November 4 saw 3,000 shares trade on the Bermuda Stock Exchange, valued at $13,950.00 BD. 3,000 shares were traded by Argus Group Holdings Ltd, closing even at $4.65 per share. The BSX finished at 2,498.07, even on the day. There were 0 advances, 0 declines, and 52 remained unchanged. The full report for the day […]

November 5 saw 43,592 shares trade on the Bermuda Stock Exchange, valued at $519,557.00 BD. 9,892 shares were traded by Bank of N.T. Butterfield Ltd, closing even at $36.00 per share, while another 33,700 shares were traded by Argus Group Holdings Ltd, closing up 4.3% at $4.85 per share. The BSX finished at 2,502.84, up […]

November 6 saw 1,300 shares trade on the Bermuda Stock Exchange, valued at $ 6,045.00 BD. 1,300 shares were traded by Argus Group Holdings Ltd, closing down 4.1% at $4.65 per share. The BSX finished at 2,498.07, down 0.19% on the day. There were 0 advances, 1 decline, and 51 remained unchanged. The full report […]

November 7 saw 18,327 shares trade on the Bermuda Stock Exchange, valued at $414,535.50 BD. 10,327 shares were traded by Bank of N.T. Butterfield Ltd, closing up 1.4% at $36.50 per share, while another 8,000 shares were traded by Argus Group Holdings Ltd, closing up 1.1% at $4.70 per share. The BSX finished at 2,526.08, […]

November 8 saw 0 shares trade on the Bermuda Stock Exchange. The BSX finished at 2,526.08, even on the day. There were 0 advances, 0 decline, and 52 remained unchanged. The full report for the day is available here [PDF], and the full report for the week is available here [PDF]. Related Stories Bermuda Stock […]

Revolut, which claims to have over 45 million customers globally, launched Revolut X as its stand-alone exchange in the UK earlier this year.

Evaluation report for the inter-authority learning exchange between Shetland Islands, Falkirk and Glasgow Councils throughcare and aftercare teams. In February 2014 a member of the Throughcare and Aftercare team from Shetland, spent two weeks in each host authority as a means of developing and sharing practice, experience and learning. The report describes the planning process, in-situ experience, and post-exchange learning of participants, it also report highlights the positive learning outcomes and benefits achieved for all participating local authorities. The report identifies ideas for future applications of such a learning and practice exchange model to improve practice for looked after young people and care leavers.

JP Segrest
Feb 1, 1992; 33:141-166
Reviews

Identification of antibody-binding epitopes is crucial to understand immunological mechanisms. It is of particular interest for allergenic proteins with high cross-reactivity as observed in the lipid transfer protein (LTP) syndrome, which is characterized by severe allergic reactions. Art v 3, a pollen LTP from mugwort, is frequently involved in this cross-reactivity, but no antibody-binding epitopes have been determined so far. To reveal human IgE-binding regions of Art v 3, we produced three murine high-affinity mAbs, which showed 70–90% coverage of the allergenic epitopes from mugwort pollen–allergic patients. As reliable methods to determine structural epitopes with tightly interacting intact antibodies under native conditions are lacking, we developed a straightforward NMR approach termed hydrogen/deuterium exchange memory (HDXMEM). It relies on the slow exchange between the invisible antigen-mAb complex and the free 15N-labeled antigen whose 1H-15N correlations are detected. Due to a memory effect, changes of NH protection during antibody binding are measured. Differences in H/D exchange rates and analyses of mAb reactivity to homologous LTPs revealed three structural epitopes: two partially cross-reactive regions around α-helices 2 and 4 as well as a novel Art v 3–specific epitope at the C terminus. Protein variants with exchanged epitope residues confirmed the antibody-binding sites and revealed strongly reduced IgE reactivity. Using the novel HDXMEM for NMR epitope mapping allowed identification of the first structural epitopes of an allergenic pollen LTP. This knowledge enables improved cross-reactivity prediction for patients suffering from LTP allergy and facilitates design of therapeutics.

We developed a simple and rapid method to enrich protein N-terminal peptides, in which the protease TrypN is first employed to generate protein N-terminal peptides without Lys or Arg and internal peptides with two positive charges at their N-termini, and then the N-terminal peptides with or without N-acetylation are separated from the internal peptides by strong cation exchange chromatography according to a retention model based on the charge/orientation of peptides. This approach was applied to 20 μg of human HEK293T cell lysate proteins to profile the N-terminal proteome. On average, 1,550 acetylated and 200 unmodified protein N-terminal peptides were successfully identified in a single LC/MS/MS run with less than 3% contamination with internal peptides, even when we accepted only canonical protein N-termini registered in the Swiss-Prot database. Since this method involves only two steps, protein digestion and chromatographic separation, without the need for tedious chemical reactions, it should be useful for comprehensive profiling of protein N-termini, including proteoforms with neo-N-termini.

