DAMASAK, Nigeria — When Boko Haram launched an insurgency in northeastern Nigeria in 2010, Abdulhameed Salisu packed his bag and fled from his hometown of Damasak in the country's battered Borno state.  The 45-year-old father of seven came back with his family early last year. They are among thousands of Nigerians taken back from displacement camps to their villages, hometowns or newly built settlements known as “host communities” under a resettlement program that analysts say is being rushed to suggest the conflict with the Islamic militants is nearly over.  Across Borno, dozens of displacement camps have been shut down, with authorities claiming they are no longer needed and that most places from where the displaced fled are now safe.  But many of the displaced say it’s not safe to go back.  Boko Haram — Nigeria’s homegrown jihadis — took up arms in 2009 to fight against Western education and impose their radical version of Islamic law, or Sharia. The conflict, now Africa's longest struggle with militancy, has spilled into Nigeria's northern neighbors.  Some 35,000 civilians have been killed and more than 2 million have been displaced in the northeastern region, according to U.N. numbers. The 2014 kidnapping of 276 schoolgirls by Boko Haram in the village of Chibok in Borno state — the epicenter of the conflict — shocked the world.  Borno state alone has nearly 900,000 internally displaced people in displacement camps, with many others absorbed in local communities. So far this year, at least 1,600 civilians have been killed in militant attacks in Borno state, according to the Armed Conflict Location and Event Data Project, a U.S.-based nonprofit.  And in a state where at least 70% of the population depends on agriculture, dozens of farmers have also been killed by the extremists or abducted from their farmland in the last year.  In May, hundreds of hostages, mostly women and children who were held captive for months or years by Boko Haram were rescued from a forest enclave and handed over to authorities, the army said.  In September, at least 100 villagers were killed by suspected Boko Haram militants who opened fire on a market, on worshippers and in people’s homes in the Tarmuwa council area of the neighboring Yobe state, west of Borno.  Analysts say that a forced resettlement could endanger the local population as there is still inadequate security across the hard-hit region.  Salisu says he wastes away his days in a resettlement camp in Damasak, a garrison town in Borno state of about 200,000 residents, close to the border with Niger.  Food is getting increasingly difficult to come by and Salisu depends on handouts from the World Food Program and other aid organizations. He longs to find work.  “We are begging the government to at least find us a means of livelihood instead of staying idle and waiting for whenever food comes,” he said.  On a visit last week to Damasak, Cindy McCain, the WFP chief, pledged the world would not abandon the Nigerian people as she called for more funding to support her agency's aid operations.  “We are going to stay here and do the very best we can to end hunger,” McCain told The Associated Press as she acknowledged the funding shortages. “How do I take food from the hungry and give it to the starving,” she said.  Resettlement usually involves the displaced being taken in military trucks back to their villages or “host communities." The Borno state government has promised to provide returnees with essentials to help them integrate into these areas, supported by aid groups.  The government says the displacement camps are no longer sustainable.  “What we need now is ... durable solutions,” Borno governor Babagana Zulum told McCain during her visit.  As the resettlement got underway, one in five displaced persons stayed back in Maiduguri, the Borno state capital, and nearby towns but were left without any support for local integration, the Global Protection Cluster, a network of non-government organizations and U.N. agencies, said last December.  Many others have crossed the border to the north, to settle as refugees in neighboring Niger, Chad or Cameroon. The three countries have registered at least 52,000 Nigerian refugees since January 2023, according to the U.N. refugee agency — nearly twice the number registered in the 22 months before that.  A rushed closure of displacement camps and forced resettlement puts the displaced people at risk again from militants still active in their home areas — or forces them to “cut deals” with jihadis to be able to farm or fish, the International Crisis Group warned in a report earlier this year.  That could make the extremists consolidate their presence in those areas, the group warned. Boko Haram, which in 2016 split into two main factions, continues to ambush security convoys and raid villages.  Abubakar Kawu Monguno, head of the Center for Disaster Risk Management at the University of Maiduguri, said the best option is for government forces to intensify their campaign to eliminate the militants or “push them to surrender.”  After not being able to access their farms because of rampant attacks by militants, some farmers in Damasak and other parts of Mobbar district returned to work their land last year, armed with seedlings provided by the government.  Salisu was one of them.  Then a major flood struck in September, collapsing a key dam and submerging about 40% of Maiduguri's territory. Thirty people were killed and more than a million others were affected, authorities said.  Farms that feed the state were ruined, including Salisu's. His hopes for a good rice harvest were washed away. Now he lines up to get food at a Damasak food hub.  “Since Boko Haram started, everything else stopped here," he said. “There is nothing on the ground and there are no jobs.”  Maryam Abdullahi also lined up at a WFP hub in Damasak with other women, waiting for bags of rice and other food items she desperately needs for her family of eight. Her youngest is 6 years old.  The donations barely last halfway through the month, she said, but she still waited in the scorching heat.  What little money she has she uses to buy yams to fry and sell to sustain her family, but it’s nowhere enough. Her only wish is to be able to get a “proper job” so she and her children would feel safe, she said.  “We either eat in the morning for strength for the rest of the day or ... we eat only at night,” Abdullahi said. 

