Commonly used model teeth are so far uniform in color and hardness. There is no discrimination between enamel and dentin part of a tooth. This condition makes it difficult to train a preparation technique, which is adapted to real tooth substance. The aim of this study was to design and establish a 3D printed tooth with different layers for enamel and dentin for education in crown preparation. A printable tooth with different layers for enamel and dentin was designed, and all 38 fourth-year dental students in the first clinical course in prosthodontics and 30 experienced dentists were trained during a voluntary hands-on course in 2019. Prior to the study, the students had used standard model teeth and real-teeth models in their preclinical education. They had experience in caries removal and preparation on real patients. The perceived benefits of the 3D printed tooth were evaluated by a questionnaire. All individuals in both groups completed the questionnaire, for a 100% response rate. The results showed that the printed tooth was given an overall mean grade of 2.3 (students) and 2.0 (experts) on a scale from 1=excellent to 5=poor. The difference in hardness between the dentin and enamel layer was given a mean of 2.4 (students and experts) and the difference in color a 1.7 (students) and 1.8 (experts). The tooth model with the prepared tooth illustrating an ideal preparation was graded 1.6 (students and experts). In this study, the students had the opportunity to learn a correct crown preparation on a printed tooth with different material properties for enamel and dentin. The learning effect with this tooth model was rated as good on the questionnaire by both students and expert dentists.

⁶⁸Ga-labeled urea-based inhibitors of the prostate-specific membrane antigen (PSMA), such as ⁶⁸Ga-PSMA-11, are promising small molecules for targeting prostate cancer (PCa). Although this radiopharmaceutical was produced mostly by means of manual synthesis and automated synthesis modules, a sterile cold kit was recently introduced. The aim of our study was to evaluate the image quality of ⁶⁸Ga-PSMA-11 PET/CT (PSMA-PET) in a population of PCa patients after the injection of comparable activities of ⁶⁸Ga-PSMA-11 obtained with the 2 different synthetic procedures. A secondary aim was to identify secondary factors that may have an impact on image quality and, thus, final interpretation. Methods: Two different groups of 100 consecutive PCa patients who underwent PSMA-PET were included in the study. The first group of patients was imaged with ⁶⁸Ga-PSMA-11 obtained using synthesis modules, whereas the second group’s tracer activity was synthesized using a sterile cold kit. All PET images were independently reviewed by 2 nuclear medicine diagnosticians with at least 2 y of experience in PSMA-based imaging and unaware of the patients’ clinical history. The 2 reviewers independently rated the quality of each PSMA-PET scan using a 3-point Likert-type scale. In cases of discordance, the operators together reviewed the images and reached a consensus. Performance was evaluated on the basis of the expected biodistribution, lesion detection rate, and physiologic background uptake. Results: Overall, 104 of 200 (52%) PSMA-PET scans were positive for PCa-related findings. No significant differences in image quality between cold kits and synthesis modules were found (P = 0.13), although a higher proportion of images was rated as excellent by the observers for kits than for modules (45% vs. 34%). Furthermore, after image quality had been dichotomized as excellent or not excellent, multivariate regression analysis found several factors to be significantly associated with a not-excellent quality: an increase in patient age (+5 y: odds ratio [OR], 1.40; 95% confidence interval [CI], 1.12–1.75), an increase in patient weight (+5 kg: OR, 1.89; 95% CI, 1.53–2.32), an increase in ⁶⁸Ga-PSMA-11 uptake time (+10 min: OR, 1.45; 95% CI, 1.08–1.96), and a decrease in injected activity (–10 MBq: OR, 1.28; 95% CI, 1.07–1.52). Conclusion: No significant differences were identified between the 2 groups of patients undergoing PSMA-PET; therefore, we were not able to ascertain any significant influences of tracer production methodology on final scan quality. However, increased patient age, increased patient weight, decreased injected activity, and increased ⁶⁸Ga-PSMA-11 uptake time were significantly associated with an overall poorer image quality.

It all boils down to how resilient the region is, says an urban planner and designer based in Manila.

For the past two months, Katie Holliday has been cooped up alone in her Brooklyn apartment thinking longingly about an unlikely erogenous zone: the lower half of a stranger’s face. 

“I remember joking to my friend before all of this started, ‘Imagine if someone’s face becomes their most coveted body part?’” Holliday, who is 31, told The Daily Beast. “‘When someone removes their mask, is it a sign of trust? Is it like letting someone see you naked?’ I was kidding back then, but now it’s reality.”

Holliday doesn’t know exactly when it will be safe to start seeing people like she did before the pandemic began, but she’ll return to a singles scene unlike any other in history. “I’m picturing walking into a bar where everyone’s wearing masks,” she said. “I’ll meet someone whose face is covered. Are they cute or not? I don’t know!” 

Read more at The Daily Beast.

Morningside USA was supposed to be apocalypse-proof. 

A gated, stucco fortress in the southwest corner of Missouri’s Ozark mountains, Morningside is an evangelical Christian community built to rent condos right through the end of the world.

“Where are you going to go when the world's on fire? Where are you going to go? This place is for God's people and this place, we need some farmers to move here,” Morningside’s founder, the disgraced doomsday televangelist Jim Bakker, said in a May 2018 sermon. “Did you know people from the government, from NASA, research from so many of them, they have said in their research, the safest place to live in troubled times is right here?”  

Read more at The Daily Beast.

