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Class and campus life [electronic resource] : managing and experiencing inequality at an elite college / Elizabeth M. Lee

Lee, Elizabeth M., 1974- author




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Debating Durkheim [electronic resource] / edited by W.S.F. Pickering and H. Martins




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The fractal organization [electronic resource] : creating enterprises of tomorrow / Pravir Malik

Malik, Pravir




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Frühe Hilfen [electronic resource] : die Bedeutung primärpräventiver Unterstützungsangebote für Schwangere, Mütter und Familien durch Kooperation von Sozialarbeit und Gesundheitswesen / Gerda Schwarz

Schwarz, Gerda




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Gender, Masculinity and Video Gaming [electronic resource] : Analysing Reddit's r/gaming Community / by Marcus Maloney, Steven Roberts, Timothy Graham

Maloney, Marcus. author




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Going horizontal [electronic resource] : creating non-hierarchical organizations, one practice at a time / Samantha Slade

Slade, Samantha, author




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The host in the machine [electronic resource] : examining the digital in the social / Angela Thomas-Jones

Thomas-Jones, Angela




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Investment in Early Childhood Education in a Globalized World [electronic resource] : Policies, Practices, and Parental Philosophies in China, India, and the United States / by Guangyu Tan, Amita Gupta, Gay Wilgus

Tan, Guangyu. author




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Living with climate change [electronic resource] : how communities are surviving and thriving in a changing climate / Jane A. Bullock, George D. Haddow, Kim S. Haddow, Damon P. Coppola

Bullock, Jane A., author




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Nordic-Chinese Intersections within Education [electronic resource] / edited by Haiqin Liu, Fred Dervin, Xiangyun Du




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Organizational development and alignment [electronic resource] : the Tensegrity mandala framework / Gagandeep Singh, Raghu Ananthanarayanan




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Psychische Gewalt in der Erziehung [electronic resource] : Erkennungsproblematik und Erkennungschancen für die soziale Arbeit / Lilli Mertes

Mertes, Lilli




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Sociological probings in rural society [electronic resource] / edited by K.L. Sharma




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Talking about Leaving Revisited [electronic resource] : Persistence, Relocation, and Loss in Undergraduate STEM Education / edited by Elaine Seymour, Anne-Barrie Hunter




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Transforming research libraries for the global knowledge society [electronic resource] / edited by Barbara I. Dewey




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We can't talk about that at work! [electronic resource] : how to talk about race, religion, politics, and other polarizing topics / Mary-Frances Winters

Winters, Mary-Frances, author




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Understanding street culture : poverty, crime, youth and cool / Jonathan Ilan

Ilan, Jonathan




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Variable protein expression in marine-derived filamentous fungus Penicillium chrysogenum in response to varying copper concentrations and salinity

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00316A, Paper
Nikita Lotlikar, Samir Damare, Ram Murti Meena, Saranya Jayachandran
Copper is one of the essential trace dietary minerals for all living organisms, but is potentially toxic at higher concentrations, mainly due to the redox reactions in its transition state.
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Defining the mechanism of the mitochondrial Atm1p [2Fe–2S] cluster exporter

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00286C, Paper
Stephen A. Pearson, Christine Wachnowsky, J. A. Cowan
Atm1p mediated mitochondrial Fe–S cluster export is investigated, providing support for a [2Fe–2S](GS)4 cluster as a physiological substrate. A detailed mechanism of cluster export, combining kinetic, thermodynamic, and structural data is presented.
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The first copper(II) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00006J, Paper
Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta
The novel complex Cu(phen)2(salubrinal)(ClO4)2 shows high free radical scavenging activity and good cytotoxic activity and induces cell death through ER-stress.
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Studies of the labile lead pool using a rhodamine-based fluorescent probe

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00056F, Communication
Jianping Zhu, Jia Hao Yeo, Amy A. Bowyer, Nicholas Proschogo, Elizabeth J. New
A rhodamine-based fluorescent lead probe reports on the labile lead pool within cells.
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Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00084A, Paper
Sabiha Parveen, J. A. Cowan, Zhen Yu, Farukh Arjmand
Copper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission–fusion disorder and excessive mitophagy in hippocampal nerve cells of rats

