qua Knots made in a weird quantum fluid can last forever By www.newscientist.com Published On :: Wed, 06 Nov 2024 20:15:51 +0000 Shapes created by vortices in water often fall apart, but an odd quantum fluid made from ultracold atoms could support vortex knots that never lose their knottiness Full Article
qua Quantum Rubik's cube has infinite patterns but is still solvable By www.newscientist.com Published On :: Fri, 08 Nov 2024 15:30:22 +0000 Allowing for moves that create quantum superpositions makes a quantum version of a Rubik’s cube incredibly complex, but not impossible to solve Full Article
qua Quality of Pain Counts as Much as Intensity, Researchers Say By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Quality of Pain Counts as Much as Intensity, Researchers SayCategory: Health NewsCreated: 8/26/2010 4:10:00 PMLast Editorial Review: 8/27/2010 12:00:00 AM Full Article
qua 2 Common Blood Pressure Meds Fare Equally in Preventing Heart Woes By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: 2 Common Blood Pressure Meds Fare Equally in Preventing Heart WoesCategory: Health NewsCreated: 8/27/2012 6:05:00 PMLast Editorial Review: 8/28/2012 12:00:00 AM Full Article
qua Race May Affect Quality of Prostate Cancer Surgical Care By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Race May Affect Quality of Prostate Cancer Surgical CareCategory: Health NewsCreated: 8/28/2012 6:05:00 PMLast Editorial Review: 8/29/2012 12:00:00 AM Full Article
qua Heart Attacks, Strokes Jumped After Japan Earthquake, Study Finds By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Heart Attacks, Strokes Jumped After Japan Earthquake, Study FindsCategory: Health NewsCreated: 8/30/2012 2:05:00 PMLast Editorial Review: 8/31/2012 12:00:00 AM Full Article
qua After Heart Attack, Quitting Smoking Boosts Mental Health, Quality of Life By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: After Heart Attack, Quitting Smoking Boosts Mental Health, Quality of LifeCategory: Health NewsCreated: 8/25/2015 12:00:00 AMLast Editorial Review: 8/26/2015 12:00:00 AM Full Article
qua How to Keep Your Kids Trim Through Quarantine By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: How to Keep Your Kids Trim Through QuarantineCategory: Health NewsCreated: 8/25/2020 12:00:00 AMLast Editorial Review: 8/26/2020 12:00:00 AM Full Article
qua Banded Squats: Benefits and 11 Ways to Do Them By www.medicinenet.com Published On :: Mon, 8 Aug 2022 00:00:00 PDT Title: Banded Squats: Benefits and 11 Ways to Do ThemCategory: Health and LivingCreated: 8/8/2022 12:00:00 AMLast Editorial Review: 8/8/2022 12:00:00 AM Full Article
qua Only One Quarter of Family Physicians Are Very Satisfied with Their Electronic Health Records Platform By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Two decades into the era of Electronic Health Records (EHRs), the promise of streamlining clinical care, reducing burden, and improving patient outcomes has yet to be realized. A cross-sectional family physician census conducted by the American Board of Family Medicine in 2022 and 2023 included self-reported physician EHR satisfaction. Of the nearly 10,000 responding family physicians, only one-in-four (26.2%) report being very satisfied and one-in-three (33.8%) were not satisfied. These low levels of satisfaction point to the need for greater transparency in the marketplace and pressure to increase user-centric EHR design. Full Article
qua A Qualitative Analysis of a Primary Care Medical-Legal Partnership: Impact, Barriers, and Facilitators By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Certain health-related risk factors require legal interventions. Medical-legal partnerships (MLPs) are collaborations between clinics and lawyers that address these health-harming legal needs (HHLNs) and have been shown to improve health and reduce utilization. Objective: The objective of this study is to explore the impact, barriers, and facilitators of MLP implementation in primary care clinics. Methods: A qualitative design using a semistructured interview assessed the perceived impact, barriers, and facilitators of an MLP, among clinicians, clinic and MLP staff, and clinic patients. Open AI software (otter.ai) was used to transcribe interviews, and NVivo was used to code the data. Braun & Clarke’s framework was used to identify themes and subthemes. Results: Sixteen (n = 16) participants were included in this study. Most respondents were women (81%) and white (56%). Four respondents were clinic staff, and 4 were MLP staff while 8 were clinic patients. Several primary themes emerged including: Patients experienced legal issues that were pernicious, pervasive, and complex; through trusting relationships, the MLP was able to improve health and resolve legal issues, for some; mistrust, communication gaps, and inconsistent staffing limited the impact of the MLP; and, the MLP identified coordination and communication strategies to enhance trust and amplify its impact. Conclusion: HHLNs can have a significant, negative impact on the physical and mental health of patients. Respondents perceived that MLPs improved health and resolved these needs, for some. Despite perceived successes, integration between the clinical and legal organizations was elusive. Full Article
qua Physician Satisfaction Should Be the Measure of Electronic Health Record Quality for the Nation By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Full Article
qua The Challenge of Implementing Race-Neutral PFT Reference Equations By rc.rcjournal.com Published On :: 2024-10-25T05:44:13-07:00 Full Article
