Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein.

A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened.

A surgical stapling device particularly suited for endoscopic procedures is described. The device includes a handle assembly and an elongated body extending distally from the handle assembly. The distal end of the elongated body is adapted to engage a disposable loading unit. A control rod having a proximal end operatively connected to the handle assembly includes a distal end extending through the elongated body. A control rod locking member is provided to prevent movement of the control rod until the disposable loading unit is fully secured to the elongated body of the stapling device.

A surgical stapling instrument can comprise, one, a handle comprising an actuator and, two, an end effector comprising a proximal end, a distal end, and a longitudinal axis extending between the proximal end and the distal end. The end effector can further comprise a first jaw configured to support staples comprising staple legs and, in addition, a second jaw supporting a matrix element opposite the staples, wherein one of the jaws is movable toward the other in order to engage the matrix element with the staple legs. The stapling instrument can further comprise a cam operably coupled with the actuator, wherein the cam is movable along the longitudinal axis to deform the staple legs.

Disclosed herein is a colorless or pale-colored liquid composition comprising a cationic substance, wherein the liquid composition contains in combination a cationic substance and a nonionic polymeric substance.

Disclosed is a method for producing Alkyllithium compounds by reacting metallic lithium with an Alkyl halide in a solvent. The reaction is performed at a reduced pressure at the boiling point of the solvent.

A mask for forming polysilicon has a first slit region where a plurality of horizontal slit patterns are arranged in the vertical direction while bearing the same width, a second slit region where a plurality of horizontal slit patterns are arranged in the vertical direction while bearing the same width, a third slit region where a plurality of horizontal slit patterns are arranged in the vertical direction while bearing the same width, and a fourth slit region where a plurality of horizontal slit patterns are arranged in the vertical direction while bearing the same width. The slit patterns arranged at the first to fourth slit regions are sequentially enlarged in width in the horizontal direction in multiple proportion to the width d of the slit pattern at the first slit region. The centers of the slit patterns arranged at the first to fourth slit regions in the horizontal direction are placed at the same line. The slit patterns arranged at the respective slit regions in the vertical direction are spaced from each other with a distance of 8*d. Alternatively, the first to fourth slit regions may be arranged in reverse order, or in the vertical direction.

An improved method of producing a friction material for use in the production of brake pads. A first mixing step blends binder, fiber, and filler materials together in a mixer to create a pre-mix, with one of the materials doubling as a wetting agent promoting the homogeneity of the mixture. A second non-asbestos material is added to the pre-mix in the same mixer, and the two are mixed together to produce the final friction material.

A method for creating multiple punch holes during a finishing process of paper sheets and other sheet materials. A highlight of the present invention is the ability to select between at least two configurations of punch holes automatically, without manual adjustment, and “on-the-fly” without interruption of the sheet or paper flow. The perforation method utilizes two rotatable punches set at different angles such that when one intersects the sheet path, the other clears the sheet path. The speed of rotation is controlled such that the non-selected punch intersects the sheet path in a space between pitches.

A punching machine comprising at least one punching head including a support body having a first end delimiting a peripheral shoulder, a second end, and at least two parallel seats being angularly spaced from one another and extending through said support body from said first end to said second end; a punching tool holder slibably mounted in at least one of said seats; a multiplicity of removable resilient means angularly spaced from one another, each having a first end resting on said peripheral shoulder and a second end facing away from said peripheral shoulder; an annular cap member arranged in front and spaced from said peripheral shoulder and designed to abut against said second end of said resilient means; a rotor member mounted for rotation on said annular cap member and having an inner face thereof facing towards said punching tool holder; a sliding member projecting from said inner face and arranged to slide onto said punching tool holder when said rotor member rotates; and driving means designed to stepwise drive said rotor member, whereby locating said sliding member onto a pre-selected punching tool holder.

