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Correction: Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders. [Additions and Corrections]

VOLUME 294 (2019) PAGES 2555–2568Due to publisher error, “150 l/mm” was changed to “150 liters/mm” in the second paragraph of the “Vibrational spectroscopy of samples” section under “Experimental Procedures.” The correct phrase should be “150 l/mm.”




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Russia's Imperial Nostalgia: Implications for the West

Invitation Only Research Event

31 January 2020 - 11:00am to 12:30pm

Chatham House | 10 St James's Square | London | SW1Y 4LE

Event participants

Sergei Medvedev, Professor, Faculty of Social Sciences, Higher School of Economics (Moscow)

Vladimir Putin’s goal of restoring Russia’s status as a great power has led to an aggressive foreign policy and confrontation with its immediate neighbours as well as Western countries.

Sergei Medvedev, author of The Return of the Russian Leviathan, will discuss the forces shaping Russian politics and society today as well as how a nostalgia for empire – still widespread in contemporary Russia - has shaped Moscow’s foreign policy.

Attendance at this event is by invitation only.

Event attributes

Chatham House Rule

Anna Morgan

Administrator, Ukraine Forum
+44 (0)20 7389 3274




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LGBT India Tours| Gay Lesbian Tour | Gay Travel Packages

LGBT India Tours offers best and full assurance services to the gay, lesbian and LGBT clients at affordable rates for reveling holidays and tourism packages to various destinations in India.




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Chemical leak at LG plant in India kills 11, about 1,000 injured

HYDERABAD, India (AP) — A gas leak at a chemical factory owned by a South Korean company in southern India early Thursday left at least 11 people dead and about 1,000 struggling to breathe. The chemical styrene, used to make plastic and...




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Safeguarding LGBT+ young people

Recent years have seen political and social progress for people who identify as LGBT+ (lesbian, gay, bisexual, and transgender; the “+” indicating inclusion of other minority sexual and gender identities). Yet international evidence shows ongoing health and social inequalities in this group, many of which emerge during adolescence and represent...




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Teleconsulting with Trish Greenhalgh and Fiona Stevenson

A new podcast from The BMJ, to help GP's feel more connected, heard, and supported. Subscribe on; Apple podcasts - https://bit.ly/applepodsDBI Spotify - https://bit.ly/spotifyDBI Google podcasts - https://bit.ly/googlepodsDBI In our first episode, we discuss the highs and lows of video consultations, and how coronavirus has altered the landscape...




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Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and I{kappa}B-{alpha}

Samar I. Itani
Jul 1, 2002; 51:2005-2011
Rapid Publications




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The Dysfunction of Functions in Abstract Algebra

Kathleen Melhuish & Kristen Lew Texas State University “[Functions] are completely different, which is what makes this course so challenging.” – Abstract Algebra Student Functions are hard for students, even students in abstract algebra courses. Even if students have seen … Continue reading




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Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations

Francesco Rubino
Jun 1, 2016; 39:861-877
Metabolic Surgery and the Changing Landscape for Diabetes Care




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Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations

Francesco Rubino
Jun 1, 2016; 39:861-877
Metabolic Surgery and the Changing Landscape for Diabetes Care




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A New Migration Policy for A New Era: A Conversation with Mexico's Interior Secretary Olga Sánchez Cordero

On her first official trip to Washington, DC, Secretary of the Interior Olga Sánchez Cordero offered a public address on Mexico’s new approach to migration policy at MPI. Her remarks and the event discussion were mostly conducted in Spanish, and this recording is of the simultaneous English interpretation. 




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Una nueva política migratoria para una nueva era: Una conversación con la Secretaria de Gobernación Olga Sánchez Cordero

Durante su primera visita oficial a Washington, DC, la Secretaria de Gobierno Olga Sánchez Cordero presento un discurso público sobre la nueva política migratoria de México en el Instituto de Políticas Migratorias.