qua Quantitative Computed Tomography and Response to Pronation in COVID-19 ARDS By rc.rcjournal.com Published On :: 2024-10-25T05:44:12-07:00 BACKGROUND:The use of prone position (PP) has been widespread during the COVID-19 pandemic. Whereas it has demonstrated benefits, including improved oxygenation and lung aeration, the factors influencing the response in terms of gas exchange to PP remain unclear. In particular, the association between baseline quantitative computed tomography (CT) scan results and gas exchange response to PP in invasively ventilated subjects with COVID-19 ARDS is unknown. The present study aimed to compare baseline quantitative CT results between subjects responding to PP in terms of oxygenation or CO2 clearance and those who did not.METHODS:This was a single-center, retrospective observational study including critically ill, invasively ventilated subjects with COVID-19–related ARDS admitted to the ICUs of Niguarda Hospital between March 2020–November 2021. Blood gas samples were collected before and after PP. Subjects in whom the PaO2/FIO2 increase was ≥ 20 mm Hg after PP were defined as oxygen responders. CO2 responders were defined when the ventilatory ratio (VR) decreased during PP. Automated quantitative CT analyses were performed to obtain tissue mass and density of the lungs.RESULTS:One hundred twenty-five subjects were enrolled, of which 116 (93%) were O2 responders and 51 (41%) CO2 responders. No difference in quantitative CT characteristics and oxygen were observed between responders and non-responders (tissue mass 1,532 ± 396 g vs 1,654 ± 304 g, P = .28; density −544 ± 109 HU vs −562 ± 58 HU P = .42). Similar findings were observed when dividing the population according to CO2 response (tissue mass 1,551 ± 412 g vs 1,534 ± 377 g, P = .89; density −545 ± 123 HU vs −546 ± 94 HU, P = .99).CONCLUSIONS:Most subjects with COVID-19–related ARDS improved their oxygenation at the first pronation cycle. The study suggests that baseline quantitative CT scan data were not associated with the response to PP in oxygenation or CO2 in mechanically ventilated subjects with COVID-19–related ARDS. Full Article
qua Quantitatively Predicting Effects of Exercise on Pharmacokinetics of Drugs Using a Physiologically Based Pharmacokinetic Model [Articles] By dmd.aspetjournals.org Published On :: 2024-10-16T09:02:03-07:00 Exercise significantly alters human physiological functions, such as increasing cardiac output and muscle blood flow and decreasing glomerular filtration rate (GFR) and liver blood flow, thereby altering the absorption, distribution, metabolism, and excretion of drugs. In this study, we aimed to establish a database of human physiological parameters during exercise and to construct equations for the relationship between changes in each physiological parameter and exercise intensity, including cardiac output, organ blood flow (e.g., muscle blood flow and kidney blood flow), oxygen uptake, plasma pH and GFR, etc. The polynomial equation P = aiHRi was used for illustrating the relationship between the physiological parameters (P) and heart rate (HR), which served as an index of exercise intensity. The pharmacokinetics of midazolam, quinidine, digoxin, and lidocaine during exercise were predicted by a whole-body physiologically based pharmacokinetic (WB-PBPK) model and the developed database of physiological parameters following administration to 100 virtual subjects. The WB-PBPK model simulation results showed that most of the observed plasma drug concentrations fell within the 5th–95th percentiles of the simulations, and the estimated peak concentrations (Cmax) and area under the curve (AUC) of drugs were also within 0.5–2.0 folds of observations. Sensitivity analysis showed that exercise intensity, exercise duration, medication time, and alterations in physiological parameters significantly affected drug pharmacokinetics and the net effect depending on drug characteristics and exercise conditions. In conclusion, the pharmacokinetics of drugs during exercise could be quantitatively predicted using the developed WB-PBPK model and database of physiological parameters. SIGNIFICANCE STATEMENT This study simulated real-time changes of human physiological parameters during exercise in the WB-PBPK model and comprehensively investigated pharmacokinetic changes during exercise following oral and intravenous administration. Furthermore, the factors affecting pharmacokinetics during exercise were also revealed. Full Article
qua Quantitative Proteomics for Translational Pharmacology and Precision Medicine: State of The Art and Future Outlook [Minireview] By dmd.aspetjournals.org Published On :: 2024-10-16T09:02:03-07:00 Over the past 20 years, quantitative proteomics has contributed a wealth of protein expression data, which are currently used for a variety of systems pharmacology applications, as a complement or a surrogate for activity of the corresponding proteins. A symposium at the 25th North American International Society for the Study of Xenobiotics meeting, in Boston, in September 2023, was held to explore current and emerging applications of quantitative proteomics in translational pharmacology and strategies for improved integration into model-informed drug development based on practical experience of each of the presenters. A summary of the talks and discussions is presented in this perspective alongside future outlook that was outlined for future meetings. SIGNIFICANCE STATEMENT This perspective explores current and emerging applications of quantitative proteomics in translational pharmacology and precision medicine and outlines the outlook for improved integration into model-informed drug development. Full Article
qua National Politics’ Role in Developing Primary Health Care Policy for Maternal Health in Papua New Guinea: A Qualitative Document Analysis By ghspjournal.org Published On :: 2024-10-29T12:28:39-07:00 ABSTRACTPolitics is one of the critical factors that influence health policy agendas. However, scholarly efforts, especially in low- and middle-income countries, rarely focus on how politics influence health policy agenda-setting. We conducted a qualitative document review to examine the factors that led to developing the free primary health care policy for maternal health in Papua New Guinea. We also discuss mechanisms through which national politics, as an overriding factor, influenced the development of the policy. The review draws on Kingdon’s multiple-stream model for agenda-setting and incorporates theoretical insights from Fox and Reich’s framework for analyzing the politics of health reform for universal health coverage in low- and middle-income countries. Full Article
