small #buyfromthebush calls on city consumers to keep small-town shops open during drought By www.abc.net.au Published On :: Thu, 24 Oct 2019 06:26:00 +1100 A social media campaign quickly gathers followers as it shines a light on drought-affected towns struggling to maintain their businesses, and encourages people to buy remotely in the lead-up to Christmas. Full Article ABC Radio Sydney westernplains sydney riverina Business Economics and Finance:Small Business:All Disasters and Accidents:Drought:All Human Interest:People:All Information and Communication:Internet:Social Media Rural:All:All Weather:All:All Australia:NSW:Coonamble 2829 Australia:NSW:Dubbo 2830 Australia:NSW:Sydney 2000 Australia:NSW:Wagga Wagga 2650 Australia:NSW:Walgett 2832 Australia:NSW:Warren 2824
small ‘My Boy Lollipop’ Singer Millie Small Passes Away At 72 By feeds.bet.com Published On :: Wed, 6 May 2020 20:30:00 EDT The Jamaican national reportedly suffered a stroke. Full Article Music News
small The Lancet Rheumatology: Small observational study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements By www.eurekalert.org Published On :: Thu, 07 May 2020 00:00:00 EDT The first study to report use of the rheumatoid arthritis drug anakinra to treat COVID-19 patients found that high-dose anakinra was safe and was associated with respiratory improvements and reduced signs of cytokine storm [1] in 72% (21/29) of patients, according to results from patients studied for 21 days (enrolled from 17 to 27 March 2020) in a Milan hospital, published in The Lancet Rheumatology journal. Full Article
small Could smaller nuclear reactors be a possible energy source for Queensland? By www.abc.net.au Published On :: Wed, 22 Apr 2020 06:21:23 +1000 The debate over nuclear technology is a controversial one, yet many leaders in the field believe it's time for an open and calm discussion about the energy alternative. Full Article Nuclear Energy Electricity Energy and Utilities Solar Energy Federal Parliament
small Why this former US Congress hopeful is betting on a small country newspaper By www.abc.net.au Published On :: Sun, 03 May 2020 05:30:02 +1000 Michael Waite ran for office in Washington and worked for Bill Gates' private investment company, but helping establish a community newspaper could be his toughest challenge yet. Full Article Information and Communication Print Media Rural Rural Media Small Business Business Economics and Finance Media US Elections
small Coronavirus lockdown changes will be 'modest' and 'small' By news.sky.com Published On :: Thu, 07 May 2020 15:12:00 +0100 The public have been told not to expect widespread changes to the coronavirus lockdown in England when Boris Johnson addresses the nation this weekend. Full Article
small 'It's too soon': In small towns and big cities, Georgia's experiment in reopening moves slowly By www.latimes.com Published On :: Fri, 1 May 2020 20:48:50 -0400 A week after Georgia Gov. Brian Kemp plunged Georgia into the middle of a national social experiment — rolling back restrictions on businesses in an effort to restart the economy after a monthlong shutdown to halt the spread of COVID-19 — some restaurants, salons and tattoo parlors remain shuttered. Most that are opening are proceeding cautiously. Full Article
small Phase 3 Libtayo monotherapy trial halted early due to strong benefit in advanced non-small cell lung cancer By www.pharmafile.com Published On :: Wed, 29 Apr 2020 11:49:31 +0000 A Phase 3 study of Sanofi and Regeneron’s Libtayo (cemiplimab) as a monotherapy for advanced or metastatic non-small cell lung cancer (NSCLC) has been stopped early after showing strong overall survival benefit, it has emerged. Full Article cancer Libtayo lung cancer Regeneron Research and Development Sanofi
small FDA approval for Tabrecta in metastatic non-small cell lung cancer with METex14 By www.pharmafile.com Published On :: Thu, 07 May 2020 11:35:49 +0000 The FDA has awarded marketing authorisation to Novartis for the Oral MET inhibitor Tabrecta for the first-line treatment of metastatic non-small cell lung cancer in patients whose tumors have a mutation that leads to MET exon 14 skipping (METex14), regardless of whether they have previously received any type of treatment. Full Article Incyte Novartis pharma Tabrecta Sales and Marketing
small Justice Department Reaches Settlement with SmallTownPapers Inc., Regarding Employment Rights of Air Force Reservist By www.justice.gov Published On :: Wed, 11 Feb 2009 13:08:53 EST The Department has reached a settlement that, if approved by the court, will resolve a lawsuit the Department filed on behalf of Air Force Reservist Frank Bonnin against SmallTownPapers Inc., (SmallTownPapers). The complaint, filed in August 2008 in U.S. District Court in Seattle, alleged that SmallTownPapers violated the Uniformed Services Employment and Reemployment Rights Act of 1994 (USERRA) when it terminated Bonnin from his position as director of publisher relations due to his military obligation as an Air Force Reservist to attend active duty training. Full Article OPA Press Releases
small Georgia Temp Company and Its Owner/President Agree to Plead Guilty to Making a False Statement to the U.S. Small Business Administration By www.justice.gov Published On :: Fri, 17 Jul 2009 17:51:43 EDT A Georgia temporary staffing company and its owner/president have agreed to plead guilty to making a false statement to the U.S. Small Business Administration (SBA). Patriot Services Inc. and its owner/president, Stephanie Blackmon, have each agreed to plead guilty to a one-count charge of making a false statement to the SBA, which was filed today in U.S. District Court in Kansas City, Kan. Full Article OPA Press Releases
small New York Small Business Lender to Pay U.S. $26.3 Million to Resolve False Claims Act Allegations By www.justice.gov Published On :: Thu, 6 May 2010 10:18:41 EDT Ciena Capital LLC, a private, non-depository lender located in New York City, has reached an agreement with the United States to settle fraud claims related to its small business lending for $26.3 million. Full Article OPA Press Releases
