administration

Trump builds hawkish team with Rubio and Waltz tipped for top jobs | Trump administration | The Guardian




administration

Exclusive — Speaker Johnson Orders Entire Biden Administration to Preserve and Retain All Records and Documents

House Speaker Mike Johnson on Tuesday ordered the entire administration of President Joe Biden to preserve all records and communications in the waning days of the outgoing Democrat administration as former President Donald Trump’s team prepares to take over.

The post Exclusive — Speaker Johnson Orders Entire Biden Administration to Preserve and Retain All Records and Documents appeared first on Breitbart.




administration

The Trump Administration Will Shake Up Options Markets. How to Profit




administration

Media executives say that some brands were preparing to advertise on X once again, as Elon Musk was likely to gain an influential Trump administration role




administration

Trump Picks Gov Puppy Killer For Key Role In His Administration

Prissydent-elect Donald Trump has picked South Dakota Governor Kristi Noem, who penned the book 'No Going Back' that detailed her murdering a puppy, horses, and at least one goat, as his next secretary of the Department of Homeland Security.

Hey, at least he didn't pick Ted Nugent, Kid Rock, Marjorie Taylor Greene, Lauren Boebert, Catturd, or Steve Bannon for the role, all of whom allegedly have not shot a dog in the face -- yet.

CNN reports:

Noem will be tapped to take over the agency as two key immigration hardliners — Stephen Miller and Tom Homan — are slated to serve in senior roles, signaling Trump is serious about his promise to crack down on his immigration pledges. With his selection of Noem, Trump is ensuring a loyalist will head an agency he prioritizes and that is key to his domestic agenda.

The department saw an immense amount of turmoil the last time Trump was in office. Then, DHS had five different leaders, only two of whom were Senate-confirmed. The agency has a $60 billion budget and hundreds of thousands of employees.

Noem, who previously was a South Dakota representative, will now be tasked with overseeing a sprawling agency that oversees everything from US Customs and Border Protection and Immigration and Customs Enforcement to the Federal Emergency Management Agency and the US Secret Service.

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administration

20 years of The Practice of System and Network Administration!

Twenty years ago the first edition of The Practice of System and Network Administration shipped! Since then there has been a 2nd and 3rd edition (2006 and 2014), plus a sequel book The Practice of Cloud System Administration, and many printings. (see the timeline here)

When we started the project we had no idea if it would be a success. There was a real chance it could be a flop. Many people told us that our proposal was illogical: How could you have a book about system administration that is vendor agnostic and talks about process and people instead of specific tools and operating systems? Well, to be honest, we took a deep breath and started writing anyway. It took 2+ years but in Sept/Oct 2001 the book finally shipped!

Instead of a flop, the reaction we got was very positive! It has sold tens of thousands of copies. Many universities have used the book and its future editions as text books. It received the Usenix LISA Outstanding Achievement Award. One DevOps pundit told me she considers it to be "the first devops book" which was quite humbling.

When I visited Google in 2004 (a year before I considered joining) I was told everyone in the "systems operations" team was given a copy on their first day. The person giving me a tour then took me to a supply closet with 30 copies awaiting to be distributed to new hires.

However the real satisfaction comes from how it has helped others. Fans have related many heartwarming stories. Many fans have told us they felt like reading the book was a turning point in their life, that the book "turned me into a professional system administrator".

To thank our readers, our publisher is offering a special deal: 45% off the latest editions now until Oct 31, 2021 What? You still have the 2nd edition and haven't seen the dozens of chapters of new material in the 3rd edition? Or maybe you haven't heard of our Cloud book? Now is your chance to get the 3rd edition or the cloud sequel!

Thank you to everyone that gave us feedback on the early drafts! Thank you to all our readers! This book changed our lives and we hope it changed yours too!

P.S. We would love to hear from you! Please post a comment with reflections on the book.




administration

Meet the new Trump administration staffers who will shape key US policies

Trump has started filling key White House roles, starting with Susie Wiles as his chief of staff.




administration

It's official: Trump hands Musk efficiency role in new administration

Elon Musk and Vivek Ramaswamy will lead the Department of Government Efficiency, also known as DOGE, under Donald Trump's administration, Trump said.




administration

Breaking: Musk, Ramaswamy Officially Join Trump Administration - Their Job Is to Destroy Bureaucracy

Pro-Trump businessmen Elon Musk (the richest man in the world) and Vivek Ramaswamy have officially joined the incoming Trump administration. President-elect Donald Trump announced in a statement published Tuesday that […]

The post Breaking: Musk, Ramaswamy Officially Join Trump Administration - Their Job Is to Destroy Bureaucracy appeared first on The Western Journal.




administration

House Administration - 12/9/2024

Time: 9:00 AM, Location: E2.010




administration

Intraarterial Administration of Peptide Receptor Radionuclide Therapy in Patients with Advanced Meningioma: Initial Safety and Efficacy