Lita Cohen said she was "very upset with that recent Trump ad that stereotypes Jewish people.”

About 50 settlers gathered to attack the IDF soldiers, injuring one soldier who was taken to hospital with head injuries.

Hegseth, if confirmed, could aid Trump's promise to remove generals he believes prioritize progressive diversity policies opposed by conservatives.

Slackliners set world record, balancing at 2,500 metres high between hot air balloons

World record set at extreme Antarctica Ice Ultra race

Dutch police disperse people from streets after Amsterdam tram set on fire

Wall Street firms are expected to pay heftier bonuses for this year, the first increase since a bumper year in 2021, according to a report by compensation consultancy Johnson Associates. Payouts will probably rise after financiers benefited from several factors in recent months: a recovery in dealmaking, the Federal Reserve cutting interest rates and equity […]

U.S. President-elect Donald Trump on Tuesday named Elon Musk to a role aimed at creating a more efficient government, handing even more influence to the world’s richest man who donated millions of dollars to helping Trump get elected. Pete Hegseth, a Fox News commentator and veteran has been picked for the post of secretary of state. […]

Colorado Democrats looked set to maintain their supermajority in the state House as of Wednesday afternoon, though they fell short of reaching the same threshold in the Senate.

India’s federal power minister on Tuesday asked the states that are away from coal resources to consider setting up nuclear-based power plants, besides identifying and listing the power utilities to meet investments to support growing power demand.

The Indian government in its federal budget this year had proposed to partner with private players to develop small nuclear reactors to increase the amount of electricity from sources that do not produce carbon dioxide emissions.

States should consider setting up nuclear power plants at the sites where coal-based thermal power plants have completed their life, Manohar Lal, the country’s power minister, told states as per a government statement.

India’s stringent nuclear compensation laws have hampered talks with foreign power plant builders such as General Electric GE.N and Westinghouse.

The country, which currently has about 8 gigawatts of nuclear capacity, aims to increase it to 20 GW by 2032.

The minister also asked the states to identify and list their power utilities in the country’s stock exchange to meet increasing investment demand in the power sector as well as improve the transmission system to add more renewable capacity.

India has pledged to achieve a net zero carbon emission target by 2070 and has a target of 500 GW of renewable energy by 2030.

