nl Healing Day 24: Love is not the Only Answer By www.avjobs.com Published On :: Fri, 4 Aug 2023 03:39:57 -0400 Healing Day 24: Love Is Not The Only Answer Soojin Jun, PharmD... Full Article life-lessons space spirituality inspiration poetry
nl [Turkish] Osmanlıda ve Cumhuriyet’te Asker ve Sivil Bürokrat... By www.atour.com Published On :: Sat, 13 Jan 2024 21:08:00 UT [Turkish] Osmanlıda ve Cumhuriyet’te Asker ve Sivil Bürokratların Kaleme Aldığı Asur ve Ermeni Raporları I Full Article Government and Political Information
nl Biden's embrace of Saudi prince shows that his only principle was defeating Trump By www.washingtonexaminer.com Published On :: Fri, 09 Jul 2021 04:00:47 GMT At this point, it may be fair to say President Joe Biden’s criticisms of his predecessor have nothing to do with principles. It was all politics, all the way down. Full Article
nl CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients By scienceblogs.com Published On :: Thu, 06 Feb 2020 19:52:53 +0000 CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients In the first-ever (sanctioned) investigational use of multiple edits to the human genome, a study found that cells edited in three specific ways and then removed from patients and brought back into the lab setting were able to kill cancer months after their original manufacturing and infusion. This is the first U.S. clinical trial to test the gene editing approach in humans, and the publication of this new data today follows on the initial report last year that researchers were able to use CRISPR/Cas9 technology to successfully edit three cancer patients' immune cells. The ongoing study is a cooperative between Tmunity Therapeutics, the Parker Institute for Cancer Immunotherapy, and the University of Pennsylvania. Patients on this trial were treated by Edward A. Stadtmauer, MD, section chief of Hematologic Malignancies at Penn, co-lead author on the study. The approach in this study is closely related to CAR T cell therapy, in which patient immune cells are engineered to fight cancer, but it has some key differences. Just like CAR T, researchers in this study began by collecting a patient's T cells from blood. However, instead of arming these cells with a receptor against a protein such as CD19, the team first used CRISPR/Cas9 editing to remove three genes. The first two edits removed a T cell's natural receptors so they can be reprogrammed to express a synthetic T cell receptor, allowing these cells to seek out and destroy tumors. The third edit removed PD-1, a natural checkpoint that sometimes blocks T cells from doing their job. Once the three genes are knocked out, a fourth genetic modification was accomplished using a lentivirus to insert the cancer-specific synthetic T cell receptor, which tells the edited T cells to target an antigen called NY-ESO-1. Previously published data show these cells typically survive for less than a week, but this new analysis shows the edited cells used in this study persisted, with the longest follow up at nine months. Several months after the infusion, researchers drew more blood and isolated the CRISPR-edited cells for study. When brought back into the lab setting, the cells were still able to kill tumors. The CRISPR-edited T cells used in this study are not active on their own like CAR T cells. Instead, they require the cooperation of a molecule known as HLA-A*02:01, which is only expressed in a subset of patients. This means that patients had to be screened ahead of time to make sure they were a match for the approach. Participants who met the requirements received other clinically-indicated therapy as needed while they waited for their cells to be manufactured. Once that process was completed, all three patients received the gene-edited cells in a single infusion after a short course of chemotherapy. Analysis of blood samples revealed that all three participants had the CRISPR-edited T cells take root and thrive in the patients. While none responded to the therapy, there were no treatment-related serious adverse events. CRISPR technology has not previously been tested in humans in the U.S. so the research team had to move through a comprehensive and rigorous series of institutional and federal regulatory approval steps, including approval by the National Institutes of Health's Recombinant DNA Research Advisory Committee and review by the U.S. Food and Drug Administration, as well as Penn's institutional review board and institutional biosafety committee. The entire process required more than two years. Researchers say these new data will open the door to later stage studies to investigate and extend this approach to a broader field beyond cancer, several of which are already planned at Penn. sb admin Thu, 02/06/2020 - 14:52 Categories Life Sciences Full Article