The present invention discloses a log sawing system comprising multiple cutting blades. The multiple cutting blades are positioned to cut laterally or perpendicular to the centerline of the log which is to be cut. The logs are transported into cutting position using some type of log positioner. The multiple cutting blades are rotatably mounted on an arm which is pivotally mounted on a shaft in groups, being driven by an electrical or like motor, all of which are mounted onto a platform positioned adjacent to the log to be cut. Hydraulic lifters are used to partially rotate the saw blades into the cutting position adjacent the log. Means utilizing a computer and lasers are provided to develop a log cutting solution to best utilize the logs.

A pressing structure for a hole-punching unit includes an axle, two wrenching pieces, a pole and two pressing pieces, wherein the axle is axially attached to a case of the hole-punching unit, with one end of the axle axially connecting to a control knob, each wrenching piece connecting to the axle near its end, the pressing piece having a spring coil disposed at its middle and pivotally connected to the pole, and the pressing piece having a pair of lapping portions extending from a first side of the spring coil, and a pair of suppressing portions extending from a second side of the spring coil, the lapping portions leaning against an upper edge of the wrenching piece for the control knob to drive the wrenching piece to move synchronously, so as to let the suppressing portions to press the hole-punching assembly and to fasten the hole-punching assembly.

A method for producing cottage cheese by using Streptococcus thermophilus bacteria.

The present invention provides a food preservation system that includes an absorbent food pad that has absorbent material to absorb exuded liquids from a food product, and has an oxygen scavenging system to modify the atmosphere in the food package. Also described is a method of using the absorbent food pad to enhance appearance of the food product and extend shelf life.

The present invention is directed to a soybean plant with mutations in FAD2-1A and FAD2-1B. Moreover, the present invention is directed to seeds from said plants with altered ratios of monosaturated and polyunsaturated fats. In particular, the present invention is directed to plants where the plants exhibit elevated levels of oleic acid.

Disclosed is a method of increasing lean body mass and reducing fat body mass in infants, said method comprising administration to an infant, term or preterm, a nutritional formula comprising a source of DHA and ARA. It has been found that the administration of DHA and ARA, or a source thereof, in infants can increase lean body mass and reduce fat body mass, when compared to an unsupplemented control formula, without impacting the total overall growth of the infant. This method is especially useful in preterm infants.

An exemplary center housing rotating assembly includes a turbine wheel (260); a compressor wheel (240); a center housing (210) that includes a through bore (215), extending from a compressor end to a turbine end along a bore axis, and a recess (217), adjacent the bore, in a plane orthogonal to the bore axis; a bearing assembly (230) positioned in the bore that includes a keyway (233); and an anti-rotation component (280) seated in the recess and at least partially in the keyway to restrict rotation of the bearing assembly in the bore. Various other exemplary devices, systems, methods, etc., are also disclosed.

An electronic system for enhancing camera focusing on a portable electronic device is disclosed. The system comprises a body, a bus, and a camera module coupled to the bus and comprising a photosensitive substrate and a lens assembly wherein the lens assembly comprises a lens capable of being selectively moved to a distance from the photosensitive substrate for light focus thereon. Further, it comprises an accelerometer coupled to the bus and configured to generate orientation information, said orientation information indicating contemporaneous orientation of the body with respect to a predetermined reference. It also comprises a memory and a processor coupled to the bus. The memory comprises instructions that when executed implement an autofocus program configured to automatically determine the distance based on: 1) image data captured by said camera module; and 2) the orientation information generated by the accelerometer.

An image sensing and printing digital camera device includes a housing defining a slot for receiving a printed instruction card having printed thereon an array of dots representing a programming script, the housing further storing therein a roll of print media; an area image sensor for sensing an image and generating pixel data representing the image; a linear image sensor for scanning the array of dots on the card and converting the array of dots into a data signal; a microcontroller provided in the housing, the microcontroller for decoding the data signal into the programming script and applying the programming script on the pixel data; and a printing mechanism for printing the pixel data, having applied thereto the programming script, on the roll of print media. The microcontroller integrates on a single chip a VLIW processor, a printhead interface, and an output buffer effecting communication between the VLIW processor and the printhead interface.

