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Synthesis of alkynyl sulfides via base-promoted nucleophilic ring-opening of α-bromostyrene sulfonium salt

Org. Biomol. Chem., 2024, 22,2953-2957
DOI: 10.1039/D4OB00203B, Communication
Junqi Zhou, Ziyu Wang, Hanmiao Xu, Mengke Su, Jian Wen
An effective method for synthesizing various alkynyl sulfides has been developed using tetramethylene sulfoxide as a sulfur source through base-promoted nucleophilic ring-opening reactions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Additive-free oxychlorination of unsaturated C–C bonds with tert-butyl hypochlorite and water

Org. Biomol. Chem., 2024, 22,3080-3085
DOI: 10.1039/D4OB00003J, Paper
Duyi Shen, Chaoyue Sun, Yun Han, Zhen Luo, Ting Ren, Qin Zhang, Wenting Huang, Jianru Xie, Ying Jia, Mianran Chao
A facile oxychlorination of various alkynes and alkenes with tBuOCl as an alternative chlorine source and H2O as a green oxygen source.
The content of this RSS Feed (c) The Royal Society of Chemistry




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3-Halo-5,6-dihydro-4H-1,2-oxazine N-oxides as synthetic equivalents of unsaturated nitrile oxides in the [3 + 2]-cycloaddition with arynes: synthesis of substituted 3-vinyl-1,2-benzisoxazoles

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00391H, Communication
Alexander A. Lukoyanov, Svetlana A. Aksenova, Andrey A. Tabolin, Alexey Yu. Sukhorukov
3-Halo-1,2-oxazine N-oxide derivatives act as surrogates of vinyl nitrile oxides in tandem [3 + 2]-cycloaddition/[3 + 2]-cyclofragmentation with arynes leading to benzisoxazoles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of selective monosaccharide receptors via dynamic combinatorial chemistry

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00015C, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Miguel Alena-Rodriguez, Marcos Fernandez-Villamarin, Ignacio Alfonso, Paula M. Mendes
An effective workflow to discover selective saccharide receptors by combining dynamic combinatorial chemistry with isothermal titration calorimetry and NMR.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tab Discarding in Chrome: a Memory-Saving Experiment




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Tickets to safe flying

A list of the top Covid-19-compliant airlines




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Air India sale: Who will bag the Maharaja's crown?

Financial bid winner for sale of the State-owned airlines to be declared in three weeks; sources say it may take longer




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India ahead in tech to make airports safer

Airports are also keeping pace to ensure safe, touchless and seamless journeys




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Pick the rear seats to fly safe

Passengers who pick a seat near the tail of an aeroplane are more likely to survive a crash




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Thrust reversal in aircraft

It functions by directing the thrust produced by the plane’s jet engines forward, rather than backwards




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Will Akasa Air’s contra bet on Boeing 737 Max instead of Airbus pay off?

Rakesh Jhunjhunwala’s Akasa airline has gone against the tide, placing its bets on Boeing aircrafts; it now needs to carve out a niche for itself 




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Chicken gun test: Saving jets from bird strikes

According to ICAO, at least 34 bird strikes happen every day, causing around $1 billion worth damages every year




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Sarvam AI launches Sarvam 1 for Indic languages

The custom training corpus, Sarvam-2T comprised of 20 percent datasets in Hindi as well as English and programming languages so the AI model can perform multilingual tasks




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Microsoft Teams to launch threaded conversations, combined chats and channels features

The app has also added other changes in the interface so users can organise their chats better




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Amazon's improving retail sales boost third-quarter profit, revenue beats estimates

Like its tech peers, Amazon said it expected higher capital expenditures for the foreseeable future to help develop artificial intelligence software




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OpenAI CEO Sam Altman says next big AI model launch pushed due to compute challenges

Altman also said that the next update for DALL-E was still in the works with no release date yet




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Indonesia bans sales of Google phones days after blocking Apple's iPhone 16

Indonesia said it has banned sales of smartphones made by Alphabet's Google due to rules requiring the use of locally manufactured components




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Perplexity AI CEO says “still haven’t gotten” a green card amid immigration debate ahead of U.S. Presidential Election 2024

Srinivas went on to work with OpenAI for a year before co-founding Perplexity AI in 2022




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High cataract rate among elderly in Mucherla, Meerkhanpet of Rangareddy district, says survey

HHF’s screening of 200 patients in Mucherla and Meerkhanpet found that 21% had senile cataracts, 18% had immature cataracts, and 15% had refractive errors




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WHO says ‘intense bombardment’ halts Gaza polio vaccinations

The U.N. health body said it had been “compelled to postpone” the bid to give 119,279 children in northern Gaza a second vaccine dose due to the escalating violence




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Why did the Centre sanction a 50% hike in prices of commonly-used drugs?

