Corrosion by ammonia/amine salts in hydrocarbon streams such as distillation overhead streams that contain a mineral acid and water can be prevented, avoided or minimized by adding certain strong amines to the streams. The amines have a pKa between about 10.5 to about 12 and include, but are not necessarily limited to, dimethylamine, diethylamine, dipropylamine, diisopropyl-amine, di-n-butylamine, diisobutylamine, di-sec-butylamine, di-tert-butylamine, pyrrolidine, piperidine, and combinations thereof. If the hydrocarbon stream further includes a nitrogen-containing compound such as ammonia, a tramp and/or a residual amine which can form a corrosive salt with the mineral acid, then the added amine is a stronger base than the tramp or residual amine, if present. The amount of added amine is greater than total amount of nitrogen-containing compound, so that any corrosive salts formed are less corrosive than the salts that would otherwise form from the ammonia and/or tramp amine.

Lubrication additives of the current invention require formation of emulsions in base lubricants, created with an aqueous salt solution plus a single-phase compound such that partitioning within the resulting emulsion provides thermodynamically targeted compounds for boundary layer organization thus establishing anti-friction and/or anti-wear. The single-phase compound is termed “boundary layer organizer”, abbreviated BLO. These emulsion-contained compounds energetically favor association with tribologic surfaces in accord with the Second Law of Thermodynamics, and will organize boundary layers on those surfaces in ways specific to the chemistry of the salt and BLO additives. In this way friction modifications may be provided by BLOs targeted to boundary layers via emulsions within lubricating fluids, wherein those lubricating fluids may be water-based or oil-based.

An oil-soluble lubricating oil additive composition comprising (a) at least 3.5 wt-% of at least one friction modifier selected from the group consisting of fatty acids, fatty acid amides, fatty acid esters, and alkane diols which have a melting point of greater than 30° C.; (b) at least 10 wt-% actives dispersant; and (c) a sufficient amount of surfactant to make said additive composition haze-, sediment-, and skin-free, provided that said additive composition contains at least 150 mm surfactant per kg of said lubricating oil additive composition.

It is known by the inventor that a universal synthetic lubricant additive that can greatly enhance the performance standards of existing lubricants, petroleum based or synthetic, imparts a new and desirable property not originally present in the existing oil or it reinforces a desirable property already possessed in some degree can greatly benefit the consumer. Although additives of many diverse types have been developed to meet special lubrication needs, their principal functions are relatively few in number. This universal synthetic lubricant additive (invention) with micro lubrication technology, when used as directed will reduce the oxidative or thermal degradation of the host oil, substantially reduce the deposition of harmful deposits in lubricated parts, minimize rust and corrosion, control frictional properties, reduce wear, temperature, sludge, varnishes and prevent destructive metal-to-metal contact, reduce fuel consumption and harmful emissions while improving performance through increased horsepower and torque.

The present invention relates to a method of driveline device by supplying to the driveline device a lubricating composition containing an oil of lubricating viscosity and an antiwear package, wherein the antiwear package includes: (a) derivatives of a carboxylic acid (typically a hydroxycarboxylic acid); and (b) a phosphorus compound. The invention further provides lubricating compositions containing an oil of lubricating viscosity and an antiwear package, wherein the antiwear package includes (a) derivatives of a carboxylic acid (typically a hydroxycarboxylic acid); and (b) an amine or metal salt of a phosphorus compound that is either (i) a hydroxy-substituted di-ester of (thio)phosphoric acid, or (ii) a phosphorylated hydroxy-substituted di- or tri-ester of (thio)phosphoric acid.

A system for loading/unloading sheets is disclosed, some of which also being of metal, and handling method thereof, serving a laser cutting center. The system includes a pair of rails (1, 2), supported at a preset height above a feeding tray (T) of the cutting center, whereon at least one Cartesian robotized hand is movably mounted, capable of moving along horizontal axes X and Y as well as along a vertical axis Z, mutually orthogonal, and including at least two bridge cranes (3, 4) sliding along the rails (1, 2) each of which supports at least one pair of robotized hands (5-8), and the robotized hands (5-8) have an electromagnetic pick-up head which may be coupled with a suction-cup device (103). Feeding tray (T) consists of bars whereon small tesserae (204) of ceramic material are fitted.