Visual Abstract




administration

Feasibility of 177Lu-PSMA Administration as Outpatient Procedure for Prostate Cancer




administration

Education Programs Would Be Spared Under Trump Administration's Green Card Proposal

While the Trump administration proposal would not strip student eligibility for Head Start, the federal school lunch program, or the Individual with Disabilities Education Act, it could still affect millions of school-aged children who live with immigrant parents.




administration

WATCH: Harris cheered on by administration staff as she arrives at the White House

Vice President Kamala Harris received a grand welcome to the White House on Tuesday afternoon — cheered on by hundreds of administration staff as her SUV pulled up to the West Wing.




administration

Iran Open To Talks With Trump Administration If Interests Align

Iran will pursue whatever secures its interest, government spokesperson Fatemeh Mohajerani said on Tuesday, when asked if there could be direct talks with the Trump administration.




administration

Attorney General Jennings Fights Trump Administration’s Attempts to Reduce Census Efforts

Suit comes at a time when Delaware response rates are lagging. Attorney General Kathy Jennings has joined a large coalition of attorneys general, cities, counties, and the bipartisan U.S. Conference of Mayors in taking legal action against the Trump Administration’s impairment of the 2020 Decennial Census. The coalition filed an amicus brief in National Urban League v. […]



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administration

Carney Administration Prioritizes Farmland Preservation, Preserving Highest Number of Farms

The Delaware Department of Agriculture announced the 28th round of easement selections by the Delaware Agricultural Lands Preservation, preserving 40 farms and 2,262 acres of farmland. With this announcement, the Carney administration has preserved 403 farms, the highest number in the program’s history.




administration

Carney Administration Outlines Investments in Electric Vehicle Infrastructure

DOVER, Del. – Governor Carney joined Lieutenant Governor Bethany Hall-Long, Department of Transportation Secretary Nicole Majeski, Department of Natural Resources and Environmental Control Secretary Shawn Garvin, elected officials and advocates on Friday afternoon to outline investments in the state’s electric vehicle infrastructure. With a combination of state and federal funding, charging stations for electric vehicles will be […]



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administration

Biden Administration Faces Daunting Task of Rebuilding US Economic Diplomacy

Biden Administration Faces Daunting Task of Rebuilding US Economic Diplomacy Biden Administration Faces Daunting Task of Rebuilding US Economic Diplomacy
ferrard Wed, 12/09/2020 - 14:49

East-West Wire

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News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

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East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore





administration

Senior Administration and Communications Assistant

ADB has a vacancy for the position of Senior Administration and Communications Assistant in the Strategy, Policy and Partnerships Department. The deadline for submitting applications is on 26-NOV-2024.




administration

South Asia Subregional Economic Cooperation Customs Administration Reform and Modernization Project




administration

Obama Administration Offers New Rules for Religious Objections to Health Care Law

Title: Obama Administration Offers New Rules for Religious Objections to Health Care Law
Category: Health News
Created: 8/25/2014 9:35:00 AM
Last Editorial Review: 8/25/2014 12:00:00 AM




administration

Alternative Reinforcers Enhance the Effects of Opioid Antagonists, but Not Agonists, on Oxycodone Choice Self-Administration in Nonhuman Primates [Behavioral Pharmacology]

Clinical reports suggest that the most effective strategies for managing opioid use disorder comprise a comprehensive treatment program of both pharmacological and nonpharmacological approaches. However, the conditions under which these combinations are most effective are not well characterized. This study examined whether the presence of an alternative reinforcer could alter the efficacy of Food and Drug Administration–approved opioid antagonist or agonist medications, as well as the nonopioid flumazenil, in decreasing oxycodone choice self-administration in nonhuman primates. Adult squirrel monkeys (n = 7; four females) responded under concurrent second-order fixed-ratio (FR)-3(FR5:S);TO45s schedules of reinforcement for intravenous oxycodone (0.1 mg/kg) or saline on one lever and 30% sweetened condensed milk or water on the other. Doses of naltrexone (0.00032–1.0 mg/kg), nalbuphine (0.32–10 mg/kg), buprenorphine (0.0032–0.032 mg/kg), methadone (0.32–1.0 mg/kg), or flumazenil (1–3.2 mg/kg) were administered intramuscularly prior to oxycodone self-administration sessions that occurred with either milk or water as the alternative. Naltrexone, a μ-opioid receptor antagonist, was >30-fold more potent when milk was available compared with water and abolished oxycodone intake (injections/session) while concomitantly increasing milk deliveries at the highest dose tested. Pretreatment with the low-efficacy μ-agonist nalbuphine was most effective in the presence of milk compared with water, decreasing oxycodone preference to <50% of control values. The higher efficacy μ-agonists, methadone and buprenorphine, and the benzodiazepine antagonist flumazenil did not appreciably alter the reinforcing potency of oxycodone under either condition. These results suggest that antagonist medications used in combination with alternative reinforcers may be an effective strategy to curtail opioid abuse–related behaviors.