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Amalgam separator deadline remains intact

The deadline for dental offices to install amalgam separators remains intact but the Environmental Protection Agency announced March 26 that it will be initiating “a new temporary enforcement discretion policy” during the COVID-19 pandemic.




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Global warming fuels algal bloom disrupting fisheries in Arabian Sea

A new scientific study published Monday found that global warming is fueling a destructive algal bloom that is disrupting fisheries in the Arabian sea.




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Performance of the ESC 0/1-h and 0/3-h Algorithm for the Rapid Identification of Myocardial Infarction Without ST-Elevation in Patients With Diabetes

OBJECTIVE

Patients with diabetes mellitus (DM) have elevated levels of high-sensitivity cardiac troponin (hs-cTn). We investigated the diagnostic performance of the European Society of Cardiology (ESC) algorithms to rule out or rule in acute myocardial infarction (AMI) without ST-elevation in patients with DM.

RESEARCH DESIGN AND METHODS

We prospectively enrolled 3,681 patients with suspected AMI and stratified those by the presence of DM. The ESC 0/1-h and 0/3-h algorithms were used to calculate negative and positive predictive values (NPV, PPV). In addition, alternative cutoffs were calculated and externally validated in 2,895 patients.

RESULTS

In total, 563 patients (15.3%) had DM, and 137 (24.3%) of these had AMI. When the ESC 0/1-h algorithm was used, the NPV was comparable in patients with and without DM (absolute difference [AD] –1.50 [95% CI –5.95, 2.96]). In contrast, the ESC 0/3-h algorithm resulted in a significantly lower NPV in patients with DM (AD –2.27 [95% CI –4.47, –0.07]). The diagnostic performance for rule-in of AMI (PPV) was comparable in both groups: 0/1-h (AD 6.59 [95% CI –19.53, 6.35]) and 0/3-h (AD 1.03 [95% CI –7.63, 9.7]). Alternative cutoffs increased the PPV in both algorithms significantly, while improvements in NPV were only subtle.

CONCLUSIONS

Application of the ESC 0/1-h algorithm revealed comparable safety to rule out AMI comparing patients with and without DM, while this was not observed with the ESC 0/3-h algorithm. Although alternative cutoffs might be helpful, patients with DM remain a high-risk population in whom identification of AMI is challenging and who require careful clinical evaluation.




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Algorhythms for Marketing Transformation

We all understand that digital media, data, and analytics are driving transformations in society and business. Most marketers are now armed with case studies of what can be done differently, but many are still challenged with how to truly develop new ideas and execute new strategies to grow their business. Mitch Joel, President of Mirum […]




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'Open Algorithms' Bill Would Jolt New York City Schools, Public Agencies

The proposed legislation would require the 1.1-million student district to publish the source code behind algorithms used to assign students to high schools, evaluate teachers, and more.




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Rage inside the machine : the prejudice of algorithms, and how to stop the internet making bigots of us all / Robert Elliott Smith.

Internet -- Social aspects.




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Late bloomers : the power of patience in a world obsessed with early achievement / Rich Karlgaard.

Self-actualization (Psychology) in old age.




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Diagnostik und allgemeine Symptomatologie der Lungenkrankheiten ... / von Albert Fraenkel.

Wien : Urban & Schwarzenberg, 1890.




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Die allgemeine chirurgische Pathologie und Therapie : in einundfünfzig Vorlesungen : ein Handbuch für Studirende und Aerzte / von Theodor Billroth und Alex. v. Winiwarter.

Berlin : G. Reimer, 1893.




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Die allgemeine chirurgische Pathologie und Therapie : in fünfzig Vorlesungen : ein Handbuch für Studirende und Aerzte / von Theodor Billroth.

Berlin : G. Reimer, 1863.




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Die allgemeine chirurgische Pathologie und Therapie : in fünfzig Vorlesungen : ein Handbuch für Studirende und Aerzte / von Theodor Billroth.

Berlin : G. Reimer, 1876.