qua [18F]AlF-NOTA-FAPI-04 PET/CT for Predicting Pathologic Response of Resectable Esophageal Squamous Cell Carcinoma to Neoadjuvant Camrelizumab and Chemotherapy: A Phase II Clinical Trial By jnm.snmjournals.org Published On :: 2024-11-01T04:25:31-07:00 This single-center, single-arm, phase II trial (ChiCTR2100050057) investigated the ability of 18F-labeled fibroblast activation protein inhibitor ([18F]AlF-NOTA-FAPI-04, denoted as 18F-FAPI) PET/CT to predict the response to neoadjuvant camrelizumab plus chemotherapy (nCC) in locally advanced esophageal squamous cell carcinoma (LA-ESCC). Methods: This study included 32 newly diagnosed LA-ESCC participants who underwent 18F-FAPI PET/CT at baseline, of whom 23 also underwent scanning after 2 cycles of nCC. The participants underwent surgery after 2 cycles of nCC. Recorded PET parameters included maximum, peak, and mean SUVs and tumor-to-background ratios (TBRs), metabolic tumor volume, and total lesion FAP expression. PET parameters were compared between patient groups with good and poor pathologic responses, and the predictive performance for treatment response was analyzed. Results: The good and poor response groups each included 16 participants (16/32, 50.0%). On 18F-FAPI PET/CT, the posttreatment SUVs were significantly lower in good responders than in poor responders, whereas the changes in SUVs with treatment were significantly higher (all P < 0.05). SUVmax (area under the curve [AUC], 0.87; P = 0.0026), SUVpeak (AUC, 0.89; P = 0.0017), SUVmean (AUC, 0.88; P = 0.0021), TBRmax (AUC, 0.86; P = 0.0031), and TBRmean (AUC, 0.88; P = 0.0021) after nCC were significant predictors of pathologic response to nCC, with sensitivities of 63.64%–81.82% and specificities of 83.33%–100%. Changes in SUVmax (AUC, 0.81; P = 0.0116), SUVpeak (AUC, 0.82; P = 0.0097), SUVmean (AUC, 0.81; P = 0.0116), and TBRmean (AUC, 0.74; P = 0.0489) also were significant predictors of the pathologic response to nCC, with sensitivities and specificities in similar ranges. Conclusion: 18F-FAPI PET/CT parameters after treatment and their changes from baseline can predict the pathologic response to nCC in LA-ESCC participants. Full Article
qua Neuroimaging Correlates with Clinical Severity in Wilson Disease: A Multiparametric Quantitative Brain MRI [RESEARCH] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 BACKGROUND AND PURPOSE: Previous studies have reported metal accumulation and microstructure changes in deep gray nuclei (DGN) in Wilson disease (WD). However, there are limited studies that investigate whether there is metal accumulation and microstructure changes in DGN of patients with WD with normal-appearing routine MRI. This study aimed to evaluate multiparametric changes in DGN of WD and whether the findings correlate with clinical severity in patients with WD. MATERIALS AND METHODS: The study enrolled 28 patients with WD (19 with neurologic symptoms) and 25 controls. Fractional anisotropy (FA), mean diffusivity (MD), and magnetic susceptibility in globus pallidus, pontine tegmentum, dentate nucleus, red nucleus, head of caudate nucleus, putamen, substantia nigra, and thalamus were extracted. Correlations between imaging data and the Unified Wilson’s Disease Rating Scale (UWDRS) neurologic subitems were explored. RESULTS: FA, MD, and susceptibility values were higher in multiple DGN of patients with WD than controls (P < .05). Patients with WD without abnormal signals in DGN on routine MRI also had higher FA, MD, and susceptibility values than controls (P < .017). We found that UWDRS neurologic subscores correlated with FA and susceptibility values of DGN (P < .05). In addition, we also found that FA and susceptibility values in specific structures correlated with specific neurologic symptoms of WD (ie, tremor, parkinsonism, dysarthria, dystonia, and ataxia) (P < .05). CONCLUSIONS: Patients with WD have increased FA, MD, and susceptibility values even before the lesion is morphologically apparent on routine MRI. The increased FA and susceptibility values correlate with clinical severity of WD. Full Article
qua Deep Learning-Based Reconstruction of 3D T1 SPACE Vessel Wall Imaging Provides Improved Image Quality with Reduced Scan Times: A Preliminary Study [ARTIFICIAL INTELLIGENCE] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 BACKGROUND AND PURPOSE: Intracranial vessel wall imaging is technically challenging to implement, given the simultaneous requirements of high spatial resolution, excellent blood and CSF signal suppression, and clinically acceptable gradient times. Herein, we present our preliminary findings on the evaluation of a deep learning–optimized sequence using T1-weighted imaging. MATERIALS AND METHODS: Clinical and optimized deep learning–based image reconstruction T1 3D Sampling Perfection with Application optimized Contrast using different flip angle Evolution (SPACE) were evaluated, comparing noncontrast sequences in 10 healthy controls and postcontrast sequences in 5 consecutive patients. Images were reviewed on a Likert-like scale by 4 fellowship-trained neuroradiologists. Scores (range, 1–4) were separately assigned for 11 vessel segments in terms of vessel wall and lumen delineation. Additionally, images were evaluated in terms of overall background noise, image sharpness, and homogeneous CSF signal. Segment-wise scores were compared using paired samples t tests. RESULTS: The scan time for the clinical and deep learning–based image reconstruction sequences were 7:26 minutes and 5:23 minutes respectively. Deep learning–based image reconstruction images showed consistently higher wall signal and lumen visualization scores, with the differences being statistically significant in most vessel segments on both pre- and postcontrast images. Deep learning–based image reconstruction had lower background noise, higher image sharpness, and uniform CSF signal. Depiction of intracranial pathologies was better or similar on the deep learning–based image reconstruction. CONCLUSIONS: Our preliminary findings suggest that deep learning–based image reconstruction–optimized intracranial vessel wall imaging sequences may be helpful in achieving shorter gradient times with improved vessel wall visualization and overall image quality. These improvements may help with wider adoption of intracranial vessel wall imaging in clinical practice and should be further validated on a larger cohort. Full Article
qua Geographic inequalities in need and provision of social prescribing link workers a retrospective study in primary care By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 BackgroundLong-term health conditions are major challenges for care systems. Social prescribing link workers have been introduced via primary care networks (PCNs) across England since 2019 to address the wider determinants of health by connecting individuals to activities, groups, or services within their local community.AimTo assess whether the rollout of social prescribing link workers was in areas with the highest need.Design and settingA retrospective study of social prescribing link workers in England from 2019 to 2023.MethodWorkforce, population, survey, and area-level data at the PCN-level from April 2020 to October 2023 were combined. Population need before the rollout of link workers was measured using reported lack of support from local services in the 2019 General Practice Patient Survey. To assess if rollout reflected need, linear regression was used to relate provision of link workers (measured by full-time equivalent [FTE] per 10 000 patients) in each quarter to population need for support.ResultsPopulations in urban, more deprived areas and with higher proportions of people from minority ethnic groups had the highest reported lack of support. Geographically these were in the North West and London. Initially, there was no association between need and provision; then from July 2022, this became negative and significant. By October 2023, a 10-percentage point higher need for support was associated with a 0.035 (95% confidence interval = −0.634 to −0.066) lower FTE per 10 000 patients.ConclusionRollout of link workers has not been sufficiently targeted at areas with the highest need. Future deployments should be targeted at those areas. Full Article