nl Washington's streak of 718 days without snow unlikely to be broken despite East Coast bracing for storm By www.washingtonexaminer.com Published On :: Fri, 05 Jan 2024 22:20:38 GMT Washington, D.C.'s streak of 718 days without heavy snow will not likely be broken anytime soon, even as the rest of the East Coast prepares for a winter storm this weekend. Full Article
nl California plans to enlist AI to translate healthcare information By www.latimes.com Published On :: Mon, 17 Jun 2024 20:04:12 GMT State officials want to use artificial intelligence to translate public healthcare and social services documents and websites. But some experts worry AI may introduce errors. Full Article
nl Trump posted a fake Taylor Swift image. AI and deepfakes are only going to get worse this election cycle By www.latimes.com Published On :: Wed, 21 Aug 2024 10:00:48 GMT The surge in deepfake images and videos online of U.S. presidential candidates Donald Trump and Kamala Harris have raised questions over whether the false information could impact the election. Full Article
nl Online fraudster on the loose after bilking investors out of millions with fake inventions, websites By www.latimes.com Published On :: Thu, 5 Sep 2024 18:53:21 GMT Santa Clara County fraudster Dennis Fountaine fled sentencing last month. Fountaine was convicted of three felony counts of grand theft by fraud. He also admitted to the aggravated white-collar enhancement for defrauding four victims of over $350,000. Full Article
nl Opinion: The risks of sharing your DNA with online companies aren't a future concern. They're here now By www.latimes.com Published On :: Mon, 21 Oct 2024 10:06:55 GMT Turmoil at 23andMe, and a lawsuit alleging that GEDmatch shares data with Facebook, highlights how far your genetic information could travel without your consent. Full Article
nl To keep deepfakes from infiltrating its site, Yahoo News enlists help from McAfee By www.latimes.com Published On :: Wed, 23 Oct 2024 12:00:12 GMT To buttress its defenses against bogus, AI-generated images, Yahoo News is integrating deepfake-detection technology from McAfee into its system. Full Article
nl Automating Liquid Biopsy: Unleashing New Potential in Diagnostics By www.the-scientist.com Published On :: Wed, 30 Oct 2024 19:03:43 GMT Discover how automation increases the efficiency and reliability of blood-based liquid biopsy assays. Full Article The Marketplace
nl Unlocking the Metabolic Drivers of Alzheimer’s Disease By www.the-scientist.com Published On :: Fri, 01 Nov 2024 04:00:27 GMT Cellular oxygen consumption in the brain may shed new light on Alzheimer’s disease onset, progression, and treatment. Full Article Magazine Issue
nl Seattle's Only News Quiz By www.thestranger.com Published On :: Fri, 01 Nov 2024 11:10:00 -0700 Our news quiz is back and ready to roll, just in time for... well, a week that feels like it might be kind of important! by Sally Neumann & Leah Caglio Full Article Seattle's Only News Quiz
nl Seattle's Only News Quiz By www.thestranger.com Published On :: Fri, 08 Nov 2024 09:00:00 -0800 Well, something sure has happened. And frankly, if we have to read one more fact about that man and his sycophantic oligarchical cabal, we will lose our shit. So we’re going to do some radical self-care by cooking a cauldron of Strega Nona-style pasta and writing about all the joyful things, and scraps of progress we can find. Here are some (relatively! Low bar, but it’s what we have!) GOOD things to have come out of this election. Let’s start off with Washington: our very own Big Blue House. by Sally Neumann & Leah Caglio Create your own user feedback survey Full Article Seattle's Only News Quiz
nl How to Build an Online Portfolio and Drive Traffic To It By www.rssfeedsgenerator.com Published On :: Tue, 31 Mar 2015 13:25:38 +0000 When you’re a web designer, graphic designer, or similar professional in a creative field, you have two essential tools for attracting new clients: word of mouth and a stellar portfolio. The latter can be invaluable so it’s critical that you’re able to build a strong one and drive traffic to it. Neglect these tasks and […] Full Article eBusiness Tips online marketing ideas social network marketing targeted traffic tips
nl Online media release on Internet News Bureau By www.internetnewsbureau.com Published On :: Thu, 5 Dec 2002 08:00:00 +0800 Our online media release is published on Internet News Bureau. Full Article
