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MedSolace Inc. Released a Novel COVID-19 Calculator That Estimates Users' Outcomes and Tracks Their Symptoms

The app stratifies users as high, moderate or low risk based on their complication rate from a potential COVID-19 infection.




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First-of-its-Kind Blood Test Can Detect Over 50 Kinds of Cancer—Often Before Symptoms Even Show

The test was able to predict the tissue in which the cancer originated in 96% of samples; not only that, it was accurate for 93%.

The post First-of-its-Kind Blood Test Can Detect Over 50 Kinds of Cancer—Often Before Symptoms Even Show appeared first on Good News Network.




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As Coal Usage Declines, New Study Finds Dramatic Decrease in Asthma Symptoms and Hospitalizations

According to research conducted around four coal-powered plants in Louisville, Kentucky, retiring coal has a noticeable effect on people's health.

The post As Coal Usage Declines, New Study Finds Dramatic Decrease in Asthma Symptoms and Hospitalizations appeared first on Good News Network.




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American Heart Association urges patients to quickly call 911 for chest pain or heart symptoms

Circulation Journal Report AHA COVID-19 Newsroom   FOR IMMEDIATE RELEASE: 4 a.m. CT/5 a.m. ET, Saturday, May 2, 2020   DALLAS, May 2, 2020 — American Heart Association volunteer experts issued Temporary Emergency Guidance to STEMI Systems of Care...




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Kids with Kawasaki disease symptoms possibly linked to COVID-19; coronavirus infection leading to critical illness in children remains very infrequent




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12 symptoms of a back-to-front design process

Everyday consumer products continue to frustrate people. The failure of companies to fully embrace UX is partly to blame, but there is also another reason -- one that is seldom discussed. Consumer product companies pay too much heed to their retail customers and, in so doing, they prevent the development team from getting first-hand knowledge of end users.




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Joint Prediction and Time Estimation of COVID-19 Developing Severe Symptoms using Chest CT Scan. (arXiv:2005.03405v1 [eess.IV])

With the rapidly worldwide spread of Coronavirus disease (COVID-19), it is of great importance to conduct early diagnosis of COVID-19 and predict the time that patients might convert to the severe stage, for designing effective treatment plan and reducing the clinicians' workloads. In this study, we propose a joint classification and regression method to determine whether the patient would develop severe symptoms in the later time, and if yes, predict the possible conversion time that the patient would spend to convert to the severe stage. To do this, the proposed method takes into account 1) the weight for each sample to reduce the outliers' influence and explore the problem of imbalance classification, and 2) the weight for each feature via a sparsity regularization term to remove the redundant features of high-dimensional data and learn the shared information across the classification task and the regression task. To our knowledge, this study is the first work to predict the disease progression and the conversion time, which could help clinicians to deal with the potential severe cases in time or even save the patients' lives. Experimental analysis was conducted on a real data set from two hospitals with 422 chest computed tomography (CT) scans, where 52 cases were converted to severe on average 5.64 days and 34 cases were severe at admission. Results show that our method achieves the best classification (e.g., 85.91% of accuracy) and regression (e.g., 0.462 of the correlation coefficient) performance, compared to all comparison methods. Moreover, our proposed method yields 76.97% of accuracy for predicting the severe cases, 0.524 of the correlation coefficient, and 0.55 days difference for the converted time.




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Evaluating text coherence based on the graph of the consistency of phrases to identify symptoms of schizophrenia. (arXiv:2005.03008v1 [cs.CL])

Different state-of-the-art methods of the detection of schizophrenia symptoms based on the estimation of text coherence have been analyzed. The analysis of a text at the level of phrases has been suggested. The method based on the graph of the consistency of phrases has been proposed to evaluate the semantic coherence and the cohesion of a text. The semantic coherence, cohesion, and other linguistic features (lexical diversity, lexical density) have been taken into account to form feature vectors for the training of a model-classifier. The training of the classifier has been performed on the set of English-language interviews. According to the retrieved results, the impact of each feature on the output of the model has been analyzed. The results obtained can indicate that the proposed method based on the graph of the consistency of phrases may be used in the different tasks of the detection of mental illness.




