anip Vision correction method for tool center point of a robot manipulator By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A vision correction method for establishing the position of a tool center point (TCP) for a robot manipulator includes the steps of: defining a preset position of the TCP; defining a preset coordinate system TG with the preset position of the TCP as its origin; capturing a two-dimensional picture of the preset coordinate system TG to establish a visual coordinate system TV; calculating a scaling ratio λ of the vision coordinate system TV relative to the preset coordinate system TG; rotating the TCP relative to axes of the preset coordinate system TG; capturing pictures of the TCP prior to and after rotation; calculating the deviation ΔP between the preset position and actual position of the TCP; correcting the preset position and corresponding coordinate system TG using ΔP, and repeating the rotation through correction steps until ΔP is less than or equal to a maximum allowable deviation of the robot manipulator. Full Article
anip Control circuit and method for manipulating a power tool By www.freepatentsonline.com Published On :: Tue, 23 Sep 2014 08:00:00 EDT The present application discloses a control circuit for a power tool and a method for manipulating the power tool. The control circuit has a detection circuit for battery packs, a calculating control circuit, a battery capacity indicating circuit for indicating the calculation result of the battery capacity, and a current measure and calculating circuit for measuring the current flowing through motors. The calculation result further includes the voltages consumed by the battery pack internally and the discharge loop. The method for manipulating the power tool includes pressing the switch to electrically connect the motor and the battery pack, measuring the parameters of the battery pack and allowing the motor to operate or not according the measured parameters. Further, after the motor is in operation, the battery capacity is calculated and the results are displayed. Full Article
anip Manipulator and path generation method thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A manipulator and a method of generating the shortest path along which the manipulator moves to grip an object without collision with the object models a target object and a gripper into a spherical shape, measures a current position of the gripper and a position of the target object and a target position of the gripper, calculates an arc-shaped path in a two-dimensional plane along which the gripper needs to move by calculating an included angle of a triangle consisting of the position of the object and the current position and target position of the gripper, transforms the arc-shaped path in the two-dimensional plane into an arc-shaped path in a three-dimensional space using a transform matrix consisting of the position of the object and the current position and target position of the gripper, thereby automatically generating the shortest path of the manipulator. Full Article
anip Hand manipulated construction vehicle toy By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT This invention relates to hand manipulated toy construction equipment such as backhoes, trucks, etc. In one embodiment, the truck body is hollow at one end so that the truck may be manipulated by inserting one's arm into the truck body and grasping and manipulating a transverse dowel handle. Spring-loaded means are provided within the truck body and are coupled to the dumper to control the motion of the equipment. A sound module is also provided to simulate construction sounds. Full Article
anip Methods and systems for manipulating particles using a fluidized bed By www.freepatentsonline.com Published On :: Tue, 28 Jul 2015 08:00:00 EDT The present invention comprises methods and systems for manipulation of media and particles, whether inert materials or biomaterials, such as cells in suspension cell culture. The methods and systems comprise use of an apparatus comprising a rotating chamber wherein the actions of the combined forces fluid flow force and centrifugal force form a fluidized bed within the rotating chamber. Full Article
anip Suction gripper and manipulation system for ophthalmic lenses By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A suction gripper for transferring ophthalmic lenses from a storage cup into a centering cup has a suction head with several suction openings and several suction cups, wherein the suction cups are positioned on a convexly rounded surface. At least some of the suction openings are arranged in the suction cups and at least one suction opening is arranged remote from the suction cups on the suction head. The suction gripper is used in a manipulation system for ophthalmic lenses that encompasses ophthalmic lenses, a storage cup, a centering cup and the suction gripper. Full Article
