Susan Gruber, Mark J. van der Laan.

Source: Statistical Science, Volume 34, Number 1, 82--85.

Abstract:
Dorie and co-authors (DHSSC) are to be congratulated for initiating the ACIC Data Challenge. Their project engaged the community and accelerated research by providing a level playing field for comparing the performance of a priori specified algorithms. DHSSC identified themes concerning characteristics of the DGP, properties of the estimators, and inference. We discuss these themes in the context of targeted learning.

Elizabeth A. Stuart

Source: Statist. Sci., Volume 25, Number 1, 1--21.

Abstract:
When estimating causal effects using observational data, it is desirable to replicate a randomized experiment as closely as possible by obtaining treated and control groups with similar covariate distributions. This goal can often be achieved by choosing well-matched samples of the original treated and control groups, thereby reducing bias due to the covariates. Since the 1970s, work on matching methods has examined how to best choose treated and control subjects for comparison. Matching methods are gaining popularity in fields such as economics, epidemiology, medicine and political science. However, until now the literature and related advice has been scattered across disciplines. Researchers who are interested in using matching methods—or developing methods related to matching—do not have a single place to turn to learn about past and current research. This paper provides a structure for thinking about matching methods and guidance on their use, coalescing the existing research (both old and new) and providing a summary of where the literature on matching methods is now and where it should be headed.

A prominent theory claims that the right temporoparietal junction (rTPJ) is especially associated with embodied processes relevant to perspective-taking. In the present study, we use high-definition transcranial direct current stimulation to provide evidence that the rTPJ is causally associated with the embodied processes underpinning perspective-taking. Eighty-eight young human adults were stratified to receive either rTPJ or dorsomedial PFC anodal high-definition transcranial direct current stimulation in a sham-controlled, double-blind, repeated-measures design. Perspective-tracking (line-of-sight) and perspective-taking (embodied rotation) were assessed using a visuo-spatial perspective-taking task that required understanding what another person could see or how they see it, respectively. Embodied processing was manipulated by positioning the participant in a manner congruent or incongruent with the orientation of an avatar on the screen. As perspective-taking, but not perspective-tracking, is influenced by bodily position, this allows the investigation of the specific causal role for the rTPJ in embodied processing. Crucially, anodal stimulation to the rTPJ increased the effect of bodily position during perspective-taking, whereas no such effects were identified during perspective-tracking, thereby providing evidence for a causal role for the rTPJ in the embodied component of perspective-taking. Stimulation to the dorsomedial PFC had no effect on perspective-tracking or taking. Therefore, the present study provides support for theories postulating that the rTPJ is causally involved in embodied cognitive processing relevant to social functioning.

SIGNIFICANCE STATEMENT The ability to understand another's perspective is a fundamental component of social functioning. Adopting another perspective is thought to involve both embodied and nonembodied processes. The present study used high-definition transcranial direct current stimulation (HD-tDCS) and provided causal evidence that the right temporoparietal junction is involved specifically in the embodied component of perspective-taking. Specifically, HD-tDCS to the right temporoparietal junction, but not another hub of the social brain (dorsomedial PFC), increased the effect of body position during perspective-taking, but not tracking. This is the first causal evidence that HD-tDCS can modulate social embodied processing in a site-specific and task-specific manner.

The superior colliculus (SC) is arguably the most important visual structure in the mouse brain and is well known for its involvement in innate responses to visual threats and prey items. In other species, the SC plays a central role in voluntary as well as innate visual functions, including crucial contributions to selective attention and perceptual decision-making. In the mouse, the possible role of the SC in voluntary visual choice behaviors has not been established. Here, we demonstrate that the mouse SC of both sexes plays a causal role in visual perceptual decision-making by transiently inhibiting SC activity during an orientation change detection task. First, unilateral SC inhibition-induced spatially specific deficits in detection. Hit rates were reduced, and reaction times increased for orientation changes in the contralateral but not ipsilateral visual field. Second, the deficits caused by SC inhibition were specific to a temporal epoch coincident with early visual burst responses in the SC. Inhibiting SC during this 100-ms period caused a contralateral detection deficit, whereas inhibition immediately before or after did not. Third, SC inhibition reduced visual detection sensitivity. Psychometric analysis revealed that inhibiting SC visual activity significantly increased detection thresholds for contralateral orientation changes. In addition, effects on detection thresholds and lapse rates caused by SC inhibition were larger in the presence of a competing visual stimulus, indicating a role for the mouse SC in visual target selection. Together, our results demonstrate that the mouse SC is necessary for the normal performance of voluntary visual choice behaviors.