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Marmosets are the first non-human primates shown to use personalised signifiers to refer to each other – the discovery could help us better understand how language evolved

Photographer Matjaz Krivic has been charting the effects of lithium mining on locals in the world's largest salt flat in Bolivia since 2016

Mysterious green sunsets were reported after the massive eruption of Krakatoa in 1883 – now simulations show how they were created and just how rare they are

This year could bring up to 25 named tropical storms in the Atlantic Ocean due to a shift to La Niña conditions, says the US National Oceanic and Atmospheric Administration

Smoke from wildfires burning in Canada and Mexico is already worsening air quality in the US, but some signs suggest clearer skies than last year

The focus is on finance at the UN climate summit in Baku, Azerbaijan, this month, but countries are a long way from any kind of consensus

This year’s average global temperature is almost certain to exceed 1.5°C above pre-industrial times – a milestone that should spur urgent action, say climate scientists

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BACKGROUND:Beneficial effects of breathing at FIO2 < 0.21 on disease outcomes have been reported in previous preclinical and clinical studies. However, the safety and intra-hospital feasibility of breathing hypoxic gas for 5 d have not been established. In this study, we examined the physiologic effects of breathing a gas mixture with FIO2 as low as 0.11 in 5 healthy volunteers.METHODS:All 5 subjects completed the study, spending 5 consecutive days in a hypoxic tent, where the ambient oxygen level was lowered in a stepwise manner over 5 d, from FIO2 of 0.16 on the first day to FIO2 of 0.11 on the fifth day of the study. All the subjects returned to an environment at room air on the sixth day. The subjects' SpO2, heart rate, and breathing frequency were continuously recorded, along with daily blood sampling, neurologic evaluations, transthoracic echocardiography, and mental status assessments.RESULTS:Breathing hypoxia concentration dependently caused profound physiologic changes, including decreased SpO2 and increased heart rate. At FIO2 of 0.14, the mean SpO2 was 92%; at FIO2 of 0.13, the mean SpO2 was 93%; at FIO2 of 0.12, the mean SpO2 was 88%; at FIO2 of 0.11, the mean SpO2 was 85%; and, finally, at an FIO2 of 0.21, the mean SpO2 was 98%. These changes were accompanied by increased erythropoietin levels and reticulocyte counts in blood. All 5 subjects concluded the study with no adverse events. No subjects exhibited signs of mental status changes or pulmonary hypertension.CONCLUSIONS:Results of the current physiologic study suggests that, within a hospital setting, delivering FIO2 as low as 0.11 is feasible and safe in healthy subjects, and provides the foundation for future studies in which therapeutic effects of hypoxia breathing are tested.

The aim of this study was to validate a previously developed deep learning model in 5 independent clinical trials. The predictive performance of this model was compared with the international prognostic index (IPI) and 2 models incorporating radiomic PET/CT features (clinical PET and PET models). Methods: In total, 1,132 diffuse large B-cell lymphoma patients were included: 296 for training and 836 for external validation. The primary outcome was 2-y time to progression. The deep learning model was trained on maximum-intensity projections from PET/CT scans. The clinical PET model included metabolic tumor volume, maximum distance from the bulkiest lesion to another lesion, SUV_peak, age, and performance status. The PET model included metabolic tumor volume, maximum distance from the bulkiest lesion to another lesion, and SUV_peak. Model performance was assessed using the area under the curve (AUC) and Kaplan–Meier curves. Results: The IPI yielded an AUC of 0.60 on all external data. The deep learning model yielded a significantly higher AUC of 0.66 (P < 0.01). For each individual clinical trial, the model was consistently better than IPI. Radiomic model AUCs remained higher for all clinical trials. The deep learning and clinical PET models showed equivalent performance (AUC, 0.69; P > 0.05). The PET model yielded the highest AUC of all models (AUC, 0.71; P < 0.05). Conclusion: The deep learning model predicted outcome in all trials with a higher performance than IPI and better survival curve separation. This model can predict treatment outcome in diffuse large B-cell lymphoma without tumor delineation but at the cost of a lower prognostic performance than with radiomics.