One Montana nonprofit tries to build connections between rural and urban students with exchange program.

Global exchange of information on compliance with national, regional, and international fisheries laws and regulations governing sustainable fishing is now possible with the launch of the Global [...]

From today Australian and Indonesian businesses and workers will have even greater opportunities to boost their skills and expertise, with the signing of an expanded Memorandum of Understanding on the Indonesia-Australia Skills Development Exchange Pilot.

Kim Seung-ho initiated the idea to host an exhibition featuring artworks by 30 Chinese and South Korean artists born in 1992, when China and the Republic of Korea established formal diplomatic relatio

… Seek targeted relief measures to save media, nation’s economy The Nigerian Guild of Editors (NGE), arising from the three-day All Nigeria Editors Conference (ANEC) in Yenagoa, the Bayelsa State Capital, has called on the federal government to urgently mitigate the negative impact of fuel subsidy removal and the exchange rate volatility on the economy. […]

The post Ease impact of fuel subsidy removal, exchange rate volatility, editors urge FG first appeared on Business Hallmark.

Research Innovation & Collaboration Exchange (RICE)

Duchess Sophie wins hearts after touching exchange at Windsor: WatchThe Duchess of Edinburgh, Sophie, accompanied a 21-year-old Emily, who has cerebral palsy, in a heartwarming gesture.Emily had taken part in the BBC Children in Need and The One Show's fundraiser, The Challenge Squad, in which she...

Opening remarks by Roberta Casali, ADB Vice-President for Finance and Risk Management, at the 2024 Asian Regional Forum on Investment Management of Foreign Exchange Reserves, 25 September 2024, Japan

Decision makers need to analyze, exchange, and disseminate statistical information effectively in today’s data-driven world. See how Statistical Data and Metadata eXchange (SDMX) standards are helping create robust data links across the globe.

A sovereign exposure exchange is a cost-effective risk management tool used by multilateral development banks (MDBs) to reduce sovereign portfolio concentration risks. It provides capital relief for MDBs by exchanging loan guarantees on credit exposure from borrowing countries where an MDB is highly concentrated for exposure to countries where the MBD’s exposure is lower or nonexistent.

The Pew Charitable Trusts sent comments Jan. 4 to the Office of the National Coordinator for Health Information Technology (ONC) and the Centers for Medicare & Medicaid Services (CMS) urging them to support the easy exchange of individuals’ health records through a pair of regulations.

Experts suggest that opening up organ exchange among unrelated individuals could expand the donor pool, potentially saving many lives. While this move

The J&K Legislative Assembly's recent resolution seeking the restoration of special status has ignited a fierce debate between the BJP and Congress.

Team TechCrunch wants you! Forget the village, people. It takes a battalion of smart, eager people to produce a world-class tech conference as epic as TechCrunch Disrupt. That’s where you come in. We’re looking for volunteers interested in work exchange. You give us 10 hours of your time, and we’ll give you a three-day pass […]

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1. The present revisional application has been preferred by the petitioner against an order dated 22.04.2022 passed by the learned Judge, 5th Special Court, Kolkata, in the proceeding being Special Case No. SEBI/39/2018.

2. The petitioner's case is that the petitioner had joined in Amrit Bio Energy and Industries Limited as an executive director on 27.04.2004, for the erection and commissioning of renewal energy power project. The said Amrit Bio Energy and Industries Limited is a group of companies under Amrit Projects Ltd. a company incorporated under the provisions of the companies Act, 1956. After being satisfied with the performance of the petitioner, Kailash Chand Dujari, the Managing Director of Amrit Projects Ltd. and its group of companies had offered the petitioner to become director of several other group companies of Amrit Projects Ltd. After joining the said Amrit Group the petitioner was to look into the development and set up of a power project of 10 M.W. in the District of Bankura, West Bengal. The said project was successfully completed under the supervision of the petitioner. The said Amrit Project Limited had started a business receiving deposits from the public at large without consulting with the petitioner. The petitioner had tendered resignation and resigned from the said Amrit Projects Limited and all its group of companies in the year 2013.

München ; Wien : De Gruyter Oldenbourg, [2023]

New York; Oxford : Berghahn Books, [2023]

National Bureau of Economic Research

National Bureau of Economic Research

National Bureau of Economic Research

National Bureau of Economic Research