bacteria

Biowaste valorization: multifunctional hybrid lignin/TiO2 nanostructures for bacterial-biocide disinfection and dye removal

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D4EN00091A, Paper
Open Access
Marica Gallo, Virginia Venezia, Marica Muscetta, Rossella Grappa, Mariavittoria Verrillo, Gianluca Landi, Raffaele Marotta, Giuseppina Luciani
Hybrid lignin TiO2 nanoparticles: red-ox activity enables biocide disinfection and dye removal.
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bacteria

Rapid Synthesis of MXenes and Its Potential Risk to Bacterial Communities in Tomato Rhizosphere

Environ. Sci.: Nano, 2024, Accepted Manuscript
DOI: 10.1039/D3EN00827D, Communication
cheng chen, Yuchen Liu, Houpu Zhang, Jie Ren, Chao Zhang, Mao Xu, Dan Liu, Yuru Wang, Weiwei Lei, Xiaoli Zhao
As a thriving group of two-dimensional (2D) nanomaterials, MXenes offer tremendous application and development prospects because of their excellent physical and chemical properties. Rhizosphere bacteria colonize the narrow ecosystem region...
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bacteria

MoS2-functionalized chitosan hydrogel with antibacterial and antioxidant functions promotes healing of infected diabetic wounds

Mater. Chem. Front., 2024, 8,3770-3789
DOI: 10.1039/D4QM00562G, Research Article
Yingjie He, Jiahe Guo, Hua Li, Jiaxi Jiang, Jing Chen, Guichun Yang, Xiaofan Yang, Zhenbing Chen, Cuifen Lu
Construction and application of a MoS2-based injectable self-healing composite hydrogel with antibacterial and antioxidant dual functions for promoting infected diabetic wound healing.
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bacteria

World’s smallest tape recorder built from bacteria

Mr. Wang and his team created the microscopic data recorder by taking advantage of CRISPR-Cas, an immune system in many species of bacteria.




bacteria

Effect of base methylation on binding and mobility of bacterial protein Hfq on double-stranded DNA

Lab Chip, 2024, 24,5137-5144
DOI: 10.1039/D4LC00628C, Paper
Jijo Easo George, Rajib Basak, Indresh Yadav, Chuan Jie Tan, Jeroen A. van Kan, Frank Wien, Véronique Arluison, Johan R. C. van der Maarel
Using nanofluidics to probe protein mobility on DNA reveals how DNA base methylation impacts protein–DNA interactions.
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bacteria

A novel multifunctional SERS microfluidic sensor based on ZnO/Ag nanoflower arrays for label-free ultrasensitive detection of bacteria

Anal. Methods, 2024, 16,2085-2092
DOI: 10.1039/D4AY00018H, Paper
Yue Liu, Guanwen Su, Wei Wang, Hongyuan Wei, Leping Dang
Design and working principle of bacterial capture and identification using a ZnO/Ag microfluidic SERS sensor array.
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bacteria

Human microbiome derived synthetic antimicrobial peptides with activity against Gram-negative, Gram-positive, and antibiotic resistant bacteria

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00383G, Research Article
Open Access
Walaa K. Mousa, Ashif Y. Shaikh, Rose Ghemrawi, Mohammed Aldulaimi, Aya Al Ali, Nour Sammani, Mostafa Khair, Mohamed I. Helal, Farah Al-Marzooq, Emilia Oueis
An AMP-derived short 15-mer peptide and its cyclic derivatives have low micromolar broad spectrum antibacterial activity, with rapid onset of bactericidal effect and a membrane-targeting mode of action.
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bacteria

Advances in antibacterial agents for Mycobacterium fortuitum

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00508B, Review Article
Carlos Roberto Tavolari Jortieke, Angélica Rocha Joaquim, Fernando Fumagalli
This review presents the recent findings on antibacterial agents against Mycobacterium fortuitum and reveals the most promising and effective chemical frameworks to inspire the development of new drugs.
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bacteria

Design, synthesis, and biological evaluation of pyrazole–ciprofloxacin hybrids as antibacterial and antibiofilm agents against Staphylococcus aureus