SIGNIFICANCE STATEMENT

Clinical treatment programs for opioid use disorder use a combination of pharmacological and nonpharmacological approaches. However, the conditions under which these combinations are most effective have not been fully characterized. This study examined whether the effectiveness of μ-opioid medications to decrease oxycodone self-administration is altered in the presence of an alternative reinforcer. The results suggest that alternative reinforcers enhance the effects of antagonist or low-efficacy partial agonists, suggesting they may be a more effective strategy to curtail opioid use.




administration

Chronic Administration of Cannabinoid Agonists ACEA, AM1241, and CP55,940 Induce Sex-Specific Differences in Tolerance and Sex Hormone Changes in a Chemotherapy-Induced Peripheral Neuropathy [Special Section: Cannabinoid Signaling in Human Health and Dise

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy treatment, routinely manifesting as increased pain sensitivity (allodynia) in distal extremities. Despite its prevalence, effective treatment options are limited. Cannabinoids are increasingly being evaluated for their ability to treat chronic pain conditions, including CIPN. While previous studies have revealed sex differences in cannabinoid-mediated antinociception in acute and chronic pain models, there is a paucity of studies addressing potential sex differences in the response of CIPN to cannabinoid treatment. Therefore, we evaluated the long-term antiallodynic efficacy of cannabinoid receptor type 1 (CB1)-selective, cannabinoid receptor type 2 (CB2)-selective, and CB1/CB2 mixed agonists in the cisplatin CIPN model, using both male and female mice. CB1 selective agonism was observed to have sex differences in the development of tolerance to antiallodynic effects, with females developing tolerance more rapidly than males, while the antiallodynic effects of selective CB2 agonism lacked tolerance development. Compound-specific changes to the female estrous cycle and female plasma estradiol levels were noted, with CB1 selective agonism decreasing plasma estradiol while CB2 selective agonism increased plasma estradiol. Chronic administration of a mixed CB1/CB2 agonist resulted in increased mRNA expression of proinflammatory cytokines and endocannabinoid regulatory enzymes in female spinal cord tissue. Ovarian tissue was noted to have proinflammatory cytokine mRNA expression following administration of a CB2 acting compound while selective CB1 agonism resulted in decreased proinflammatory cytokines and endocannabinoid regulatory enzymes in testes. These results support the need for further investigation into the role of sex and sex hormones signaling in pain and cannabinoid-mediated antinociceptive effects.

SIGNIFICANCE STATEMENT

CIPN is a common side effect of chemotherapy. We have found that both CB1 and CB2 receptor agonism produce antinociceptive effects in a cisplatin CIPN model. We observed that tolerance to CB1-mediated antinociception developed faster in females and did not develop for CB2-mediated antinociception. Additionally, we found contrasting roles for CB1/CB2 receptors in the regulation of plasma estradiol in females, with CB1 agonism attenuating estradiol and CB2 agonism enhancing estradiol. These findings support the exploration of cannabinoid agonists for CIPN.




administration

Trump Builds New Administration

Friday on the RealClearPolitics radio show -- weeknights at 6:00 p.m. on SiriusXM's POTUS Channel 124 and then on Apple, Spotify, and here on our website -- Tom Bevan, Andrew Walworth, and Carl Cannon look at the latest count to determine the final popular vote and House majority.




administration

RFK Jr. launches online forum to crowdsource names for 4,000 Trump administration nominees

Robert F. Kennedy Jr. launched a "Nominees for the People" forum to crowdsource 4,000 positions in the Trump administration to Make America Healthy Again.



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administration

Fox News Politics: Administration of Allies

The Fox News Politics newsletter, with the latest updates on the Trump transition, exclusive interviews and more Fox News politics content.



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administration

Biden-Harris Administration Decides Not to Cut Arms to Israel, After Threat


The State Department said Tuesday that the Biden-Harris administration would not cut off weapons supplies to Israel in reaction to what it said was a declining humanitarian situation in the Gaza Strip, due to Israeli mitigation efforts.

The post Biden-Harris Administration Decides Not to Cut Arms to Israel, After Threat appeared first on Breitbart.




administration

Donald Trump's Administration Takes Shape After 15 Official or Expected Picks


President-elect Donald Trump has made many selections to lead his administration as his transition gets underway, ranging from chief of staff to head of the Environmental Protection Agency (EPA). At the same time, a number of crucial positions have yet to be filled just one week removed from the landslide election.