qua Prescribing benzodiazepines in young adults with anxiety: a qualitative study of GP perspectives By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 BackgroundIncident benzodiazepine prescriptions in primary care for anxiety decreased between 2003 and 2018. However, from 2008, incident prescribing of benzodiazepines for anxiety increased among those aged 18–34 years. There are increasing concerns around prescribing of benzodiazepines. Further, although guidelines state benzodiazepines should only be prescribed short term, in 2017, 44% of incident prescriptions were prescribed for longer than the recommended duration of 2–4 weeks.AimTo understand when and why GPs prescribe benzodiazepines for anxiety in young adults.Design and settingA qualitative study was undertaken using in-depth interviews with 17 GPs from 10 general practices in South West England.MethodInterviews were conducted by telephone or videocall. A topic guide was used to ensure consistency across interviews. Interviews were audio-recorded, transcribed verbatim, and data analysed using reflexive thematic analysis.ResultsGPs described caution in prescribing benzodiazepines for anxiety in young adults, but thought they had an important role in acute situations. GPs described caution in prescribing duration, but some thought longer-term prescriptions could be appropriate. In light of these views, some GPs questioned whether primary care needs to revisit how clinicians are using benzodiazepines. GPs perceived that some young adults requested benzodiazepines and suggested this might be because they wanted quick symptom relief. GPs noted that refusing to prescribe felt uncomfortable and that the number of young adults presenting to general practice, already dependent on benzodiazepines, had increased.ConclusionPatient-driven factors for prescribing benzodiazepines suggest there are current unmet treatment needs among young adults with anxiety. Given increases in prescribing in this age group, it may be timely to revisit the role of benzodiazepines in the management of people with anxiety in primary care. Full Article
qua GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 BackgroundBetween 2003 and 2018, incident prescriptions of beta-blockers for anxiety increased substantially, particularly for young adults. National Institute for Health and Care Excellence guidance for anxiety does not recommend beta-blockers, probably due to a lack of evidence to support such use. Recent reports have highlighted the potential risks of beta-blockers.AimTo understand when and why GPs prescribe beta-blockers for people with anxiety.Design and settingIn-depth interviews with 17 GPs in Bristol and the surrounding areas.MethodInterviews were held by telephone or video call. A topic guide was used to ensure consistency across interviews. Interviews were audio-recorded, transcribed verbatim, and analysed thematically.ResultsMany GPs viewed beta-blockers as ‘low risk’, particularly for young adults. Some GPs viewed beta-blockers as an alternative to benzodiazepines, acting quickly and not leading to dependence. GPs reflected that some patients appeared to want an ‘immediate fix’ to their symptoms, which GPs thought beta-blockers could potentially offer. This is salient in light of substantial waiting lists for talking therapies and delays in antidepressants taking effect. GPs described how some patients seemed more willing to try beta-blockers than antidepressants, as patients did not perceive them as ‘mental health drugs’ and therefore viewed them as potentially more acceptable and less stigmatising. Further, GPs viewed beta-blockers as ‘patient-led’, with patients managing their own dose and frequency, without GP input.ConclusionMany GPs believe that beta-blockers have a role to play in the management of anxiety. Given recent increases in the prescribing of these drugs in primary care, there is a need to assess their safety and effectiveness as a treatment for people with anxiety disorders. Full Article
qua Collaborative discussions between GPs and pharmacists to optimise patient medication: a qualitative study within a UK primary care clinical trial By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 BackgroundThere has been significant investment in pharmacists working in UK general practice to improve the effective and safe use of medicines. However, evidence of how to optimise collaboration between GPs and pharmacists in the context of polypharmacy (multiple medication) is lacking.AimTo explore GP and pharmacist views and experiences of in-person, interprofessional collaborative discussions (IPCDs) as part of a complex intervention to optimise medication use for patients with polypharmacy in general practice.Design and settingA mixed-method process evaluation embedded within the Improving Medicines use in People with Polypharmacy in Primary Care (IMPPP) trial conducted in Bristol and the West Midlands, between February 2021 and September 2023.MethodAudio-recordings of IPCDs between GPs and pharmacists, along with individual semi-structured interviews to explore their reflections on these discussions, were used. All recordings were transcribed verbatim and analysed thematically.ResultsA total of 14 practices took part in the process evaluation from February 2022 to September 2023; 17 IPCD meetings were audio-recorded, discussing 30 patients (range 1–6 patients per meeting). In all, six GPs and 13 pharmacists were interviewed. The IPCD was highly valued by GPs and pharmacists who described benefits, including: strengthening their working relationship; gaining in confidence to manage more complex patients; and learning from each other. It was often challenging, however, to find time for the IPCDs.ConclusionThe model of IPCD used in this study provided protected time for GPs and pharmacists to work together to deliver whole-patient care, with both professions finding this beneficial. Protected time for interprofessional liaison and collaboration, and structured interventions may facilitate improved patient care. Full Article