nl Newlook Marketing accepts PayPal online payment By www.newlook.com.sg Published On :: Thu, 22 May 2003 08:00:00 +0800 Newlook Marketing has registered a business account with PayPal, to accept all types of online payment of its online purchases. Accepted Credit Cards are Visa, MasterCard, American Express card, Discover and e-Check. Full Article
nl Online Tutorial for Navigating the Website By www.newlook.com.sg Published On :: Sat, 8 Nov 2003 08:00:00 +0800 An online tutorial that shows shoppers in a step-by-step guide to search for hosiery and socks of interest and on how to place an online order. Full Article
nl Post your comments online at the product page By www.newlook.com.sg Published On :: Tue, 17 Feb 2004 08:00:00 +0800 If you have any comments regarding the hosiery shown on the website, you are most welcome to post your comments online at any webpage showing the product details. All comment links are available at the bottom of every product page on the website. Full Article
nl Online Newsletter By www.newlook.com.sg Published On :: Thu, 6 May 2004 18:27:34 +0800 Here's our newsletter archive, for the benefit of non-registered users. Newlook Marketing periodically sends out updates and announcement (about once in 2 months) via email to registered users. Registered users may opt out from our mailing list by updating their user profile or send an email to webmaster@newlook.com.sg. Full Article
nl Election results 2024: Who won, and which races are too close to call in the Inland Northwest By www.inlander.com Published On :: Wed, 06 Nov 2024 09:48:34 -0800 While many were focused on the race for the White House, Inland Northwest contests were also largely decided on Tuesday night. With at least 31,000 ballots remaining to be counted, Spokane County voter turnout hovered around 56% of registered voters as of Tuesday, which is significantly lower than expected in a presidential election… Full Article Local News
nl Across the Inland Northwest, national and local talent comes together to deliver top-tier entertainment throughout the year By www.inlander.com Published On :: Mon, 23 Sep 2024 01:30:00 -0700 When you take stock of all the performing and fine arts offerings around the region, there's little doubt that entertainment lovers are spoiled for choice… Full Article Arts & Entertainment
nl Where I Can Find an Inlander? By www.inlander.com Published On :: Mon, 23 Mar 2020 16:28:00 -0700 We at the Inlander remain committed to keeping people informed and connected during the coronavirus outbreak, supporting our readers and local businesses in the ways we always have. We have experienced some disruption in where we distribute papers, but we're stocking and restocking thousands of copies at local Rosauers, Super 1, URM Cash & Carry, Yoke's, Albertson's and Safeway stores, plus Papa Murphy's locations, My Fresh Basket and more… Full Article News/Local News
nl The Inlander teamed up with a Rogers art teacher to paint a tribute to 2020 grads in Riverfront Park By www.inlander.com Published On :: Fri, 22 May 2020 12:52:00 -0700 As a general rule, if you start spray-painting Riverfront Park, Riverfront Park gets mad at you… Full Article News/Local News
nl Inlander Insights: Super Sparkle gets ready to say goodbye By www.inlander.com Published On :: Mon, 18 Oct 2021 10:07:00 -0700 Super Sparkle is returning to say au revoir… Full Article Music/Music News
nl Inlander Insights: Spokane String Quartet's Amanda Howard-Phillips By www.inlander.com Published On :: Wed, 17 Nov 2021 16:19:00 -0800 While there's always an impressive power hearing a full symphony fill a room with sound, there's a stirring subtlety that can only be achieved via classic music on a smaller scale. That's a sonic itch that the Spokane String Quartet is always happy to scratch. Before the Spokane String Quartet takes the stage at The Fox this Sunday for a program featuring special guest pianist Archie Chen, we caught up with violinist Amanda Howard-Phillips—who has played with the quartet since 2011 and is also second violin in the Spokane Symphony — to chat about the communal expression of string quartet music, SSQ's upcoming shows, and the unique place the group occupies in Spokane… Full Article Music/Music News
nl Inlander Insights: The Sweeplings By www.inlander.com Published On :: Fri, 08 Apr 2022 08:00:00 -0700 The folk duo with Spokane connections wrestles with grief on its new album, 'Debris.' Loss is never easy. Loss during a pandemic is even tougher… Full Article Music/Music News
nl LA-based BODYTRAFFIC brings its signature contemporary dance style to the Inland Northwest By www.inlander.com Published On :: Thu, 17 Oct 2024 01:30:00 -0700 When Tina Berkett moved from New York City to Los Angeles in 2007, she immediately noticed the West Coast's creative spirit… Full Article Arts & Culture