The linear position of an object is estimated using multiple magnetic field sensors and a magnet. The multiple magnetic field sensors are held in fixed relation to one another and in moving relation with respect to the magnet. Readings of the first and second magnetic field sensors and the fixed distance between the first and second magnetic field sensors may be used to estimate the linear position. In some embodiments, an estimated frequency of an approximately sinusoidal field versus position characteristic is also used as part of the estimation.

A toy apparatus and method for interactive communication between a cellphone and a toy apparatus is disclosed. In an embodiment of the present invention, a method is provided, the method including: transmitting by the cellphone at least one signal; receiving by the toy apparatus the at least one signal; analyzing by the toy apparatus the at least one signal; determining by the toy apparatus at least one response to the at least one signal; and producing by the toy apparatus the at least one response.

A method, system, and apparatus are provided for interactively playing with a printed image. A printed image resembling a game board, book, or picture, is provided. The printed image includes a registration area and a plurality of feedback areas in which an indicator color is printed at a predetermined level, e.g. percentage of area. A figurine is provided that includes a light source and light sensor. The light source and light sensor are placed in proximity to the designated areas in the image to sense the level of the indicator color printed therein and an associated output is provided. The registration area is useable to identify a predefined template associated with the image to allow feedback of the figurine with a plurality of different printed images. The figurine can include an ultraviolet light source to activate graphics printed in the image with photochromic ink.

A multi-color harmonic synthesized laser system for laser processing and a laser processing method using multi-color harmonic synthesized laser are disclosed. The multi-color harmonic synthesized laser system includes a laser source for providing a single laser wave, a converter for converting the single laser wave into a plurality of harmonic waves with different frequencies, and a modulating unit for modulating amplitudes and relative phases of the harmonic waves to form a plurality of modulated harmonic waves, so as to synthesize the modulated harmonic waves as a single synthesized laser wave, wherein the single synthesized laser wave is focused on an object to perform a laser processing. The converter includes a plurality of non-linear crystals for converting the single laser wave into a fundamental harmonic wave and a plurality of multi-frequency harmonic waves. The harmonic waves are coherent and collinear, and the phases of the harmonic waves are related to one another.

A high power fiber laser system emitting a substantially diffraction limited beam with a Gaussian intensity profile includes a single mode (“SM”) neodymium fiber pump source outputting a SM pump light; a seed laser operative to emit a SM signal light at a wavelength greater than that of the pump light; a SM DWM receiving and multiplexing the SM pump and signal lights. The disclosed system further includes a booster fiber amplifier which is configured with a frustoconically-shaped ytterbium (“Yb”) doped core receiving the pump and signal lights and configured with a small diameter input end which supports only a SM and a large diameter output end which is capable of supporting the SM and high order modes (:HOM”). The booster further has a cladding surrounding and coextending with the core, the core being configured for having intensity profiles of respective SMs of pump and signal lights overlap one another so that an overlap integral substantially equals to one (1) along an entire length of the core. The SM of the light signal extracts substantially the entire energy from the pump mode leaving the HOMs without amplification necessary to affect a quality of the diffraction limited beam of the system in a MW peak power range and hundreds of watt average power range.

Singlet oxygen metastables can be formed. A catalytic coating is formed on an interior surface of a flow reactor, and an oxygen containing species is flowed into the flow reactor to produce singlet oxygen metastables by a chemical reaction in the presence of the catalytic coating.

Proposed is an image processing apparatus in which the data processing method is changed over in suitable fashion in accordance with job settings when binding is performed. To accomplish this, the image processing apparatus is such that when stored image data is processed, the output format is determined from a job ticket and processing for dividing image data is controlled in accordance with the output format determined. In accordance with the output format determined, the apparatus changes over the output timing of divided page image data.

A device is provided to shape a spine of a book casing positioned horizontally spread out flat and oriented to be distributed evenly over a spine of a book block. Two fold-shaping rails are arranged extending in a direction parallel to one another. A movable, shaping tool is arranged to face the inside of the book casing spine to shape a web on the book casing spine with the aid of the two fold-shaping rails. The shaping tool includes two spaced-apart support bars that extend parallel to the fold-shaping rails and are arranged to be adjustable so that together they adjust the web width of the book casing spine in a direction transverse to the direction of extension of the fold-shaping rails.