anip Utensil manipulating article By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A utensil manipulating article has a sleeve formed of a pliable material. The sleeve is suitable for receiving the utensil therein. The sleeve is movable between a utensil-receiving position and a utensil-manipulating position. The sleeve has an adhesive material on an outer surface thereof. The adhesive is suitable for attaching to fingers of a user so as to allow the user to move the sleeve between the utensil-receiving position and the utensil-manipulating position. The adhesive material includes a first adhesive strip and second adhesive strip respectively placed on a first side and an opposite side of the sleeve. A liner is removably affixed over the first and second adhesive strips. Full Article
anip Livestock guide and manipulator By www.freepatentsonline.com Published On :: Tue, 05 Dec 1978 08:00:00 EST A livestock guide and manipulator panel prod is disclosed by this invention wherein electronic shocking circuitry is provided in combination with a hand-held livestock guiding and directing panel having electronic prods of said circuitry arranged on the surface of the panel. Full Article
anip Method and apparatus for manipulating single cells and small aggregates thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A well, in particular an open well (14) with an upper end having a vertical axis (101), for containing a liquid and particles contained within said liquid, characterized by comprising at least two manipulation electrodes (1, 2, 3, 31, 32, 36, 17, 40, 41) able to be powered by electrical voltages, in particular alternating electrical voltages, so as to manoeuvre particles within the well by means of the dielectrophoretic effect. A platform comprising a plurality of wells as described above and a method for using said well. Full Article
anip Page construction for improved manipulation and book incorporating the same By www.freepatentsonline.com Published On :: Tue, 17 Feb 2015 08:00:00 EST A book having a page construction for improved page manipulation. The book includes a plurality of pages bound together at an edge margin, wherein each page includes a bound edge and a plurality of free edges. At least one of the free edges of at least one of the pages includes an edge relief. The pages may comprise cardboard or other stiff material having a thickness. The free edges include opposed top and bottom edges and a side edge. The edge relief may extend along the entire side edge or only a portion thereof. The edge relief may be in the form of, for example, a chamfer, a bevel, a radius, a notch, a step, or the like. Full Article
anip Manipulator needle portion repairing method By www.freepatentsonline.com Published On :: Tue, 15 Apr 2008 08:00:00 EDT In a manipulator needle portion defect repairing method, the existence of an abrasion or a fracture in a needle portion for holding a sample at an end of a manipulator disposed in an FIB device is confirmed using a microscope function of the FIB device. The abrasion or the fracture in the needle portion is then repaired by chemical vapor deposition using a focused ion beam of the FIB device. Full Article
anip Micro manipulator for electrode movement in neural signal recording By www.freepatentsonline.com Published On :: Tue, 07 May 2013 08:00:00 EDT This disclosure relates to a micro manipulator having a simple structure and having high possibility of recording a biological signal of a neuron at a desired position by improving positioning resolution of an electrode disposed adjacent to a subject's brain neuron or an electrode holder attached with the electrode. The micro manipulator according to the disclosure includes: a motor which includes a shaft and a vibration portion; a mobile which is connected to the shaft so as to be movable along the shaft; and a frame which supports the motor, wherein an electrode is connected to the mobile in a direction parallel to a longitudinal direction of the shaft, and wherein when the mobile moves linearly in accordance with a vibration of the shaft due to the vibration portion, the electrode moves linearly. Full Article
anip Unique Vocal Production Bundle: Get 55% OFF VocalSynth 2, Manipulator & StereoSavage By rekkerd.org Published On :: Tue, 28 Apr 2020 10:03:55 +0000 Plugin Boutique has launched the exclusive Unique Vocal Production Bundle, a collection of three plugins for vocal processing at 55% off the regular price. You will often find vocals at the heart of modern music productions, and while achieving a professional vocal sound is paramount to creating a successful record, adding a touch of uniqueness […] The post Unique Vocal Production Bundle: Get 55% OFF VocalSynth 2, Manipulator & StereoSavage appeared first on rekkerd.org. Full Article Effect plugins News Sales and promotions iZotope Plugin Boutique Polyverse Music sale vocals