small United States Files Counterclaims and Crossclaims in Small Business Administration Loan Fraud Case By www.justice.gov Published On :: Tue, 15 Jun 2010 14:06:07 EDT The United States filed False Claims Act counterclaims against Saehan Bank and crossclaims against Steve Yong Kim and Young Soon Kim in the Northern District of Oklahoma. Full Article OPA Press Releases
small Bank to Pay $2.2 Million to Settle Allegations of False Claims to Small Business Administration By www.justice.gov Published On :: Thu, 7 Oct 2010 17:41:45 EDT Saehan Bank has agreed to pay the United States $2.2 million to settle allegations arising under the False Claims Act and the Financial Institutions Reform, Recovery and Enforcement Act with respect to a Small Business Administration (SBA) loan, the Justice Department announced. Full Article OPA Press Releases
small Lender to Pay $300,000 to Settle Allegations Involving Small Business Administration Loan By www.justice.gov Published On :: Mon, 23 May 2011 11:49:49 EDT Garsh Lending LLC, a lender located in Miami, has agreed to pay the United States $300,000 to settle allegations involving a Small Business Administration loan. Full Article OPA Press Releases
small NASA Contractor to Pay U.S. to Resolve False Claims Act Liability Concerning Service-Disabled Veteran-Owned Small Business Fraud By www.justice.gov Published On :: Wed, 21 Sep 2011 14:55:43 EDT Lydia Demski, the owner of Deerpath Corp., has agreed to pay the United States $800,000 to resolve allegations that she and her companies knowingly caused false claims to be submitted relating to a contract to provide re-furbishment of equipment at the National Aeronautics and Space Administration’s (NASA) Plumbrook facility in Sandusky, Ohio. Full Article OPA Press Releases
small Deputy Attorney General James M. Cole Speaks at the Office of Small and Disadvantaged Business Utilization Small Business Procurement Conference By www.justice.gov Published On :: Thu, 19 Apr 2012 09:27:34 EDT "At the Department of Justice, we know that small businesses are adaptable and innovative. We have come to rely on them to support many of our most important missions, from ensuring the national security to combating violent crime, fighting financial fraud, and protecting those most in need of our help – our children; the elderly; and victims of hate crimes, human trafficking and exploitation," said Deputy Attorney General Cole. Full Article Speech
small Kentucky-Based Defense Contractors, Owners Agree to Pay $6.25 Million to Resolve Allegations That They Submitted False Statements and Claims to Obtain Army Contracts Intended for Small Businesses By www.justice.gov Published On :: Wed, 5 Dec 2012 14:59:08 EST Kentucky-based Lusk Mechanical Contractors and Commonwealth Technologies, and their owners, Harry Lusk and Wendell Goodman, have agreed to pay $6.25 million to resolve allegations that they submitted false statements to the Small Business Administration and false claims to the Army, the Justice Department announced today. Full Article OPA Press Releases
small Security Contractors Plead Guilty in Virginia to Illegally Obtaining $31 Million from Contracts Intended for Disadvantaged Small Businesses By www.justice.gov Published On :: Mon, 18 Mar 2013 15:22:47 EDT Executives at two Arlington, Va.-based businesses have pleaded guilty to fraudulently obtaining more than $31 million in government contract payments that should have gone to disadvantaged small businesses. Full Article OPA Press Releases
small Former Security Contractor Executives Sentenced for Illegally Obtaining More Than $31 Million Intended for Disadvantaged Small Businesses By www.justice.gov Published On :: Fri, 14 Jun 2013 11:12:14 EDT Two executives at a Virginia-based security contracting firm were sentenced in the Eastern District of Virginia for their roles in using a front company to obtain more than $31 million intended for disadvantaged small businesses as part of the Small Business Administration’s (SBA) Section 8(a) program. This program allows qualified small businesses to receive sole-source and competitive-bid contracts set aside for minority-owned and disadvantaged small businesses. Full Article OPA Press Releases
small Former Security Contractor CEO Sentenced for Masterminding $31 Million Disadvantaged Small Business Fraud Scheme By www.justice.gov Published On :: Fri, 21 Jun 2013 11:54:47 EDT The former chief executive officer of a Virginia-based security contracting firm was sentenced in the Eastern District of Virginia to 72 months in prison for creating a front company to obtain more than $31 million intended for disadvantaged small businesses and for bribing the former regional director for the National Capital Region of the Federal Protective Service (FPS) as part of the scheme. Full Article OPA Press Releases
small Security Contractor Sentenced to Four Years in Prison for Role as Figurehead Owner in $31 Million Small Business Fraud Scheme By www.justice.gov Published On :: Fri, 28 Jun 2013 14:56:13 EDT The chief executive officer of a Virginia-based security contracting firm was sentenced today to serve four years in prison for serving as a figurehead owner of a front company created to obtain more than $31 million intended for disadvantaged small businesses through the Small Business Administration’s (SBA) Section 8(a) program, which allows qualified small businesses to receive sole-source and competitive-bid contracts set aside for minority-owned and disadvantaged small businesses. Full Article OPA Press Releases
small Utah Construction Company to Pay Government to Settle Alleged False Claims in Connection with Program for Small and Disadvantaged Businesses By www.justice.gov Published On :: Fri, 21 Mar 2014 16:38:05 EDT Okland Construction Co. Inc. has agreed to pay the government $928,000 to resolve allegations that it made false statements and submitted false claims under the Small Business Administration’s (SBA) Section 8(a) Program for Small and Disadvantaged Businesses. Full Article OPA Press Releases
small California-Based Masonry Companies Pay Nearly $1.9 Million to Settle Claims of Misrepresenting Disadvantaged Small Business Status in Connection with Military Contracts By www.justice.gov Published On :: Wed, 9 Apr 2014 12:01:06 EDT Five California-based masonry subcontractors and two individuals paid the government nearly $1.9 million to resolve allegations that they violated the False Claims Act by misrepresenting their disadvantaged small business status in connection with military construction contracts. Full Article OPA Press Releases
