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Egyptian foreign minister visits Lebanon to push for ceasefire with Israel


Abdelatty met with a number of key officials in the country and reiterated his support for Lebanon and a ceasefire between Israel and Lebanon.




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PTA signals further VPN curbs

ISLAMABAD: Following a disruption that rendered virtual private networks (VPNs) dysfunctional across the country, the Pakistan Telecommunication Authority (PTA) on Wednesday said that VPN usage would be restricted in the future to curb access to pornographic content.

In a statement, the authority claimed it had so far blocked 100,183 URLs containing blasphemous content, as well as 844,008 pornographic websites.

The statement by PTA highlighting its performance came a day after the Ministry of Religious Affairs and Interfaith Harmony wrote to the regulator to ask it to block blasphemous and pornographic content.

“In addition to PTA’s proactive efforts, individuals and government organisations also report such sites,” the statement added.

The telecom regulator also claimed that approximately 20 million attempts were made from within the country to access pornographic websites on a daily basis, which were blocked at the international gateway level.

“However, users bypass restrictions via VPNs and access porn contents, PTA remains fully committed to curbing this issue, taking all necessary measures to block this content effectively,” the statement added.

In another statement, the telecom regulator said it had organised a consultation on the issue of VPN use, attended by representatives from the Ministry of IT & Telecommunication (MoIT&T), the Pakistan Software Export Board (PSEB), and the Pakistan Software Houses Association (P@SHA).

“The PTA introduced a stre­amlined VPN registration process, allowing legitimate users to register their VPNs through a new online portal at ipregistration.pta.gov.pk,” the statement said.

However, a senior executive from an internet service provider — in response to a Dawn query — said the authority was “making excuses”.

“How would they know that people are watching porn through VPNs? They have no capability to [monitor traffic through] VPNs, otherwise they would not block it,” the executive said.

He said the main target was blocking access to X and other social media platforms.

Published in Dawn, November 14th, 2024




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Matt Gaetz resigns from Congress 'effective immediately' following attorney-general nomination

House Speaker Mike Johnson announced that Rep. Matt Gaetz, who was tapped by President-elect Donald Trump to run the Justice Department, issued his resignation letter on Wednesday.




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Matt Gaetz resigns from Congress over Trump nod to be attorney general, Johnson says

Rep. Matt Gaetz is out of Congress, Speaker Johnson said, after he was tapped to be the next attorney general.



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  • Fox News
  • fox-news/politics/elections/presidential/trump-transition
  • fox-news/politics/executive/cabinet
  • fox-news/politics/house-of-representatives
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  • article

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Archbishop of Canterbury’s resignation ‘won’t fix the problem’, says Bishop of Dover on church abuse scandal

We spoke to the Bishop of Dover, Rose Hudson-Wilkin from Canterbury.




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Archbishop of Canterbury resigns after church abuse scandal

Justin Welby hasn’t said when he’ll go. But replacing him won’t be easy. Victims of decades of church abuse are calling for root and branch reform.




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Horoscope 14th November, 2024: Check astrological prediction for Virgo, Sagittarius and other signs - The Indian Express

  1. Horoscope 14th November, 2024: Check astrological prediction for Virgo, Sagittarius and other signs  The Indian Express
  2. Horoscope Today: November 14, 2024  VOGUE India
  3. Love and Relationship Horoscope for November 14, 2024  Hindustan Times
  4. Horoscope Today, November 14, 2024: Read your today's astrological predictions  The Times of India
  5. Aries Daily Horoscope Today (Mar 21 – April 19), November 14, 2024: Relationships will be comfortable!  India Today




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From high tariffs to isolation, what a 2nd Trump term might mean for foreign policy

With wars raging around the world and high tariffs looming, Economist editor-in-chief Zanny Minton Beddoes says Trump's agenda may be chaotic — but she remains optimistic about possible good elements.




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Bluesky surges to 15 million users after getting a million sign-ups in one week

Bluesky may still be the underdog in the race for alternatives to X, but the once Twitter-affiliated service is gaining momentum. The app just passed the 15 million user mark after adding more than a million new users over the last week, the company said in an update.

While Bluesky is still considerably smaller than Threads, which with 275 million users is its biggest rival, there are signs that Threads users have been increasingly curious about the upstart. “Bluesky” has been a trending topic on Threads in recent days and an in-app search suggestion shows there are more than 19,000 posts about “Bluesky.” Bluesky itself has also made a push to win over Threads users in recent weeks by posting regularly on the Meta-owned service.