SIGNIFICANCE STATEMENT The mouse superior colliculus (SC) has become a popular model for studying the circuit organization and development of the visual system. Although the SC is a fundamental component of the visual pathways in mice, its role in visual perceptual decision-making is not clear. By investigating how temporally precise SC inhibition influenced behavioral performance during a visually guided orientation change detection task, we identified a 100-ms temporal epoch of SC visual activity that is crucial for the ability of mice to detect behaviorally relevant visual changes. In addition, we found that SC inhibition also caused deficits in visual target selection. Thus, our findings highlight the importance of the SC for visual perceptual choice behavior in the mouse.

Ancient trees are disappearing from protected national forests around the world. A look inside $100 billion market for stolen wood

A firefly mating ritual turns into a synchronized light show

New research suggests the civilization used huge enclosures to trap and stockpile live fish to support its complex society

A new analysis of ancient ostrich eggs at the British Museum underscores the interconnectedness of the ancient world

The children's book author and illustrator purchased the repurposed World War II vessel in 1967

In April alone, the Sturminster Newton Mill ground more than one ton of wheat

The graphic designer is receiving a Lifetime Achievement Award from Cooper Hewitt for her recognizable computer icons, typefaces and graphics

CNA Staff, May 8, 2020 / 04:15 pm (CNA).- As parishes and dioceses across the country deal with a drop in collections and the prospects of layoffs amid the pandemic, many parishes have managed to avail themselves of government loans designed to cover eight weeks of payroll expenses.

CBS News reported Friday that an estimated 12,000-13,000 of the 17,000 Catholic parishes in the U.S. had applied for Paycheck Protection Program (PPP) payroll loans from the Small Business Administration (SBA), and 9,000 so far had received them.

Guidance from the SBA on eligibility for the loans states that “no otherwise eligible organization will be disqualified from receiving a loan because of the religious nature, religious identity, or religious speech of the organization.”

Religious organizations are eligible for the loans as long as they meet the requirements of Section 501(c)(3) nonprofit and employ 500 or fewer people, the SBA said.

“The PPP isn't about the federal government assisting houses of worship or churches,” Pat Markey, the executive director of the Diocesan Fiscal Management Conference, told CBS News.

“PPP is about keeping people on payrolls, and a large segment of our society [in] the not for profit world...are churches and houses of worship. And they have people on payrolls too. So, if what this is about is keeping people on payrolls, then we all should have availability to do that.”

The Diocesan Fiscal Management Conference did not reply by press time to CNA’s request for additional comment.

Congress passed the Coronavirus Aid, Relief, and Economic Security (CARES) Act March 27 to help relieve the economy during the coronavirus pandemic.

The CARES Act initially authorized some $350 billion in loans to small businesses, intended to allow them to continue to pay their employees. The loans were given on a first come, first serve basis.

The second round of funding, with some $310 billion in additional funds available, began April 27.

The loans were capped at $10 million, were open to businesses with fewer than 500 employees per location, and were intended to cover two months of payroll costs.

The federal government promised to forgive the loans if a business used at least 75% of the funds to maintain its payroll at “pre-pandemic levels” for eight weeks after the loan is disbursed, the New York Times reports.

The remaining money could be used only to pay for certain expenses, such as a mortgage, rent, and utilities, according to the Times.

A survey of Protestant pastors by LifeWay Research found that about 40% had applied for PPP loans with more than half of them reporting being approved.

NPR reports that synagogues have also applied for government funding, though in a smaller proportion— of nearly 4,000 synagogues in the United States, about 250 were approved for PPP loans in the first round of lending, according to surveys by the Jewish Federations of North America and the Union of Orthodox Jewish Congregations of America.

The PPP has been subject to some criticism since its launch, including from those who say business owners with criminal records have been excluded from the program thus far.

In addition, several large companies, such as Ruth’s Chris Steakhouse, have received multi-million dollar loans through the program. Some of these large companies, such as Shake Shack, have since returned their loans.

Two New York dioceses— Rochester and Buffalo— are suing the Small Business Administration for access to PPP funds, after they were denied loans because of their bankruptcy status.

An SBA rule stipulated that the funds would not go to bankruptcy debtors. Both the dioceses of Rochester and Buffalo have filed for bankruptcy in the past several months, after being named in hundreds of clergy sex abuse lawsuits filed under New York Child Victims Protection Act.

