ea Revise OBC creamy layer limit, say MPs at House panel meeting By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:27:44 +0530 They say that many OBC candidates have been unable to join the Civil Services despite clearing the exam Full Article India
ea Omar seeks compensation from Centre over losses due to Indus Water Treaty By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:34:51 +0530 Jammu and Kashmir Chief Minister’s remarks that the IWT hinders J&K’s power capacity spark row; the focus should be the return of power projects from National Hydroelectric Power Corporation, says former Chief Minister Mehbooba Mufti Full Article India
ea BJP accuses Congress of releasing election manifesto during “silence” period in Jharkhand By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:40:16 +0530 Mr. Patra claimed that the Congress wanted to give 4% reservation to the Muslim organisations and contractors in public tenders Full Article Jharkhand Assembly
ea BRSV and AISF demand thorough probe into RGUKT student’s death By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:02:18 +0530 Full Article Telangana
ea KTR in Delhi to strike a deal with BJP to escape Formula-E probe: Bhatti By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:47:03 +0530 Deputy Chief Minister points to BRS call to Maharashtra voters not to vote for Congress Full Article Telangana
ea Global fossil emissions to reach record high in 2024; India's share to rise by 4.6%: Report By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 10:10:34 +0530 According to a UN report released last month, India's greenhouse gas emissions surged by 6.1 per cent in 2023, contributing to 8 per cent of the global total Full Article News
ea US Deputy Secretary of State Kurt Campbell to attend inaugural US India Indian Ocean Dialogue in Delhi By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 10:42:54 +0530 During his visit, on November 13-14, Campbell will also participate in the Critical and Emerging Technologies (iCET) Intersessional to further expand cooperation between the United States and India on technological innovation and production Full Article News
ea Indian households accumulated USD 9.7 trillion in wealth over last ten years: Morgan Stanley By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:34:02 +0530 Full Article
ea 'Any relief on bank guarantee will be provided across the sector': Scindia on Vodafone Idea request for waiver of bank guarantees for spectrum By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:36:01 +0530 Full Article
ea India IT spending to reach USD 160 billion in 2025 fueled by application and infrastructure software market growth: Gartner By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:38:01 +0530 Full Article
ea Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06202G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu FangAbstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05657D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji HiranoA photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea 'PM Modi's govt gives highest priority to over 35 mn Indian diaspora', says EAM Jaishankar on website launch for Pravasi Bharatiya Divas By www.newkerala.com Published On :: Wed, 13 Nov 2024 16:04:01 +0530 Full Article
ea Providing better healthcare biggest priority: PM Modi ahead of Darbhanga AIIMS inauguration By www.newkerala.com Published On :: Wed, 13 Nov 2024 16:38:02 +0530 Full Article
ea Vistara's last flight from Odisha takes off for Delhi ahead of merger with Air India By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:06:02 +0530 Full Article
ea Fifth storm in a month bears down on the Philippines By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:49:22 +0530 The local government also reported knee-high floods across Santiago, a city of 1,50,000 people along an upper bank of the Cagayan river Full Article Environment
ea Xi leaves China for APEC meeting in Peru: state media By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:55:46 +0530 Chinese leader Xi Jinping travels to Peru for APEC summit amid trade tensions with U.S., inaugurates Chinese-funded port Full Article News
ea 5.3 magnitude earthquake jolts parts of Pakistan By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:40:21 +0530 No casualties have been reported so far for the earthquake that had its epicentre around the Hindukush mountain range Full Article World
ea In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3674-3694DOI: 10.1039/D4MD00580E, Research ArticleJinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin JinOridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3704-3710DOI: 10.1039/D4MD00552J, Research ArticleJaeyong Jung, Jeong Soo Sung, Soonil Kwon, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul PyunFv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3853-3861DOI: 10.1039/D4MD00165F, Research ArticleJiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang LiuThe synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3695-3703DOI: 10.1039/D4MD00546E, Research ArticleMiyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke DemizuA novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
ea T.N. govt. to take a call on verifying criminal antecedents before appointing schoolteachers By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:15:58 +0530 It also assures Madras High Court of putting in place an effective complaint redressal mechanism in the interest of school students Full Article Tamil Nadu
ea Leaders of various parties condemn attack on govt. doctor By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:08:06 +0530 Full Article Tamil Nadu