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00623B, Research Article
Ojaswitha Ommi, Priyanka Sudhir Dhopat, Shashikanta Sau, Madhu Rekha Estharla, Srinivas Nanduri, Nitin Pal Kalia, Venkata Madhavi Yaddanapudi
A series of pyrazole–ciprofloxacin hybrids were designed, synthesized, and tested for antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis, aiming to combat antibiotic resistance.
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bacteria

Novel quinoxaline-derived derivatives: design, synthesis, bioactive evaluation, SARs and preliminary antibacterial mechanism

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00670D, Research Article
Yuting Liu, Pengju Yang, Yunyun Zhou, Zhiwen Zhou
In the current study, we have designed and prepared a series of quinoxaline-based compounds, which were derived from o-phenylenediamine. Among which, compounds 5m-p displayed good to moderate antibacterial activity with...
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bacteria

Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00663A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Václav Pflégr, Klára Konečná, Jiřina Stolaříková, Jan Ősterreicher, Ondřej Janďourek, Martin Krátký
Linking pyridine-4-carbohydrazide to other antimicrobial agents via oxocarboxylic acids significantly enhances efficacy against mycobacteria with promising selectivity and safety profiles.
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bacteria

Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00626G, Research Article
Aleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan Veerappan
Lipidation modulates the Gram-selective antibacterial activity of QPyNATh.
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bacteria

Scientists found a bacteria tricked a wasp to get rid of its males

A new study reports Wolbachia may have taken it a bit too far, after scientists found it manipulated the evolution of Encarsia formosa wasps




bacteria

Strain rate controls alignment in growing bacterial monolayers

Soft Matter, 2024, 20,8468-8479
DOI: 10.1039/D4SM00625A, Paper
Blake Langeslay, Gabriel Juarez
A model of cell alignment in confined growing bacterial monolayers connecting net monolayer deformation to the behavior of individual cells.
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bacteria

A generalized model for predicting different morphologies of bacterial swarming on a porous solid surface

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01072H, Paper
Uttam Kumar, Pushpavanam Subramaniam
In this study, we develop a comprehensive two-phase model to analyze the dynamics of bacterial swarming on porous substrates. The two distinct phases under consideration are the cell and aqueous...
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bacteria

A Zr-based metal–organic framework drug release system with long-lasting antibacterial behavior for accelerating wound healing

Dalton Trans., 2024, Advance Article
DOI: 10.1039/D4DT02734E, Paper
Hui-Qian Zheng, Han-Xiao Feng, Bing-Xin Li, Yi-Fei Hui, Yi-Han Lin, Xian-Feng Su, Lai-Peng Yan, Zijie Zhou, Zu-Jin Lin, Faqiang Tang
A biocompatible Zr-based metal–organic framework drug release system, CIP@SU-102, was fabricated by the cation exchange method, which shows superior and long-lasting antibacterial activity as well as effective promotion of infected wound healing.
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bacteria

An acidity-triggered aggregation nanoplatform based on degradable mesoporous organosilica nanoparticles for precise drug delivery and phototherapy of focal bacterial infection

Dalton Trans., 2024, 53,17893-17901
DOI: 10.1039/D4DT02111H, Paper
Yunhan Huang, Wei Guo, Xinyu Wang, Jingrui Chang, Bo Lu
An acidity-triggered aggregation antibacterial nanoplatform based on biodegradable mesoporous organic silica nanoparticles, is reported. It enables precise drug release and spatial accuracy for photodynamic therapy and photothermal therapy.
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bacteria

Sustainable treatment for low ammonia nitrogen sewage wastewater in cold climates: natural polymer gel–organic synthetic polymer embedded anammox bacteria immobilized pellets

Environ. Sci.: Water Res. Technol., 2024, 10,2809-2830
DOI: 10.1039/D4EW00538D, Paper
Jun Li, Salma Tabassum, Hüseyin Altundag
Denitrification effect of the hybrid carrier-embedded anammox bacteria pellets to treat NH4+–N urban sewage wastewater at low temperature through batch and continuous tests.
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bacteria