qua General practice should tackle healthcare inequalities but not health inequalities By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 Full Article
qua Primary care health professionals’ approach to clinical coding: a qualitative interview study By bjgp.org Published On :: 2024-10-31T16:05:26-07:00 Full Article
qua Digital Innovation to Grow Quality Care Through an Interprofessional Care Team (DIG IT) Among Underserved Patients With Hypertension [Original Research] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 PURPOSE The impact of digital health on medically underserved patients is unclear. This study aimed to determine the early impact of a digital innovation to grow quality care through an interprofessional care team (DIG IT) on the blood pressure (BP) and 10-year atherosclerotic cardiovascular disease (ASCVD) risk score of medically underserved patients. METHODS This was a 3-month, prospective intervention study that included patients aged 40 years or more with BP of 140/90 mmHg or higher who received care from DIG IT from August through December 2021. Sociodemographic and clinical outcomes of DIG IT were compared with historical controls (controls) whose data were randomly extracted by the University of California Data Warehouse and matched 1:1 based on age, ethnicity, and baseline BP of the DIG IT arm. Multiple linear regression was performed to adjust for potential confounding factors. RESULTS A total of 140 patients (70 DIG IT, 70 controls) were included. Both arms were similar with an average age (SD) of 62.8 (9.7) years. The population was dominated by Latinx (79.3%) persons, with baseline mean BP of 163/81 mmHg, and mean ASCVD risk score of 23.9%. The mean (SD) reduction in systolic BP at 3 months in the DIG IT arm was twice that of the controls (30.8 [17.3] mmHg vs 15.2 [21.2] mmHg; P <.001). The mean (SD) ASCVD risk score reduction in the DIG IT arm was also twice that of the controls (6.4% [7.4%] vs 3.1% [5.1%]; P = .003). CONCLUSIONS The DIG IT was more effective than controls (receiving usual care). Twofold improvement in the BP readings and ASCVD scores in medically underserved patients were achieved with DIG IT. Full Article
qua Challenges in Receiving Care for Long COVID: A Qualitative Interview Study Among Primary Care Patients About Expectations and Experiences [Original Research] By www.annfammed.org Published On :: 2024-09-23T14:00:14-07:00 BACKGROUND For many patients with post–COVID-19 condition (long COVID), primary care is the first point of interaction with the health care system. In principle, primary care is well situated to manage long COVID. Beyond expressions of disempowerment, however, the patient’s perspective regarding the quality of long COVID care is lacking. Therefore, this study aimed to analyze the expectations and experiences of primary care patients seeking treatment for long COVID. METHODS A phenomenological approach guided this analysis. Using purposive sampling, we conducted semistructured interviews with English-speaking, adult primary care patients describing symptoms of long COVID. We deidentified and transcribed the recorded interviews. Transcripts were analyzed using inductive qualitative content analysis. RESULTS This article reports results from 19 interviews (53% female, mean age = 54 years). Patients expected their primary care practitioners (PCPs) to be knowledgeable about long COVID, attentive to their individual condition, and to engage in collaborative processes for treatment. Patients described 2 areas of experiences. First, interactions with clinicians were perceived as positive when clinicians were honest and validating, and negative when patients felt dismissed or discouraged. Second, patients described challenges navigating the fragmented US health care system when coordinating care, treatment and testing, and payment. CONCLUSION Primary care patients’ experiences seeking care for long COVID are incongruent with their expectations. Patients must overcome barriers at each level of the health care system and are frustrated by the constant challenges. PCPs and other health care professionals might increase congruence with expectations and experiences through listening, validating, and advocating for patients with long COVID. Annals Early Access article Full Article
qua Column: For black athletes, wealth doesn’t equal freedom By www.pbs.org Published On :: Wed, 18 Oct 2017 17:19:03 +0000 Jacksonville Jaguars NFL players kneel before the national anthem before their game against the New York Jets on Oct. 1, 2017. Photo by REUTERS/Eduardo Munoz In America, there’s a significant kind of public insistence that one’s “freedom” is fundamentally tied to one’s wealth. Much of the country views America through an aspirational and transformative lens, a colorblind and bias-free utopia, wherein wealth conveys equality and acts as a panacea for social and racial ills. Once an individual achieves massive financial success, or so the message goes, he or she will “transcend” the scourge of economic and racial inequality, truly becoming “free.” Working in parallel with this reverence for this colorblind version of the “American Dream” is the belief that economic privilege mandates patriotic gratitude. Across industries and disciplines, Americans are told to love their nation uncritically, be thankful that they are exceptional enough to live in a country that allows citizens the opportunity to reach astronomical heights of economic prosperity. For the nation’s black citizens, there’s often an additional racialized presumption lurking under the surface of these concepts: the notion that black success and wealth demands public silence on systemic issues of inequality and oppression. One’s economic privilege is a lousy barrier against discrimination and oppression. These are durable and fragile ideologies that prop up the concept of the American Dream – durable because they are encoded in the very fabric of American culture (most Americans, including African Americans, have readily embraced these ideologies as assumed facts); yet fragile because it’s all too easy to see that one’s economic privilege is a lousy barrier against both individual and systemic