That effort seems to be working. A month ago, Engadget noted, the service had just under 9 million users. Its mobile app also has the top spot in Apple’s App Store, followed by Threads and ChatGPT. Its recent success also seems to be driven, at least in part, by frustration with Elon Musk and X following the US presidential election.

A recent report from web analytics company SimilarWeb found that “more than 115,000 US web visitors deactivated their accounts,” on November 7, “more than on any previous day of Elon Musk’s tenure.” The report also noted that “web traffic and daily active users for Bluesky increased dramatically in the week before the election, and then again after election day,” with Bluesky at points seeing more web traffic than Threads. (Threads’ mobile usage, however, is still “far ahead” of Bluesky.)

SimilarWeb

“In the US, Bluesky got more web visits than Threads in the immediate aftermath of the election,” the report notes. “For context, it’s important to note that both services are app centric, even though they support a web user interface.”

On its part, Bluesky seems intent on distinguishing itself from its larger, billionaire-controlled rivals. The company, which began as an internal project at Twitter before it spun off into an independent entity, has experimented with novel features like custom feeds, user-created moderation services and “starter packs” for new users.

“You're probably used to being trapped in a single algorithm controlled by a small group of people, that's no longer the case,” Bluesky’s COO Rose Wang shared in a video aimed at new users Tuesday. “On Bluesky, there are about 50,000 different feeds … these feeds provide a cozy corner for you to meet people with similar interests. And you can actually make friends again, because you're no longer tied to a dominant algorithm that promotes either the most polarizing posts and or the biggest brands, and that's the mandate of Bluesky.”

This article originally appeared on Engadget at https://www.engadget.com/social-media/bluesky-surges-to-15-million-users-after-getting-a-million-sign-ups-in-one-week-224213573.html?src=rss




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Indonesian president says he will safeguard sovereignty in South China Sea

JAKARTA — Indonesian President Prabowo Subianto said he would "always safeguard our sovereignty" when asked about the issue of the South China Sea, adding partnerships are better than conflicts and that "we respect all powers". Prabowo's comments, made while he was in Washington on Wednesday (Nov 13), came after his foreign ministry stressed that Indonesia does not recognise China's claims over the South China Sea despite signing a maritime deal with Beijing last weekend. Beijing has long clashed with Southeast Asian nations over the South China Sea, which it claims almost in its entirety, based on a "nine-dash line" on its maps that cuts into the exclusive economic zones (EEZ) of several countries. "We respect all powers, but we will always safeguard our sovereignty. But I choose to always find possibilities of a partnership," said Prabowo, who has repeatedly said he will pursue a non-aligned foreign policy. "Partnerships are better than conflicts," he told reporters.




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'You didn't sign up to be a hotel': Free-spirit couple with 5 and 7-year-old kids sells their home to take "extended vacation," begs brother for help

If you suddenly showed up at your sibling's home and asked to live with them for 10 months, it would make things awkward, that's for certain. You can't just ask someone to live with them for that long without having a big discussion about what it would mean for you both. And this woman isn't just asking her brother to stay there alone… she wants to bring her entire family, including her two young children. 

While we always want to be there for the family members we adore, living with someone is a whole other ball game. This guy has his own home that he's spent a decade paying off. Now suddenly, his younger sister is begging to move in with him because of her own ill-fated adventures. She was living the dream: she sold her family's home in order to travel full-time. While many of us dream of doing things like that, there's a reason most people can't. It's just too expensive to maintain. The sister found this out within just two months of her perma-vacation… but should her brother really be expected to house his sister just because she intentionally chose to give up her house? Check out the full story below and see if you agree with commenters telling this guy to avoid housing her and possibly even cut her off. 

Up next, read about the drama that one stage mom started when she decided to divorce her long-distance husband over email, while also CC'ing his entire family, friend group, and workplace.





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Lignin-based Hydrogel: A Breakthrough in Wound Healing and Drug Delivery

Newly developed lignin-based hydrogel proves to be a promising tool for wound healing and controlled drug release, according to a new study. With the




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Lignin-based Hydrogel: A Breakthrough in Wound Healing and Drug Delivery

New lignin-based hydrogel represents a breakthrough in the fields of wound healing and drug delivery, offering innovative solutions for improved medical treatments.




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Accor Drives Asia Expansion with 27 New Hotel Signings in 2024

Accor, a global leader in hospitality, is accelerating the Group’s growth in Asia securing 27 hotel signings and 8,117 keys year-to-date. The expansion encompasses twelve brands throughout eight countries, from India to South Korea and Japan.




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Orient Express Corinthian Unveils Its Design and Interiors in All Their Splendour

The first of the two Orient Express yachts, will set sail in June 2026 to cruise the Mediterranean, Adriatic and Caribbean seas.