The post Donald Trump’s Administration Takes Shape After 15 Official or Expected Picks appeared first on Breitbart.




administration

Administration Trump: un «faucon» anti-Chine comme secrétaire d'État, une «tueuse de chiens» à la Sécurité intérieure

Un «faucon» anti-Chine à la diplomatie, une gouverneure «tueuse de chiens» à la sécurité intérieure.




administration

Trump’s Administration Will Attack Health Care from Multiple Angles

The new Trump administration is likely to reduce subsidies for Affordable Care Act insurance plans and roll back Medicaid coverage. Public health authorities worry that antivaccine activist Robert F. Kennedy, Jr., will be empowered




administration

Trump Administration Likely to Repeal Methane Leak Penalty

A fee created to push oil and gas companies to plug methane leaks could be axed by the incoming Trump administration, hampering efforts to curb the potent greenhouse gas




administration

Biden Administration Should Prioritize Fight Against Superbugs

The Pew Charitable Trusts joined dozens of research, health care, and nonprofit stakeholders in urging President-elect Joe Biden to prioritize and strengthen the national response to antibiotic resistance.




administration

To Enhance National Security, the Biden Administration Will Have to Trim an Exorbitant Defense Wish List

David Kearn argues that even in the absence of restrictive resource and budgetary constraints, a focus on identifying and achieving concrete objectives that will position the United States and its allies to effectively deter aggression in critical regional flashpoints should be the priority given the stressed nature of the defense industrial base and the nuclear enterprise.






administration

Elon Musk Might Have a New Role in Donald Trump’s Administration: But What Is It?

Efforts to shape the policies of President-elect Donald Trump through Elon Musk are already underway. On Friday, Americans for Responsible Innovation (ARI), a nonprofit AI advocacy group, initiated a public petition urging Trump to appoint Musk as his special adviser on




administration

Elon Musk Joins Trump Administration, But Not in the AI Role You'd Expect

In a surprising twist, Elon Musk is joining the Trump administration: not to advise on artificial intelligence or space innovation, but to lead an ambitious new project focused on government efficiency. Alongside entrepreneur Vivek Ramaswamy, Musk will head up the Department




administration

Tax-News.com: Hong Kong Tables Tax Law Administration Bill

Hong Kong tabled the Inland Revenue (Amendment) (Miscellaneous Provisions) Bill 2021 in parliament on March 24.




administration

Tax-News.com: Hong Kong Tables Tax Law Administration Bill

Hong Kong tabled the Inland Revenue (Amendment) (Miscellaneous Provisions) Bill 2021 in parliament on March 24.




administration

Tax-News.com: BVI To Launch New Tax Administration Platform

The British Virgin Islands' Inland Revenue Department is to introduce a new platform from early next year to automate the administration of all taxes and licenses.




administration

New Approach to Abortion Care: Administration of Misoprostol at Home

Women take two types of pills for abortion during their pregnancy: medlinkmisoprostol/medlink, which causes the womb to contract, and medlinkmifepristone/medlink,




administration

Oramed Pharmaceuticals Reports Results in Phase 2b Trial of Oral Insulin Administration to Type 2 Diabetes Patients

Oramed Pharmaceuticals Reports Results in Phase 2b Trial of Oral Insulin Administration to Type 2 Diabetes Patients




administration

Sandata Chosen to Implement Florida Agency for Health Care Administration Telephonic Home Health Project

Sandata Chosen to Implement Florida Agency for Health Care Administration Telephonic Home Health Project




administration

New York Governor Kathy Hochul Explores Reviving Congestion Pricing Toll Ahead of Trump Administration

New York Governor Kathy Hochul explores reviving a USD 15 congestion pricing toll for Manhattan before President-elect Trump takes office.




administration

Gavin Newsom Engages with Biden Administration on Climate Policies and Disaster Relief in Washington

California Governor Gavin Newsom visits Washington to discuss zero-emission vehicles, disaster relief, and state climate rules with the Biden administration.




administration

Trump's First Week as President-Elect: Focus on Administration Building at Mar-a-Lago

Donald Trump spends his first week as president-elect at Mar-a-Lago, focusing on building his administration and reconnecting with foreign leaders.




administration

Elon Musk And Vivek Ramaswamy To Head New 'Department Of Government Efficiency' Under Trump Administration

The two will head the newly formed Department of Government Efficiency in the upcoming Trump administration, set to begin in January 2025.  




administration

Structural optimization of icaritin for advanced cancer: novel carbamates via oral administration

New J. Chem., 2024, Advance Article
DOI: 10.1039/D3NJ05723B, Paper
Fengxiao Li, Weiping Wang, Jiaqi Fan, Yixiu Zhai, Jiaming Zhang, Tianhong Zhang, Qikun Jiang
Carbamates of icaritin (3N-Me and 3N-Et) are synthesized first to overcome the challenge of the phase II metabolism of ICT. 3N-Me has potential as a novel advanced cancer treatment agent via oral administration in the future.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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