small How APEC Helps Small Business Go Global By www.apec.org Published On :: Thu, 29 Aug 2019 08:55:00 +0800 From access to capital to dispute resolution. Full Article
small Digital Transformation is Vital for Small Businesses By www.apec.org Published On :: Wed, 04 Sep 2019 11:21:00 +0800 “Ten, twenty, thirty years ago, you were in the best position to go global if you were a large company and had a lot of resources and access to a lot of attorneys and advisors who could help you navigate regulations and issues that get more complicated as you go abroad.” Full Article
small APEC Small and Medium Enterprises Ministers Issue Joint Statement By www.apec.org Published On :: Fri, 06 Sep 2019 00:10:00 +0800 Ministers in charge of small and medium enterprises (SMEs) in the APEC region issued a statement following their meeting in Concepcion, Chile, on 5-6 September 2019. Full Article
small Wanted: Data on the Gender Gap, Digital Divide and Small Businesses By www.apec.org Published On :: Fri, 06 Sep 2019 12:01:00 +0800 We need it for inclusive policymaking Full Article
small Optimizing Outsourcing Options for Small Sponsors By polarisconsultants.blogspot.com Published On :: Tue, 06 Sep 2016 12:58:00 +0000 What can small sponsors do to secure the outsourcing resources they need as large CROs form strategic alliances with Big Pharma?Partenships between large pharmaceutical companies and large CROs have become the norm. The advantages for sponsor companies include shared risk, knowledge transfer, dedicated resources, shorter time to market, and the ability to implement the massive data integration that clinical development requires. Strategic alliances are arguably as advantageous for their outsourcing partners, providing a steady pipeline of work that’s larger in scope and longer in duration than is typical under traditional arrangements. Strategic Partnerships in Big Pharma: Implications for the RestAdvantages for one segment of the industry can introduce disadvantages for another. Alliances among the large players increase competition for top-drawer CRO resources. Smaller sponsors may find it more difficult to receive the quality of service and level of commitment they might otherwise expect. A large CRO is likely to assign their most talented personnel to projects associated with their strategic partners. And if a partner study were to run into trouble, it would be hard to fault a CRO for pulling experienced staff members off a smaller project in order to help out with the big client. Though a reputable CRO wouldn’t jeopardize the relationship with the smaller client, their responsiveness to routine requests might suffer. It might take longer to get a question answered, receive requested documentation, making the job of vendor oversight difficult.Though selecting a large, well-established CRO at the outset may have seemed like the safe bet, what do you do if you’re a small sponsor or biotech start-up who is dissatisfied with the level of service you’re receiving?“Let’s Bring It In-house.”Put off by a negative experience, many companies decide to curtail outsourcing, and bring functions like monitoring and project management in-house.This response is understandable, but it rarely goes well. There’s good reason to outsource study functions to a CRO, especially if you’re small, or new, or both. Mid-study is a terrible time to realize you’re in over your head. You may find it difficult to contract with the service providers you want in the timeframe you need them. Services you would have preferred be performed by a single company may now have to be farmed out piecemeal, which has the overhead of multiple contracts and makes vendor oversight more difficult to manage. You don’t have time to go through a thorough qualification process. You’re not in a good bargaining position; you’re trying to buy a new car after they’ve towed away your old one. And now you have to rely on your new service provider(s) – the ones who may not be your first choice, whom you had to choose in haste, whom you didn’t get to thoroughly vet – to jump in midstream and pick up a study that is already in trouble.Options for Small Sponsors and Start-upsSo what’s the answer? You have several good options we’ve seen work well for smaller organizations.(1) Go smaller. Look beyond traditional outsourcing choices and consider selecting smaller vendors who may well be in a better position to focus on individual projects and give priority to shorter term engagements. After all, a project that’s small to a big CRO will be comparatively big to a small CRO.(2) Go long-term. Consider establishing strategic partnerships of your own. Doing so would increase the expertise and technology to which you’d have ready access, and could extend your global reach.(3) Go big, but go vigilantly. There’s a reason companies hire big, reputable CROs. ‘Big’ means the CRO has an impressive set of resources at its disposal. ‘Reputable’ means it has a proven record of successfully completing studies, producing reliable data, and preserving subject safety. Smaller sponsors can still take advantage of everything a big CRO offers if they can commit to conducting very strict vendor oversight. They need to closely monitor the quality of the work the CRO performs, frequently assess adherence to the many written study plans, and make sure deadlines are being met. Service contracts should guarantee a certain level of responsiveness (by specifying maximum turn-around times, for example), especially for those requests that enable these oversight activities.Qualification is KeyWhile the key to Option 3 is effective vendor management, the key to Options 1 and 2 is effective vendor qualification. Resources are tight in a small company, so you need to direct them where your exposure is greatest, where they’ll do the most good. What could be more essential to the success of your study than choosing the right company to conduct it? Many sponsors conduct on-site vendor audits. That’s good. That’s necessary. But it’s not sufficient. To consistently choose the best