ea Four Swedish companies, including IKEA, looking to set up base in Tamil Nadu: Swedish Ambassador to India By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:56:01 +0530 There are 70 Swedish companies in Tamil Nadu, employing about 25,000 people. But we want to do more, says Jan Thesleff Full Article Tamil Nadu
ea Delhi airport sees seven flight diversions owing to bad weather By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:39:37 +0530 The IMD reported that very dense fog began forming at around 5.30 a.m., resulting in a thick haze over various parts of Delhi Full Article Delhi
ea Delhi’s air quality turns ‘severe’ for first time this season: CPCB By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:52:21 +0530 According to Central Pollution Control Board data, Delhi’s air quality reaches ‘severe’ levels with AQI of 418 Full Article Delhi
ea Argentine monthly inflation falls to three-year low By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:31:10 +0530 Full Article Business
ea Vodafone Idea narrows Q2 loss to ₹7,176 crore By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:56:55 +0530 Full Article Business
ea Greaves Cotton Q2 net loss narrows to ₹14 crore By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:59:39 +0530 Full Article Business
ea Free and fair inquiry sought into death of snakebite victim in Srikakulam district By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:10:47 +0530 Son of the victim alleges that local medical and health officials misleading higher-ups regarding the incident Full Article Andhra Pradesh
ea Target is to to make 30,000 MT of sand available every day in East Godavari district, says Collector By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:25:35 +0530 P. Prasanthi warns boatmen associations of stringent action if they attempt to prevent vehicles transporting sand from the sand reaches Full Article Andhra Pradesh
ea Andhra Pradesh govt. reaffirms commitment to ‘irrigating every acre of farmland’ in State through river-interlinking projects By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:43:13 +0530 Full Article Andhra Pradesh
ea India’s office leasing soars 41% in 2024 amid rent hikes, supply crunch, and GCC growth: Cushman & Wakefield By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:20:06 +0530 In an interview to businessline, Cushman & Wakefield’s Veera talks about commercial space leasing outlook, trends, and rental and supply trends for the coming months Full Article Real Estate
ea GlobalLogic opens delivery centre in Hyderabad to spread wings, ramp up hiring in Telangana By www.thehindu.com Published On :: Wed, 13 Nov 2024 10:21:21 +0530 The company will consider spreading wings to one more such location, in addition to Mahbubnagar where it has about 350 employees Full Article Hyderabad
ea Hyderabad to get regional centre of Indian Institute of Creative Technology By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:34:11 +0530 All activities are going to start quickly. The facility in Hyderabad will be set up in the IMAGE Tower, said Secretary, Union Ministry of Information and Broadcasting Full Article Hyderabad
ea 29th Climate Conference (COP) tracker | Day 2 LIVE: Key speeches, UK NDC, and India’s reaction at 5 p.m. on November 13 By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:01:23 +0530 Vibhuti Garg, an Associate and Senior Energy Specialist with over 13 years of experience in the energy sector, will guide us through the implications of these financial negotiations and the potential impacts on global energy transitions and climate commitments at 5 p.m. on November 13 Full Article Environment
ea Uncontrolled diabetes increases risk of hearing loss; doctors call for more awareness, screening By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:04:48 +0530 Hearing loss occurs twice as frequently in patients with uncontrolled diabetes as compared to the non-diabetic population, doctors say, calling for screening to be included in routine diabetes care Full Article Health
ea Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36352-36369DOI: 10.1039/D4RA07074G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. CoveyPhotoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ea Karnataka Chief Minister Siddaramaiah says no proposal to ease night traffic ban through Bandipur By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:45:12 +0530 Deputy Chief Minister D.K. Shivakumar had stated, in Wayanad in Kerala, that the government would take all possible measures to lift night traffic ban through Bandipur, which had riled wildlife conservationists in Karnataka Full Article Karnataka
ea Satish Jarkiholi supporter to lead Belagavi DCC bank By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:13:34 +0530 Before the election, the three Jarkiholi brothers — Satish (Congress MLA), Ramesh (BJP MLA), and Balachandra (BJP MLA) — met in a private hotel in Belagavi to discuss the names of candidates Full Article Karnataka
ea KEA opposes fee reduction for recruitment examinations in Karnataka By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:47:00 +0530 Points out that the government does not provide any grant for conducting recruitment examinations Full Article Karnataka
ea No dearth of funds for development works: CM By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:39:24 +0530 Full Article Karnataka
ea Byelections: Polling passes off peacefully in Sandur By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:51:08 +0530 Full Article Karnataka
ea Kannada has survived because of native speakers from North Karnataka: Horatti By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:05:42 +0530 Full Article Karnataka
ea I've found ways and means to break it down: Ashwin on Smith's batting By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:21:04 +0530 The two seasoned campaigners would face off during the Border-Gavaskar Trophy starting November 22 in Perth Full Article Cricket