nl Cloverland, Wash: The only original building left in this briefly booming orchard town in Asotin County is its well-preserved garage By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 Though a sign on Washington State Route 129 points you in the right direction, driving the nearly 12 miles along Cloverland Road to arrive at the Cloverland Garage in Asotin County can make you feel like you're, well, chasing ghosts… Full Article Arts & Culture
nl Scouting the Inland Northwest's college hoops programs for the 2024-25 season By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 WASHINGTON STATE MEN… Full Article Sports
nl Discover five Inland Northwest ghost towns where the past still eerily echoes By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 As early settlers flocked to the American West to extract the land's rich resources, small towns spread across the landscape… Full Article Arts & Culture
nl Inland Northwest tribes are using technology to track young salmon in hopes of returning runs to the Columbia and Spokane rivers By www.inlander.com Published On :: Thu, 12 May 2022 01:30:00 -0700 It starts raining just as two trucks hauling juvenile salmon arrive near the end of a gravel road at Chief Joseph Dam in the Central Washington town of Bridgeport on Friday, May 6… Full Article News/Local News
nl Meet the Mild Riders, Spokane's chillest (and only) scooter gang By www.inlander.com Published On :: Thu, 19 May 2022 01:30:00 -0700 Whizzing through West Central Spokane on the back of a scooter, the wind whipping around your face, offers a new perspective to getting around town… Full Article Culture/Arts & Culture
nl Fentanyl is flooding into the Inland Northwest, triggering a deadlier phase of the opioid crisis By www.inlander.com Published On :: Thu, 30 Sep 2021 01:40:00 -0700 Allan didn't know it was fentanyl… Full Article News/Local News
nl The Childhood Cancer Coalition eases the disease's burden on Inland Northwest families, one kindness at a time By www.inlander.com Published On :: Thu, 22 Aug 2024 01:30:00 -0700 On Meagan Glubrecht's right forearm is an unmistakable tattoo… Full Article Give Guide
nl Light A Lamp works to support Inland Northwest students who struggle with anxiety and depression, one act of kindness at a time By www.inlander.com Published On :: Thu, 22 Aug 2024 01:30:00 -0700 Angella Southerly believes that a single act of kindness, no matter how small, has the power to change someone's life… Full Article Give Guide
nl Annual Manual 2024: Explore the Inland Northwest By www.inlander.com Published On :: Mon, 23 Sep 2024 01:30:00 -0700 Think about the last time you went on a trip, whether halfway around the globe or just an hour or two away by car… Full Article Annual Manual
nl After an Inlander article about her links to conspiracy theory websites, Rep. Jenny Graham responds with profanity, threats and another conspiracy website By www.inlander.com Published On :: Mon, 14 Sep 2020 13:40:49 -0700 State Rep. Jenny Graham (R-Spokane) called me on my cellphone the day the Inlander published my story about her unwittingly linking to conspiracy theory posts on Facebook. I called her back immediately — while she was still leaving a voicemail — and was greeted with two blasts of profanity. "You cocksucker!… Full Article News/Local News
nl I've been to my fair share of breweries, but #steamwhistle ranks right up there. There's not many other breweries that only do *one thing* but do it so well. By www.flickr.com Published On :: Wed, 07 Dec 2016 14:22:16 -0800 marusin posted a photo: via Instagram ift.tt/2hkUMfs Full Article
nl Janet Mock Rants Against Hollywood at 'Pose' Premiere After Only Getting Paid $40,000 Per Episode By www.aceshowbiz.com Published On :: Sat, 01 May 2021 08:00:01 +0000 During her speech, the producer and director of the show also apologizes to boyfriend Angel Bismark Curiel as she admits to having cheated on him during the show's production. Full Article tv Pose Janet Mock
nl Olivia Rodrigo, Lil Nas X and Others Tapped to Appear in Final Episodes of 'SNL' Season 46 By www.aceshowbiz.com Published On :: Tue, 04 May 2021 06:28:53 +0000 Meanwhile, 'The Predator' actor Keegan-Michael Key and 'The Queen's Gambit' star Anya Taylor-Joy have been set to host the final episodes of the NBC show's current season. Full Article tv Saturday Night Live
nl Elon Musk Plays Down Rumors of 'SNL' Cast's Uproar Over His Hosting Gig By www.aceshowbiz.com Published On :: Wed, 05 May 2021 15:00:01 +0000 When asked how rehearsals with the stars of the NBC sketch show have been going in light of the alleged protest, the Tesla CEO says it's all 'much ado about nothing.' Full Article tv Saturday Night Live Elon Musk