A sheet processing apparatus which is capable of improving operability while suppressing an increase in apparatus size. In a front cover insertion mode, an insertion sheet for a front cover is inserted into a bundle of sheets on which images have been formed, and in a rear cover insertion mode, an insertion sheet for a rear cover is inserted into the bundle of sheets. Insertion sheets for the front cover and insertion sheets for the rear cover are set with the same orientation in a manual feed tray 105. An insertion sheet for the front cover stored in the manual feed tray 105 is conveyed to a finisher 500 in one of a face-down state and a face-up state. An insertion sheet for the rear cover stored in the manual feed tray 105 is conveyed to the finisher 500 in the other of the face-down state and the face-up state. The insertion sheets for the front cover and for the rear cover conveyed from the manual feed tray 105 and the sheets on which images have been formed are stacked on the finisher 500.

Methods for creating customized children's storybooks with fingerprint art using fingerprint-ready templates stored in association with a software application on a desktop computer, a tablet computer, or a smart phone. The methods include the use of preconfigured templates and prompted discussions that elicit responses from the child to create text for the storybook. The text may be generated by speech recognition software processing digital audio recordings of the child's responses. A digital image of the child's fingerprint is acquired and the fingerprint image and/or the storybook scenes are scaled to fit each other. Fingerprint-ready image templates are used to facilitate the creation of fingerprint art. A completed page image is formed by digitally inserting a fingerprint into the fingerprint-shaped area, and if desired, coloring the image or drawing a scene around the image. When the scenes are completed the software application compiles the book pages and prints the same.

A method and a device for pressing a book block over the rounded back of a book block having a longitudinal axis extending in the center and along the back. The book block is clamped between two clamping jaws of a clamping device, in a region adjacent to the back of the book block, parallel to the longitudinal axis of the back. A pressing device presses a pressing member against the back, wherein the pressing member is placed approximately in the center of the back onto the book block back. At least a section of the pressing member is then moved across the back. Once the pressing member, which is oriented parallel to the longitudinal axis of the back, is placed onto the back it then moves along at least one continuously preselected movement path over the back.

Safety apparatuses for objects having at least one nut are disclosed. Contemplated apparatuses comprise a base, one or more nut caps, and one or more electronic sensors configured to acquire data related to a corresponding nut, wheel or tire. In some embodiments, a physical nut rotation indicator that can readily be observed by an operator is included, and a retention wall disposed on the base can operate in conjunction with the physical nut rotation indicator to block a rotation of a nut. Apparatuses are preferably configured to remain stable in harsher environments.

A showerhead electrode is provided where backside inserts are positioned in backside recesses formed along the backside of the electrode. The backside inserts comprise a tool engaging portion. The tool engaging portion is formed such that the backside insert further comprises one or more lateral shielding portions between the tool engaging portion and the threaded outside diameter to prevent a tool engaged with the tool engaging portion of the backside insert from extending beyond the threaded outside diameter of the insert. Further, the tool engaging portion of the backside insert comprises a plurality of torque-receiving slots arranged about the axis of rotation of the backside insert. The torque-receiving slots are arranged to avoid on-axis rotation of the backside insert via opposing pairs of torque-receiving slots.

In a driving circuit, one output circuit has a scanning signal line, a first transistor which controls electrical connection between the scanning signal line and a clock signal line which has a gate connected to a first node, the first node which is at an active potential in a first time period including a time period during which the active potential is output to the scanning signal line, a second transistor which electrically connects the first node and an inactive signal line which has a potential to open the transistor in a second time period other than the first time period, and the second transistor has a gate connected to a second node, wherein the second node has two kinds of timings to be charged for retaining the active potential.

A stage circuit and a scan driver using the same that is capable of concurrently (e.g., simultaneously) or progressively supplying a scan signal to a plurality of scan lines. The stage circuit includes a progressive driver and a concurrent driver.

