VOLUME 295 (2020) PAGES 3285–3300An incorrect graph was used in Fig. 5C. This error has now been corrected. Additionally, some of the statistics reported in the legend and text referring to Fig. 5C were incorrect. The F statistics for Fig. 5C should state Fken(3,16) = 7.454, p < 0.01; FCCCP(1,16) = 102.9, p < 0.0001; Finteraction(3,16) = 7.480, p < 0.01. This correction does not affect the results or conclusions of this work.jbc;295/17/5835/F5F1F5Figure 5C.

Noncitizens have long served in the U.S. military, often encouraged by the promise of a fast track to U.S. citizenship. In recent years, however, Congress and the Defense Department have made it more difficult for noncitizens to enlist. This brief give context to these policy changes and explores ways the military could better balance concerns about national security and the need for recruits with key cultural and professional skills.

Representatives from school districts, state education agencies, and institutions of higher education in Idaho convene to discuss teacher recruitment and retention.

Knowledge about objects encompasses not only their prototypical features but also complex, atypical, semantic knowledge (e.g., "Pizza was invented in Naples"). This fMRI study of male and female human participants combines univariate and multivariate analyses to consider the cortical representation of this more complex semantic knowledge. Using the categories of food, people, and places, this study investigates whether access to spatially related geographic semantic knowledge (1) involves the same domain-selective neural representations involved in access to prototypical taste knowledge about food; and (2) elicits activation of neural representations classically linked to places when this geographic knowledge is accessed about food and people. In three experiments using word stimuli, domain-relevant and atypical conceptual access for the categories food, people, and places were assessed. Results uncover two principles of semantic representation: food-selective representations in the left insula continue to be recruited when prototypical taste knowledge is task-irrelevant and under conditions of high cognitive demand; access to geographic knowledge for food and people categories involves the additional recruitment of classically place-selective parahippocampal gyrus, retrosplenial complex, and transverse occipital sulcus. These findings underscore the importance of object category in the representation of a broad range of knowledge, while showing how the cross recruitment of specialized representations may endow the considerable flexibility of our complex semantic knowledge.

SIGNIFICANCE STATEMENT We know not only stereotypical things about objects (an apple is round, graspable, edible) but can also flexibly combine typical and atypical features to form complex concepts (the metaphorical role an apple plays in Judeo-Christian belief). In this fMRI study, we observe that, when atypical geographic knowledge is accessed about food dishes, domain-selective sensorimotor-related cortical representations continue to be recruited, but that regions classically associated with place perception are additionally engaged. This interplay between categorically driven representations, linked to the object being accessed, and the flexible recruitment of semantic stores linked to the content being accessed, provides a potential mechanism for the broad representational repertoire of our semantic system.

The National Children's Study, a large-scale, longitudinal, birth cohort study of US children that endeavors to identify preventable and environmental origins of chronic diseases, has begun recruitment.

In a highly diverse, urban setting, pregnant women can be recruited to participate in the National Children's Study at rates similar to those obtained in clinic settings. Refinements to the pregnancy screener and other components are needed to optimize implementation. (Read the full article)

Pediatric primary care has undergone a cultural shift. Changes in electronic health records, certification requirements, and practice structure have left many physicians feeling too busy to participate in research. Practice-based research networks must adapt to fit the current climate.

Adding quality improvement activities that meet Maintenance of Certification Part 4 criteria to research study design adds value to a practice-based research protocol. This incentive meets the needs of busy physicians, and may help researchers meet study recruitment goals. (Read the full article)

The furore surrounding the arrival of over 200 Cuban medical doctors in South Africa to fight the coronavirus has highlighted a failure on the part of the SA government to explain the nature and drivers of our country’s relationship with Cuba, says Mills Soko.

Quiz Yourself: What are today's biggest challenges to teacher recruitment?

Denmark government along with the opposition party leaders have achieved political agreement to improve the nations international recruitment policy, which will facilitate the county’s enterprises to have easy access to highly qualified professionals…

VideoMyJob is helping transform recruitment. With support from the Landing Pads program, the startup has exceeded its global growth targets well beyond expectations.