discrimination and oppression. Consequently, black people have also been among the most vocal challengers of these ideologies, as we’ve seen most recently with the Colin Kaepernick and the NFL #TakeAKnee demonstrations. In a show of solidary with the free agent quarterback, professional football players – the vast majority of whom are black – have been kneeling during the National Anthem as a means of protesting racial injustice and police brutality. WATCH: NFL players team up in defiance and solidarity Over the past few weeks, the president of the United States has brought renewed attention to the inherent tensions that define the ideologies of the “American Dream” through his repeated public criticisms of these kneeling NFL players. “If a player wants the privilege of making millions of dollars in the NFL, or other leagues,” Trump recently tweeted, he or she should not be allowed to kneel. Labeling the protestors actions “disrespectful” to the country, flag and anthem, President Donald Trump has called for players to be fired, encouraged a boycott of the NFL, insisted that the league pass a rule mandating that players stand for the anthem and derided the protestors as “sons of bitches.” In a dramatic ploy more befitting of a scripted reality television show, the president gloated that he had instructed Vice President Mike Pence to walk out of an Indianapolis Colts game the moment any player kneeled. This was an orchestrated show of power and outrage, designed to send a flamboyant political message given that Trump and Pence knew in advance that on that particular day, the Colts were playing the San Francisco 49ers – the team that currently has the most protestors. The NFL’s announcement this week that the league has no plans to penalize protesting players is the most recent event to provoke the president’s fury; taking to social media during the early morning, he once again equated kneeling with “total disrespect” for our country. As many have pointed out, the president’s moralizing outrage toward the NFL players is selective and deeply flawed – his apparent patriotic loyalty hasn’t stopped the billionaire politician from criticizing the removal of Confederate statues, or attacking a Gold Star family, or mocking Sen. John McCain’s military service. By aggressively targeting the NFL players, Trump believes that he is “winning the cultural war,” having made black “millionaire sport athletes his new [Hillary Clinton].” The NFL players and their defenders have repeatedly stated that the protests are intended to highlight racial inequality and oppression. They’ve also explained that their decision to kneel emerged from a desire to protest peacefully and respectfully after a sustained conversation with military veterans. Trump has chosen to ignore these rationales and the structural issues of inequality that motivate the protests and instead, advance a narrative exclusively concerned with overt displays of American patriotism and the “privilege” of the NFL players. As one of president’s advisors explained, by aggressively targeting the NFL players, Trump believes that he is “winning the cultural war,” having made black “millionaire sport athletes his new [Hillary Clinton].” READ MORE: As ‘America’s sport,’ the NFL cannot escape politics It’s a cynical statement, revealing the president’s perception of the jingoism of his base of supporters who envision him as a crusader for American values and symbols. In casting the black protestors as the antithesis of all of this, Trump has marked the players as unpatriotic elites and enemies of the nation. For a president who has consistently fumbled his way through domestic and foreign policy since he was elected, a culture war between “hard-working” and “virtuous” working-class and middle-class white Americans and rich, ungrateful black football players is a welcome public distraction. Trump’s attacks on the NFL protestors are rooted in those competing tensions inherent to the American Dream: that wealth equals freedom; that economic privilege demands patriotic gratitude; and most importantly, that black people’s individual economic prosperity invalidates their concerns about systemic injustice and requires their silence on racial oppression. Among the protestors’ detractors, this has become a common line of attack, a means of disparaging the black NFL players’ activism by pointing to their apparent wealth. The fact that systemic racism is demonstrably real and that individual prosperity does not make one immune to racial discrimination appears to be lost on the protestors’ critics. Theirs is a grievance that suggests that black athletes should be grateful to live in this country; that racism can’t exist in America since black professional athletes are allowed to play and sign contracts for considerable sums of money; that black players owe the nation their silence since America “gave” them opportunity and access; that black athletes have no moral authority on issues of race and inequality because of their individual success; and that black athletes’ success was never theirs to earn, but instead, was given to them and can just as easily be taken away. Black athletes have long been hyper-aware of their peculiar place in American society: beloved for their talents, yet reviled the moment they use their public platform to protest. This culture war being waged over black athletes is not new. Black athletes – and entertainers – have long been hyper-aware of their peculiar place in American society as individuals beloved for their athletic and artistic talents, yet reviled the moment they use their public platform to protest systemic racial inequality. The parallels between the #TakeAKnee protests and the protests of Muhammad Ali or John Carlos and Tommie Smith are readily apparent; so too are there important similarities to the case of Paul Robeson. An outspoken civil rights activist, collegiate and professional football player, lawyer, opera singer and actor, Robeson had his passport revoked in 1950 because of his political activism and speech – actions that all but destroyed his career. The star athlete and entertainer, “who had exemplified American upward mobility” quickly “became public enemy number one” as institutions cancelled his concerts, the public called for his death and anti-Robeson mobs burned effigies of him. During a 1956 congressional hearing, the chairman of the House Committee on Un-American Activities beat a familiar refrain with Robeson, challenging the entertainer’s accusations of American racism and racial oppression. He saw no