A network component comprising at least one processor coupled to a memory and configured to exchange security information using a plurality of attributes in a management entity (ME) in an optical network unit (ONU) via an ONU management control interface (OMCI) channel, wherein the attributes provide security features for the ONU and an optical line terminal (OLT). Also included is an apparatus comprising an ONU configured to couple to an OLT and comprising an OMCI ME, wherein the OMCI ME comprises a plurality of attributes that support a plurality of security features for transmissions between the ONU and the OLT, and wherein the attributes are communicated via an OMCI channel between the ONU and the OLT and provide the security features for the ONU and the OLT.

The disclosure provides a method and a system for detecting a fiber fault in a Passive Optical Network (PON). The system comprises an optical path detection device, a Wavelength Division Multiplexing (WDM) coupler, a wavelength selection coupler, a branch fiber selector and a wavelength selection router. The detection system is attached to an original PON system, without influencing the operation of the original system while performing the detection. With the disclosure, the problem of being unable to determine whether there is a fault in a branch fiber due to the loss of an optical path detection reflection signal is solved, the branch fiber with a fault can be quickly located and fixed, thus the operational and maintenance costs of an operator are reduced.

A system and method are disclosed for transporting deterministic traffic in a gigabit passive optical network. A system that incorporates teachings of the present disclosure may include, for example, an Optical Line Termination (OLT) for exchanging data traffic in a Gigabit Passive Optical Network (GPON) having a controller programmed to generate a timeslot schedule for transport of a desired bandwidth of constant bit rate (CBR) data traffic by selecting one or more timeslots from periodic frame clusters operating according to a GPON Transmission Convergence (GTC) protocol. Additional embodiments are disclosed.

An optical transceiver has a communications mode and an optical time domain reflectometer (OTDR) mode. The transceiver comprises a transmitter channel and a receiver channel operable, in the communications mode, to respectively transmit and receive communications signals through respective external optical fibers. The transceiver also comprises a guide arrangement for guiding, in the OTDR mode, a reflected OTDR signal along a path from the transmitter channel into the receiver channel. A method of obtaining test data for an optical fiber in an optical data communications subsystem is also disclosed.

Embodiments of the present disclosure provide methods for allocating bandwidth to a plurality of traffic containers of a passive optical network. The method comprises receiving upstream data from a plurality of traffic containers of the passive optical network and passing the upstream data to a traffic manager. The method further comprises dynamically changing the allocated bandwidth based at least in part on the amount of the upstream data stored in one or more queues of the traffic manager.

Provided is a polarization separation device which converges filter coefficients used in polarization separating process more quickly. The polarization separation device according to the present invention comprises: a first filter means 11 which applies filtering process on each of first and second input signals, which are detected from an received optical signal, with elements of a characteristic matrix representing the inverse characteristics of an optical transmission path as filter coefficients, and uses each of the filtered signals to output a first output signal; a second filter means 12 which applies filtering process on each of the first and second input signals with the other elements of the characteristic matrix as filter coefficients, and uses each of the filtered signals to output a second output signal; a filter coefficient update means 13 which updates the first filter coefficients using a relation between the elements of the characteristic matrix so as to further reduce both error signals of the first and second output signals; and a filter coefficient update means 14 which updates the second filter coefficients using the relation between the elements of the characteristic matrix so as to further reduce both error signals to the first and second output signals.

An optical transceiver that attenuates the EMI radiation leaked therefrom is disclosed. The optical transceiver includes a top cover and the bottom base to form a cavity into which a TOSA, a ROSA, and a circuit are set. At least one of the top cover and the bottom base provides a combed structure in a rear portion of the optical transceiver, where the combed structure has a plurality of T-shaped fins to attenuate the EMI radiation.