 

German translation of the BIS Press Release on the presentation of the Annual Report (25 June 2017)

An Israeli Jew comes to faith in Jesus through the witness of an OM worker.

God gets all the glory for the great things He has done through OM the past 50 years. Everyone is looking forward to the next 50 in great anticipation.

After hearing about God as a child, Ania reconnected with OM ten years later to learn more and share the truth with her family.

CNA Staff, May 8, 2020 / 04:15 pm (CNA).- As parishes and dioceses across the country deal with a drop in collections and the prospects of layoffs amid the pandemic, many parishes have managed to avail themselves of government loans designed to cover eight weeks of payroll expenses.

CBS News reported Friday that an estimated 12,000-13,000 of the 17,000 Catholic parishes in the U.S. had applied for Paycheck Protection Program (PPP) payroll loans from the Small Business Administration (SBA), and 9,000 so far had received them.

Guidance from the SBA on eligibility for the loans states that “no otherwise eligible organization will be disqualified from receiving a loan because of the religious nature, religious identity, or religious speech of the organization.”

Religious organizations are eligible for the loans as long as they meet the requirements of Section 501(c)(3) nonprofit and employ 500 or fewer people, the SBA said.

“The PPP isn't about the federal government assisting houses of worship or churches,” Pat Markey, the executive director of the Diocesan Fiscal Management Conference, told CBS News.

“PPP is about keeping people on payrolls, and a large segment of our society [in] the not for profit world...are churches and houses of worship. And they have people on payrolls too. So, if what this is about is keeping people on payrolls, then we all should have availability to do that.”

The Diocesan Fiscal Management Conference did not reply by press time to CNA’s request for additional comment.

Congress passed the Coronavirus Aid, Relief, and Economic Security (CARES) Act March 27 to help relieve the economy during the coronavirus pandemic.

The CARES Act initially authorized some $350 billion in loans to small businesses, intended to allow them to continue to pay their employees. The loans were given on a first come, first serve basis.

The second round of funding, with some $310 billion in additional funds available, began April 27.

The loans were capped at $10 million, were open to businesses with fewer than 500 employees per location, and were intended to cover two months of payroll costs.

The federal government promised to forgive the loans if a business used at least 75% of the funds to maintain its payroll at “pre-pandemic levels” for eight weeks after the loan is disbursed, the New York Times reports.

The remaining money could be used only to pay for certain expenses, such as a mortgage, rent, and utilities, according to the Times.

A survey of Protestant pastors by LifeWay Research found that about 40% had applied for PPP loans with more than half of them reporting being approved.

NPR reports that synagogues have also applied for government funding, though in a smaller proportion— of nearly 4,000 synagogues in the United States, about 250 were approved for PPP loans in the first round of lending, according to surveys by the Jewish Federations of North America and the Union of Orthodox Jewish Congregations of America.

The PPP has been subject to some criticism since its launch, including from those who say business owners with criminal records have been excluded from the program thus far.

In addition, several large companies, such as Ruth’s Chris Steakhouse, have received multi-million dollar loans through the program. Some of these large companies, such as Shake Shack, have since returned their loans.

Two New York dioceses— Rochester and Buffalo— are suing the Small Business Administration for access to PPP funds, after they were denied loans because of their bankruptcy status.

An SBA rule stipulated that the funds would not go to bankruptcy debtors. Both the dioceses of Rochester and Buffalo have filed for bankruptcy in the past several months, after being named in hundreds of clergy sex abuse lawsuits filed under New York Child Victims Protection Act.

 

OM Ireland's two multi-media puppet shows perform over 75 times in schools around Ireland. The gospel message is expected to be heard by thousands.

A Thousand Moons

THE news earlier this week that Tennis Scotland will be on the receiving end of a £12 million package from the Lawn Tennis Association (LTA) is hugely significant.

This typical dish from Puglia, the region in the south east of Italy where you see the beautiful white trulli houses in the holiday brochures, is one of our customers’ favourite dishes from the menu in our Valvona & Crolla Caffè Bar in Edinburgh.

USA Gymnastics, which develops the U.S. Olympic team, reportedly failed to inform authorities of numerous allegations regarding sexual abuse by coaches.

At age 17, Nick D'Aloisio just sold Summly to Yahoo! for $30 Million. With technology increasingly penetrating our everyday lives, today's children grow up with computers in their blood: thus, this rise of the teenage entrepreneur is not fading anytime soon.

