New partnership is part of GSK’s R&D face-lift, which includes an increased focus on immune system targets

Companies are hoping to use the vesicles to package small-molecule, protein, and RNA drugs or even use them as therapies themselves

In India, many players are in the throes of chaos and pain but at least one partnership -- Air Asia India -- that was fraying even before the pandemic now finds itself at breaking point, says Anjuli Bhargava.

The new year will see a line of hatchbacks (including compact SUVs) hit the Indian roads.Rajesh Karkera/Rediff.com offers a peek.

R. Ramoo completes the the gruelling two-day biking challenge set by the Iron Butt Association

The Air Quality Index (AQI) of the national capital remained in 'very poor' category for the 15th consecutive day on Wednesday, i.e., November 13.

Demand for delivery services is skyrocketing across Asia as travel curbs keep more people at home.

The post Delivery services in SEA face game-changing moment amid virus scare appeared first on DealStreetAsia.

The anti-monopoly watchdog received complaints that food delivery platforms have increased their service fees for restaurants from 20% to up to 40%.

The post Thailand warns food delivery apps against overcharging amid COVID-19 outbreak appeared first on DealStreetAsia.

What is the difference between removal of goods and delivery of goods?

City state yet to benefit from rebound in global oil market

From tweet to tweet, official to official, nobody can tell what his priorities are

Much before the pandemic mayhem and lockdown happened, Vanita Rathod, 32, a godown manager at Petlad town of Anand district, was sanctioned maternity leave. But first ‘janta curfew’ took place and then lockdown and Rathod saw things going beyond her personal discomfort.

Priyanka Chopra has been spending the quarantine time with her husband, Nick Jonas and their two adorable dogs. And with a very special and curious make-up artist. The first Monday of May is the Met Gala day and the event,

According to recent reports by WHO, there are 2,303,312 COVID-19 infected persons around the world, with 270,765 deaths. Researchers and health experts around the globe are ardently focused on studying the novel coronavirus, where new findings and understanding help in the

Online Resource

Chief minister Yogi Adityanath has set an 11-point agenda for drawing up a roadmap for economic revival of the state.The details of the agenda were finalised after a high-powered meeting chaired by the CM on May 4.

1. Coronavirus crisis: Premier Mark McGowan details phase two of WA’s road to recovery to roll out May 18  The West Australian
2. WA to ease coronavirus restrictions from May 18, with 20-person gatherings allowed  ABC News
3. WA to return to work from May 18  NEWS.com.au
4. WATCH LIVE: Premier Mark McGowan reveals which restrictions will be eased in WA’s coronavirus recovery plan  The West Australian
5. No new coronavirus cases in WA for ninth time in 10 days, as research fund launched  ABC News
6. View Full coverage on Google News

““Travel is to discover everyone else is wrong about other countries””

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Aldous Huxley (via preferred-destinations)

Princeton University researchers have found that the roundworms Caenorhabditis elegans have a sure-fire method of ensuring a steady supply of a bacteria they eat — they grow their own. The worms carry the bacteria Escherichia coli along with them, and drop bacteria along the way to create thriving new bacterial colonies that the worms later return to "harvest" and eat.

(WASHINGTON) - Today, the U.S. Environmental Protection Agency (EPA) nationally recognizes the exceptional accomplishments of 15 businesses and organizations participating in EPA’s Food Recovery Challenge.

Edwin Cabrera, a father of two, was unlocking his e-bike after dropping off a pizza on Fort George Hill near Fairview Ave. on May 3 when two suspects jumped out of the shadows and attacked him around 9 p.m.

Exclusive: 'As well as staggered working hours we need to stagger holidays,' says AA president Edmund King

DR Rosemary answers your health concerns.

Visit CTVNews.ca for an interactive record of the COVID-19 outbreak in Canada.

A Saskatoon family physician wanted to find a way to help send supplies to the northern community of La Loche and set an initial goal for $15,000 - but within days the donations total over $26,000.

The Tech Stuff You Use Everyday is Dirtier Than You Think!

The Tech Stuff You Use Everyday is Dirtier Than You Think!

Filed under: Skiing, North America, United States

• 16 Easy Ski Vacation Ideas from U.S. Cities
• 50 Ways to Ski in 50 States

Where to Ski In Every State and 16 Ski Vacations Near Big U.S. Cities originally appeared on Gadling on Thu, 05 Dec 2013 11:29:00 EST. Please see our terms for use of feeds.