An optical transceiver that reduces the EMI radiation leaked therefrom is disclosed. The optical transceiver includes a top cover and the bottom base to form a cavity into which a TOSA, a ROSA, and a circuit are set. The top cover provides a combed structure in a rear portion thereof, where the combed structure has a plurality of fins with a distance preferably less that quarter wavelength λ/4 of the noise wavelength to be reduced. The combed structure operates as a short stub for the electromagnetic wave traveling longitudinally in the cavity.

An apparatus and method for fault indication and localization in a Passive Optical Network (PON) comprising a multistage power splitter (100, 200, 300) with at least one 1:N splitter (120, 221, 222, 321, 322) followed by N items of 2:M splitters (131, 132, 231-233, 331-336), wherein N and M are integers greater than 1. The apparatus also comprises an Optical Time Domain Reflectometry (OTDR) device (110, 210, 310) capable of inserting an OTDR signal into the power splitter (100, 200, 300), and adapted to insert the OTDR signal between the first stage of the at least one 1:N splitter (120, 221, 222, 321, 322) and the second N items of 2:M splitters (131, 132, 231-233, 331-336).

An optical line termination node has a first connection arrangement for connecting a working fiber, a second connection arrangement for connecting a protection fiber, a transceiver arrangement having first primary link and a first secondary link, and protection switching means configured for being switched either in a working operating state or in a protection operating state.

This invention relates to provisioning wavelength-selective switches and reconfigurable optical add-drop multiplexers to minimize the bandwidth narrowing effect from the optical filters. Novel architectures and methods are disclosed that can significantly reduce bandwidth-narrowing on channels in a reconfigurable WDM network where a large number of optical filter elements are cascaded. Instead of blocking unused channels as in the prior art, unused channels are selectively provisioned depending on the state of their adjacent channels. Unused adjacent channels of an active channel are provisioned to follow the same path as the active channels. As each channels is deployed, the channel frequency is selected so as to minimize bandwidth narrowing.

An optical transceiver of one embodiment includes a transmitter optical subassembly to transmit an optical signal, a receiver optical subassembly to receive an optical signal, a mother board, a daughter board, and a housing. The mother board mounts electronic circuits that electrically communicate with the optical transmitter optical subassembly and the receiver optical subassembly. The daughter board mounts other electronic circuits that electrically communicate with the optical transmitter optical subassembly and the receiver optical subassembly. The daughter board has an extra area mounting a portion of the other electronic circuits. The housing defines a space for installing the optical transmitter optical subassembly, the receiver optical subassembly, the mother board, and the daughter board. The extra area is disposed outside the space.

An optical receiver circuit is disclosed in which a number of electrical signals are processed to extract data encoded therein. The electrical signals may be compared during the process to selectively remove one or more waveforms from one or more corresponding electrical signals. Various data signals, each including one or more waveforms, may then be processed to extract the encoded data. The optical receiver circuit reduces, or eliminates, electrical offsets which may be present in one or more of the electrical signals to reduce corresponding errors in the encoded data signals.

A toolholder assembly includes a toolholder body having a coolant passage and a cutting insert seated within a recess of the body. The cutting insert includes an insert orifice extending between a top face and a bottom face that aligns with the coolant passage. A lock pin includes a lock pin orifice that aligns with and is in fluid communication with the coolant passage of the body. The lock pin orifice has an outlet port to allow the fluid to flow through the lock pin orifice and exit through the outlet port. A lock pin ring includes a coolant port in fluid communication with the outlet port of the lock pin to effectively discharge cooling fluid in the direction of a cutting area of the cutting insert.

A rotary cutting tool, such as a milling cutter (10) includes a central hub (12), a cutting rim (14) and a plurality of spokes (22) connecting the central hub (12) to the cutting rim (14). Each spoke (22) is separated by an opening (32) and polygonal in cross-sectional shape formed by two side walls (22a, 22b), two front walls (22c, 22d) and a rear wall (22e). One of the side walls (22a) of each spoke (22) is formed at a pitch angle (42) with respect to a central axis (11) of the cutting tool (10) that is sufficient to cause lift of chips through the opening (32), thereby providing effective chip evacuation during a material removal operation.