sign of prejudice, he argued, since Robeson was privileged, having gone to elite universities and playing collegiate and professional football. READ MORE: Poll: Americans divided on NFL protests Black athletes, even the silent ones, largely understand that their economic privilege doesn’t insulate them from the realities of racial discrimination. They also understand that their wealth and success is precarious and is often dependent not only upon their athletic performance, but also upon them remaining silent on issues of racial injustice, especially those that appear to question the “American Dream” or implicate the American public by association. It should come as no surprise then that Colin Kaepernick, whose protests turned him into a national pariah despite his on-the-field talents, has filed a grievance against the NFL, accusing the league and its teams of blackballing him because of his political beliefs. “Principled and peaceful political protest,” Kaepernick’s lawyers argued in a statement, “should not be punished and athletes should not be denied employment based on partisan political provocation by the Executive Branch of our government.” Whether the ostracized Kaepernick will win his grievance is unknown, but it is certainly telling that he and his lawyers have rooted their claims in contested definitions of freedom and the precarious economic privilege of outspoken NFL players. For the loudest and most vocal critics of black protestors, in particular, outspokenness is tantamount to treason, grounds for the harshest of punishments. Perhaps they would benefit from a close reading of James Baldwin, who once argued: “I love America more than any other country in this world, and, exactly for this reason, I insist on the right to criticize her perpetually.” The post Column: For black athletes, wealth doesn’t equal freedom appeared first on PBS NewsHour. Full Article nfl race Race Matters racial injustice Sports wealth
qua Venus could be rocked by thousands of quakes every year By www.newscientist.com Published On :: Wed, 18 Sep 2024 13:00:29 +0100 The second-closest planet to the sun is more geologically active than we thought and could have more than 17,000 venusquakes a year Full Article
qua Watch a robot peel a squash with human-like dexterity By www.newscientist.com Published On :: Fri, 26 Jul 2024 11:00:26 +0100 A robot can hold a squash, pumpkin or melon in one hand, while it is peeled by the other Full Article
qua Google breakthrough paves way for large-scale quantum computers By www.newscientist.com Published On :: Thu, 05 Sep 2024 12:04:05 +0100 Google has built a quantum computer that makes fewer errors as it is scaled up, and this may pave the way for machines that could solve useful real-world problems for the first time Full Article
qua Quantum computers teleport and store energy harvested from empty space By www.newscientist.com Published On :: Tue, 17 Sep 2024 23:18:48 +0100 A quantum computing protocol makes it possible to extract energy from seemingly empty space, teleport it to a new location, then store it for later use Full Article
qua Useful quantum computers are edging closer with recent milestones By www.newscientist.com Published On :: Mon, 30 Sep 2024 20:00:33 +0100 Google, Microsoft and others have taken big steps towards error-free devices, hinting that quantum computers that solve real problems aren’t far away Full Article
qua How 'quantum software developer' became a job that actually exists By www.newscientist.com Published On :: Wed, 16 Oct 2024 18:57:35 +0100 While quantum computers are still in their infancy, more and more people are training to become quantum software developers Full Article
qua Video Friday: Quadruped Ladder Climbing By spectrum.ieee.org Published On :: Fri, 04 Oct 2024 15:30:02 +0000 Video Friday is your weekly selection of awesome robotics videos, collected by your friends at IEEE Spectrum robotics. We also post a weekly calendar of upcoming robotics events for the next few months. Please send us your events for inclusion.IROS 2024: 14–18 October 2024, ABU DHABI, UAEICSR 2024: 23–26 October 2024, ODENSE, DENMARKCybathlon 2024: 25–27 October 2024, ZURICHHumanoids 2024: 22–24 November 2024, NANCY, FRANCEEnjoy today’s videos! Not even ladders can keep you safe from quadruped robots anymore.[ ETH Zürich Robot Systems Lab ]Introducing Azi (right), the new desktop robot from Engineered Arts Ltd. Azi and Ameca are having a little chat, demonstrating their wide range of expressive capabilities. Engineered Arts desktop robots feature 32 actuators, 27 for facial control alone, and 5 for the neck. They include AI conversational ability including GPT-4o support which makes them great robotic companions.[ Engineered Arts ]Quadruped robots that individual researchers can build by themselves are crucial for expanding the scope of research due to their high scalability and customizability. In this study, we develop a metal quadruped robot MEVIUS, that can be constructed and assembled using only materials ordered through e-commerce. We have considered the minimum set of components required for a quadruped robot, employing metal machining, sheet metal welding, and off-the-shelf components only.[ MEVIUS from JSK Robotics Laboratory ]Thanks Kento!Avian perching maneuvers are one of the most frequent and agile flight scenarios, where highly optimized flight trajectories, produced by rapid wing and tail morphing that generate high angular rates and accelerations, reduce kinetic energy at impact. Here, we use optimal control methods on an avian-inspired drone with morphing wing and tail to test a recent hypothesis derived from perching maneuver experiments of Harris’ hawks that birds minimize the distance flown at high angles of attack to dissipate kinetic energy before impact.[ EPFL Laboratory of Intelligent Systems ]The earliest signs of bearing failures are inaudible to you, but not to Spot . Introducing acoustic vibration sensing—Automate ultrasonic inspections of rotating equipment to keep your factory humming.The only thing I want to know is whether Spot is programmed to actually do that cute little tilt when using its acoustic sensors.[ Boston Dynamics ]Hear from Jonathan Hurst, our co-founder and Chief Robot Officer, why legs are ideally suited for Digit’s work.[ Agility Robotics ]I don’t think “IP67” really does this justice.[ ANYbotics ]This paper presents a teleportation system with floating robotic arms that traverse parallel cables to perform long-distance manipulation. The system benefits from the cable-based infrastructure, which is easy to set up and cost-effective with expandable workspace range.