Metallomics, 2020, 12,592-606
DOI: 10.1039/C9MT00291J, Paper
Miao Yu, Jinghua Yang, Xiang Gao, Wenchang Sun, Shiyu Liu, Yarao Han, Xiaobo Lu, Cuihong Jin, Shengwen Wu, Yuan Cai
Lanthanum chloride damages hippocampal nerve cells of rats through inducing [Ca2+]m overload, mitochondrial fission–fusion disorder, and excessive mitophagy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Heterobimetallic Ru(II)/Fe(II) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets

Metallomics, 2020, 12,547-561
DOI: 10.1039/C9MT00272C, Paper
Adriana Pereira Mundim Guedes, Francyelli Mello-Andrade, Wanessa Carvalho Pires, Maria Alice Montes de Sousa, Paula Francinete Faustino da Silva, Mariana S. de Camargo, Hendryk Gemeiner, Menegário A. Amauri, Clever Gomes Cardoso, Paulo Roberto de Melo Reis, Elisângela de Paula Silveira-Lacerda, Alzir A. Batista
Antimetastatic activity, high selectivity and cytotoxicity for human tumor cell lines make ruthenium(II) complexes attractive for the development of new chemotherapeutic agents for cancer treatment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques

Metallomics, 2020, 12,539-546
DOI: 10.1039/C9MT00306A, Paper
Xiayoue Zhu, Tiffany W. Victor, Ashwin Ambi, Joseph K. Sullivan, Joshua Hatfield, Feng Xu, Lisa M. Miller, William E. Van Nostrand
Multimodal imaging studies show that Aβ amyloid in brain vessels of Tg2576 mice (green) preferentially binds copper (red) – a pathology that can be reduced with copper chelators.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Selenium deficiency exacerbates LPS-induced necroptosis by regulating miR-16-5p targeting PI3K in chicken tracheal tissue

Metallomics, 2020, 12,562-571
DOI: 10.1039/C9MT00302A, Paper
Lanqiao Wang, Xu Shi, Shufang Zheng, Shiwen Xu
Se deficiency can induce necroptosis in tracheal tissue. LPS-induced necroptosis can be exacerbated by Se deficiency. The miR-16-5p-PI3K/AKT pathway participates in the occurrence of necroptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hierarchical binding of copperII to N-truncated Aβ4–16 peptide

Metallomics, 2020, 12,470-473
DOI: 10.1039/C9MT00299E, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xiangyu Teng, Ewelina Stefaniak, Paul Girvan, Radosław Kotuniak, Dawid Płonka, Wojciech Bal, Liming Ying
Multiple intermediates were found in Cu(II) binding to Aβ4–16 before the formation of a tight complex.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ruthenium(III) complexes containing thiazole-based ligands that modulate amyloid-β aggregation

Metallomics, 2020, 12,491-503
DOI: 10.1039/D0MT00054J, Paper
Samantha E. Huffman, Gideon K. Yawson, Samuel S. Fisher, Paige J. Bothwell, David C. Platt, Marjorie A. Jones, Christopher G. Hamaker, Michael I. Webb
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Peptide bond cleavage in the presence of Ni-containing particles

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00070A, Communication
Nina Ewa Wezynfeld, Tomasz Frączyk, Arkadiusz Bonna, Wojciech Bal
NiO nanoparticles and non-stoichiometric black NiO were shown to be effective sources of Ni2+ ions causing sequence-selective peptide bond hydrolysis. NiO nanoparticles were as effective in this reaction as their...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00074D, Paper
Fabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. Soares
Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A liver-targeting Cu(I) chelator relocates Cu in hepatocytes and promotes Cu excretion in a murine model of Wilson’s disease