A leading overseas talent recruitment platform in China is seeking to partner with Australian universities for its online internship system. Successful partners will work with established companies in China to provide online internship opportunities to graduates.

There are fundamental changes to the UK’s immigration rules in the pipeline. These will result in a new immigration system applying to non-British and Irish citizens and will not just therefore mean changes to the existing provisions in respect of y...

There are fundamental changes to the UK’s immigration rules in the pipeline. ...

Cellular starvation is typically a consequence of tissue injury that disrupts the local blood supply but can also occur where cell populations outgrow the local vasculature, as observed in solid tumors. Cells react to nutrient deprivation by adapting their metabolism, or, if starvation is prolonged, it can result in cell...

Cep57 has been characterized as a component of a pericentriolar complex containing Cep63 and Cep152. Interestingly, Cep63 and Cep152 self-assemble into a pericentriolar cylindrical architecture, and this event is critical for the orderly recruitment of Plk4, a key regulator of centriole duplication. However, the way in which Cep57 interacts with the Cep63-Cep152 complex and contributes to the structure and function of Cep63-Cep152 self-assembly remains unknown. We demonstrate that Cep57 interacts with Cep63 through N-terminal motifs and associates with Cep152 via Cep63. Three-dimensional structured illumination microscopy (3D-SIM) analyses suggested that the Cep57-Cep63-Cep152 complex is concentrically arranged around a centriole in a Cep57-in and Cep152-out manner. Cep57 mutant cells defective in Cep63 binding exhibited improper Cep63 and Cep152 localization and impaired Sas6 recruitment for procentriole assembly, proving the significance of the Cep57-Cep63 interaction. Intriguingly, Cep63 fused to a microtubule (MT)-binding domain of Cep57 functioned in concert with Cep152 to assemble around stabilized MTs in vitro. Thus, Cep57 plays a key role in architecting the Cep63-Cep152 assembly around centriolar MTs and promoting centriole biogenesis. This study may offer a platform to investigate how the organization and function of the pericentriolar architecture are altered by disease-associated mutations found in the Cep57-Cep63-Cep152 complex.

Dalton Buysse, Anna-Katharina Pfitzner, Matt West, Aurelien Roux, and Greg Odorizzi

The ESCRT-III protein complex executes reverse-topology membrane scission. The scission mechanism is unclear but is linked to remodeling of ESCRT-III complexes at the membrane surface. At endosomes, ESCRT-III mediates the budding of intralumenal vesicles (ILVs). In Saccharomyces cerevisiae, ESCRT-III activity at endosomes is regulated through an unknown mechanism by Doa4, an ubiquitin hydrolase that deubiquitylates transmembrane proteins sorted into ILVs. We report that the non-catalytic N-terminus of Doa4 binds Snf7, the predominant ESCRT-III subunit. Through this interaction, Doa4 overexpression alters Snf7 assembly status and inhibits ILV membrane scission. In vitro, the Doa4 N-terminus inhibits association of Snf7 with Vps2, which functions with Vps24 to arrest Snf7 polymerization and remodel Snf7 polymer structure. In vivo, Doa4 overexpression inhibits Snf7 interaction with Vps2 and also with the ATPase Vps4, which is recruited by Vps2 and Vps24 to remodel ESCRT-III complexes by catalyzing subunit turnover. Our data suggest a mechanism by which the deubiquitylation machinery regulates ILV biogenesis by interfering with ESCRT-III remodeling.

Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platelet-derived extracellular vesicles which rapidly and preferentially bound to blood monocytes compared to other leukocytes. Platelet-derived extracellular vesicle binding to monocytes was initiated by P-selectin-dependent adhesion and was stabilised by binding of phosphatidylserine. These interactions resulted in the progressive transfer of the platelet adhesion receptor GPIbα to monocytes. GPIbα^+-monocytes tethered and rolled on immobilised von Willebrand Factor or were recruited and activated on endothelial cells treated with TGF-β1 to induce the expression of von Willebrand Factor. In both models monocyte adhesion was ablated by a function-blocking antibody against GPIbα. Monocytes could also bind platelet-derived extracellular vesicle in mouse blood in vitro and in vivo. Intratracheal instillations of diesel nanoparticles, to model chronic pulmonary inflammation, induced accumulation of GPIbα on circulating monocytes. In intravital experiments, GPIbα⁺-monocytes adhered to the microcirculation of the TGF-β1-stimulated cremaster muscle, while in the ApoE^–/– model of atherosclerosis, GPIbα⁺-monocytes adhered to the carotid arteries. In trauma patients, monocytes bore platelet markers within 1 hour of injury, the levels of which correlated with severity of trauma and resulted in monocyte clearance from the circulation. Thus, we have defined a novel thrombo-inflammatory pathway in which platelet-derived extracellular vesicles transfer a platelet adhesion receptor to monocytes, allowing their recruitment in large and small blood vessels, and which is likely to be pathogenic.

Punjab Education Board Punjab Recruitment 2020 Online Application Last Date Extended at educationrecruitmentboard.com. Check details here.

Sarva Shiksha Abhiyan (SSA), Department of School Education Punjab, has published the recruitment notification for the post of Master/Mistress Cadre.

OSCB Recruitment 2020 Online Application for 786 is being filled up at rcsodisha.nic.in . Check details here.

RBI Recruitment 2020 Notification is out at rbi.org.in. Check details here.

The international Joint Center for Biomedical Innovation (JCBI) is comprised of two partner research nodes using nanoparticle technologies to develop solutions for cancer and neurodegenerative diseases diagnostics. Henan University has established a new research laboratory in nano-bio system innovation and theranostics, with start-up funding and new academic positions. Macquarie’s node is built upon its established excellence in neuroscience and cancer research programs. The collaborative succes…

Shandong First Medical University (Shandong Academy of Medical Sciences) has been actively promoting the strategy of “invigorating the university through talents” and therefore has formulated a series of high-level talent introduction programs, and welcome talents at home and abroad to join us.

1. Qualifications for Different Levels of Applicants:

(1) Strategic Talents

This level targets academicians or experts with the qualifications that the applicants should be no more than 65 …

About Peking University International Cancer Institute (PKUICI)
Peking University International Cancer Institute(PKUICI) was formally established in 2019. With the support of School of Basic Medical Sciences, Cancer Hospital, People's Hospital, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, School of Pharmaceutical Sciences, School of Public Health, College of Engineering and other affiliated hospitals of Peking University, PKUICI is aimed to attract and create wor…

Position
Laboratory director and independent principal investigators

Employer
Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine

Location
639 Zhi Zao Ju Rd, Huang Pu District, 200011, Shanghai, China

Discipline
Tissue engineering and regenerative medicine related disciplines including: Stem Cell, Developmental Biology, Biomaterials, Biomedical Engineering

Aim:
Shanghai Tissue Engineering Key Laboratory is among the l…

Join us for the 2015 St. Jude Walk Run to End Childhood Cancer! Hosted in 58 communities nationwide, St. Jude is leading the way the world understands, treats and defeats childhood cancer and other life threatening diseases.

Spurs’ former scout David Webb tells the story of how four supremely shrewd acquisitions helped take the team to the Champions League final

The anniversary falls on Friday. In the second extraordinary semi-final comeback in as many days, Tottenham overcame Ajax courtesy of a 96th-minute winner from their most recent recruit. A year and a half into his Spurs career, Lucas Moura completed his hat-trick. It was an advertisement for enforced continuity, an antidote to the obsession with spending as the only team in the top five European leagues to go through the season without signing anyone became Champions League finalists.

But it was not entirely true to call Tottenham the team without transfers. There was a golden age of recruitment under Mauricio Pochettino: not in 2018-19, but a seven-month spell in 2015 when Spurs brought in Dele Alli, Son Heung-min, Kieran Trippier and Toby Alderweireld all for less than £45m. Four years, and four top-four finishes later, each of a quartet which could have been valued at a combined £250m started the Champions League final.