possible CRO for your study, sponsors need to:Formally document and maintain vendor selection criteria and qualification processForm selection committees that represent all sides of your business – finance, contracting, operations, finance, QA, data management, pharmacovigilance, biostatistics, etc.Conduct on-site audits with well-trained, well-prepared QA auditorsTrack the resulting CAPA activitiesEnsure outstanding issues are resolved before the contract is signedPeriodically re-evaluate vendors to make sure they can continue to deliver the same level of quality they’ve delivered in the pastStrategic partnerships among large companies have reshaped the research environment for industry players of every size. Small and mid-sized companies who take the time to review current outsourcing arrangements, assess alternative models, and thoroughly qualify new vendors and partners will fare the best.Photo Credit: FreeImages.com/Svilen Milev Full Article CRO sponsor strategic alliance strategic partnership vendor audits vendor qualification
small Phase 3 trial of Libtayo® (cemiplimab) as monotherapy for first-line advanced non-small cell lung cancer stopped early due to highly significant improvement in overall survival By www.news.sanofi.us Published On :: Mon, 27 Apr 2020 08:40:00 -0400 - Libtayo decreased the risk of death by 32.4% compared to chemotherapy Full Article
small None Better than One? (A Brief Note on VC in Smaller Hubs) By thenextelement.wordpress.com Published On :: Wed, 20 May 2015 00:58:24 +0000 Biotech venture funding metrics continue at historic highs, highlighting that the robust financing environment in the public markets continues to fuel the private markets as well. – Bruce Booth, partner Atlas Venture in Data Snapshot: Venture-Backed Biotech Financing Riding High, April 2015 Here in Madison, Wisconsin, you might not know that was true if youRead More Full Article Uncategorized angel investors biotech biotechnology VC venture capital Wisconsin
small Japan small business aid would cover two-thirds rent for 6 months By asia.nikkei.com Published On :: Full Article
small Early assessment of <i>KRAS</i> mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer By feeds.nature.com Published On :: 2020-05-07 Full Article
small Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
small Monogenic small vessel diseases — rare but still important By feeds.nature.com Published On :: 2020-04-30 Full Article
small 'Small encouraging signs' for Schumacher By en.espnf1.com Published On :: Wed, 12 Mar 2014 07:58:15 GMT Michael Schumacher's condition is showing "small encouraging signs" of recovery, though he remains in the wake-up phase from his medically-induced coma Full Article
small The end of grand strategy: America must think small By webfeeds.brookings.edu Published On :: Mon, 13 Apr 2020 18:46:33 +0000 Full Article
small The end of grand strategy: America must think small By webfeeds.brookings.edu Published On :: Mon, 13 Apr 2020 18:46:33 +0000 Full Article
small How the Small Businesses Investment Company Program can better support America’s advanced industries By webfeeds.brookings.edu Published On :: Wed, 26 Jun 2019 19:20:56 +0000 On June 26, Brookings Metro Senior Fellow and Policy Director Mark Muro testified to the Senate Committee on Small Business and Entrepreneurship about the need for the reauthorization of the Small Business Administration (SBA), and particularly on the Small Business Investment Company (SBIC) program, to be better positioned to further support America’s advanced industry sector.… Full Article
small The Future of Small Business Entrepreneurship: Jobs Generator for the U.S. Economy By webfeeds.brookings.edu Published On :: Fri, 04 Jun 2010 09:55:00 -0400 Policy Brief #175 As the nation strives to recover from the “Great Recession,” job creation remains one of the biggest challenges to renewed prosperity. Small businesses have been among the most powerful generators of new jobs historically, suggesting the value of a stronger focus on supporting small businesses—especially high-growth firms—and encouraging entrepreneurship. Choosing the right policies will require public and private decision-makers to establish clear goals, such as increasing employment, raising the overall return on investment, and generating innovations with broader benefits for society. Good mechanisms will also be needed for gauging their progress and ultimate success. This brief examines policy recommendations to strengthen the small business sector and provide a platform for effective programs. These recommendations draw heavily from ideas discussed at a conference held at the Brookings Institution with academic experts, successful private-sector entrepreneurs, and government policymakers, including leaders from the Small Business Administration. The gathering was intended to spur the development of creative solutions in the private and public sectors to foster lasting economic growth. RECOMMENDATIONS What incentives and assistance could be made available to “gazelles” and to small business more generally? What policies are likely to work most effectively? In the near term, government policies aimed at bolstering the recovery and further strengthening the financial system will help small businesses that have been hard hit by the economic downturn. Spurred by the interchange of ideas at a Brookings forum on small businesses, we have identified the following more targeted ideas for fostering the health and growth of small businesses (and, in many cases, larger businesses) over the longer run: Improve access to public and private capital. Reexamine corporate tax policy with an eye toward whether provisions of our tax code are discouraging small business development. Promote education to help businesses struggling with shortages of workers with particular skills, and promote research to spur innovation. Rethink immigration policy, as current policy may be contributing to shortages of key workers and deterring entrepreneurs who wish to start promising businesses in our country. Explore ways to foster “innovation-friendly” environments, such as regional cluster initiatives. Strengthen government counseling programs. The term “small business” applies to many different types