A wearable device has a carrier having an aperture. A device has a USB connection and a protrusion wherein the protrusion is received in the aperture to connect the device to a wristband. The device is a USB type device having athletic functionality. The device may further be configured to receive calibration data such that a measured distance may be converted to a known distance based on athletic activity performed by a user.

A display device including various portions, circuits and other arrangements for outputting various pulses and triggers, for controlling forward shift and backward shift operations.

An open loop clock divider circuit includes (a) a first divider configured to receive an incoming clock signal and output a first divided clock signal, (b) a flying-adder synthesizer configured to fractionally divide the first divided clock signal and output a fractionally divided clock signal, and (c) a second divider configured to receive the fractionally divided clock signal and output a second divided clock signal. The open loop clock divider circuit advantageously provides a fractional divider in which there is no feedback loop between the source frequency (fs) and the destination frequency (fd). Methods of generating a divided clock signal involving the open loop clock divider circuit are also disclosed.

A single wire serial interface for power ICs and other devices is provided. To use the interface, a device is configured to include an EN/SET input pin. A counter within the device counts clock pulses sent to the EN/SET input pin. The output of the counter is passed to a ROM or other decoder circuit. The ROM selects an operational state for the device that corresponds to the value of the counter. In this way, control states may be selected for the device by sending corresponding clock pulses to the EN/SET pin. Holding the EN/SET pin high causes the device to maintain its operational state. Holding the EN/SET pin low for a predetermined timeout period resets the counter and causes the device to adopt a predetermined configuration (such as off) until new clock pulses are received at the EN/SET pin.

A stage circuit including an output unit for supplying first or second power source to an output terminal is disclosed. The stage circuit may comprise a bidirectional driver for respectively supplying signals supplied to first and second input terminals, a first driver, and a second driver. The second driver controls the output unit to output the second power source to the output terminal without any voltage loss, corresponding to a second clock signal.

A bridge output circuit includes an output terminal, a high side transistor, a low side transistor, a high side driver for controlling a gate voltage of the high side transistor, a low side driver for controlling a gate voltage of the low side transistor, and a controller for controlling the high side and low side drivers. The low side driver includes a first current source, a second current source, and a first assist circuit. The controller is configured to control the turning-on and turning-off states of the first current source, the second current source and the first assist circuit.

The present invention relates to a method for downloading a binary configuration file in a programmable circuit implemented in a device. The device comprises at least one central processing unit, a plurality of connectors, and a programmable circuit enabling all or a part of the signals received by said connectors to be processed and transmitted to at least one other circuit of the device. The device analyzes the signals present on the connectors in order to define what other devices are connected and whether the connections are operational. Then, a configuration file is selected from among a set of configuration files according to the operational connections and is downloaded from a memory of the device into the programmable circuit. The invention also relates to a device having a component programmed according to the method previously described.

Embodiments of the invention are generally directed to a single-ended configurable multi-mode driver. An embodiment of an apparatus includes an input to receive an input signal, an output to transmit a driven signal generated from the input signal on a communication channel, a mechanism for independently configuring a termination resistance of the driver apparatus, and a mechanism for independently configuring a voltage swing of the driven signal without modifying a supply voltage for the apparatus.

A circuit for a single differential-inductor oscillator with common-mode resonance may include a tank circuit formed by coupling a first inductor with a pair of first capacitors; a cross-coupled transistor pair coupled to the tank circuit; and one or more second capacitors coupled to the tank circuit and the cross-coupled transistors. The single differential-inductor oscillator may be configured such that a common mode (CM) resonance frequency (FCM) associated with the single differential-inductor oscillator is at twice a differential resonance frequency (FD) associated with the single differential-inductor oscillator.

The invention concerns an oscillator generating a wave composed of a frequency of on the order of terahertz from a beat of two optical waves generated by a dual-frequency optical source. The oscillator includes a modulator the transfer function of which is non-linear for generating harmonics with a frequency of less than one terahertz for each of the optical waves generated by the dual-frequency optical source, an optical detector able to detect at least one harmonic for each of the optical waves generated by the dual-frequency optical source and transforming the harmonics detected into an electrical signal, a phase comparator for comparing the electrical signal with a reference electrical signal, and a module for controlling at least one element of the dual-frequency optical source with a signal obtained from the signal resulting from the comparison.

