democrats.




cor

Aging, overworked and underfunded: NASA faces a dire future, according to experts

Aging infrastructure, short-term thinking and ambitions that far exceed its funding are among the problems facing NASA, according to a new report.




cor

Kids are sucking down baby food pouches at record rates. 'We're going to pay for it,' experts say

It's hard to beat the convenience of baby food pouches. But overreliance can affect a child's nutrition, food preferences and speech development, experts warn.




cor

This is what's missing in our sex lives in 2024, according to Esther Perel

In "Mating in Captivity" and "The State of Affairs," Esther Perel dissects our hidden desires and impulses with intellectual rigor.




cor

AI startup funding hit a record in the L.A. area last quarter. Here's who got the most money

L.A.-area startups received $1.8 billion in the third quarter, the highest quarterly amount for the region, according to CB Insights. Most of it went to a single company.




cor

Corporate Donors Have Abandoned Council Member Tanya Woo

Progressive newcomer Alexis Mercedes Rinck absolutely bodied Council appointee Tanya Woo in the August primary, scoring a cool 50.2% to Woo’s 38.4%. Rinck has every reason to measure drapes for the new office in City Hall she will probably move into, and it looks like the deep-pocketed outside spenders who got Woo’s buddies elected last year are counting her out too. Proportionally, Woo’s Independent Expenditure (IE) has spent 90% less this year than a similar IE did in her initial council bid. by Hannah Krieg

Progressive newcomer Alexis Mercedes Rinck absolutely bodied Council appointee Tanya Woo in the August primary, scoring a cool 50.2% to Woo’s 38.4%. Rinck has every reason to measure drapes for the new office in City Hall she will probably move into, and it looks like the deep-pocketed outside spenders who got Woo’s buddies elected last year are counting her out too. Proportionally, Woo’s Independent Expenditure (IE) has spent 90% less this year than a similar IE did in her initial council bid. 

Woo’s campaign has raised $453,000 from 7895 donors, averaging approximately $57 per contributor, according to the Seattle Ethics and Elections Commission. Her contributors include the real estate industry, CEOs, lawyers, retirees, and some of the conservative council colleagues who appointed her such as Council Members Bob Kettle and Maritza Rivera.

But typically, big IEs spend an ungodly amount of money in the last few weeks of a race on mailers, TV ads, and other strategies to get their preferred candidate's name and face in front of voters before the election. Last year, IEs backed by business or labor or both spent $1.6 million across the seven City Council elections. The candidate with the most outside spending through IEs won in every race besides Woo's failed bid for District Two. Between her campaign and IEs, she outspent her opponent, incumbent Tammy Morales, two to one. 

But IEs don’t seem as interested in burying progressive competition with their cash this time around. 

Many of the same donors who backed Woo in 2023, funded the victorious conservative slate that appointed her, and the previous three mayors. They collectively contributed more than $130,000 to Woo through the Friends of Seattle. This includes the Commercial Real Estate Development Association, Seattle Hospitality for Progress PAC, R.C. Hedreen Company, Goodman Real Estate, and HomeStreet Bank. 

But they don’t seem to be trying as hard this go round. 

A 2023 IE, Friends of SE Seattle, spent $168,000 on her bid for the District 2 seat where she had to win over a majority of the 67,000 registered voters. That’s an investment of $2.50 a voter. Now, in 2024, for her citywide campaign, she’s trying to capture the majority of 485,000 voters. A $130,000 investment from the current IE shakes out to about a quarter spent per voter. That means IEs, who successfully bought every seat besides Woo’s last cycle, have spent 90% less on Woo than they did in her last election where she lost despite spending twice as much as her opponent.

This marks a shift in behavior from corporate donors when compared to the last time Seattle voted on citywide council seats in 2021. An IE called Change Seattle pooled $414,000 for Council President Sara Nelson’s bid for a citywide seat or about three times as much as they are spending on Woo. 