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Die allgemeine Pathologie : Ein Hand- und Lehrbuch für Ärzte und Studierende 1. Bd: 1. Abt / von Otto Lubarsch.

Wiesbaden : Bergmann, 1905.




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Die Behandlung der hysterie der Neurasthenie und ähnlicher allgemeiner functioneller Neurosen / von V. Holst.

Stuttgart : F. Enke, 1883.




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Die diffuse Nephritis und die Entzündung im Allgemeinen / von E. Aufrecht.

Berlin : G. Reimer, 1879.




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Die Krankheiten der Nase und des Halses, ihre Beziehungen zum Gesammtorganismus und ihre Bedeutung für die Singstimme. Zehn allgemein verständliche Vorträge / von Dr Friedrich Ernst.

Berlin : Köllner, 1899.




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Die Krankheiten des Gehirns und seiner Adnexa im Gefolge von Naseneiterungen / von R. Dreyfuss.

Jena : G. Fischer, 1896.




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Die Mikroorganismen der Mundhöle : die örtlichen und allgemeinen Erkrankungen, welche durch dieselben hervorgerufen werden / von W.D. Miller.

Leipzig : G. Thieme, 1892.




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Die Nierenresection und ihre Folgen / von Max Wolff.

Berlin : A. Hirschwald, 1900.




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Die Pathologie der weiblichen Sexual-Organe : in Lichtdruck-Abbildungen, nach der Natur in Originalgrösse, durch anatomische und klinische Erfahrungen erläutert / von F. Winckel.

Leipzig : S. Hirzel, 1881.




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Die Prüfung des Farbensinnes beim Eisenbahn- und Marinepersonal. Neue Folge. 1. Lieferung. Tafeln zur Bestimmung der Roth-Grünblindheit / von Dr. J. Stilling.

Cassel : T. Fischer, 1878.




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Die Taubheit infolge von Meningitis cerebrospinalis epidemica / von Ferdinand Alt.

Leipzig : F. Deuticke, 1908.




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Die Ursache des Krebses und der Geschwülste im allgemeinen / von H. Spude.

Berlin : Gose & Tetzlaff, 1904.




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Die Verunreinigung der Gewässer, deren schädliche Folgen, sowie die Reinigung von Trink-und Schmutzwasser / von J. Konig.

Berlin : J. Springer, 1899.




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Die Wechselbeziehungen in der menschlichen Pathologie und Therapie : eine allgemein-medizinische Studie / von S. Laache.

Stuttgart : Enke, 1905.




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Diseases of the nervous system : being a treatise on spasmodic, paralytic, neuralgic and mental affections : for the use of students and practitioners of medicine / by Charles Porter Hart.

London : Boericke & Tafel, 1881.




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Dr. Joh. Christ. Aug. Heyse's Allgemeines verdeutschendes und erklärendes Fremdwörterbuch mit Bezeichnung der Aussprache und Betonung der Wörter nebst genauer Angabe ihrer Abstammung und Bildung / neu bearb., vielf. berichtigt u. verm v

Hannover : Hahn, 1873.




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Du traitement des maladies du coeur par la méthode des Drs Schott, de Nauheim / par le docteur Moeller, médecin praticien à Bruxelles, membre titulaire de l'Académie royale de médecine de Belgique, etc / par la methode des drs

Bruxelles : A. Manceaux, 1893.




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Einfuhrung in die praktische Nahrungsmittelchemie / bearbeitet von Hermann Thoms; Botanisch-Mikroskopischer Teil bearbeitet von Ernst Gilg.

Leipzig : S. Hirzel, 1899.




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Epilepsy : its pathology and treatment : being an essay to which was awarded a prize of four thousand francs by the Academie Royale de Médécine de Belgique, December 31, 1889 / by Hobart Amory Hare.

London : Philadelphia, 1890.