anip Toy maker Funskool inaugurates new factory in Ranipet By retail.economictimes.indiatimes.com Published On :: 2019-03-22T12:12:45+05:30 "The company will invest another Rs 15 crore in another three months. The factory is close to Chennai port, thereby facilitating easy exports to our buyers abroad. We are happy to inaugurate our third manufacturing facility in India and production has already begun ,” said John Baby, chief executive officer (CEO), Funskool. Full Article
anip California attorney general sues gas trading companies, alleging price manipulation By www.latimes.com Published On :: Mon, 4 May 2020 15:06:02 -0400 California on Monday sued two gasoline trading firms, alleging they took advantage of a 2015 refinery explosion in Torrance to improperly drive up the price at the pump. Full Article
anip Media and advertising: manipulating photos of people; going too far? By www.globalissues.org Published On :: Sun, 29 Jan 2012 23:09:00 GMT It has long been known that advertisers will “photoshop” (slang for editing photos to touch up or airbrush out imperfections) photos to make the subject more attractive. But many have pointed out that this subtle manipulation often goes too far. Young people, girls in particular, are bombarded with images of how they are supposed to look, contributing to many social and health problems as a result. The American National Advertising Division (the US advertising industry’s self-regulating watchdog) for example, recently moved to ban the misleading use of photoshopping and enhanced post-production in cosmetics adverts as it could be too misleading. In the UK some adverts have been banned because the effects of airbrushing has resulted in very misleading cosmetic adverts. France has even considered legislation to explicitly identify retouched images. Some will claim it is up to parents to teach their children how to recognize these things, but parents cannot often win against an army of professional psychologists, marketers and others all focused on pushing their own images onto children, when studies also say that children are not old enough tell the difference between commercial and other content. This page has been updated to add a section about this issue with further links, videos and examples. Read full article: Media and Advertising Full Article Mainstream Media
anip Use of cyclodextrins for manipulating cellular cholesterol content By feedproxy.google.com Published On :: 1997-11-01 AE ChristianNov 1, 1997; 38:2264-2272Articles Full Article
anip CBD News: Online platform allows policymakers and other partners to access global data layers, upload and manipulate their own datasets, and query multiple datasets to provide key information on the Aichi Biodiversity Targets and nature-based Sustainable By www.undp.org Published On :: Fri, 06 Jul 2018 00:00:00 GMT Full Article
anip [Anguttaranikaya pabbakanipata, phuk 11] By search.wellcomelibrary.org Published On :: Full Article
anip Elements of physical manipulation / by Edward C. Pickering. By feedproxy.google.com Published On :: London : Macmillan, 1874-1876. Full Article
anip Tibet: worshippers in a temple kneeling before statues of the Dalai Lama and the deity Manippe. Engraving by N. Parr, 17--, after J. Grueber. By feedproxy.google.com Published On :: [London?], [between 1700 and 1799?] Full Article
anip Head of exchange dealers arrested for dollar manipulation By www.dailystar.com.lb Published On :: 2020-05-08T14:21:00.0000000 Lebanese authorities detained the head of the exchange dealers syndicate Mahmoud Mrad in a bid to end the manipulation of the dollar in the parallel market, Financial Prosecutor Judge Ali Ibrahim said Friday. Full Article Local
anip News18 Urdu: Latest News Panipat By urdu.news18.com Published On :: visit News18 Urdu for latest news, breaking news, news headlines and updates from Panipat on politics, sports, entertainment, cricket, crime and more. Full Article
anip Scapy Packet Manipulation Tool 2.4.3rc2 By packetstormsecurity.com Published On :: Tue, 02 Jul 2019 14:10:41 GMT Scapy is a powerful interactive packet manipulation tool, packet generator, network scanner, network discovery tool, and packet sniffer. It provides classes to interactively create packets or sets of packets, manipulate them, send them over the wire, sniff other packets from the wire, match answers and replies, and more. Interaction is provided by the Python interpreter, so Python programming structures can be used (such as variables, loops, and functions). Report modules are possible and easy to make. It is intended to do the same things as ttlscan, nmap, hping, queso, p0f, xprobe, arping, arp-sk, arpspoof, firewalk, irpas, tethereal, tcpdump, etc. Full Article