Labour Minister, Shibu Baby John, said that the Kerala State government would make recruitment of trained nurses from the state completely free of cost.

Nothing drives the company like human resource do. With a talented, task-oriented human resource, a company is bound to get results. There is no dearth of talented professionals in India, particularly in the Delhi and national capital...

The aviation industry plays a major role in the growth and development of global economy. The Indian aviation sector is amongst the most promising ones, driven by a massive boom in tourism and increasing levels of disposable incomes. The...

As India's capital city and the most prosperous state with per capita income of Rs 2.01 lakhs in 2012-13, Delhi has become a nucleus of trade, commerce and industry in the northern region. The economy of Delhi has shown...

The Indian recruitment industry is driven by a number of factors including the growth of key industries, large conglomerates entering into new business domains, entry of multinational companies (MNCs) in the Indian markets among...

Bangalore, India’s start-up hub and its technology capital, is home to the Indian operations of many global corporations. The city is fast becoming an active business corridor dotted with office and retail spaces. Once seen as...

The Indian engineering sector is of strategic importance to the economy owing to its intense integration with other industry segments. The sector can be broadly categorised into two segments - heavy engineering and light...

Company: E-Hireo Global Solutions Private Limited
Experience: 0 to 2
location: Mumbai
Ref: 24823519
Summary: Recruit & train teachers at scale in delivering an excellent online classroom experience. Responsibilities and Duties

Company: Quotient Consultancy
Experience: 1 to 3
Salary: 3.00 to 5.00
location: Mumbai City
Ref: 24814012
Summary: Recruit & train teachers at scale in delivering an excellent online classroom experience

Company: P & I Management Consultants
Experience: 0 to 50
location: India, Ludhiana
Ref: 24729187
Summary: Job Description: Job Description  Recruitment/Resourcing: Responsible for managing the complete recruitment life cycle for sourcing the best talent of all levels from diverse sources after identification of....

Company: Seventh Contact Hiring Solutions
Experience: 0 to 5
location: Pune
Ref: 24511785
Summary: Women professionals who may have taken a career break for personal reasons and are now open to pursue a career in IT recruitment staying within Kharadi/Chandan Nagar/Viman Nagar area. This will be a Full-time role (9.30 AM to 5.30....

Company: MNR Solutions Private Limited
Experience: 0 to 50
location: India
Ref: 24341103
Summary: Job Description: Job description Hiring Freshers and experienced MBA/B.Tech candidates for recruitment executive role. work would be resume sourcing, interview schedule, Offer followup and MIS reporting. Salary:INR50,000 –....

Company: New Global Technologies
Experience: 0 to 5
location: Chennai, Mumbai
Ref: 24043123
Summary: Would be sourcing candidates from the given database, lining them up for an Interview, screening, briefing, putting them for Interview while co-ordinating with Hr's and handling inhouse drives. Salary negotiable+....

Critics of AI platforms doubt whether they eliminate human interviewers’ prejudices

Wearable tech will measure workers’ true productivity, supercharging capitalism

Pharma company’s use of algorithms marks fast-growing trend in big digitally-savvy markets including India

Like many other websites at the moment, the career-oriented networking platform LinkedIn has seen a big boost in traffic as a result of people being asked to work from home and stay indoors overall to slow the spread of the coronavirus, with a bump of 55% more conversational activity between existing connections in recent weeks. […]

The former Celtic and Aston Villa striker had been talking to Southend United about becoming part of their management team with Henrik Larsson and Johan Mjallby until Johnson pulled out.

Tommy Johnson has joined Blackpool's recruitment staff in a move which led to the collapse last week of Southend's bid to appoint Henrik Larsson as manager at Roots Hall.

Arsenal were warned against the signings of Shkodran Mustafi and Lucas Perez by their own head of recruitment in 2016, in the same window the club lost Serge Gnaby for just £5million.

The employment platform closed three offices on Monday, ordering more than 1,000 staff in Dublin, Sydney, and Singapore to work from home.