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Erkenntniß und Behandlung der Frauenkrankheiten im allgemeinen : 4 Vorträge, in d. Gynäkolog. Klinik zu Kiel im Sommer-Semester 1885 / gehalten von Carl Conrad Theodor Litzmann.

Berlin : Hirschwald, 1886.




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LGBTQ Issues Roil Florida School-Choice Debate

As lawmakers weigh expansion of the state’s voucher and tax-credit scholarship programs, some renew a push for anti-discrimination protection for lesbian, gay, bisexual, transgender, and queer students.




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Capitals dump Leipsic after vulgar comments

The Washington Capitals decided to part ways with forward Brendan Leipsic on Friday after he made vulgar and disparaging comments on an social media chat group. The 25-year old Canadian was placed on waivers by the NHL club after his Instagram group chat messages were leaked earlier this week. The chat included inappropriate remarks about Edmonton Oilers forward Connor McDavid's girlfriend and the wife of Vancouver Canucks player Tanner Pearson.




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LGBTK : ne demek?




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Contemporary research in pain and analgesia, 1983 / editors, Roger M. Brown, Theodore M. Pinkert, Jacqueline P. Ludford.

Rockville, Maryland : National Institute on Drug Abuse, 1983.




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Gulgong now!

Martin Polkinghorne of Collection Preservation and Storage recently travelled to Hill End, Mudgee and Gulgong for a shor




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Statistical convergence of the EM algorithm on Gaussian mixture models

Ruofei Zhao, Yuanzhi Li, Yuekai Sun.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 632--660.

Abstract:
We study the convergence behavior of the Expectation Maximization (EM) algorithm on Gaussian mixture models with an arbitrary number of mixture components and mixing weights. We show that as long as the means of the components are separated by at least $Omega (sqrt{min {M,d}})$, where $M$ is the number of components and $d$ is the dimension, the EM algorithm converges locally to the global optimum of the log-likelihood. Further, we show that the convergence rate is linear and characterize the size of the basin of attraction to the global optimum.




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Sparse equisigned PCA: Algorithms and performance bounds in the noisy rank-1 setting

Arvind Prasadan, Raj Rao Nadakuditi, Debashis Paul.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 345--385.

Abstract:
Singular value decomposition (SVD) based principal component analysis (PCA) breaks down in the high-dimensional and limited sample size regime below a certain critical eigen-SNR that depends on the dimensionality of the system and the number of samples. Below this critical eigen-SNR, the estimates returned by the SVD are asymptotically uncorrelated with the latent principal components. We consider a setting where the left singular vector of the underlying rank one signal matrix is assumed to be sparse and the right singular vector is assumed to be equisigned, that is, having either only nonnegative or only nonpositive entries. We consider six different algorithms for estimating the sparse principal component based on different statistical criteria and prove that by exploiting sparsity, we recover consistent estimates in the low eigen-SNR regime where the SVD fails. Our analysis reveals conditions under which a coordinate selection scheme based on a sum-type decision statistic outperforms schemes that utilize the $ell _{1}$ and $ell _{2}$ norm-based statistics. We derive lower bounds on the size of detectable coordinates of the principal left singular vector and utilize these lower bounds to derive lower bounds on the worst-case risk. Finally, we verify our findings with numerical simulations and a illustrate the performance with a video data where the interest is in identifying objects.




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A fast MCMC algorithm for the uniform sampling of binary matrices with fixed margins

Guanyang Wang.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1690--1706.

Abstract:
Uniform sampling of binary matrix with fixed margins is an important and difficult problem in statistics, computer science, ecology and so on. The well-known swap algorithm would be inefficient when the size of the matrix becomes large or when the matrix is too sparse/dense. Here we propose the Rectangle Loop algorithm, a Markov chain Monte Carlo algorithm to sample binary matrices with fixed margins uniformly. Theoretically the Rectangle Loop algorithm is better than the swap algorithm in Peskun’s order. Empirically studies also demonstrates the Rectangle Loop algorithm is remarkablely more efficient than the swap algorithm.