anip Scapy Packet Manipulation Tool 2.4.3rc3 By packetstormsecurity.com Published On :: Fri, 12 Jul 2019 11:58:46 GMT Scapy is a powerful interactive packet manipulation tool, packet generator, network scanner, network discovery tool, and packet sniffer. It provides classes to interactively create packets or sets of packets, manipulate them, send them over the wire, sniff other packets from the wire, match answers and replies, and more. Interaction is provided by the Python interpreter, so Python programming structures can be used (such as variables, loops, and functions). Report modules are possible and easy to make. It is intended to do the same things as ttlscan, nmap, hping, queso, p0f, xprobe, arping, arp-sk, arpspoof, firewalk, irpas, tethereal, tcpdump, etc. Full Article
anip Scapy Packet Manipulation Tool 2.4.3rc4 By packetstormsecurity.com Published On :: Tue, 30 Jul 2019 18:30:52 GMT Scapy is a powerful interactive packet manipulation tool, packet generator, network scanner, network discovery tool, and packet sniffer. It provides classes to interactively create packets or sets of packets, manipulate them, send them over the wire, sniff other packets from the wire, match answers and replies, and more. Interaction is provided by the Python interpreter, so Python programming structures can be used (such as variables, loops, and functions). Report modules are possible and easy to make. It is intended to do the same things as ttlscan, nmap, hping, queso, p0f, xprobe, arping, arp-sk, arpspoof, firewalk, irpas, tethereal, tcpdump, etc. Full Article
anip Scapy Packet Manipulation Tool 2.4.3 By packetstormsecurity.com Published On :: Wed, 07 Aug 2019 20:38:28 GMT Scapy is a powerful interactive packet manipulation tool, packet generator, network scanner, network discovery tool, and packet sniffer. It provides classes to interactively create packets or sets of packets, manipulate them, send them over the wire, sniff other packets from the wire, match answers and replies, and more. Interaction is provided by the Python interpreter, so Python programming structures can be used (such as variables, loops, and functions). Report modules are possible and easy to make. It is intended to do the same things as ttlscan, nmap, hping, queso, p0f, xprobe, arping, arp-sk, arpspoof, firewalk, irpas, tethereal, tcpdump, etc. Full Article
anip AV Arcade Pro 5.4.3 Cookie Manipulation By packetstormsecurity.com Published On :: Sat, 15 Oct 2011 23:46:31 GMT AV Arcade Pro version 5.4.3 suffers from an insecure cookie vulnerability that allows for access bypass. Full Article
anip ANI Pharmaceuticals, Inc. (ANIP) CEO Arthur Przybyl on Q1 2020 Results - Earnings Call Transcript By seekingalpha.com Published On :: Sat, 09 May 2020 05:00:51 -0400 Full Article ANIP SA Transcripts
anip Can Believers Manipulate the Power and Presence of Christ? By feeds.gty.org Published On :: Mon, 15 Jul 2019 00:00:00 PST In the lead-up to the Truth Matters conference in October, we will be focusing our attention on the sufficiency, authority, and clarity of Scripture. Of our previous blog series, none better embodies that emphasis than Frequently Abused Verses. The following entry from that series originally appeared on October 2, 2015. -ed. Truly I say to you, whatever you bind on earth shall have been bound in heaven; and whatever you loose on earth shall have been loosed in heaven. Again I say to you, that if two of you agree on earth about anything that they may ask, it shall be done for them by My Father who is in heaven. For where two or three have gathered together in My name, I am there in their midst. (Matthew 18:18–20) How often have you heard that passage (or at least part of it) quoted in a church setting? During my time in the charismatic church, Matthew 18:18–20 was quoted in every prayer meeting and regularly from the pulpit. In fact, I cannot think of any other Scripture passage I heard quoted so frequently without ever hearing a sermon on the passage itself. And yet we would regularly bind demonic forces on earth and loose angelic armies from heaven. And we always reminded ourselves that Jesus was there because at least two or three of us were present. Our church was far from alone in its dependence on Matthew 18:18–20. In fact, the passage is a favorite of self-appointed experts in spiritual warfare and those who put special emphasis on Christ’s presence. The passage has been chopped up and subdivided all sorts of ways in service to a number of doctrinal positions and practical applications. For example, notorious faith healer and prosperity preacher Benny Hinn emphasizes Matthew 18:18 as a promise of supernatural power and heavenly authority: Do you realize that movements on earth govern movements in heaven? Do you realize that a child of God in prayer affects decisions in heaven? The Lord declared: “Whatsoever ye shall bind on earth shall be bound in heaven; and whatsoever ye shall loose