Study reveals how 3D environments affect bacterial growth and survival

For over 300 years, scientists have primarily studied bacteria using liquid cultures or flat 2D plates in laboratory settings




bacteria

Team at Kolkata institute engineers bacteria to solve maths problems

In a groundbreaking experiment, Saha Institute scientists have built bacterial computers that behave like artificial neural networks




bacteria

Modulating the photodynamic modality of Au22 nanoclusters through surface conjugation of arginine for promoted healing of bacteria-infected wounds

Nanoscale, 2024, 16,20089-20099
DOI: 10.1039/D4NR03278K, Paper
Xinyue Dou, Sariah Saalah, Chel-Ken Chiam, Jianping Xie, Coswald Stephen Sipaut
An Au nanocluster (NC)-based photodynamic antibacterial is designed by conjugating arginine on the surface of Au22 NCs, achieving healing of bacteria-infected wounds via producing reactive oxygen species (ROS) and reactive nitrogen species (RNS).
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bacteria

Synthesis, Characterization, Genotoxicity Assessment and Antibacterial Applications of Zanthoxylum armatum Silver Nanoparticles (ZASNP) with Antibiotic Efficacy Enhancement Potential

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03608E, Paper
Open Access
Nikita Quadri, Manjunath M. Setty, Anshumali Awasthi, Usha Yogendra Nayak, Minakshi Singh, Sharad Sharma
The study aimed to develop alternative antibacterial treatments by combining traditional herbal knowledge with modern nanotechnology. This approach targets multiple bacterial strains, combats antibiotic resistance, and offers solutions for treating...
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bacteria

Trap & kill: a neutrophil-extracellular-trap mimic nanoparticle for anti-bacterial therapy

Biomater. Sci., 2024, 12,1841-1846
DOI: 10.1039/D4BM00145A, Paper
Jingtao Zheng, Lei Rong, Yao Lu, Jing Chen, Kai Hua, Yongzhong Du, Qiang Zhang, Weishuo Li
A neutrophil-extracellular-trap mimic nanoparticle effectively eliminates bacteria in a trap & kill manner.
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bacteria

N-Halaminated spermidine-containing polymeric coating enables titanium to achieve dual functions of antibacterial and osseointegration

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00061G, Paper
Hang Ren, Peng Wang, Hanwen Huang, Junshen Huang, Yuheng Lu, Yanfeng Wu, Zhongyu Xie, Youchen Tang, Zhaopeng Cai, Huiyong Shen
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
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bacteria

Multifunctional antibacterial hydrogels for chronic wound management

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00155A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu, Yuming Shen
Due to their distinctive physical and chemical properties as well as their biological functionalities, multifunctional antibacterial hydrogels possess significant advantages in the treatment of chronic wounds.
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bacteria

Recent progress in nanomaterials for bacteria-related tumor therapy

Biomater. Sci., 2024, 12,1965-1980
DOI: 10.1039/D3BM01952G, Review Article
Fuping Zhang, Shuyu Wang, Shuo Yang, Feihe Ma, Hui Gao
Recent progress in nanomaterials for bacteria-related tumor therapy in terms of chemotherapy, immunotherapy and synergistic therapy is summarized in this review in order to provide some insights into this emerging and rapidly growing research area.
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bacteria

A universal strategy to enhance photothermal conversion efficiency by regulating the molecular aggregation states for safe photothermal therapy of bacterial infections

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00412D, Paper
Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu
A universal strategy is developed to remarkably enhance the photothermal conversion efficiency of photothermal materials. This advancement enables effective treatment of drug-resistant bacterial infections through safe photothermal therapy.
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bacteria

pH-Responsive antibacterial metal–phenolic network coating on hernia meshes

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00289J, Paper
Rui Ding, Pandi Peng, Jingjing Huo, Kun Wang, Pengxiang Liu, Hanxue Wu, Likun Yan, Peng Li
This work demonstrates that CT coatings would be a promising material against implant-related infection in a pH-responsive manner including but not limited to the field of hernioplasty.
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bacteria