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Very, very mild: Covid-19 symptoms and illness classification

What does 'mild' mean in the context of Covid-19? Geographer Felicity Callard details the multifarious meanings of mildness in this pandemic; how the term is used by different actors and what it comes to mean to those experiencing 'mild' cases. The mild, Callard argues,

will likely continue to be used for multiple Covid-19 purposes – whether adjudicating clinical symptoms, assessing the virus's impact on the body, determining the need for formal healthcare services, or judging the likely time of return to functional normality, whether inside and outside the labour market. I therefore predict on-going epistemological, ontological and political contestation over the scope and definition of the mild.




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Kemp: All Georgians, Regardless Of Symptoms, Should Use COVID-19 Screening App

Gov. Brian Kemp is encouraging all Georgians to undergo screening for the coronavirus as the testing supply continues to rise and the federal government plans to send enough swabs to test 2% of the state’s population. Speaking at the Capitol Thursday, Kemp said the change in guidance from the Centers for Disease Control and Prevention means those without symptoms can contact their doctor, local health department or use a free app from Augusta University to start the process.




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More than 250 people in Washington hospitalized last week with coronavirus symptoms; state data shows upward trend


Hospital admissions tracked by the state Department of Health offer a window into the pandemic's impact on the health care system. Right now, officials are not seeing a surge of patients, but worry one could still be coming.




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Brain Hub discusses motion sickness and symptoms of little-known disease Mal de Debarquement Syndrome

Do you suffer from an indescribable feeling of vertigo, constant dizziness and motion sickness? Chances are you could have Mal de Debarquement Syndrome.




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NYC schoolteacher self-quarantined with coronavirus symptoms, as city examines virus response

The teacher recently traveled to Italy and came back to class before noticing the symptoms, according to a source familiar with the situation.




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Lakers clear quarantine; no players have coronavirus symptoms

Having finished home quarantine, the Lakers announced no players have coronavirus symptoms.




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Former USC football player Quinton Powell hospitalized with COVID-19 symptoms

Former USC linebacker Quinton Powell is pleading for others to stay safe after being hospitalized while experiencing symptoms of the coronavirus illness.




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No Kings or Ducks players have reported or shown symptoms of coronavirus, the teams say

Kings and Ducks players have not shown any coronavirus symptoms after an Ottawa Senators player tested positive and played both teams before NHL suspended operations.




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California becomes first state to recommend coronavirus tests for some without symptoms

California is now giving coronavirus testing priority to asymptomatic people in high-risk settings such as nursing homes and prisons.




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Cancer symptoms: The colour patch on your tongue that could signal a form of cancer



CANCER be tricky to detect because you may not experience any symptoms in the initial stages and when you do, they can be confused with more benign conditions. An easily overlooked sign of cancer is a colour patch on your tongue.




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Avon Schools close through March 20 after second student shows symptoms of the coronavirus

All Avon schools will close through March 20 as one student has tested positive and a second student is showing symptoms of the novel coronavirus.

      




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Pacers waiting for symptoms before having players tested for coronavirus

The Pacers final game before the NBA went on hiatus was vs. the Celtics, whose player Marcus Smart has tested positive for the coronavirus

      




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Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease.

Inês Magro dos Reis
Apr 14, 2020; 0:jlr.RA120000632v1-jlr.RA120000632
Research Articles




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Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease. [Research Articles]

Niemann–Pick type C1 (NPC1) disease is a rare genetic condition in which the function of the lysosomal cholesterol transporter NPC1 protein is impaired. Consequently, sphingolipids and cholesterol accumulate in lysosomes of all tissues, triggering a cascade of pathological events that culminate in severe systemic and neurological symptoms. Lysosomal cholesterol accumulation is also a key-factor in the development of atherosclerosis and non-alcoholic steatohepatitis (NASH). In these two metabolic diseases, the administration of plant stanol esters has been shown to ameliorate cellular cholesterol accumulation and inflammation. Given the overlap of pathological mechanisms among atherosclerosis, NASH and NPC1 disease, we sought to investigate whether dietary supplementation with plant stanol esters improves the peripheral features of NPC1 disease. To this end, we used an NPC1 murine model featuring an Npc1 null allele (Npc1nih), creating a dysfunctional NPC1 protein. Npc1nih mice were fed a two or six percent plant stanol esters–enriched diet over the course of 5 weeks. During this period, hepatic and blood lipid and inflammatory profiles were assessed. Npc1nih mice fed the plant stanol–enriched diet exhibited lower hepatic cholesterol accumulation, damage and inflammation than regular chow–fed Npc1nih mice. Moreover, plant stanol consumption shifted circulating T-cells and monocytes in particular towards an anti-inflammatory profile. Overall, these effects were stronger following dietary supplementation with 6% stanols, suggesting a dose-dependent effect. The findings of our study highlight the potential use of plant stanols as an affordable complementary means to ameliorate disorders in hepatic and blood lipid metabolism and reduce inflammation in NPC1 disease.