on earth shall be loosed in heaven (Matthew 18:18). So awesome is this power that it releases angels to do God’s bidding on the earth and binds demons as it destroys the purpose of the enemy! [1]Benny Hinn, https://www.bennyhinn.org/tiyd-video/prayer-that-gets-results-part-1/ Contrast that with the conclusions of Rick Warren, who offers a far less spectacular interpretation and application of the passage, while employing similar hermeneutical technique in his assessment of verses 19–20: Many people miss out on so much because they only pray by themselves. Yet, when Jesus gave us an outline for prayer, he spoke about praying together. There is power in group prayer. If you’re not praying with other believers, then you’re not getting the support you need. You’re missing out on one of the major benefits of being a Christian. Jesus says “whenever two of you on earth agree about anything you pray for, it will be done for you by my Father in heaven. For where two or three come together in my name, I am there with them” (Matthew 18:19-20 TEV). That’s the power of praying with other people. [2]Rick Warren, http://rickwarren.org/devotional/english/a-powerful-key-to-prayer_700 Joyce Meyer comes out of the same Word Faith stream as Benny Hinn and also enjoys a huge television following. But her ministry prefers to traffic in practical advice for day-to-day life. She actually deploys Matthew 18:20 in the realm of marriage counsel: The Bible says that there is power in agreement. . . . If you want to have power in your marriage and in your prayer life, then you have to get along. The big question is: How can a disagreeing couple learn to agree? Agreement comes when the people involved stop being selfish. Selfishness is an immature inward focus. The key is to care about what the other person needs, be willing to humble yourself, and do what you can to meet those needs. When this happens, you can live together in agreement before the Lord, and “wherever two or three are gathered” in His name, God is there with them. So make a choice with your spouse today to pursue agreement and unity before the Lord. [3]Joyce Meyer, https://www.bible.com/reading-plans/199-promises-for-your-everyday-life/day/360 How can one passage support such disparate meanings? Are any of those interpretations the true meaning of Matthew 18:18–20? Do they skirt around the edges of the author’s original intent, or are they missing the point of the passage altogether? Bottom line: Does this passage have anything to do with spiritual warfare, group prayer, or marital unity? As with previous posts in this series, the first thing we should check is the context of our passage. What do the surrounding verses tell us about the meaning of our text? In this case, the preceding verses are likely just as familiar as the passage in question: If your brother sins, go and show him his fault in private; if he listens to you, you have won your brother. But if he does not listen to you, take one or two more with you, so that by the mouth of two or three witnesses every fact may be confirmed. If he refuses to listen to them, tell it to the church; and if he refuses to listen even to the church, let him be to you as a Gentile and a tax collector. (Matthew 18:15–17) Just a simple reading of the text makes it clear that the focus is not spiritual warfare, unity in marriage, or empowering your prayer meetings. Instead, verses 15–17 speak exclusively about church discipline. Therefore, all of Christ’s instructions about binding and loosing, unity, and the promise of His presence come in the context of church discipline. In other words, Matthew 18:18–20 means that when church leaders gather together to deal with unrepentant sinners, they have heavenly backing. In his commentary on this passage, John MacArthur explains how many of the popular interpretations go wrong when they divorce the verses from their context: Jesus’ promises in verses 18 and 19 have suffered serious misinterpretation throughout the history of the church. . . . Many charismatics use these promises—along with others, such as those of Matthew 7:7 and 21:22—to claim from God every imaginable blessing and privilege just for the asking. But in light of the context of what Jesus had just said, in the light of common rabbinical expressions of that day, and in light of the grammatical construction of the text, it is clear that He was not teaching that God’s power can be bent to men’s will. He was not saying that men can force heaven to do things. Quite to the contrary, His promise was that when His people bend their wills to His, He will endorse and empower their act of obedience. Jesus was here continuing His instruction about church discipline. He was not speaking about petitioning God for special blessings or privileges, and even less was He teaching that the church or any of its leaders has power to