A propulsion apparatus for an endoscope includes a propulsion assembly for mounting on a tip device of the endoscope, for propulsion in a body cavity. First and second wire devices are disposed to extend from the tip device in a proximal direction, having a coil winding, for rotating to drive the propulsion assembly. First and second motors are connected with proximal ends of respectively the first and second wire devices, for rotating the first and second wire devices. A timer is actuated if a speed difference between rotational speeds of the first and second motors becomes equal to or more than a reference speed value, for measuring an elapsed time. A break detector detects breakage of the first wire device if the elapsed time becomes equal to or longer than a predetermined time. A controller controls the first and second motors in response to an output of the break detector.

A transmissive diffraction grating includes a polarization conversion layer, a first diffractive layer disposed on one surface side of the polarization conversion layer, and a second diffractive layer disposed on the other surface side of the polarization conversion layer. Both the first diffractive layer and the second diffractive layer include refractive index modulation structures arranged with a period P in a first direction, and diffraction efficiency for a TE polarized light component is higher than a diffraction efficiency for a TM polarized light component.

The present disclosure relates to an improved device and methods for adapting to a laser diffraction apparatus used for measuring particle size distribution and density of the plume of a powder composition emitted from a dry powder inhaler.

An adaptive optics scanning system using a beam projection module with four or more axes of motion that can project and control the position and angle of a beam of light to or from an adaptive optics element. The adaptive optics scanning system is compact in size, overcoming the challenges of a traditional lens and mirror based pupil relay design. The adaptive optics scanning system has little to no dispersion, chromatic aberration, and off-axis aberration for improved optical performance. The system and methods for calibrating and optimizing the system are described. A modular adaptive optics unit that scans and interfaces an adaptive optics element is described.

An additional electric power receiving method replacing conventional grounding with a negative voltage source includes the step of transmitting electromagnetic wave or current from a power supply source to a rectifier, wherein a grounding end of the rectifier is in electrical communication with the negative voltage source, and the negative voltage source is selected from a negative potential intrinsic of an organism. A device applicable to the electric power receiving method includes a rectifier having an input end and two output ends, wherein the input end is in electrical communication with a power supply source, and rectified direct current is transmitted from the output ends. With the method and device, not only an increase in additional electric power obtained is achieved, but conversion efficiency and stability of current and electromagnetic wave is enhanced.

The present invention is applied to a frequency converter used for a receiver. The frequency converter according to the present invention includes an LO signal generator (11) that generates an LO signal and outputs the LO signal; and a mixer (10) that multiplies a received signal that has been band-limited to a usable bandwidth of said receiver by the LO signal so as to convert the frequency of the received signal and outputs the resultant signal. Said LO signal generator is capable of varying a phase resolution.

Among many embodiments, a power conversion apparatus and a method for converting power are disclosed. The power conversion apparatus may include switching components configured to create an alternating current; a preemptive detector arranged and configured to provide, in advance of the alternating current reaching a zero-crossing, a control signal responsive to the alternating electrical current approaching the zero-crossing; and a controller configured, at least in part, to change a state of the switching components before the zero crossing, in response to the control signal.

Provided is a power conversion system that includes a first transformer adapted to be connected to an AC network, the first transformer including a first primary winding and two first secondary windings, and two power converters, each being connected to a first respective secondary winding. The system further includes a second transformer and a secondary electrical device, the second transformer including a second primary winding and two second secondary windings, each second secondary winding being connected to a respective first secondary winding, and the secondary device being connected to the second primary winding.

A Low Forward Voltage Rectifier (LFVR) circuit includes a bipolar transistor, a parallel diode, and a capacitive current splitting network. The LFVR circuit, when it is performing a rectifying function, conducts the forward current from a first node to a second node provided that the voltage from the first node to the second node is adequately positive. The capacitive current splitting network causes a portion of the forward current to be a base current of the bipolar transistor, thereby biasing the transistor so that the forward current experiences a low forward voltage drop across the transistor. The LFVR circuit sees use in as a rectifier in many different types of switching power converters, including in flyback, Cuk, SEPIC, boost, buck-boost, PFC, half-bridge resonant, and full-bridge resonant converters. Due to the low forward voltage drop across the LFVR, converter efficiency is improved.