The present invention proposes a digital system and method of measuring (estimating) non-energy parameters of the signal (phase, frequency and frequency rate) received in additive mixture with Gaussian noise. The first embodiment of the measuring system consists of a PLL system tracking variable signal frequency, a block of NCO full phase computation (OFPC), a block of signal phase primary estimation (SPPE) and a first type adaptive filter filtering the signal from the output of SPPE. The second embodiment of the invention has no block SPPE, and NCO full phase is fed to the input of a second type adaptive filter. The present invention can be used in receivers of various navigation systems, such as GPS, GLONASS and GALILEO, which provide precise measurements of signal phase at different rates of frequency change, as well as systems using digital PLLs for speed measurements.

A method, an apparatus, and a computer program product are provided. The apparatus tunes a frequency provided by a VCO. The apparatus determines a relative capacitance change associated with a first frequency and a desired frequency from a look-up table. The apparatus adjusts a capacitor circuit in the VCO based on the determined relative capacitance change determined from the look-up table in order to tune from the first frequency to the desired frequency. The apparatus determines that the frequency provided by the VCO is a second frequency different than the desired frequency after adjusting the capacitor circuit. The apparatus performs an iterative search to further adjust the capacitor circuit when a difference between the second frequency and the desired frequency is greater than a threshold.

The invention provides a switching valve having a valve element which is movable in a housing, an actuating apparatus acting on the valve element in a first direction and a spring apparatus charging the valve element in a second direction. According to the invention, the first and second directions are in opposition and the spring apparatus has a progressive spring characteristic.

In a processing machine including a processor having a processing blade and a receiver having a reception member and in which a blade edge of the processing blade and a reception portion, of the reception member, engage with each other to process a paper sheet therebetween, the processing blade is one processing blade selected from a blade group and is attached to the processor so as to be changeable to another processing blade of the blade group, reception portions of kinds corresponding to a plurality of kinds of the processing blades of the blade group are formed on the reception member, and the processing blade attached to the processor is positioned so as to be in a position where the blade edge is engageable with the reception portion of the corresponding kind.

A method for operating a processing system, in which product units of different formats are processed. The processing system contains a plurality of processing devices that are arranged one after the other in a processing line. In the event of a format changeover, certain component arrangements arranged in the processing system must be adapted to the new product format. In the event of an upcoming format change, a gap in the conveyed goods is generated while the conveying operation is maintained, wherein the gap in the conveyed goods runs through the processing system along the processing devices. As soon as the gap in the conveyed goods runs through a component arrangement to be adapted to the new format, the format is changed over at the component arrangement while the gap in the conveyed goods runs through the component arrangement.

The invention proposes a method for producing a printed product, in which a printed product, preferably produced in a forme-bound high-capacity printing process, in the form of a main product (2) or a subproduct is provided with an identification means which comprises a piece of individualizable product-specific information. At least two downstream individualization steps are performed, wherein the identification means allow the piece of information which is to be added in the at least two further downstream individualization steps to be associated with the respective product. Preferably, the new addressee-specific digital printed product comprises blog articles, preferably in the form of a blog insert, which is in turn preferably produced using digital printing. Identification means, for example in the form of ID tags (4, 4'), comprise not only the product-specific identification information but preferably also control information (31-36) which can be read by sensors on the handling devices (7-12) and hence directly control the handling of the respective product by this at least one handling device (7-12) and, in cooperation with inspection codes on the subproducts to be supplied, allow the correct supply to be inspected. The present invention also allows uninterrupted compilation of product packages for postal dispatch by virtue of the product sequence in the course of the conveying line comprising, at least in sections, a recurring succession of a respective one or more intermediate products partly individualized on an addressee-specific basis and at least one, preferably a plurality of, non-individualized standard intermediate products.