absolve the sins of its members. He was declaring that the church has a divine mandate to discipline its members when they refuse to repent. [4]John MacArthur, The MacArthur New Testament Commentary: Matthew 16–23 (Chicago: Moody Publishers, 1988) 137. And what about the power to bind and loose in the spiritual realm? John also carefully debunks that misinterpretation: The rabbis sometimes spoke of a principle or action as being bound in heaven or loosed in heaven to indicate, respectively, that it was forbidden or permitted in light of God’s revealed Word. . . . Believers have authority to declare that sins are either forgiven or not forgiven when that declaration is based on the teaching of God’s Word. If a person has received Jesus Christ as Savior and Lord, the church can tell him with perfect confidence that his sins are loosed, that is, forgiven, because he has met God’s condition for forgiveness, namely, trust in His Son. If, on the other hand, a person refuses to receive Christ as Savior and acknowledge Him as Lord, the church can tell him with equal confidence that his sins are bound, that is, not forgiven, because he has not met God’s condition for forgiveness. [5] The MacArthur New Testament Commentary: Matthew 16–23, 137. Matthew 18:15–17 is Christ’s explanation of how church discipline is to be practiced. Verses 18–20 expand on His instructions by informing us of the immense heavenly support provided to leaders who maintain the discipline of the church. Here’s how John MacArthur describes it: Jesus also assures His people that He Himself acts with them when they work to purify the church: “For where two or three have gathered together in My name, there I am in their midst.” Not only does the Father confirm discipline when it is administered according to His Word, but the Son adds His own divine confirmation. . . . To use this statement to claim the Lord’s presence at a small worship service or prayer meeting does not fit the context of church discipline and is superfluous. Christ is always present with His people, even with a lone believer totally separated from fellow Christians by prison walls or by hundreds of miles. The context demands that the two or three are witnesses in the process of discipline. To ask or to do anything in God’s name is not to utter His name but to ask and to work according to His divine will and character. For the witnesses to have gathered in His name is therefore for them to have faithfully performed their work of verifying the repentance or impenitence of a sinning brother or sister on the Lord’s behalf. When the church gathers in the Lord’s name and for His cause and glory, it must be engaged in self-purifying ministry under His power and authority, and with His heavenly confirmation and partnership. [6] The MacArthur New Testament Commentary: Matthew 16–23, 138. One could make a case that the church’s silence on the issue of biblical discipline (Matthew 18:15-17) has allowed for a cacophony of misinterpretations and misapplications of Matthew 18:18-20. Ripped from their original setting and intent, those verses have been made to serve a variety of false positions and pretexts. Our interpretation of Scripture has serious practical repercussions. We would all do well to receive Paul’s counsel to Timothy: “Be diligent to present yourself approved to God as a workman who does not need to be ashamed, accurately handling the word of truth” (2 Timothy 2:15). Full Article
anip Ayushmann Khurrana recalls manipulative offers made by directors during his initial days By feedproxy.google.com Published On :: Tue, 05 May 2020 10:33:00 +0500 Ayushmann Khurrana is riding high in his career right now but the road to success was no bed of roses for him Full Article
anip How to make noodles: the art and science of manipulating gluten By www.newscientist.com Published On :: Wed, 18 Mar 2020 18:00:00 +0000 It's easy and fun to make hand-pulled noodles, especially if you understand how gluten is acting inside the dough to make it stretch y and elastic, says Sam Wong Full Article
anip Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection By mbio.asm.org Published On :: 2020-03-17T01:30:14-07:00 ABSTRACT Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic studies that show an association of secretor status with infection caused by several genotypes. The fucosyltransferase 2 gene (FUT2) affects HBGA expression in intestinal epithelial cells; secretors express a functional FUT2 enzyme, while nonsecretors lack this enzyme and are highly resistant to infection and gastroenteritis caused by many HuNoV strains. These epidemiologic associations are confirmed by infections in stem cell-derived human intestinal enteroid (HIE) cultures. GII.4 HuNoV does not replicate in HIE cultures derived from nonsecretor individuals, while HIEs from secretors are permissive to infection. However, whether