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Cognitive symptoms of Alzheimer’s disease: clinical management and prevention




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Stroke: “striking reductions” are seen in number of people with symptoms seeking help




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Helping patients with medically unexplained symptoms

Persistent physical symptoms are common and include those symptoms that last at least three months and are insufficiently explained by a medical condition after adequate examination and investigation. Observational studies in primary care report that women, especially those aged 35-45 years, more commonly present with these symptoms. In this...




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Nasal symptoms of the common cold

The common cold is usually mild and self limiting - but they’re very annoying, especially the runny nose and bunged up feeling that form the nasal symptoms. A new practice article, published on BMJ.com looks at the available evidence for treatment of those nasal symptoms - both pharmacological and alternative. In this podcast we're joined by...




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Talk Evidence Covid-19 update - Confused symptoms, fatality rate uncertainty, Iceland's testing

For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give...




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Constitutional symptoms in a young person




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Depressive Symptoms in Children and Adolescents With Type 1 Diabetes: Association with diabetes-specific characteristics

Korey K. Hood
Jun 1, 2006; 29:1389-1389
BR Epidemiology/Health Services/Psychosocial Research




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CDC reminds clinicians to use standard precautions, recommends isolating patients with coronavirus symptoms

In light of the “emerging, rapidly evolving” outbreak of the novel coronavirus 2019-nCoV, the Centers for Disease Control and Prevention is reminding clinicians to use standard precautions consistently and advising they isolate patients who show signs and symptoms of the virus.




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Blood clots, skin lesions among newly identified possible COVID-19 symptoms

Blood clots, skin rashes and other lesions might be among the symptoms some people experience with COVID-19, according to new research released Thursday.




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Diabetes : its causes, symptoms, and treatment / by Charles W. Purdy.

London : Philadelphia, 1890.




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Diet and cholera : showing the vital importance of wholesome diet, and that its impurities and deficiencies are the chief cause of cholera, with its premonitory symptoms and treatment : in a series of letters, originally intended for insertion in the &quo

London : S. Highley, 1848.




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Diseases of women, including their pathology, causation, symptoms, diagnosis and treatment : a manual for students and practitioners / by Arthur W. Edis.

London : Smith, Elder, 1881.




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Dr. Buchans Domestic medicine; or a treatise on the prevention and cure of diseases, by regimen and simple medicines. To which is added, characteristic symptoms of diseases, from the nosology of the late celebrated Dr. Cullen of Edinburgh. With an appendi

Newcastle : printed by K. Anderson, 1812.




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An enquiry into the source from whence the symptoms of the scurvy and of putrid fevers, arise : and into the seat which those affections occupy in the animal oeconomy; with a view of ascertaining a more just idea of putrid diseases than has generally been

London : printed for J. Dodsley, 1782.




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Epidemic ophthalmia, its symptoms, diagnosis, and management : with papers upon allied subjects / by Sydney Stephenson.

Edinburgh : Young J. Pentland, 1895.




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Epilepsy : its symptoms, treatment, and relation to other chronic convulsive diseases / by J. Russell Reynolds.

London : J. Churchill, 1861.




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Air Pollution May Make COVID-19 Symptoms Worse

Research linking air pollution to elevated death rates remains preliminary but scientists hope the pandemic spurs tighter air quality regulations




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Saskatoon woman with COVID-19-like symptoms says it took 5 days to get tested after referral



  • News/Canada/Saskatoon

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Customers of Kamloops pharmacy asked to isolate, monitor for COVID-19 symptoms

Interior Health officials are asking people who went to the Save-On-Foods pharmacy in Columbia Place Shopping Centre in Kamloops, March 10, 13 and 14 along with March 16 to 21 to self-isolate following a positive case of COVID-19 at the store.