of firms. To begin, the small business community encompasses an enormous range of “Main Street” stores and services we use every day, such as restaurants, dry cleaners, card shops and lawn care providers. When such a business fails, it is often replaced by a similar firm. The small business community also includes somewhat bigger firms—in industries such as manufacturing, consulting, advertising and auto sales—that may have more staying power than Main Street businesses, but still tend to stay relatively small, with under 250 employees. While these two kinds of small businesses contribute relatively little to overall employment growth, they are a steady source of mainstream employment. If economic conditions do not support the formation of new businesses to replace the ones that fail, there would be a significant net destruction of jobs and harm to local communities. Yet another type of small business has an explicit ambition for rapid growth. These high-growth companies are sometimes known as “gazelles.” According to the Small Business Administration, small businesses account for two-thirds of new jobs, and the gazelles account for much of this job creation. The most striking examples—such as Google and eBay—have tended to be in high-tech industries and were gazelles for a significant time before they graduated to be very large businesses. However, gazelles exist in all industry types and in all regions of the country, and the large majority are not grazing in the nation’s technology-dominated Silicon Valleys. According to one expert, the three largest industry categories for high-growth companies are restaurant chains, administrative services and health care companies. One non-high-tech example is Potbelly Sandwiches, a restaurant chain that began in Chicago. Another is the San Francisco-based Gymboree Corporation, a provider of child development programs and children’s clothing. Fostering the Development of High-Growth CompaniesHigh-growth small businesses represent only about 5 percent of total startups, making it important to determine how to spot and foster them. A key common characteristic is that growth is critically dependent on the entrepreneurs who start these companies; they are people on a mission, charismatic leaders who can inspire creativity and commitment from their staffs. The age of these firms is highly correlated with when their growth is highest. Generally, the most dramatic growth occurs after at least four years of existence—and coincidentally lasts about four years—before it slows again to a more typical pace for small businesses. Of course, some firms such as Google defy this pattern and continue to experience high growth for many years. Although dynamic small businesses can be found nearly everywhere and in many industries, some regions spawn more of them than others. These regions may have especially supportive features, such as a critical mass of potential workers with relevant skills, a social climate and network that encourage idea generation, locally available venture capital, or some combination of these factors. Unfortunately, attempts to anticipate which companies or even industries are likely to produce gazelles are prone to error. Thus, excessive emphasis on national industrial policies that favor specific industries are likely misplaced. Without knowing how to target assistance precisely, broad strategies, such as assistance with funding, knowledge, contacts and other essential resources, may be the best approach to fostering high-growth businesses. Such support has the added value of also aiding Main Street businesses. Many of the most promising policies focus on removing obstacles that hinder entrepreneurs with solid business plans from launching and expanding their businesses. Funding As a result of the burst of the dot.com bubble in early 2000 and the recent financial crisis, small businesses have found the availability of venture capital funds drastically diminished. The crisis has also made it more difficult to obtain funding from banks and other conventional means. These trends particularly affect the “missing middle” of small businesses—roughly, those with between 10 and 100 employees. The venture capital market. Historically, venture capital has financed only a relatively small portion of small businesses, but those financed have tended to be the ones with the greatest growth potential. In recent years, firms that eventually grew to where they could issue initial public stock offerings generally relied more heavily on venture capital financing than the average small business. The dollar value of venture capital deals funded today is only about one-fifth the size it reached at its peak. While the peak amount may have been too large, today’s value is probably too small. With their capital heavily invested in a small range of industries and locales, it seems likely that venture capital firms have missed a high proportion of potential investment opportunities. Further, “once burned, twice shy” funders have increasingly focused on larger, later-stage ventures. Consequently, mezzanine financing, which new companies need to survive and thrive in the critical early stages, is scarce. The funding problems partly stem from venture capital firms today having less money to invest. Some investors who formerly contributed to such firms have become more risk-averse, and worse performance figures have discouraged new investors. Lack of venture capital affects some industries more than others, and even some green energy companies—viewed by some as one of the nation’s more promising industry sectors—have moved to China, where financial support is more readily available. Bank lending. In contrast to large businesses, which can turn to capital markets for funding, many small businesses are dependent on banks for financing. Although the worst of the 2008–09 credit crunch is behind us, many small businesses still find it difficult to obtain bank loans. Community banks, a key source of small business financing, have been hard hit by losses in commercial real estate, which have limited their lending capacity. Further, many small business owners who historically would have used real estate assets as collateral for expansion loans can no longer do