FUT2 expression alone is critical for infection remains unproven, since routinely used secretor-positive transformed cell lines are resistant to HuNoV replication. To evaluate the role of FUT2 in HuNoV replication, we used CRISPR or overexpression to genetically manipulate FUT2 gene function to produce isogenic HIE lines with or without FUT2 expression. We show that FUT2 expression alone affects both HuNoV binding to the HIE cell surface and susceptibility to HuNoV infection. These findings indicate that initial binding to a molecule(s) glycosylated by FUT2 is critical for HuNoV infection and that the HuNoV receptor is present in nonsecretor HIEs. In addition to HuNoV studies, these isogenic HIE lines will be useful tools to study other enteric microbes where infection and/or disease outcome is associated with secretor status. IMPORTANCE Several studies have demonstrated that secretor status is associated with susceptibility to human norovirus (HuNoV) infection; however, previous reports found that FUT2 expression is not sufficient to allow infection with HuNoV in a variety of continuous laboratory cell lines. Which cellular factor(s) regulates susceptibility to HuNoV infection remains unknown. We used genetic manipulation of HIE cultures to show that secretor status determined by FUT2 gene expression is necessary and sufficient to support HuNoV replication based on analyses of isogenic lines that lack or express FUT2. Fucosylation of HBGAs is critical for initial binding and for modification of another putative receptor(s) in HIEs needed for virus uptake or uncoating and necessary for successful infection by GI.1 and several GII HuNoV strains. Full Article
anip Limits to sustained energy intake. XXX. Constraint or restraint? Manipulations of food supply show peak food intake in lactation is constrained [RESEARCH ARTICLE] By jeb.biologists.org Published On :: 2020-04-16T04:02:51-07:00 Zhi-Jun Zhao, Davina Derous, Abby Gerrard, Jing Wen, Xue Liu, Song Tan, Catherine Hambly, and John R. Speakman Lactating mice increase food intake 4- to 5-fold, reaching an asymptote in late lactation. A key question is whether this asymptote reflects a physiological constraint, or a maternal investment strategy (a ‘restraint’). We exposed lactating mice to periods of food restriction, hypothesizing that if the limit reflected restraint, they would compensate by breaching the asymptote when refeeding. In contrast, if it was a constraint, they would by definition be unable to increase their intake on refeeding days. Using isotope methods, we found that during food restriction, the females shut down milk production, impacting offspring growth. During refeeding, food intake and milk production rose again, but not significantly above unrestricted controls. These data provide strong evidence that asymptotic intake in lactation reflects a physiological/physical constraint, rather than restraint. Because hypothalamic neuropeptide Y (Npy) was upregulated under both states of restriction, this suggests the constraint is not imposed by limits in the capacity to upregulate hunger signalling (the saturated neural capacity hypothesis). Understanding the genetic basis of the constraint will be a key future goal and will provide us additional information on the nature of the constraining factors on reproductive output, and their potential links to life history strategies. Full Article
anip Video Friday: Transferring Human Motion to a Mobile Robot Manipulator By feedproxy.google.com Published On :: Fri, 18 Oct 2019 21:05:00 GMT Your weekly selection of awesome robot videos Full Article robotics robotics/robotics-hardware
anip Facebook posts from 2012 show early Iranian attempts to manipulate U.S. politics By www.nbcnews.com Published On :: Thu, 07 May 2020 20:10:00 GMT The attempts seem to be experiments that were quickly abandoned, and none of those identified received substantial engagement. Full Article
anip Lenny Henry's daughter posed as comedian and sent 'manipulative' false messages in attempt to win back boyfriend By www.independent.co.uk Published On :: 2020-05-07T09:07:00Z Billie Henry was given a five-year restraining order Full Article
anip Twitter is suspending 70 pro-Bloomberg accounts, citing 'platform manipulation' By www.latimes.com Published On :: Sat, 22 Feb 2020 00:40:09 -0500 Twitter said it would suspend 70 accounts posting content supporting the Michael Bloomberg campaign in a pattern that violates company rules. Full Article
anip How to manipulate light on the nanoscale over wide frequency ranges By www.eurekalert.org Published On :: Fri, 08 May 2020 00:00:00 EDT An international team has discovered an effective method for controlling the frequency of confined light at the nanoscale in the form of phonon polaritons (light coupled to vibrations in the crystal). The results have now been published in Nature Materials. Full Article
