Lab Chip, 2020, 20,1358-1389
DOI: 10.1039/C9LC01112A, Critical Review

Fumihiro Sassa, Gokul Chandra Biswas, Hiroaki Suzuki
Electrochemistry provides possibilities to realize smart microdevices of the next generation with high functionalities.
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Lab Chip, 2020, 20,1390-1397
DOI: 10.1039/D0LC00021C, Communication

Bo Wang, Ximiao Wen, Yan Cao, Shan Huang, Hoa A. Lam, Tingyi “Leo” Liu, Pei-Shan Chung, Harold G. Monbouquette, Pei-Yu Chiou, Nigel T. Maidment
PDMS thin-film transfer and enzyme microstamping enabled 3-in-1 Si/PDMS hybrid chemtrode for multi-analyte sensing and chemical delivery in vivo.
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Lab Chip, 2020, 20,1461-1471
DOI: 10.1039/C9LC01097A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mario Rothbauer, Gregor Höll, Christoph Eilenberger, Sebastian R. A. Kratz, Bilal Farooq, Patrick Schuller, Isabel Olmos Calvo, Ruth A. Byrne, Brigitte Meyer, Birgit Niederreiter, Seta Küpcü, Florian Sevelda, Johannes Holinka, Oliver Hayden, Sandro F. Tedde, Hans P. Kiener, Peter Ertl
We demonstrate that the integration of complex human synovial organ cultures in a lab-on-a-chip provides reproducible and reliable information on how systemic stress factors affect synovial tissue architectures using light scatter biosensing.
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Lab Chip, 2020, 20,1493-1502
DOI: 10.1039/C9LC01039D, Paper

Zachary Ballard, Sarah Bazargan, Diane Jung, Shyama Sathianathan, Ashley Clemens, Daniel Shir, Saba Al-Hashimi, Aydogan Ozcan
A rapid and cost-effective method for monitoring proteins in tear-fluid is reported, which enables biomarker monitoring using contact lenses toward personalized mobile-health applications.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01226E, Paper

Jia Liu, Guoyun Sun, Shih-Chung Wei, Song Guo, Weikang Nicholas Lin, Chia-Hung Chen
Nanoplasmon-enhanced drop screen is developed to measure single-cell multiple miRNAs with high sensitivity of 0.1 nM, addressing cell nucleocytoplasmic profile in a throughput ∼100 cells per minute.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01028A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yan Jiang, Theodore Feldman, Julia A. M. Bakx, Darren Yang, Wesley P. Wong
High-speed hydrodynamic trapping enables combined surface-free force spectroscopy and fluorescence imaging of single DNA molecules at extreme forces.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01192G, Paper

Roman Mikhaylov, Fangda Wu, Hanlin Wang, Aled Clayton, Chao Sun, Zhihua Xie, Dongfang Liang, Yinhua Dong, Fan Yuan, Despina Moschou, Zhenlin Wu, Ming Hong Shen, Jian Yang, Yongqing Fu, Zhiyong Yang, Christian Burton, Rachel J. Errington, Marie Wiltshire, Xin Yang
We demonstrate a novel SAW device fabrication technique by mechanically clamping interdigital electrodes (IDEs) on the printed circuit board (PCB) to a LiNbO₃ wafer. The novel PCB-SAW device is capable of performing all the functions of standard SAW devices.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00263A, Paper

Jaime L. Korner, Elanna B. Stephenson, Katherine S. Elvira
A new type of pharmacokinetic compartment model using artificial cell membranes that predicts intestinal absorption three times more accurately than the current state of the art.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper

W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper

Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00213E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ioannis Lignos, Hendrik Utzat, Moungi G. Bawendi, Klavs F. Jensen
We present a flow-based system coupled with an optical interferometry setup for the extraction of single nanocrystal properties.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00175A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Karl Olofsson, Björn Hammarström, Martin Wiklund
A novel, simple and robust route for binary separation of viable and dead cells using a density modified medium which takes advantage of the compromised cell membrane of dead cells.
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Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00133C, Paper

George Banis, Luke Beardslee, Justin Stine, Rajendra Mayavan Sathyam, Reza Ghodssi
Ingestible capsule systems continue evolving to overcome drawbacks associated with traditional gastrointestinal (GI) diagnostic and therapeutic processes, such as location restrictions or insufficient sensitivity measures when obtaining information on local...
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Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper

Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
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Lab Chip, 2020, 20,1577-1585
DOI: 10.1039/D0LC00024H, Paper

Jingjing Guo, Li Lin, Kaifeng Zhao, Yanling Song, Mengjiao Huang, Zhi Zhu, Leiji Zhou, Chaoyong Yang
An automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method that reduces the bead loss.
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Lab Chip, 2020, 20,1687-1693
DOI: 10.1039/C9LC01021A, Paper

Zongdai Liu, Dan Luo, Kun-Lin Yang
The concentration of toluene vapor is obtained based on polymer-stabilized liquid crystals by viewing a colourful gamut under a polarized optical microscope.
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Lab Chip, 2020, 20,1612-1620
DOI: 10.1039/D0LC00089B, Paper

Baris R. Mutlu, Taronish Dubash, Claudius Dietsche, Avanish Mishra, Arzu Ozbey, Kevin Keim, Jon F. Edd, Daniel A. Haber, Shyamala Maheswaran, Mehmet Toner
Cell–cell adhesion strength of freely suspended cell clusters can be measured using an oscillatory inertial microfluidic system.
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Lab Chip, 2020, 20,1676-1686
DOI: 10.1039/D0LC00244E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Andreas Kleiber, Anuradha Ramoji, Günter Mayer, Ute Neugebauer, Jürgen Popp, Thomas Henkel
The control of the focus plane allows multi-directional imaging flow cytometry.
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Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00354A, Paper

Naotomo Tottori, Takasi Nisisako
We propose sheath-free microfluidic deterministic lateral displacement devices with inertially focused single straight input.
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DOI: 10.1021/acs.jcim.9b01103

DOI: 10.1021/acs.jcim.9b01107

DOI: 10.1021/acs.jcim.9b01099

DOI: 10.1021/acs.jcim.9b01121

DOI: 10.1021/acs.jcim.9b01178

DOI: 10.1021/acs.jcim.9b01111

DOI: 10.1021/acs.jcim.9b01015

DOI: 10.1021/acs.jcim.9b01167

DOI: 10.1021/acs.jcim.9b01102

DOI: 10.1021/acs.jcim.0c00334

DOI: 10.1021/acs.jcim.9b01075

DOI: 10.1021/acs.jcim.0c00065

DOI: 10.1021/acs.jcim.0c00179

DOI: 10.1021/acs.jcim.9b01194

DOI: 10.1021/acs.jcim.9b01161

DOI: 10.1021/acs.jcim.9b00968