What does any of this mean? Well, it could mean those conservative donors are stretched thin funding the awful, Republican-backed Let’s Go Washington Initiatives, the Republican candidate for governor, or maybe even President Donald Trump’s third shot at the White House. Or, it could mean these corporate donors are saving up to support their darlings, Nelson, City Attorney Ann Davison, and Mayor Bruce Harrell, when they go up for re-election next year. 

Either way, progressives aren’t really beating conservatives at the fundraising game. Rinck's campaign has raised $460,790 from 8,637 contributors, averaging slightly more than $53 per contributor Her contributors include unions, labor organizers, every progressive politico you can think of, and politicians including King County Executive Dow Constantine, Woo’s old foe Morales, and many state lawmakers representing Seattle.

Rinck also found support in a new IE, Progressive People Power (P3), that spent more than $190,000 this cycle. P3’s donors include SEIU 775, which made up more than half of the pot, some other unions, several failed left-lane candidates, and King County Democrats Chair Carrie Barnes who gave more than $42,000 herself. Didn’t know you had it like that, Barnes!

But as P3 Board Chair Ry Armstrong said at a fundraiser last month, progressives don’t need as much money to win — their ideas are just better. A recent poll by the Northwest Progressive Institute found only 28% of respondents voted or will vote for Woo, while 52% voted or will vote for Rinck.

Worried about Tuesday? Here's something to look forward to via @nwprogressive! pic.twitter.com/LQrEh7GSfV

— Hannah Krieg (@hannahkrieg) November 3, 2024

 




cor

Correct These 5 Common SEO Mistakes To Boost Your Traffic

Undoubtedly WordPress has been excellently set up to get the best of Search Engine Optimization. That’s the reason why most of us are always reluctant to get away from the cozy comfort of WordPress and get the site hosted with third party. Also, transition to a third party means increased responsibility starting from the need […]




cor

Sarah Borghi Trendy 40 Corpino 40~70d.

Sarah Borghi women satin sheer support tights. Lycra with leg in 40 denier and graduated compression support modelling to panty in 70 den. Medium support. Cotton gusset and panel gusset. Flat seams. Fully boarded. Sanitized to ensure long-term protection against unpleasant odours. Meryl labelled. A 'milder' version of medical panthose. Made in Italy. Colors Playa,Chiaro,Sabbia,Cappuccio,Fume`,Moka,Nero,Glace`. Sizes 1,2,3,4,5. See Sizechart. Price: USD11.24




cor

Incorporate the Interbanks Funds Transfer

Incorporate the Interbanks Funds Transfer as another means of secured payment for online purchases made on www.newlook.com.sg.




cor

Incorporated Google translation in 5 European languages

Besides supporting English, Newlook Marketing has added Google translation in 5 European languages: French, German, Italian, Portuguese and Spanish. To translate to any of these language, click on the link found at the footer of every webpage.




cor

New collection: Embroidered corset with G-String

A new collection of Corset by Sensual Mystique®.

Embroidered corset with push-up underwire cups. With front lace-up, hook and eye back. With detachable adjustable garter and matching g-string.




cor

New collection: Chinese Jacquard Strapless Corset with G-String

A new collection of Corset by Sensual Mystique®.

Beautiful chinese jacquard, strapless corset with lace-up back, slimming waist and detachable garters. Comes with a matching g-string. Designs from USA.




cor

New collection: Slimming Jacquard Strapless Corset with Thong

A new collection of Corset by Sensual Mystique®.

Slimming jacquard tapestry, strapless corset. Comes with matching thong panty, gorgeous venice trim, hook and eye front, waist cinching lace-up back as well as removable, adjustable garters. Designs from USA.




cor

New collection: Satin Corset with matching G-String

A new collection of cami by Sensual Mystique®.

Satin shine corset with boning and matching g-string. Side zip with ribbon lace up front.




cor

New collection: Lycra corchet stockings

A new collection of thigh hi stockings by Elegant Moments®.

Sensual corchet thigh hi with Lycra.

Onesize: 90 to 160 lbs, 41 to 73 Kg




cor

New collection: Lycra corchet stockings Queensize

A new collection of corchet thigh hi stockings by Elegant Moments®.

Sensual corchet thigh hi with Lycra.

Queensize: 1x - 3x