Bacteria make a meal of penicillin

Engineered bacteria could be used for bioremediation of antibiotic-contaminated soils




bacteria

Cortexyme raises $76 million to test bacterial protease inhibitor in Alzheimer’s




bacteria

Multilayer coating helps plastic dental devices stay clear of bacteria

A superhydrophilic film made of two sugar molecules could help prevent bacterial growth on the mouthpieces




bacteria

Multilayer coating could fight bacterial growth on plastic dental devices

Superhydrophilic film made of two sugar molecules could lead to cleaner retainers or tooth aligners




bacteria

Un patógeno recluta bacterias buenas en la piel para iniciar infecciones

Un estudio hace que los científicos se replanteen cómo se desarrollan las infecciones bacterianas




bacteria

Pathogen recruits good bacteria on skin to initiate infections

Study shakes up scientists’ understanding of how bacterial infections develop




bacteria

Membrane knocks out antibiotic-resistant bacteria

Combining UV disinfection with a photocatalytic membrane helps to reduce the bacteria and their genes in wastewater




bacteria

Membrane knocks out antibiotic-resistant bacteria

Combining UV disinfection with a photocatalytic membrane helps reduce the bacteria and their genes in wastewater




bacteria

Cholera bacteria infect more effectively with a simple twist of shape

Princeton University researchers have discovered that the bacteria behind the life-threatening disease cholera initiates infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate their victims' intestines. The researchers also identified the protein that allows Vibrio cholerae to morph, and found that it's activated through quorum sensing. The findings could lead to new treatments for cholera that target the bacteria's ability to change shape or penetrate the gut.




bacteria

Gut bacteria regulate nerve fibre insulation

Research suggests that gut bacteria may directly affect brain structure and function, offering new ways to treat multiple sclerosis and psychiatric conditions

Far from being silent partners that merely help to digest food, the bacteria in your gut may also be exerting subtle influences on your thoughts, moods, and behaviour. And according to a new study from researchers at University College Cork, your gut microbes might affect the structure and function of the brain in a more direct way, by regulating myelination, the process by which nerve fibres are insulated so that they can conduct impulses properly.

The surprising new findings, published today in the journal Translational Psychiatry, provide what is perhaps the strongest evidence yet that gut bacteria can have a direct physical effect on the brain, and suggest that it may one day be possible to treat debilitating demyelinating diseases such as multiple sclerosis, and even psychiatric disorders, by altering the composition of the gut’s microbial menagerie in some way or another.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: White matter might matter much more than we thought | Mo Costandi

Continue reading...




bacteria

Research reinforces the idea of embracing nonantibiotic approaches to treat bacterial infections

As interest in the application of plasma medicine -- the use of low-temperature plasma created by an electrical discharge to address medical problems -- continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry.




bacteria

'Havan' for bacteria-free homes: Study

Want to lead a healthy life and free your home from bacteria? Perform 'havan' at regular intervals.




bacteria

Plasma medicine research highlights its antibacterial effects, potential uses




bacteria

How extreme bacteria squeeze water from a stone

Cyanobacteria survive in one of the harshest environments on Earth by mining water from the rocks they live on




bacteria

Crystal structure, Hirshfeld surface analysis and inter­action energy, DFT and anti­bacterial activity studies of ethyl 2-[(2Z)-2-(2-chloro­benzyl­idene)-3-oxo-3,4-di­hydro-2H-1,4-benzo­thia­zin-4-yl]acetate

The title compound, C19H16ClNO3S, consists of chloro­phenyl methyl­idene and di­hydro­benzo­thia­zine units linked to an acetate moiety, where the thia­zine ring adopts a screw-boat conformation. In the crystal, two sets of weak C—HPh⋯ODbt (Ph = phenyl and Dbt = di­hydro­benzo­thia­zine) hydrogen bonds form layers of mol­ecules parallel to the bc plane. The layers stack along the a-axis direction with inter­calation of the ester chains. The crystal studied was a two component twin with a refined BASF of 0.34961 (5). The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions to the crystal packing are from H⋯H (37.5%), H⋯C/C⋯H (24.6%) and H⋯O/O⋯H (16.7%) inter­actions. Hydrogen-bonding and van der Waals inter­actions are the dominant inter­actions in the crystal packing. Computational chemistry indicates that in the crystal, C—HPh⋯ODbt hydrogen bond energies are 38.3 and 30.3 kJ mol−1. Density functional theory (DFT) optimized structures at the B3LYP/ 6–311 G(d,p) level are compared with the experimentally determined mol­ecular structure in the solid state. The HOMO–LUMO behaviour was elucidated to determine the energy gap. Moreover, the anti­bacterial activity of the title compound has been evaluated against gram-positive and gram-negative bacteria.