nl Pete Davidson 'Really Excited' for Elon Musk's 'SNL' Hosting Gig Despite Fellow Cast's Criticisms By www.aceshowbiz.com Published On :: Wed, 05 May 2021 23:30:01 +0000 The 'Trainwreck' actor is looking forward to the upcoming episode which will see the Tesla boss as a host although some of his co-stars are seemingly not happy with the casting. Full Article tv Saturday Night Live Pete Davidson;Elon Musk
nl NLE Choppa Addresses Viral Video of Him and His Crew Jumping a Fan By www.aceshowbiz.com Published On :: Tue, 04 May 2021 08:21:29 +0000 Taking to his Twitter account, the 'Walk Em Down' rapper plays down the fact that he got punched by the said fan even though all of his crew helped him during the physical altercation at the beach. Full Article celebrity NLE Choppa
nl Julianna Margulies Always Loses to Son in Cooking Contest as She Enlists Neighbors as Judges By www.aceshowbiz.com Published On :: Wed, 05 May 2021 00:30:01 +0000 The former 'ER' actress reveals she spent Covid-19 lockdown having a bake-off with her son and the judges that involve their neighbors always love the kid's cookies more. Full Article celebrity Julianna Margulies
nl Elon Musk Plays Down Rumors of 'SNL' Cast's Uproar Over His Hosting Gig By www.aceshowbiz.com Published On :: Wed, 05 May 2021 15:00:01 +0000 When asked how rehearsals with the stars of the NBC sketch show have been going in light of the alleged protest, the Tesla CEO says it's all 'much ado about nothing.' Full Article tv Saturday Night Live Elon Musk
nl Pete Davidson 'Really Excited' for Elon Musk's 'SNL' Hosting Gig Despite Fellow Cast's Criticisms By www.aceshowbiz.com Published On :: Wed, 05 May 2021 23:30:01 +0000 The 'Trainwreck' actor is looking forward to the upcoming episode which will see the Tesla boss as a host although some of his co-stars are seemingly not happy with the casting. Full Article tv Saturday Night Live Pete Davidson;Elon Musk
nl Hugh Jackman Enlists NY Cop to Pressure Ryan Reynolds Into Getting Him in 'Deadpool 3' By www.aceshowbiz.com Published On :: Mon, 03 May 2021 08:14:14 +0000 In a video posted on his social media accounts, an officer named John Dobkowski tells the 'Deadpool' star to get the 'Logan' actor in the upcoming movie, or else he will be ticketing Reynolds. Full Article movie Deadpool 3 Hugh Jackman;Ryan Reynolds
nl AppleVis Unleashed April 2023: A Little Bank By www.applevis.com Published On :: Thu, 27 Apr 2023 17:20:25 +0000 In this month's edition of AppleVis Unleashed, Thomas Domville and Mike Malarsie discuss recent Apple news and other topics of interest. Topics featured in this episode include:Here Comes the WWDC 2023 (00:04:20)The Musical Chairs Continues for the iPhone 15 Rumors (00:12:50)Apple Turns on HomePod's Smoke Alarm Recognition (00:18:40)Move Over! There is a New Bank in Town (00:23:18(Subscription Fatigue (00:33:18(Upcoming Apple Watch OS Getting a Big Interface Changes (00:41:09)More Leaks in What We Could See in the Upcoming iOS 17 (00:43:06)What's in this month AppleVis News (00:57:42) Closing (01:00:36)Links:Apple Announces WWDC 2023 Event Taking Place June 5 to 9Apple's AR/VR Headset Will Be Able To Run 'Hundreds of Thousands' of iPad Apps, Report SaysiPhone 15 Pro Now Expected to Feature Two-Button Design for Volume, Mute Switch Still Replaced by ButtoniPhone 15 Pro 'Action' Button to Replace Role of Volume Buttons When Performing a Power Off/Force RestartApple turns on HomePod's smoke alarm recognitionApple Card Savings Account Available Starting Today With 4.15% Interest RateApple Pay Later LaunchesVoice Dream Reader for iOS is now $59.99/yearwatchOS 10 Rumored to Feature New Home Screen Layout With FoldersApple will make big interface changes in watchOS 10A more sane iOS 17 compatibility list has been leakediOS 17 Rumored to Improve Search, Dynamic Island, Control Center, and MoreAlleged iOS 17 leak offers a vague rundown of new features for iPhone usersiOS 17 Rumored to Feature Wallet and Find My Improvements, macOS 14 to Be Minor UpdatePurple FridayAnnouncing Timecrest Rewrite coming April 25, 2023!If you have feedback or questions for the Unleashed team, you can reach them by… Full Article
nl Introducing Pride Counseling: An iOS App That Provides Online Therapy for the LGBTQ+ Community By www.applevis.com Published On :: Mon, 08 May 2023 08:21:38 +0000 In this episode, Ida introduces us to Pride Counseling, an iOS app that provides access to the company's online therapy platform specifically designed for the LGBTQ+ community. She discusses the app's features, such as live chat and video calls with licensed professionals who specialize in LGBTQ+ issues. Ida explains how Pride Counseling provides personalized therapy that is convenient and discreet. Full Article