so because of declines in real estate prices. In addition, small businesses that have, in the past, used credit cards to purchase equipment and supplies have been hindered by reductions in credit limits. Overall economic conditions The high degree of uncertainty currently surrounding the economic and financing climate may have prompted many entrepreneurs and would-be entrepreneurs to hold off on growth plans. Despite their reputation as high-flying risk-takers, good entrepreneurs take only calculated risks, where the benefits outweigh the dangers. Uncertainties about the future trajectory of the economy merely increase risk without raising potential rewards. Government policies Government policies affect the climate for small businesses in many ways. For example, small businesses face substantial hurdles when entering the complicated world of federal grants and contracts. At the state level, severe budget shortfalls mean that even well-designed initiatives to boost small businesses may founder. The Small Business Administration (SBA) assists the full continuum of small businesses through a variety of means. These include: an $80 billion loan guarantee portfolio; specialized counseling and training centers; specialized business development programs targeting the socially and economically disadvantaged; oversight to ensure that at least 23 percent of federal government contracts go to small businesses (with certain preferences for minority and women-owned businesses); and the Small Business Innovation Research and Small Business Investment Companies programs. The Obama administration is attempting to broaden support for small businesses by bringing the SBA into multi-agency initiatives that tackle common problems. For example, the Departments of Energy, Commerce, Housing and Urban Development, Education, and Labor, along with the National Science Foundation and the SBA, are supporting a five-year, nearly $130 million Energy Regional Innovation Cluster. Strength of “social capital” Through the 1990s, the United States was a worldwide leader in fostering innovation and entrepreneurship and reaped the reward of employment growth. Current international comparisons suggest that we are now closer to tenth place among some 70 nations in our ability to support innovation. Much of what has kept our nation from remaining in the top spot appears to relate to insufficient cultural support for entrepreneurship. Strong social networks in specific geographic regions appear to substantially bolster the growth of innovative businesses. These networks are built around entrepreneurial dealmakers who serve as the nodes of the network, forming connections among researchers, entrepreneurs and investors. Unfortunately, many regions and industries lack strong networks. Access to decision-making information. Entrepreneurs need an array of information and advice about how to tackle the problems that arise at different stages in business development. The SBA reports that companies that have taken advantage of their long-term counseling programs, for example, have higher growth than companies that have not. Opportunity for all. Social networks are self-selecting, and some people have to work extra hard to gain entry to a region’s network of entrepreneurs. While various organizations exist to help women and people of color access entrepreneurial skills and information, these efforts may not suffice. Under-representation of any group presumably would filter out a number of potential high-growth companies. Workforce issues A long-time strength of the American workforce, worker mobility has declined. This trend has been attributed in part to an aging population and in part to the current difficulty people have in selling their homes. Businesses report difficulty finding employees with the right training, especially at the technician level, where straightforward vocational training could help. Global competition Increasing global competition for good projects, entrepreneurs and capital is a positive trend from an international perspective, but runs counter to the national goal of promoting rapid growth in U.S. industry and employment. Today, many entrepreneurs can choose among starting a business here, in their home country, or even in a third, more hospitable nation. At the same time, current U.S. immigration policy hinders entrepreneurs from coming here to launch their companies. A recent report from The Brookings- Duke Immigration Policy Roundtable concluded that “educated workers with the knowledge and skills to innovate are critical” to the United States and recommended increasing the annual number of skilled visas. Policy Goals for Small BusinessMeasuring Results More work is needed to identify key policy goals and priorities related to small business success. Critically, what would constitute “improvement” in public policy regarding small business employment, and how would we measure it? Clearly, increasing the total number of jobs created each year (by both small and large businesses, net of job destruction) would be a positive outcome, all else being equal. Another potential goal would be improving the “quality” of the jobs created, as measured by average compensation or by job creation in new industries or geographic areas where unemployment is high. Creating “good jobs” that bring generous compensation would seem to be always desirable, but this outcome could conflict with other social goals, for example, if the jobs created required skills out of the reach of groups that are traditionally difficult to employ. Slowing job destruction could be as important as increasing the creation of new jobs, but discouraging layoffs without increasing performance would do more harm than good. The trick is to raise the quality of marginal firms so that their improved performance allows them to retain employees they would otherwise have to let go. A final key factor in setting policy goals that would support small businesses is measuring the cost to taxpayers of the initiatives that flow from the goals. This includes the subsidy cost contained in the federal budget, as well as costs and tradeoffs in society at large. Changing Key Policies Small businesses face both short-run and long-run challenges. With regard