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Design Hotels Releases Further Forecast Trend Report, Seeing Demand for Community Drive the Future of Travel

Design Hotels, the community-driven portfolio of nearly 300 independent hotels, today announced its second annual Further Forecast trend report, which explores travelers’ growing desire to build deeper connections, and how this is shaping their expectations of experiences—and in turn, the future of travel.




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Saudi Foreign Minister Faisal bin Farhan Al Saud arrives in India, to meet EAM Jaishankar today

Saudi Arabia's Foreign Minister, Prince Faisal bin Farhan Al Saud, has arrived to hold talks with External Affairs Minister (EAM), S. Jaishankar.




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Laapataa Ladies renamed as Lost Ladies: Aamir Khan, Kiran Rao host special screening amid Oscars campaign in NY

On November 12, a new poster for the film was revealed, accompanied by a caption that read, "Official entry: India. Best International Feature Film - 97th Academy Awards."




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Did Kartik Aaryan ignore Tripti Dimri at Bhool Bhulaiyaa 3 success bash; netizens think so [Watch]

Speaking about the box-office clash, Bhushan Kumar said, "I am extremely happy for the love our film 'Bhool Bhulaiyaa 3' is receiving from the audience. It's been only a few days since the film hit the theatres and it has already done great business...Ya, I do feel the clash between (Bhool Bhulaiyaa 3 and Singham Again)"




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World Diabetes Day 2024: Top 5 Early Warning Signs of High Blood Sugar Levels That Appear In Morning - TheHealthSite

  1. World Diabetes Day 2024: Top 5 Early Warning Signs of High Blood Sugar Levels That Appear In Morning  TheHealthSite
  2. Tackling diabetes epidemic  The Hindu
  3. World Diabetes Day 2024: Why type 2 diabetes often goes unnoticed, early signs of this silent killer, and associated risks  The Economic Times
  4. World Diabetes Day 2024  PIB
  5. 86% diabetics in India facing anxiety, depression; women more affected: Report  Gujarat Samachar




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Indian Embassy in Kathmandu calls on diaspora to sign-up for Pravasi Bharatiya Divas Convention of January




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AP govt signs MoU worth Rs 65,000 cr with Reliance Industries for investment in CBG projects




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[LINK] A new design for Mark Boulton

Words to tattoo on your knuckles:

Over the past couple of years, my blog hasn’t felt my own, to a degree. It’s felt like I’ve been writ­ing for an audi­ence, post­ing stuff for oth­ers rather than myself. That’s arse-backwards. A blog should be about per­sonal expres­sion. The moment you start think­ing, and writ­ing, to please oth­ers then it’s a bind; it feels less like a per­sonal exer­cise and more of a job.

A beautiful, thoughtful redesign from Mark Boulton (and a responsive one at that). Go go, read read.




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Design of Interfacial Dual Schottky Junctions to Modulate Charge Transfer for Enhanced Piezo-assisted Photocatalytic Degradation RhB Performances

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00619D, Paper
Xiaoqi Jiang, Shengdong Sun, Yuqiao Wang, Lebing Zhao, Fangzhi Huang, Shikuo Li
Regulating charge transfer is a great challenge to improving the efficiency of piezoelectric photocatalytic reactions. Herein, sandwich-like Bi2WO6@Ag/MXene nanoflower spheres (BWO@Ag/MXene) with piezoelectric/plasma dual characteristics were synthesized by a facile...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bio-inspired design of a self-supported bismuth microforest for high performance sodium storage

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA00950A, Paper
Jia Bai, Yan Liu, Ben Pu, Qi Tang, Yongbin Wang, Ruihan Yuan, Jin Cui, Yi Yang, Xiaojia Zheng, Bin Zhou, Weiqing Yang
A self-supported bismuth microforest anode material, prepared by a simple, efficient and scalable in situ galvanic replacement approach, exhibits high performance for sodium-ion batteries.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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India among top 10 countries in patents, trademarks, and industrial designs: WIPO 2024 report




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Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06202G, Edge Article
Open Access
Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu Fang
Abstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Indonesia and Australia hold joint military drills after signing a new defense agreement

The Indonesian and Australian militaries are holding joint combat drills off Indonesia’s main island of Java with about 2,000 troops training in air, maritime, amphibious and land operations




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Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

RSC Med. Chem., 2024, 15,3778-3794
DOI: 10.1039/D4MD00281D, Research Article
Carolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. Pilli
A novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators

RSC Med. Chem., 2024, 15,3800-3816
DOI: 10.1039/D4MD00585F, Research Article
Marwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-Karmalawy
Novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3880-3888
DOI: 10.1039/D4MD00414K, Research Article
Phuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. Vo
Novel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling

RSC Med. Chem., 2024, 15,3746-3758
DOI: 10.1039/D4MD00122B, Research Article
Open Access
Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong Li
We designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors

RSC Med. Chem., 2024, 15,3862-3879
DOI: 10.1039/D4MD00313F, Research Article
Daniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro Accetta
This study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy

RSC Med. Chem., 2024, 15,3912-3912
DOI: 10.1039/D4MD90040E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
The content of this RSS Feed (c) The Royal Society of Chemistry




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Doctor stabbed at Kalaignar Centenary Super Speciality Hospital in Chennai; one arrested

The oncologist who was attacked has been identified as Balaji Jagannath. He has been admitted in the ICU, and his condition is said to be critical




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Pact for third ro-ro vessel of Kochi Corporation signed

The third vessel will serve as a standby for the two vessels that are owned by Kochi Corporation




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No roadmap yet for better traffic signage system in Kozhikode city

Emergency signboards and lane markings near roundabouts have not yet been introduced to streamline the traffic management




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This week's sponsor: O’REILLY DESIGN CONFERENCE

O’REILLY DESIGN CONFERENCE - get the skills and insights you need to design the products of the future. Save 20% with code ALIST




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Foreign banks diverge on RBI’s rate path as inflation hits 14-month high

Firm inflation and hawkish signals rule out December rate cuts, says DBS Bank; but slowing growth may sway RBI, notes Barclays Research 




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Equity markets slump as retail inflation soars, foreign fund outflows continue




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Supreme Court could have aligned AMU with aspirational India. It did not




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Photo-Scraping Business Ignores $39M Privacy Fine

A US company that used billions of online photos without permission for facial recognition faces a fine of more than $35 million. Regulators say they may hold directors of Clearview AI personally responsible after the company said the fine was unenforceable. Clearview has attracted the attention of regulators in several companies for the way it does business. It produces and licenses facial recognition software to law enforcement agencies, for example, to identify alleged offenders from crowd photos or live video. The software works thanks to a massive database of pictures which Clearview ... (view more)




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St. Ignatius of Antioch

Fr. Andrew Stephen Damick is the author of Bearing God: The Life and Works of St. Ignatius of Antioch He and Fr. Barnabas Powell discuss this Saint from the very early years of the Christian Church.




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Geopolitics, Foreign Policy, and the Orthodox Church

Father Barnabas Powell interviews John Sitilides, the Washington D.C.-based geopolitical strategist and professional corporate speaker, in a far-reaching conversation to explore and assess the complexities facing the Orthodox Church and its internal administrative challenges in addressing in the Russia-Ukraine conflict, the hierarchical tensions between the Ecumenical Patriarchate and the Moscow Patriarchate, Turkey's repression of Orthodox and other religious minorities, the Syria civil war, the Israeli-Palestinian divide, radical Islamism in the Balkans, the plight of Egypt’s Coptic community, and the stunning rise of Orthodox Ethiopia in the Horn of Africa.





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Foreigner blamed for Pattaya crash death

PATTAYA - A foreign woman has been arrested for crashing her car into a motorcycle, killing one person and injuring another.




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Geochemical database of Cretaceous High Arctic Large Igneous Province magmatic rocks, Arctic Canada

Bédard, J H; Saumur, B -M; Williamson, M -C; Tegner, C; Troll, V R; Deegan, F M; Evenchick, C A; Grasby, S E; Dewing, K. Geological Survey of Canada, Open File 8759, 2020, 7 pages, https://doi.org/10.4095/327829
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_327829.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_327829.jpg" title="Geological Survey of Canada, Open File 8759, 2020, 7 pages, https://doi.org/10.4095/327829" height="150" border="1" /></a>




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New constraints on the age, geochemistry, and environmental impact of High Arctic Large Igneous Province magmatism: tracing the extension of the Alpha Ridge onto Ellesmere Island, Canada

Naber, T V; Grasby, S E; Cuthbertson, J P; Rayner, N; Tegner, C. Geological Society of America Bulletin 2020 p. 1-17, https://doi.org/10.1130/B35792.1




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Element and isotopic signature of re-fertilized mantle peridotite as determined by nanopowder and olivine LA-ICPMS analyses

Lawley, C J M; Pearson, D G; Waterton, P; Zagorevski, A; Bédard, J H; Jackson, S E; Petts, D C; Kjarsgaard, B A; Zhang, S; Wright, D. Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg" title="Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464" height="150" border="1" /></a>