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00069H, Paper
Marie Monestier, AnaÏS M. Pujol, Aline Lamboux, Martine Cuillel, Isabelle Pignot-Paintrand, Doris Cassio, Peggy Charbonnier, Khémary Um, Amélie Harel, Sylvain BOHIC, Christelle GATEAU, Vincent Balter, Virginie Brun, Pascale Delangle, Elisabeth Mintz
Copper chelation is the most commonly used therapeutic strategy nowadays to treat Wilson’s disease, a genetic disorder primarily inducing a pathological accumulation of Cu in the liver. The mechanism of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00051E, Paper
Federica Violi, Nikolay Solovyev, Marco Vinceti, Jessica Mandrioli, Marianna Lucio, Bernhard Michalke
Gene-environment interaction is as a possible key factor in the development of ALS. The levels of redox species of Cu, Fe, and Mn were assessed in cerebrospinal fluid, showing a possible positive association between Cu and genetic ALS.
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Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00076K, Paper
Xinyang Li, Chao Zuo, Mei Wu, Zunzhen Zhang
Linc-ROR modulates the cell proliferation in arsenite-transformed keratinocytes via inhibiting P53 activity through the PI3K/AKT pathway.
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Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00048E, Paper
Melissa Scholefield, Stephanie J. Church, Jingshu Xu, Sarah Kassab, Natalie J. Gardiner, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. Cooper
Metal findings in human Alzheimer brains are consistent despite differences in sample post-mortem delay, age, Braak stage and biobank location.
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History and Imperialism: Writings, 1963-1986


 
Writings on History brings together a selection of texts by Louis Althusser dating from 1963 to 1986, including essays, a lecture, notes to his collaborators, and the transcript of an informal 1963 discussion of literary history. The centrepiece of this collection is Althusser’s previously unpublished Book on Imperialism, a theorization of globalized capitalism that remained unfinished.  All these writings are concerned with the place of history in

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History and Imperialism: Writings, 1963-1986


 
Writings on History brings together a selection of texts by Louis Althusser dating from 1963 to 1986, including essays, a lecture, notes to his collaborators, and the transcript of an informal 1963 discussion of literary history. The centrepiece of this collection is Althusser’s previously unpublished Book on Imperialism, a theorization of globalized capitalism that remained unfinished.  All these writings are concerned with the place of history in

Read More...




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Reacher Said Nothing: Lee Child and the Making of Make Me


 
It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end.
 
On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped

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Reacher Said Nothing: Lee Child and the Making of Make Me


 
It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end.
 
On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped

Read More...




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Critical Essays on Elmore Leonard: If It Sounds Like Writing


 

A scholarly exploration of Elmore Leonard—provides original essays and fresh insights on the author’s works and influence

Labelled as “the closest thing America has to a national novelist,” Elmore Leonard’s clean and direct writing, engaging bad guys, and deadpan humor resonate with readers around the nation and throughout the world. Popular films based on his books continue to introduce new audiences to Leonard’s unique way of engaging with complex



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Held for spiking fuel

Held for spiking fuel




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Lifting of PDS rice for the month of May begins

Lifting of PDS rice for the month of May begins




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TSE proprietor extends helping hand to widows, differently abled persons

TSE proprietor extends helping hand to widows, differently abled persons




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Kangpokpi asks passenger vehicles not to stop midway

Kangpokpi asks passenger vehicles not to stop midway




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[ASAP] In Vitro Identification of the Hamiltonian Cycle Using a Circular Structure Assisted DNA Computer

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00150




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[ASAP] Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00001




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[ASAP] Optimized Multimetal Sensitized Phosphor for Enhanced Red Up-Conversion Luminescence by Machine Learning

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00035




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[ASAP] Magnetic Bead-Immobilized Mammalian Cells Are Effective Targets to Enrich Ligand-Displaying Yeast

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00036




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[ASAP] Experimental and Theoretical Investigation on Phase Formation and Mechanical Properties in Cr–Co–Ni Alloys Processed Using a Novel Thin-Film Quenching Technique

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00170




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NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism

Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.




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Testing with combined biopsy method improves prostate cancer diagnosis in NCI study

Testing for prostate cancer with a combined biopsy method led to more accurate diagnosis and prediction of the course of the disease in an NCI study. The method is poised to reduce the risk of prostate cancer overtreatment and undertreatment.