Although obesity is correlated with levels of systolic and diastolic blood pressure, there is little evidence if the increases in obesity over the last 40 years have resulted in increased blood pressure levels.

Despite increases in obesity in Bogalusa, Louisiana between 1974 and 1993, there was no increase in systolic or diastolic blood pressure levels. It should not be assumed that trends in high blood pressure have paralleled those for obesity. (Read the full article)

Vitamin K prophylaxis at birth is an effective intervention for preventing vitamin K deficiency bleeding.

Refusal of vitamin K is not common, but those who refuse are more likely to have a birth attended by a midwife, and deliver at home or in a birth center. They are also less likely to immunize their child. (Read the full article)

Parent refusal and delay of childhood vaccines has increased in recent years and is believed to cluster in communities. Such clustering could pose public health risks and barriers to achieving quality benchmarks for immunization coverage.

We found that underimmunization and vaccine refusal cluster geographically. Spatial scan analysis may be a useful tool to identify locations where clinicians may face challenges to achieving benchmarks for immunization coverage and that deserve special focus for interventions. (Read the full article)

Microsoft's new write-once storage medium is constructed from quartz glass, stores data using lasers, and uses machine learning algorithms for decoding.

Partick Thistle have released, in full, a letter sent by the club to SPFL chiefs following the news that league reconstruction has been scrapped - confirming the Jags' relegation.

David S. Freedman
Jun 1, 1999; 103:1175-1182
ARTICLES

On Friday, USA Swimming CEO Chuck Wielgus offered a formal apology for not doing more to prevent sexual abuse by coaches.

CNA Staff, Apr 6, 2020 / 01:00 pm (CNA).- Unable to lead the traditional Palm Sunday procession through Jerusalem, Archbishop Pierbattista Pizzaballa, OFM, apostolic administrator of the Latin Patriarchate of Jerusalem, blessed the city with a relic of the True Cross on April 5.

The annual procession, which recalls Christ’s entry into the city and the beginning of Holy Week, was cancelled in line with international efforts to curb the spread of COVID-19, with public gatherings and events suspended in Israel. 

“We decided since we cannot have the palm procession, to have anyway a moment of prayer this afternoon,” said Pizzaballa on Sunday. The archbishop led a short, multi-lingual “moment of prayer” at Dominus Flevit, a church located on the Mount of Olives.

The church, which is shaped like a teardrop, overlooks the city, and was built to mark the Gospel account of Jesus weeping as he envisioned the destruction of Jerusalem.

The prayer service ended with Pizzaballa raising a relic of the True Cross over the city in benediction. 

Jerusalem, said Pizzaballa, “is a symbol of the church, the symbol also of humanity. It is the house of prayer for all the people, according to the scriptures.”

“So when we cry [over] Jerusalem, together with Jesus, we cry [over] all our human fraternity, for this difficult moment we are living, for this sad Palm Sunday, this Easter we have to celebrate.”

Pizzaballa said that sadness over being unable to celebrate the liturgical feasts of Holy Week is real, but “maybe, in a way also very true, very essential.” 

“Today we have not celebrated the solemn and beautiful entrance of Jesus to the city of Jerusalem like every year, with faithful from all the parishes of the diocese and with pilgrims from all over the world,” Pizzaballa said during the prayer service.

“We have not raised our palms and olive branches to cry out ‘Hosanna’ to our king, Jesus the Christ.” 

Instead, the archbishop asked Catholics in the Holy Land and around the world to consider what the Lord may be trying to say during these times.

He noted that, while the people of Jerusalem in the Gospel greeted him with cheers on Palm Sunday, Jesus knew that “He came to Jerusalem, not to be on the throne like David, but to be put to death.” 

“The meaning that Jesus attributes to his ‘triumphal entry’ is different from the meaning that the people of Jerusalem saw in it,” he said.

“Perhaps this is the lesson that Jesus wants to teach us today. We turn to God when there is something that harms us. When we are in trouble, suddenly we all want to ask big and difficult questions.”

While people may be praying for an end to the COVID-19 pandemic as we often do for solutions  to other problems, the archbishop said that  “Jesus responds in His own way” to these prayers. 

“Precisely because Jesus says ‘yes’ to our deepest desires, He will have to say ‘no’ to our immediate desires,” he said.

Drawing comparisons between this year's Palm Sunday and the biblical Palm Sunday during Christ's earthly life, Pizzaballa said the story of Jesus’ entrance into Jerusalem “is a lesson on the discrepancy between our expectations and God’s response.” 