According to the government the recent 50% hike in prices of eight drugs was sanctioned keeping in mind the larger public interest and to ensure continued availability of drugs




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Drugs regulator finds 49 samples not of standard quality, manufacturers asked to withdraw their products

Four spurious drugs were also found and action has been initiated against the makers, the DCGI said




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OpenAI’s Whisper transcription tool used in hospitals invents things no one ever said, researchers claim

Whisper is a popular transcription tool powered by artificial intelligence, but it has a major flaw




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Lifestyle changes a major cause for stroke, say doctors

Speaking at a public awareness meeting organised at GRH on the occasion of World Stroke Day on Tuesday, Dr. Murugan, attributed these negative factors to a sedentary lifestyle because of the youth’s job nature and location




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Telemedicine in India: is the government’s eSanjeevani platform living up to its potential?

While the eSanjeevani numbers are impressive, doctors and experts point out that unless a number of systemic issues -- including low doctor numbers on the platform are fixed -- telemedicine in the country will not be able to move past infancy




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Tiruchi man with mpox symptoms: Sample has returned negative, says Tamil Nadu Health Minister

The man, who had returned from Sharjah on October 31, was found to have fever during screening on arriving at the Tiruchi airport.




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WHO says strike on Gaza polio vaccination centre wounds four children

The World Health Organization’s chief Tedros Adhanom Ghebreyesus said the health centre was “in an area where a humanitarian pause was agreed to allow vaccination to proceed” and that the attack could put off parents of children needing a second vaccine




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Stop abuse of patent monopolies in rare diseases, say patient representatives and treatment activists 

They seek urgent intervention by government, courts, and lawmakers into the issue  




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Lassa fever: Understanding the risk, response and global threat

The Lassa virus causes Lassa fever, a zoonotic disease; humans usually contract the virus through contact with food or items contaminated by the the Mastomys rat’s urine or faeces.




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National Task Force files interim report on safety measures for hospital staff

NTF report has suggested short term, medium, and long term measures to protect doctors and medical staff in their workplaces.




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Can mid-level healthcare providers compensate for physician shortages in rural India?

To make up for doctor shortages, several countries around the world have introduced a cadre of MLHPs into their health systems; however, in India, mainstreaming of MLHPs has time and again been met with resistance from organised medicine 





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'Ranbir said, 'Yaar, what a shot you gave!''

'Ranbir helped me a lot with emotions and dialogues. As an actor, he makes us very secure.''He guides us with his experiences. He makes the work really, really easy and wonderful for his co-stars.'




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'Prasanth wanted Yash to play Hanuman'

'Since God was being shown in live action on such a large scale, Prasanth was initially sceptical about going with an animated character.'




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WATCH Seepi Sing Sabki Baaratein Aayi 2!

'There was this music director who approached me for a song. He called me to his house for practice.''I took my mother with me and I felt he did not like that.''It took me a while to gauge his intentions.''That really scarred me.'




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Aditi Sings Ang Laga De, Noodle Sa Dil!

'There must have been some wonderful genetic disorder due to which I was attracted towards filmi songs.'





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'Bhansali teaches you without a danda'

'When you walk on to a Sanjay Leela Bhansali set, it is complete surrender. You have to become a sponge.'





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'Sometimes Sanjay Sir Would Be On Fire'

'Before every scene, Sanjay Leela Bhansali would play two or three songs over and over again, especially when Sharmin and I would shoot, because it invoked his emotion. One of the songs was from The Last Samurai. Everything is in rhythm for him. If he doesn't have that rhythm in place, then something is off.'




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'Stars Don't Make A Movie But Vice-Versa'

'Stars have made stacks of wealth at the cost of the rest of the film industry.'




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'Can't Say Bigg Boss Promoting Polygamy'

'Ranvir will run out of steam pretty soon.''The way he is reacting or rather, overreacting to things, I am sure he will be exhausted soon.''You need to chill at times to play a game like Bigg Boss.'





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'People Said A Lot Of Things Against Me'

'I believe one should never disrespect their elders but if the person does not know how to talk to people, then I am sorry, I cannot take it.'




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'We Love Our Country And Want To Save It'

'I have been through a lot of auditions and the first thing we are told is that there will be intimate scenes and we have to be okay with it.'Luckily, there is no bold content in Commander Karan Saxena.'





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'Salman Has A Soft Corner For His Dad'

'Salman wanted to do the interview properly. That's why he was nervous, you know, that dad should be happy.'




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'There Is A Fear Of Disappearing'

'God can you get work, but once you get it, you have to do it with honesty and put your 100 percent into it.'




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Shahana's Santosh Is UK's Oscar Choice!

'I'm there in every frame of this film.''The film is named after the character that I play.''It's about a feeling like you are capable of shouldering a film entirely on your own, which is a belief that I may not have in myself always.'