After six weeks of negotiating, the UN Security Council was close to agreeing on a resolution for a global ceasefire during the Covid-19 pandemic. Seems fair, right? Let's agree to stop killing each other for a while, so we can focus on the virus that's killing us instead?

China proposed that the text explicitly mention a commitment by member nations to support the efforts of the World Health Organization — who Donald Trump has blamed (without evidence) for withholding information on the coronavirus outbreak.

So the US looked at the resolution and said "LOL no," despite last minute efforts to reach a compromise. As The Guardian reports:

On Thursday night, French diplomats thought they had engineered a compromise in which the resolution would mention UN “specialized health agencies” (an indirect, if clear, reference to the WHO).

The Russian mission signaled that it wanted a clause calling for the lifting of sanctions that affected the delivery of medical supplies, a reference to US punitive measures imposed on Iran and Venezuela. However, most security council diplomats believed Moscow would withdraw the objection or abstain in a vote rather than risk isolation as the sole veto on the ceasefire resolution.

While everyone else seemed game to go along with these compromises, the US insisted it was one big Chinese trick. As one diplomat told CNN:  "This discussion has been taken hostage by issues that do not have to do with the real issues at stake. Instead it has been transformed into a fight between the US and China. Read the rest

President Trump said Friday he had watched the video of Ahmaud Arbery being shot and found it “very disturbing” and “heartbreaking,” but said he was confident that the Georgia legal system would come down on the side of justice.

The dextransucrase DSR-OK from the Gram-positive bacterium Oenococcus kitaharae DSM17330 produces a dextran of the highest molar mass reported to date (∼109 g/mol). In this study, we selected a recombinant form, DSR-OKΔ1, to identify molecular determinants involved in the sugar polymerization mechanism and that confer its ability to produce a very-high-molar-mass polymer. In domain V of DSR-OK, we identified seven putative sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are known to be involved in glucan binding. We investigated their role in polymer synthesis through several approaches, including monitoring of dextran synthesis, affinity assays, sugar binding pocket deletions, site-directed mutagenesis, and construction of chimeric enzymes. Substitution of only two stacking aromatic residues in two consecutive sugar-binding pockets (variant DSR-OKΔ1-Y1162A-F1228A) induced quasi-complete loss of very-high-molar-mass dextran synthesis, resulting in production of only 10–13 kg/mol polymers. Moreover, the double mutation completely switched the semiprocessive mode of DSR-OKΔ1 toward a distributive one, highlighting the strong influence of these pockets on enzyme processivity. Finally, the position of each pocket relative to the active site also appeared to be important for polymer elongation. We propose that sugar-binding pockets spatially closer to the catalytic domain play a major role in the control of processivity. A deep structural characterization, if possible with large-molar-mass sugar ligands, would allow confirming this hypothesis.

ADVISORY COLUMN: SMALL BUSINESS On Thursday, May 7, the RJR/GLEANER Communications group staged a virtual town hall meeting on Television Jamaica titled “COVID-19...

He catches the fish, breathes on them, then throws them back. These infected fish will infect all bodies of water with Covid-19. He goes saltwater and fresh water fishing 

Examples being: XTro (UK), Oldboy (S.Korea), Girl With a Dragon Tattoo (Sweden), Predestination (Australia) ... something like these

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled the field to flourish.

New Brunswick has entered the next COVID-19 recovery phase, triggering a new round of loosened restrictions and reopening a large swathe of the economy, Premier Blaine Higgs announced Friday.

Players and everyone else need to live with this virus: Gambhir  Hindustan TimesCricketers will have to live with dangers of COVID-19: Gautam Gambhir  Times of IndiaPlayers will need to live with this virus in foreseeable future: Ga...

When an MDT participant’s family member commits suicide, she becomes puzzled and angry. But with encouragement from others, she recognises God’s compassion.

OM Philippines-Cebu conducts critical incident stress debriefing training with partner organisations and churches in Cebu City, Northern Cebu and Bohol Island.

Slobodan never thought he could be free, but Jesus gave him a new start. Now Slobodan urges Roma in Croatia and Serbia that there is a better way.

Ofentse Mokwena discusses what's needed for opening transport markets and unbundling transport SOEs.

The leader said: "This is a secret; if we started to teach about Jesus in our mosques then we might as well open churches."