anip Former AIG Vice President Sentenced to Four Years in Prison for Role in Fraudulent Manipulation Scheme By www.justice.gov Published On :: Tue, 27 Jan 2009 17:01:37 EST The former vice president of reinsurance of American International Group Inc. (AIG), was sentenced today to four years in prison for his role in a fraudulent scheme to manipulate AIGs financial statements. Full Article OPA Press Releases
anip Five Individuals Indicted for Devising and Participating in Stock Manipulation Scheme By www.justice.gov Published On :: Tue, 10 Feb 2009 20:10:34 EST A 24-count indictment charging five individuals with various crimes arising from an alleged scheme to defraud investors through the manipulation of the publicly traded stocks of three companies was unsealed today in Tulsa, Okla. Full Article OPA Press Releases
anip Attorney Indicted for Conspiracy and Wire Fraud in Stock Registration and Manipulation Scheme By www.justice.gov Published On :: Fri, 13 Mar 2009 16:16:37 EDT A securities attorney was charged in an indictment unsealed today with participating in a stock registration evasion scheme involving nine different publicly traded companies and with defrauding investors in a manipulation scheme related to three of the companies. Full Article OPA Press Releases
anip South Florida Stock Trader Pleads Guilty to Market Manipulation Scheme By www.justice.gov Published On :: Tue, 17 Mar 2009 16:50:27 EDT A stock trader from Jupiter, Fla., pleaded guilty today to engaging in a market manipulation scheme involving several publicly traded companies. Earlier today, Paul M. Gozzo, 33, pleaded guilty before U.S. District Judge Donald L. Graham in Miami to one count of conspiracy to commit securities fraud and one count of securities fraud. Full Article OPA Press Releases
anip Senior Executives of Auto Parts Retailer Charged with Scheme to Manipulate Corporate Earnings By www.justice.gov Published On :: Wed, 8 Apr 2009 15:59:07 EDT Two former senior executives of CSK Auto Corp. (CSK), have been charged in a 31-count indictment for a scheme to manipulate the companys reported earnings. The indictment, returned on April 7, 2009, by a federal grand jury in Phoenix, charges Martin G. Fraser, 53, of Glendale, Ariz., and Don W. Watson, 53, of Gilbert, Ariz., with conspiracy, securities fraud, mail fraud, false filings with the U.S. Securities and Exchange Commission (SEC), false books and records, and false statements to its auditor. Full Article OPA Press Releases
anip Texas Attorney Convicted for Role in Pump-and-dump Stock Manipulation Schemes By www.justice.gov Published On :: Thu, 28 Jan 2010 17:26:19 EST Phillip Windom Offill Jr., 51, of Dallas, was indicted on March 12, 2009, and today was found guilty of one count of conspiracy to commit registration violations, securities fraud and nine counts of wire fraud. Full Article OPA Press Releases
anip Kentucky Attorney Pleads Guilty for Role in Stock Manipulation Scheme and Obstruction of Justice By www.justice.gov Published On :: Fri, 26 Mar 2010 17:07:51 EDT Louisville, Ky., attorney James Reskin, 51, pleaded guilty late yesterday in U.S. District Court in Tulsa for his role in a scheme to defraud investors through the manipulation of the publicly traded stocks of three companies. Full Article OPA Press Releases
anip Two Oklahoma Men Convicted of Devising and Participating in Stock Manipulation Scheme By www.justice.gov Published On :: Tue, 4 May 2010 11:05:30 EDT G. David Gordon, a Tulsa, Okla., attorney, and Richard Clark, also of Tulsa, were convicted today by a federal jury of devising and participating in a scheme to defraud investors through the manipulation of publicly traded stocks of three companies. Full Article OPA Press Releases
anip Securities Attorney and Former Stock Broker Each Sentenced to More Than 12 Years in Prison for $43 Million Pump-and-Dump Stock Manipulation Scheme By www.justice.gov Published On :: Fri, 29 Oct 2010 16:10:18 EDT A securities attorney and a former stock broker were sentenced today to 188 months and 151 months in prison, respectively, for their roles in an extensive pump-and-dump stock manipulation scheme. Full Article OPA Press Releases
anip Securities Attorney and Five Others Indicted for Conspiracy, Wire and Mail Fraud in Stock Manipulation Scheme By www.justice.gov Published On :: Fri, 18 Feb 2011 14:13:19 EST Six individuals, including a securities attorney, were charged in an indictment unsealed today with defrauding investors in a stock manipulation scheme from 2003 to 2008. Full Article OPA Press Releases
anip Stock Promoters Indicted for Conspiracy in Stock Manipulation Scheme By www.justice.gov Published On :: Mon, 2 May 2011 18:57:17 EDT Three stock promoters have been indicted for their roles in a stock manipulation scheme that defrauded investors. Full Article OPA Press Releases