Provided are an optical pickup device and an optical disk drive including the same. The optical pickup device includes a quarter-wave plate (QWP) that is disposed parallel to an objective lens and a reflection mirror that reflects a beam back onto the QWP after the beam passed through the QWP. The optical pickup device also includes a polarization mirror that is disposed between the objective lens and the QWP, and which reflects the beam which is generated from a light source onto the QWP, and allows the beam reflected by the reflection mirror to pass through to the objective lens.

According to one embodiment, a multilayer optical recording medium including a substrate, a guide layer group that is provided on the substrate and has guide layers in which positional information in a radial direction is recorded, and a recording layer group that is provided on the substrate and has recording layers in which information can be recorded. In the recording layer group, positional information of the recording layers associated with the positional information recorded in the guide layers and control information of the optical device where reflected light volumes of the laser beams on the guide layers and the recording layers become maximum at the positions in the radial direction are recorded at the positions in the radial direction of the recording layers.

In a heat-assisted magnetic recording hard disk drive, one or more thermally conductive features are incorporated to assist with dissipation of heat from a laser module that comprises a laser and a submount. The submount may be coupled to the slider with solder covering a wider adhesive area for enhanced conduction of heat away from the laser module and to the slider, one or both of the submount and the laser may include a surface coating that increases the thermal radiation of the corresponding component, and/or one or both of the submount and the laser may include fins configured to transfer heat from the corresponding component. Further, a HAMR HGA may be configured such that the submount is coupled directly to the suspension flexure using a thermally conductive material, for conduction of heat away from the laser module and to the flexure.

The relative health of data storage drives may be determined based, at least in some aspects, on data access information and/or other drive operation information. In some examples, upon receiving the operation information from a computing device, a health level of a drive may be determined. The health level determination may be based at least in part on operating information received from a client entity. Additionally, a storage space allocation instruction or operation may be determined for execution. The allocation instruction or operation determined to be performed may be based at least in part on the determined health level.

A shoulder orthosis is provided having an arm support and an optional arm spacer connected to the arm support. The arm support includes an arm retainer and a supportive strapping system. One optional arm spacer includes a pair of individual pillows which are attachably combinable with one another at a first face of the first individual pillow and a face of the second individual pillow to form one combined pillow having a first shape. The individual pillows are alternately attachably combinable with one another at a second face of the first individual pillow and the face of the second individual pillow to form another combined pillow having a second shape different from the first shape.

The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a biocompatible adhesive for use in an oral environment, wherein the adhesive is in a non-tacky state when dry and becomes adherent upon contact with liquids.

An orthopedic cast removal tool and method uses an unmodified, typically cordless, rotary impact driver and a embedded wire to cut through an orthopedic cast for removal. By merging it with a slotted spacer block specifically for this cast removal purpose, an ergonomic tool is provided which allays fears of orthopedic patients. When rotating and encountering high resistance of the plaster or fiberglass material of the cast, the cordless rotary impact driver does not bog down; since it seamlessly engages impact action, which offers an order of magnitude or more torque multiplication via short frequent pulses (several per second) to overcome this torque resistance. Thus a high amount of torque with very little reaction force is made available to cut through a cast while affording the technician good control. The cast is cut very rapidly with little dust creation and no jostling of the patient.

This disclosure provides methods of controlled polymerization of cyclic compounds catalyzed by carbene derivatives having a general formula as shown below, and to obtain a biodegradable polymeric material having a large molecular weight, a narrow dispersity, and no metallic impurity.

A composition comprising an extruded inorganic support comprising an oxide of a metal or metalloid, and at least one catalytically active metal, wherein the extruded inorganic support has pores, a total pore volume, and a pore size distribution, wherein the pore size distribution displays at least two peaks of pore diameters, each peak having a maximum, wherein a first peak has a first maximum of pore diameters of equal to or greater than about 120 nm and a second peak has a second maximum of pore diameters of less than about 120 nm, and wherein greater than or equal to about 5% of a total pore volume of the extruded inorganic support is contained within the first peak of pore diameters.