[ EPFL ]It seems to be just renderings for now, but here’s the next version of Fourier’s humanoid.[ Fourier ]Happy Oktoberfest from Dino Robotics![ Dino Robotics ]This paper introduces a learning-based low-level controller for quadcopters, which adaptively controls quadcopters with significant variations in mass, size, and actuator capabilities. Our approach leverages a combination of imitation learning and reinforcement learning, creating a fast-adapting and general control framework for quadcopters that eliminates the need for precise model estimation or manual tuning.[ HiPeR Lab ]Parkour poses a significant challenge for legged robots, requiring navigation through complex environments with agility and precision based on limited sensory inputs. In this work, we introduce a novel method for training end-to-end visual policies, from depth pixels to robot control commands, to achieve agile and safe quadruped locomotion.[ SoloParkour ] Full Article Agility robotics Anybotics Boston dynamics Robotics Robotics videos Video friday
qua Quadruped robot climbs ladders, creeps us out By www.foxnews.com Published On :: Sun, 03 Nov 2024 06:00:48 -0500 A Swiss-engineered robot can climb ladders, showing why it's at the cutting edge of autonomous robotic solutions for harsh industrial settings. Full Article 5f4b1dab-a341-5f42-9c4c-16faa938a30b fnc Fox News fox-news/tech fox-news/tech/topics/innovation fox-news/tech/technologies/robots fox-news/tech article
qua Junior India squad for Davis Cup, Fed Cup named By www.sport.co.uk Published On :: Tue, 13 Mar 2018 06:57:00 +0000 … Junior Asia/ Oceania Davis Cup and Fed Cup final qualifying event. The … players selected for the Junior Davis Cup include Dev V. Javia, Sandeep … Gogoi (reserve). The Junior Fed Cup team includes Anisha Kashyap, Bhakti … Junior Asia/ Oceania Junior Davis Cup will begin in Kuching, Malaysia …. Full Article
qua Alarming study shows quarter of elite rugby players have 'brain abnormalities' By www.telegraph.co.uk Published On :: Thu, 22 Jul 2021 06:00:00 GMT Full Article topics:things/dementia structure:sport structure:football structure:rugby-union storytype:standard
qua Spike in earthquakes at Washington volcano prompts more monitoring from scientists By www.foxnews.com Published On :: Mon, 07 Oct 2024 20:52:18 -0400 A spike in earthquakes at Mount Adams, a volcano in Washington state, prompted scientists to install additional monitoring instruments to assess the seismic activity. Full Article e89fee93-75e0-58bb-b9b1-bd7b9f04e20f fnc Fox News fox-news/us/us-regions/west/washington fox-news/us/disasters/earthquakes fox-news/science/planet-earth/geology fox-news/science fox-news/science article
qua Man arrested in NYC strangulation death of woman found outside Times Square hotel By www.foxnews.com Published On :: Tue, 12 Nov 2024 21:55:46 -0500 Authorities arrested a man accused of strangling a woman outside a Times Square hotel who later died from her injuries, police said Tuesday. Full Article d7d30f82-1959-5dbe-99be-c4c6d3d7b418 fnc Fox News fox-news/us/crime fox-news/us/new-york-city fox-news/us fox-news/us article
qua Air quality problems spur $200 million in funds to cut pollution at ports By arstechnica.com Published On :: Mon, 11 Nov 2024 14:27:15 +0000 Diesel equipment will be replaced with hydrogen- or electric-power gear. Full Article Policy Science carbon emissions climate change inflation reduction act pollution syndication
qua Dem Rep. Goldman: 'Shocked' Trump Picked an Unqualified Fox News Host to Head Pentagon By www.breitbart.com Published On :: Wed, 13 Nov 2024 02:34:50 +0000 Representative Dan Goldman (D-NY) said Tuesday on CNN's "OutFront" that he was "shocked" President-elect Donald Trump picked Fox News host Pete Hegseth as the next secretary of defense. The post Dem Rep. Goldman: ‘Shocked’ Trump Picked an Unqualified Fox News Host to Head Pentagon appeared first on Breitbart. Full Article Clips Politics CNN Department of Defense (DOD) Donald Trump Erin Burnett Pete Hegseth
qua Squadron 42’s new 2026 launch date will miss its original target by 11 years By arstechnica.com Published On :: Mon, 21 Oct 2024 15:52:44 +0000 RSI said single-player Star Citizen campaign was "feature complete" a year ago. Full Article Gaming
qua Canada captain Alphonso Davies to miss CONCACAF Nations League quarterfinal against Suriname By www.cbc.ca Published On :: Mon, 11 Nov 2024 14:46:23 EST Canada will be without captain Alphonso Davies for its upcoming CONCACAF Nations League quarterfinal against Suriname. Canada Soccer says the Bayern Munich star has withdrawn as a "precautionary measure due to physical fatigue." Full Article Sports/Soccer
qua Software unicorn Sirion appears to have moved its headquarters out of Washington By www.bizjournals.com Published On :: Wed, 13 Nov 2024 05:22:37 +0000 The contract software company closed a $110 million Series D round in 2023, one of the largest venture capital deals in Washington last year. Full Article
qua How to stay healthy during quarantine By www.starobserver.com.au Published On :: Wed, 01 Apr 2020 00:23:30 +0000 Eat well With isolation comes the three Bs: boredom, bingeing, and (can’t be) bothered. The evil accomplice of all three is comfort eating. While snacks and treats are okay now ... The post How to stay healthy during quarantine appeared first on Star Observer. Full Article Coronavirus (COVID-19) Healthy Living Life + Style covid19 health
qua Cuba hit by 6.8 magnitude earthquake after being battered by hurricanes and blackouts By www.cbc.ca Published On :: Sun, 10 Nov 2024 14:45:36 EST After weeks of hurricanes and blackouts have left many in Cuba reeling, an earthquake has left people shaken as rumbling was felt across the eastern stretch of the island, including in bigger cities like Santiago de Cuba, as well as Holguin and Guantanamo. Full Article News/World
qua What Was the Strongest Earthquake Ever Recorded? By science.howstuffworks.com Published On :: Thu, 24 Oct 2024 10:25:02 -0400 Earthquakes are among the most powerful natural forces on Earth, often causing widespread devastation, triggering tsunamis and altering the landscape of a region. But how strong was the strongest earthquake of all time? Full Article
qua cancer and aquarius compatibility By science.howstuffworks.com Published On :: Sat, 09 Nov 2024 05:00:04 -0500 Discover if Cancer and Aquarius can make a love match! Learn about their compatibility, strengths, challenges, and what to expect in a relationship. Full Article