bacteria

Quantitative three-dimensional nondestructive imaging of whole anaerobic ammonium-oxidizing bacteria

Anaerobic ammonium-oxidizing (anammox) bacteria play a key role in the global nitrogen cycle and in nitrogenous wastewater treatment. The anammox bacteria ultrastructure is unique and distinctly different from that of other prokaryotic cells. The morphological structure of an organism is related to its function; however, research on the ultrastructure of intact anammox bacteria is lacking. In this study, in situ three-dimensional nondestructive ultrastructure imaging of a whole anammox cell was performed using synchrotron soft X-ray tomography (SXT) and the total variation-based simultaneous algebraic reconstruction technique (TV-SART). Statistical and quantitative analyses of the intact anammox bacteria were performed. High soft X-ray absorption composition inside anammoxosome was detected and verified to be relevant to iron-binding protein. On this basis, the shape adaptation of the anammox bacteria response to iron was explored.




bacteria

New bacteria genome may help solve mystery of how methylmercury is made

A new bacterial genome sequence could help researchers solve a mystery as to how microorganisms produce a highly toxic form of mercury.

The post New bacteria genome may help solve mystery of how methylmercury is made appeared first on Smithsonian Insider.




bacteria

Vultures remarkably tolerant to deadly bacteria, study reveals

A new study of microorganisms living on the skin and in the intestines of North America vultures (black and turkey vultures) has turned up a […]

The post Vultures remarkably tolerant to deadly bacteria, study reveals appeared first on Smithsonian Insider.




bacteria

Tiny ocean crustaceans wear invisibility cloak of living bacteria

Crustaceans that thrive in the vastness of the open ocean have no place to hide from their predators. Consequently, many creatures that live at depths […]

The post Tiny ocean crustaceans wear invisibility cloak of living bacteria appeared first on Smithsonian Insider.




bacteria

Study of bacteria inside guts of wild Canada geese shows greater danger than earlier studies exposed

In the early 20th century, Canada geese were considered endangered in the U.S. So in the 1950s and 1960s, birds from the Midwest were released […]

The post Study of bacteria inside guts of wild Canada geese shows greater danger than earlier studies exposed appeared first on Smithsonian Insider.




bacteria

Bacterial cell division at a glance

Christopher R. Mahone
Apr 8, 2020; 133:jcs237057-jcs237057
CELL SCIENCE AT A GLANCE




bacteria

Genetic redundancy aids competition among symbiotic bacteria in squid

Full Text:

The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments, say researchers at Penn State and the University of Wisconsin-Madison. Their new study provides insights into the molecular mechanisms of competition among bacteria. "Many organisms, including humans, acquire bacteria from their environment," said Tim Miyashiro, a biochemist and molecular biologist at Penn State and the leader of the research team. "These bacteria can contribute to functions within the host organism, like how our gut bacteria help us digest food. We're interested in the interactions among bacteria cells, and between bacteria and their hosts, to better understand these mutually beneficial symbiotic relationships." Cells of the bioluminescent bacteria Vibrio fisheri take up residence in the light organ of newly hatched bobtail squid. At night, the bacteria produce a blue glow that researchers believe obscures a squid's silhouette and helps protect it from predators. The light organ has pockets, or crypts, in the squid's skin that provide nutrients and a safe environment for the bacteria. "When the squid hatches, it doesn't yet have any bacteria in its light organ," said Miyashiro. "But bacteria in the environment quickly colonize the squid's light organ." Some of these different bacteria strains can coexist, but others can't. "Microbial symbioses are essentially universal in animals, and are crucial to the health and development of both partners," says Irwin Forseth, a program director in the National Science Foundation's Division of Integrative Organismal Systems, which funded the research. "The results from this study highlight the role small genetic changes can play in microbe interactions. Increased understanding will allow us to better predict organisms' performance in changing environments."

Image credit: Andrew Cecere