The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

Disclosed is a novel photosensitizer based on polymer derivatives-photosensitizer conjugates for photodynamic therapy capable of being selectively accumulated in cancerous tissues and producing singlet oxygen or free radical by laser irradiation. The polymer derivatives-photosensitizer conjugates for photodynamic therapy are prepared as nano-sized particles, and have excellent selection and accumulation ratio for cancerous tissues. The photosensitizer conjugates can produce singlet oxygen or free radical by a specific laser wavelength. Owing to the excellent selection and accumulation ratio for cancerous tissues, the conjugates minimizes photo-cytotoxicity of the conventional photosensitizer having a low molecular amount. Accordingly, the conjugates are very useful as a photosensitizes for photodynamic therapy with reduced side effects and excellent therapeutic effectiveness.

An adhesive composition for use in adhering insulation panels to roofing substrates and roofing membranes to the insulation panels include two components that are mixed prior to application on the roofing substrate. The first component may include a renewable polyol and catalyst. The renewable polyol is selected from any non-petroleum based polyol that is derived from a renewable source. The second component includes isocyanate, and may also include a polyol and a catalyst. The isocyanate and the polyol may each be any non-petroleum based isocyanate or polyol that is derived from a renewable source.

The present invention provides stable aqueous thermosetting binder compositions having a total solids content of 15 wt. % or higher, preferably, 20 wt. % or higher, and having extended shelf life comprising one or more reducing sugar, one or more primary amine compound, and one or more stabilizer acid or salt having a pKa of 8.5 or less. The total amount of stabilizer used may range from 5 to 200 mole %, based on the total moles of primary amine present in the binder. The stabilizer may be an organic stabilizer chosen from a monocarboxylic acid, a dicarboxylic acid, a fatty acid, an acid functional fatty acid ester, an acid functional fatty acid ether, or an inorganic stabilizer chosen from a mineral acid, a mineral acid amine or ammonia salt, and a Lewis acid, and mixtures thereof. The compositions can be used to provide binders for substrate materials including, for example, glass fiber.

The present invention relates to a crosslinked lignin comprising a lignin structure having methylene or ethylene linking groups therein crosslinking between phenyl ring carbon atoms, wherein said crosslinked lignin is crosslinked to an extent that it has a number-average molecular weight of at least 10,000 g/mol, is melt-processible, and has either a glass transition temperature of at least 100° C., or is substantially soluble in a polar organic solvent or aqueous alkaline solution. Thermoplastic copolymers containing the crosslinked lignin are also described. Methods for producing the crosslinked lignin and thermoplastic copolymers are also described.

The present disclosure provides a polyester toner resin comprising a polyhydroxylated cardanol derivative, that may be used in manufacturing an emulsion aggregation (EA) toner for imaging devices.

A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized polysaccharide containing pendant aldehyde groups with a water-dispersible, multi-arm amine is described. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a more rapid degradation time, such as the prevention of undesired tissue-to tissue adhesions resulting from trauma or surgery.

The present disclosure provides a polyester toner resin comprising a polyhydroxylated thymol derivative that may be used in manufacturing an emulsion aggregation (EA) toner for imaging devices.

A hydrogel tissue adhesive having decreased gelation time and decreased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide containing aldehyde groups with a water-dispersible, multi-arm amine in the presence of a thiol additive. The thiol additive accelerates the process to form the hydrogel and accelerates the degradation of the hydrogel formed. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, such as a hemostat sealant or to prevent undesired tissue-to-tissue adhesions resulting from trauma or surgery.

The invention relates to a bioactive hydrogel as a hybrid material of heparin and star-branched polyethylene glycol with functionalized end groups, wherein the heparin is bound directly by reaction of the carboxyl groups activated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimides/N-hydroxysulfosuccinimide (EDC/s-NHS) with the terminal amino groups of the polyethylene glycol covalently by amide bonds.