The diagnosis of maturity-onset diabetes of the young (MODY), a monogenic form of diabetes mellitus caused by a mutation in a single gene, is often uncertain until genetic testing is performed. We report a 13-yr-old Korean boy who was initially diagnosed with type 2 diabetes (T2DM). MODY was suspected because of his nonobese body habitus and family history of multiple affected members. Targeted panel sequencing of all MODY-related genes was performed using the NextSeq 550Dx platform (Illumina). Sanger sequencing was performed using blood samples from the parents, siblings, and other relatives. A frameshift variant in the 3' region of the last exon of PDX1 was detected in the patient and his family members with diabetes. PP1_Moderate criterion was applied and this variant was confirmed to be the genetic cause of diabetes in the family and classified as likely pathogenic. The study highlights the importance of genetic testing for nonobese, early-onset diabetic patients with multiple affected family members. Increased awareness and aggressive genetic testing for MODY are needed.

For many severe lung diseases, non-invasive biomarkers from imaging could improve early detection of lung injury or disease onset, establish a diagnosis, or help follow-up disease progression and treatment strategies. Imaging of the thorax and lung is challenging due to its size, respiration movement, transferred cardiac pulsation, vast density range and gravitation sensitivity. However, there is extensive ongoing research in this fast-evolving field. Recent improvements in spatial imaging have allowed us to study the three-dimensional structure of the lung, providing both spatial architecture and transcriptomic information at single-cell resolution. This fast progression, however, comes with several challenges, including significant image file storage and network capacity issues, increased costs, data processing and analysis, the role of artificial intelligence and machine learning, and mechanisms to combine several modalities. In this review, we provide an overview of advances and current issues in the field of spatial lung imaging.

Danielle Smith says she is “100 per cent committed” to a leaked plan to replace Alberta Health Services with new health boards, agencies, bureaucracy, all directed out of her office.

The post UCP set to announce plan to bust up AHS appeared first on rabble.ca.

3D Scotland are an innovative, Glasgow-based company who specialise in the design and manufacture of unique chess sets. Their sets have proved extremely popular as Christmas gifts, graduation gifts, fathers’ day gifts and everything in between.

Up to 700 international competitors and crew will flock to Benalla as the event returns to Australia after 30 years.

Nintendo announced it will host a Super Nintendo World Direct livestream on Monday, November 11 at 2:00 pm PT / 5:00 pm ET. You will be able to watch it on YouTube.

The Direct will be roughly 10 minutes and feature the Donkey Kong Country area of Super Nintendo World at Universal Studios Japan.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463031/super-nintendo-world-direct-set-for-november-11/

The Polaris Dawn mission will include the first ever civilian spacewalk, and with a new spacesuit and no airlock, it may also be the most dangerous spacewalk ever

The European Space Agency is sending a probe to get a closer look at the asteroid Dimorphos, which had its orbit altered by NASA’s DART mission in 2022

A 6000-kilogram spacecraft will embark on a six-year journey to Jupiter to explore whether its icy moon Europa has the conditions to support life

In Still Wakes the Deep, you play as a Glaswegian electrician on a 1970s oil rig. The well-crafted setting gives way to horror, but I wish I could linger in mundanity for longer, says Jacob Aron

Roads with variable speed limits, designed to manage traffic flow, are normally adjusted according to simple rules, but a 27-kilometre section of the I-24 freeway near Nashville, Tennessee, is now overseen by an artificial intelligence

Other Democrats lambasted him. The Tufts political science department spurned him. But Moulton is raising concerns the left needs to take seriously.

The Pokemon Company is teaming up with content creators to stage a 24-hour unboxing live stream for its new Scarlet & Violet - Surging Sparks card set as you Gotta Catch 'Em All

Senate Republicans on Wednesday will elect a new party leader for the first time in nearly two decades.

President-elect Donald Trump said he will nominate Fox News host Pete Hegseth to be secretary of defense.

The Massimo Modular E9 is a sleek, smart and comfy tiny home in 409 square feet. Tech expert Kurt “CyberGuy" Knutsson takes a closer look at what the future of housing might look like.

Former Fox News host Pete Hegseth has been selected by President-elect Trump to serve as his secretary of defense. Hegseth served in the U.S. Army.