  • News/Canada/British Columbia

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Coronavirus: Dumbarton police station temporarily closed after staff member showed symptoms

Dumbarton police station has temporarily closed after a member of staff showed symptoms of Covid-19.




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Symptoms and Time to Medical Care in Children With Accidental Extremity Fractures

A delay in seeking medical care for children with significant injury often raises a concern about child abuse, but there are few data describing the range of responses children display after accidental fracture for providers to use in comparison.

This study presents the range of responses exhibited by children after accidental fractures and identifies factors associated with a delay in seeking medical care. No child was asymptomatic, although a minority did not manifest all expected responses after their injury. (Read the full article)




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Family-centered Program Deters Substance Use, Conduct Problems, and Depressive Symptoms in Black Adolescents

Conduct problems, substance use, substance use problems, and depressive symptoms increase as black adolescents enter high school. Although family-centered prevention programs deter these problems during middle school, no such programs have been developed and evaluated for black high school students.

This study demonstrates that participation in a family-centered preventive intervention reduces conduct problems, substance use, and substance use problems among black adolescents by more than 30% compared with adolescents in an attention control condition across nearly 2 years. (Read the full article)




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Impact of Maternal Depressive Symptoms on Growth of Preschool- and School-Aged Children

Few longitudinal studies from developing countries have assessed the relation between early maternal depressive symptoms and child growth beyond age 2. The results of these studies have been inconclusive.

Early maternal depressive symptoms were related to higher odds of deficits in stature but not to deficits in weight among preschool- and school-aged children. Well-child care provides opportunities to identify maternal depressive symptoms to prevent future child growth delays. (Read the full article)




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Depressive Symptoms and Neurocardiogenic Syncope in Children: A 2-Year Prospective Study

Adult patients with neurocardiogenic syncope have shown high rates of depression. Patients with more severe depressive symptoms have higher rates of syncope recurrence. Psychiatric interventions improve quality of life and decrease syncope recurrence rates.

Children with neurocargiogenic syncope presented a 2.6-fold higher rate of clinically significant depressive symptoms compared to healthy controls. No recurrent syncope was noted during follow-up which along with improvement in family functioning predicted depressive symptoms improvement. (Read the full article)




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Fish Consumption in Infancy and Asthma-like Symptoms at Preschool Age

Several studies have reported inverse associations between fish consumption during pregnancy or later childhood and asthma prevalence. However, because fish can also be highly allergenic, the optimal timing of introduction of fish and the adequate amount in infancy remains unclear.

Introduction of fish between 6 and 12 months but not fish consumption afterward is associated with a lower risk of wheezing whereas no introduction of fish or introduction between 0 and 6 months of life increases the risk of wheezing. (Read the full article)




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Symptoms and Otoscopic Signs in Bilateral and Unilateral Acute Otitis Media

Bilateral acute otitis media (AOM) is considered more severe than unilateral AOM, and several guidelines recommend more active management of bilateral AOM. However, severity of symptoms and otoscopic signs of bilateral and unilateral AOM have previously not been comprehensively studied.

Bilateral AOM seems to be clinically only a slightly more severe illness than unilateral AOM. When assessing AOM severity, bilaterality should not be used as a determining criterion; instead, the child’s symptoms together with otoscopic signs should also be acknowledged. (Read the full article)




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School Environment and Adolescent Depressive Symptoms: A Multilevel Longitudinal Study

Research indicates that adolescents who perceive their school to have a positive socioeducational environment are at reduced risk of developing depressive symptoms. However, there is limited evidence that school environments can influence adolescent emotional health independently from individual perceptions.

This multilevel longitudinal study shows that better school socioeducational environments, as assessed at the school level, reduce the prospective risk of depressive symptoms in adolescents. This association is shown to be independent from confounders and stronger in girls than boys. (Read the full article)




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Inconsolable Infant Crying and Maternal Postpartum Depressive Symptoms

Studies reveal that mothers of infants with colic (defined by Wessel’s criteria of >3 hours per day of distress) are more likely to develop depression. No studies have examined whether the consolability of infant crying predicts maternal depression risk.

Prolonged inconsolable infant crying has a stronger association with maternal depressive symptoms than overall daily duration of fussing and crying, suggesting that a mother’s report of inability to soothe her infant may be a powerful indicator of her depression risk. (Read the full article)