The crowd who greeted Jesus was disappointed that their salvation was not immediate, said Pizzaballa, but “Jesus’ entry into Jerusalem is truly the moment when salvation is born.” 

“The ‘Hosannas’ were justified, even if not for the reasons the Jerusalemites had supposed,” he said. 

This remains true today, he explained. Although it may seem as though God is not answering prayers and leaves people “disappointed,” this is in part because “our expectations remain without an apparent response.”

Christianity, he said, “is based on hope and love, not certainty,” and that while God will not answer all problems with certainty, “He won’t leave us alone.” 

“And here, today, despite everything, at the gates of His and our city, we declare that we really want to welcome Him as our King and Messiah, and to follow Him on His way to His throne, the cross,” he said.  

“But we also ask Him to give us the strength necessary to carry it with His own, fruitful love.”

The West Bengal government has agreed to allow eight trains to bring migrants home from four states, the Railway Ministry tweeted today. It said Bengal had until now allowed only two "Shramik"...

The US Air Force and Dover Air Force Base have notified Delaware’s Department of Natural Resources and Environmental Control and Division of Public Health, that four wells near the base sampled by the federal government for perfluoroalkyl substances (PFAS), including perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), have returned elevated levels of PFOS and PFOA above the US Environmental Protection Agency’s health advisory for these substances of 70 parts per trillion (ppt).

While for the latter the companies, including Vodafone Idea, have sought the facility to pay in installments spread over some 20 years which is currently before the SC, there's been no such demand for current payments.

Para los residentes de Delaware, este no es momento de ser complacientes. A partir de las 8:00 a.m. del martes, 28 de abril, los residentes de Delaware deberán usar mascarilla en lugares públicos, incluidos mercados, tiendas, farmacias, consultorios médicos y medios de transporte público. La situación que enfrentamos es muy grave, con nuevos casos de […]

Credit and Finance for MSMEs: MSME Ministry on Thursday announced an MoU between the Coir Board and IIT Madras for setting up a Centre of Excellence to boost the use of coir “exclusively or in combination with other natural fibres".

The Xiaomi Redmi Note 7 Pro is a big upgrade from its predecessor with a 48MP camera and a powerful mid-range chipset tuned for gaming, but is it best mid-range phone to buy right now? Watch our review to find out.

The study of National Association of Foreign Student Advisers has the opinion that global students made a contribution of $39 billion to the US economy in the academic year of 2017-2018.The studyMoreover, it found that the economic activity of overseas…

Owing to the strict interpretations of rules which govern the H-1B work visa program Indian IT companies, as well as their customers, face a shortage of mid-level talent in the US.A major problemThere was a problem of talent at the entry-level in the…

A merit-based immigration plan being put together by Jared Kushner, White House senior adviser it could lead to an escalation in US visas for extremely skilled workers, sources revealed on 24 Apr 2019.Merit-based Immigration ProposalKushner is assumed…

US lawmakers are casting their vote regarding lifting the country-cap of seven percent for issuing the Green Card. This is a move that will immensely benefit top skilled Indian IT professionals who are languishing in the queue for several years. The…

A new announcement by the USA Administration amounts to a concentrated effort by the administration to alter the legal immigration and focus on the legal ways for immigration.The rule denotes that the applicants for Green Card and visa will be viewed…

Govt of India has issued a strict warning against Zoom app, which has become India’s most downloaded app for March, even beating the likes of Whatsapp and Facebook, TikTok. Govt has issued guidelines on how to use this app, but more importantly, suggested not to use it. Govt of India: Zoom Is Unsafe After National […]

The post Govt Issues Strict Warning Against Zoom App; Says It’s ‘Not Safe’, Issues Guidelines Of Usage first appeared on Trak.in . Trak.in Mobile Apps: Android | iOS.

Other tools allow a sanity check of placement density vs available board space.  There is an older post "Skill code to evaluate all components area (Accumulative Place bound area)"  (9 years ago) that has a couple of examples that no longer work or expired.

This would be useful to provide feedback to schismatic and project managers regarding the component density on the PCB and how it will affect the routing abilities.  Thermal considerations can be evaluated as well 

Has anyone attempted this or still being done externally in spread sheets?

અમેરિકાની મેનેસૅટા યૂનિવર્સિટીના ચેપીરોગો વિશેના સંશોધનકારોના નવા અભ્યાસથી ખળભળાટ

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