Roboticists share what they've learned so far from DARPA's Subterranean Challenge, and how they readied their bots for the next event—the Tunnel Circuit

The B.C. Lions made sure to count every last penny when announcing a new contract for free-agent quarterback Mike Reilly ahead of the 2019 Canadian Football League season. Reilly, who had ...

The White House is making "contingency plans" for a second wave of coronavirus after emails reportedly contradict their claims that Centers for Disease Control and Prevention guidelines to safely reopen the economy were set aside because medical experts did not approve of them.

Welsh plan to reopen stores offers hope for UK-wide industry closed in prime sales season

Garden centres are preparing for a surge in plant and flower sales that could help salvage a catastrophic year for the horticulture industry.

The UK’s 2,000 garden centres and nurseries were forced to close in March because, unlike DIY chains such as B&Q and Homebase, they were not granted “essential” retailer status. The shutdown came at a critical time of year, with 70% of sales rung up in spring, forcing devastated growers to throw away millions of plants.

Future Navy SEALs will conduct combat scenarios six-feet apart, emulate high-risk combat scenarios, study in smaller classrooms and be directed by megaphones at farther distances, because more candidates for the special operations unit are again competing, training and preparing for war following temporary delays caused by COVID 19.

Siemens is preparing for a prolonged economic trough triggered by the COVID-19 pandemic, Chief Executive Joe Kaeser told CNBC on Friday after releasing fiscal second-quarter results.

Coronavirus: the symptoms Read our LIVE updates on the coronavirus here

From being "too slow" to act on testing, PPE and the lockdown, to care home deaths and Boris Johnson's attendance at meetings, ministers are caught in a storm.

Ministers were reportedly warned to prepare for a pandemic virus last year, according to a leaked document.

Boris Johnson is preparing a plan for the UK's escape from lockdown after declaring the nation has "past the peak" of its coronavirus outbreak.

Boris Johnson wants people in the UK to be back at work by the end of May if coronavirus cases are low enough, it has been reported.

Boris Johnson has said doctors prepared to announce his death as he battled coronavirus in intensive care.

The Royal Hospital Chelsea today revealed that nine of its residents had died from the coronavirus.

The first changes to the UK's coronavirus lockdown will be "small" and "very carefully monitored" when the Prime Minister reveals his "roadmap" on Sunday.

The UK was ill-prepared to deal with a health pandemic, according to a secret Whitehall document produced years before the coronavirus outbreak.

The nation is preparing to celebrate the 75th anniversary of Victory in Europe (VE) Day , with the Queen set to make a historic address to mark the occasion.

Cabinet Secretary Oliver Dowden admitted on Friday morning that the lockdown is facing a major test from the sunny weekend ahead.

Peer review moves to Twitter, muddling public health information.

Living on a 10-acre plot of land 100 kilometres outside Toronto, David Stevens thought he and his family were well prepared to ride out the COVID-19 quarantine. But after a call from his mother, he learned that even the best laid plans can go wrong.

Adam Silver outlined a potentially grim future for the NBA in a call with players, calling the pandemic the "single greatest challenge of all our lives."

Finlay was married to Joe Exotic during filming of 'Tiger King'

Wales defender James Lawrence has offered an insight into how German football is reacting to coronavirus as players begin to return to training.

Manchester United are aiming to resume full training next month as Premier League clubs work towards a return to action in June.

Watford have overhauled their Vicarage Road stadium to support their neighbours at Watford General Hospital through the coronavirus crisis.

Paris Saint-Germain will play their remaining home Champions League matches overseas if it is not possible to do so in France, according to president Nasser Al-Khelaifi.

Crystal Palace are preparing for an imminent return to training as the Eagles begin to work back towards a normal routine.

Jadon Sancho has returned to training with Borussia Dortmund with German football edging closer to a return following the coronavirus shutdown.

Barcelona and Real Madrid players will be back at their club's installations for tests on Wednesday as LaLiga teams prepare for a return to training this week.

West Ham's goalkeepers are using the extra time afforded by the coronavirus lockdown to sharpen their minds.

Tottenham have been handed a major boost in their attempts to sign Thomas Meunier with reports in France claiming that the Belgian will not be signing a new contract with PSG.

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The Pentagon can't prevent a pandemic.

Thousands of years of Jewish practice meet high-end architecture in Succah by the Sea a public art event in Bondi.

The win means new, steady work for the company's Puget Sound region site at a time the region is losing tens of thousands of layoffs in aerospace manufacturing.

It helps to have a former big-leaguer as a dad if you want to stay sharp during a pandemic.

Simi Valley two-sport athlete Chase Aurand learned a valuable history lesson amid the coronavirus outbreak: 'Don't take going to practice for granted.'

With restrictions of the COVID-19 pandemic, the Chargers are tasked with preparing prized rookie quarterback Justin Herbert virtually.

The UK government made key failings in their strategic preparations and emergency response to coronavirus and this, in turn, undermined the NHS's ability to cope with the crisis.These are the findings recently published in a research paper for the Journal of Risk Research by academics from Cass Business School, Glasgow Caledonian University, Vlerick Business School, and Nottingham University Business School.

The COVID-19 pandemic has revealed major deficiencies and inequities in the US healthcare system, shining a spotlight on improvements that must be made to steel the country for future disasters, argues Maia.

One in twenty businesses said they would be unable to viably operate as long as social distances measures are still enforced.