to the former, many small businesses have been hard hit by the recession and appear to be lagging behind larger businesses in their recovery. The cyclical struggles of this sector in part reflect the dependence of many small firms on the still-strained banking system for their financing; they also reflect the high toll that our extremely soft labor markets have taken on demand for Main Street goods and services. Thus, government policies aimed at broadly bolstering the recovery and further strengthening the financial system will yield important benefits to small businesses. The government, in conjunction with the private sector, can also take steps that will foster an economic environment that is supportive of entrepreneurship and economic growth over the long run. Specific policy steps that might help small businesses (and, in many cases, large businesses) include: Improve access to public and private capital. Implementing serious financial reform will reduce the likelihood that we will see a repeat of the recent credit cycle that has been so problematic for the small business sector. When credit market disruptions do occur, policymakers should be attentive to whether temporary expansions of the SBA loan guarantee program are needed to sustain lending to creditworthy borrowers. The SBA should also consider expanding the points of access to its loan programs through an expansion of its lending partners. Finally, the SBA (or a similar entity) might encourage venture capital funds to broaden their investments beyond familiar areas by systematically bringing these investors together with entrepreneurs from neglected geographic regions and business sectors. Reexamine corporate tax policy. More thinking is needed about whether provisions in our tax code discourage small business development in a way that is harmful to the broader economy and that places the United States at a relative disadvantage internationally. For example, Congress might consider whether it would be beneficial, on net, to lower employment taxes as a way of spurring hiring at businesses with high-growth potential. In addition, some analysts believe there would be gains from increasing tax credits for research and development and further lowering taxes on capital equipment. A design priority in all cases should be simplicity, as complicated rules can limit take-up among smaller firms that do not have extensive accounting or legal expertise. Promote education and research. Entrepreneurs report difficulty in finding workers with the skills they need for manufacturing, technology and other jobs that do not require four-year college degrees. Access to such educational opportunities, including tailored vocational training, should be affordable and ubiquitous. At the university level, improvements are needed in the way academic research is brought to the commercial market. Continued public and private support for basic research might be wise, particularly if we are in a trough between waves of innovation, as some analysts believe. The large investments by the National Science Foundation, National Institutes of Health, Defense Advanced Research Projects Agency, and other ambitious public and private programs laid the groundwork for many of the high-growth businesses of today. It may be worth exploring whether support for research in “softer” areas than the sciences might do an equal or better job of inspiring innovations. Rethink immigration policy. A reconsideration of limits on H1-B visas might help entrepreneurs struggling with shortages of workers with particular skills. In addition, current immigration policy discourages immigrants who want to establish entrepreneurial businesses in America. Any efforts to expand immigration are frequently perceived as “taking jobs away from Americans,” but studies have shown that new businesses create jobs for Americans. Explore ways to foster “innovation-friendly” environments. Some regions of the United States clearly do a better job of encouraging innovation. Silicon Valley is the classic example, but there may be as many as 40 such clusters scattered around the country. While clusters often arise organically, typically near major universities, some states have made an explicit commitment to innovation and entrepreneurship. Examples include the Massachusetts Technology Collaborative and California’s Biological Technologies Initiative, involving community colleges statewide. Federal, state and local policymakers should keep a keen eye on ways of adapting best practices from these initiatives as information becomes available about which elements are most effective. Strengthen government counseling programs. The SBA might do more to expand and tailor its already successful growth counseling programs to better meet the needs of both Main Street and potential high-growth businesses, as well as firms at different developmental stages. Any effort to expand small businesses’ opportunities for federal grants and contracts should be accompanied by significant streamlining of the application process. Downloads Download Policy Brief Authors Martin Neil BailyKaren DynanDouglas J. Elliott Full Article
small The end of grand strategy: America must think small By webfeeds.brookings.edu Published On :: Mon, 13 Apr 2020 18:46:33 +0000 Full Article
small The end of grand strategy: America must think small By webfeeds.brookings.edu Published On :: Mon, 13 Apr 2020 18:46:33 +0000 Full Article
small The end of grand strategy: America must think small By webfeeds.brookings.edu Published On :: Mon, 13 Apr 2020 18:46:33 +0000 Full Article
small Not just for the professionals? Understanding equity markets for retail and small business investors By webfeeds.brookings.edu Published On :: Fri, 15 Apr 2016 09:00:00 -0400 Event Information April 15, 20169:00 AM - 12:30 PM EDTThe Brookings InstitutionFalk Auditorium1775 Massachusetts Ave., N.W.Washington, DC 20036 Register for the EventThe financial crisis is now eight years behind us, but its legacy lingers on. Many Americans are concerned about their financial security and are particularly worried about whether they will have enough for retirement. Guaranteed benefit pensions are gradually disappearing, leaving households to save and invest for themselves. What role could equities play for retail investors? Another concern about the lingering impact of the crisis is that business investment and overall economic growth remains weak compared to expectations. Large companies are able to borrow at low interest rates, yet many of them have large cash holdings. However, many small and medium sized enterprises face difficulty funding their growth, paying high risk premiums on their borrowing and, in some cases, being unable to fund investments they would like to make. Equity funding can be an important source of growth financing. On Friday, April 15, the Initiative on Business and Public Policy at Brookings examined what role equity markets can play for individual retirement security, small business investment and whether they can help jumpstart American innovation culture by fostering the transition from startups to billion dollar companies. You can join the conversation and tweet questions for the panelists at #EquityMarkets. Video Keynote address by Richard G. Ketchum Panel DiscussionKeynote address by Roger Ferguson Audio Not just for the professionals? Understanding equity markets for retail and small business investors Transcript Uncorrected Transcript (.pdf) Event Materials Equity Markets Retirement Security 2016 Apr 15 (2)20160415_equity_markets_transcript Full Article
small Toward a Containment Strategy for Smallpox Bioterror: An Individual-Based Computational Approach By webfeeds.brookings.edu Published On :: Sun, 01 Dec 2002 00:00:00 -0500 Abstract An individual-based computational model of smallpox epidemics in a two-town county is presented and used to develop strategies for bioterror containment. A powerful and feasible combination of preemptive and reactive vaccination and isolation strategies is developed which achieves epidemic quenching while minimizing risks of adverse side effects. Calibration of the model to historical data is described. Various model extensions and applications to other public health problems are noted. Downloads Download Authors Derek CummingsDonald S. BurkeJoshua M. EpsteinRamesh M. SingaShubha Chakravarty Full Article
small Toward a Containment Strategy for Smallpox Bioterror : An Individual-Based Computational Approach By webfeeds.brookings.edu Published On :: Tue, 01 Jun 2004 00:00:00 -0400 Brookings Institution Press 2004 55pp. In the United States, routine smallpox vaccination ended in 1972. The level of immunity remaining in the U.S. population is uncertain, but is generally assumed to be quite low. Smallpox is a deadly and infectious pathogen with a fatality rate of 30 percent. If smallpox were successfully deployed as an agent of bioterrorism today, the public health and economic consequences could be devastating. Toward a Containment Strategy for Smallpox Bioterror describes the scientific results and policy implications of a simulation of a smallpox epidemic in a two-town county. The model was developed by an interdisicplinary team from the Johns Hopkins Bloomberg School of Public Health and the Brookings Institution Center on Social and Economic Dynamics, employing agent-based and other advanced computational techniques. Such models are playing a critical role in the crafting of a national strategy for the containment of smallpox by providing public health policymakers with a variety of novel and feasible approaches to vaccination and isolation under different circumstances. The extension of these techniques to the containment of emerging pathogens, such as SARS, is discussed. About the Authors: Joshua M. Epstein and Shubha Chakravarty are with the Brookings Institution. Derek A. T. Cummings, Ramesh M. Singha, and Donald S. Burke are with the Johns Hopkins Bloomberg School of Public Health. ABOUT THE AUTHORS Derek Cummings Donald S. Burke Joshua M. Epstein Ramesh M. Singa Shubha Chakravarty Downloads Sample Chapter Ordering Information: {9ABF977A-E4A6-41C8-B030-0FD655E07DBF}, 978-0-8157-2455-1, $19.95 Add to Cart Full Article
small Campaign Reform in the Networked Age: Fostering Participation through Small Donors and Volunteers By webfeeds.brookings.edu Published On :: Thu, 14 Jan 2010 10:30:00 -0500 Event Information January 14, 201010:30 AM - 12:00 PM ESTFalk AuditoriumThe Brookings Institution1775 Massachusetts Ave., NWWashington, DC Register for the EventThe 2008 elections showcased the power of the Internet to generate voter enthusiasm, mobilize volunteers and increase small-donor contributions. After the political world has been arguing about campaign finance policy for decades, the digital revolution has altered the calculus of participation.On January 14, a joint project of the Campaign Finance Institute, American Enterprise Institute and the Brookings Institution unveiled a new report that seeks to change the ongoing national dialogue about money in politics. At this event, the four authors of the report will detail their findings and recommendations. Relying on lessons from the record-shattering 2008 elections and the rise of Internet campaigning, experts will present a new vision of how campaign finance and communications policy can help further democracy through broader participation. Video Thomas MannMichael MalbinAnthony CorradoNorm Ornstein Audio Campaign Reform in the Networked Age: Fostering Participation through Small Donors and Volunteers Transcript Transcript (.pdf) Event Materials 20090114_campaign_finance Full Article
small Green economies offer small islands new economic and ecological opportunities By www.treehugger.com Published On :: Tue, 10 Jun 2014 14:19:44 -0400 Environmental sustainability doesn’t have to come at the expense of economic development. Full Article Business
small Angular small house is inspired by Dutch and Japanese design By www.treehugger.com Published On :: Thu, 25 Oct 2018 13:39:26 -0400 Clad with reclaimed cedar, this modern and quirky house fits on a small footprint. Full Article Design
small Multi-layered urban housing prototype packs in plenty of great small space ideas By www.treehugger.com Published On :: Wed, 02 Oct 2013 07:00:00 -0400 Using a series of overlapping mezzanines and spaces, this accessible, urban housing prototype explores the possibilities of living small but comfortably in the city. Full Article Design