Farnesol, a fungal signaling molecule, alters lipid synthesis in dendritic cells, causing mitochondrial dysfunction and decreased inflammatory responding.

Gio Gonzalez threw strikes on Thursday night – 78 to be exact, on 112 pitches — keying his one-hit work over eight dominant innings in the Nats’ 8-1 victory over the Reds. Gonzalez (2-1), the Nats’ starter most susceptible to wildness, had walked 11 in 20 innings, lasting no more than six innings in any of his previous four starts. But with the lead from the third inning on, Gonzalez was able to attack.

Apple is reportedly working on its first smart home camera with a possible launch in 2026, according to Apple analyst Ming-Chi Kuo.

The post Report: Apple to Release First Smart Home Camera in 2026 appeared first on Thurrott.com.

The left tries to find its footing before Trump takes power again. by Hannah Krieg

Photography by Ananya Mishra

Seattle lefties gathered at the Space Needle this weekend to hype themselves up for what promises to be a rough four years under a second Trump administration. Speakers acknowledged that the future feels foggy, and that it's unclear what the first fights will be.

Unlike many of the protests around the country, Seattle’s wasn’t organized by the Women’s March or driven by Trump’s attacks on abortion, women, and LGBTQ rights. But it was an important opportunity for local activists to start saying some of our new realities out loud: that we’re about to have a president that seems determined to level Gaza, deport both documented and undocumented immigrants, undermine worker power, and continue to allow cops to kill with impunity. 

Perhaps unsurprisingly, though, not everyone left feeling hyped. The protest lacked the same energy that they harnessed in the wake of Trump’s election eight years ago, or even some of the other protests around the country this weekend. The calls to action—“resist, organize, fight”—felt too vague, especially when the left has had so little success organizing on the national stage. “It felt like we went from resistance to resignation and that this was just perfunctory," one attendee said. 

But we’re also only six days into this new paradigm. And we captured what promises to be the first protest of many as Seattle’s left finds their footing, and their energy. 

MONDAY

5a, 7a, 5p - Democracy Now!
6a, 8a, 3p - Thom Hartmann Program
6p - Local Public Affairs

TUESDAY

5a, 7a, 5p - Democracy Now!
6a, 8a, 3p - Thom Hartmann Program
6p - The Bioneers
6:30p - Sea Change Radio

WEDNESDAY

5a, 7a, 5p - Democracy Now!
6a, 8a, 3p - Thom Hartmann Program
6p - Law and Disorder

THURSDAY

5a, 7a, 5p - Democracy Now!
6a, 8a, 3p - Thom Hartmann Program
4p - Healthy Living with The Doctors
6p - CounterSpin
6:30p - Between the Lines

FRIDAY

5a, 7a, 5p - Democracy Now!
6a, 8a, 3p - Thom Hartmann Program
6p - Left, Right & Center

SUNDAY

7a - Alternative Radio
8a - New Dimensions
9a - Travel with Rick Steves

Every once in a while, there is a film that is just soul shatteringly good…

Don't even try to deny it, you're a total sucker for an animated children's movie…

When I began thinking about the relationship between neighborhoods and food in Spokane, we were still in COVID lockdown and I hadn't been out to eat in over a year…

"There's a million things I want to do," says Ben Joyce…

In 1914, English composer Gustav Holst began writing what would become The Planets, a seven-movement orchestral suite inspired by the seven planets in the solar system (minus Earth) and each planet's astrological character…

marusin posted a photo:

via Instagram ift.tt/2g4kYir

In a surprising twist, the upcoming Netflix series is executive produced by Robert Downey, Jr., who is famously known as Iron Man in Marvel Cinematic Universe, and his wife Susan Downey.

The network shares a look at Princess Rhaenyra Targaryen, Prince Daemon Targaryen, Lord Corlys Velaryon, a.k.a. The Sea Snake, as well as Otto Hightower and his daughter Alicent.

Johnny Borrell and his original bandmates announce a reunion to work on new music and perform a livestream concert, ten years after they went their separate ways.

Joining the rapper's new album 'A Gangsta's Pain' as the new entry in this week's chart is Eric Church's 'Soul' as it debuts at No. 4 with 53,000 equivalent album units earned.

The 'Carol' star has written a heartfelt open letter as part of Farm Sanctuary's campaign commemorating the day that is specifically dedicated to mothers and maternal figures.

Our new blog has been launched today. Stay focused on it and we will try to keep you informed. You can read new posts on this blog via the RSS feed.

The Little Mix member debuts her burgeoning baby bump as she announces to her social media followers that she is expecting her first child with fiance Andre Gray.

The estate of the late King of Pop describes the triumph in a court battle against the Internal Revenue Service as 'a huge, unambiguous victory' for the star's children.

The 'Carol' star has written a heartfelt open letter as part of Farm Sanctuary's campaign commemorating the day that is specifically dedicated to mothers and maternal figures.

The network shares a look at Princess Rhaenyra Targaryen, Prince Daemon Targaryen, Lord Corlys Velaryon, a.k.a. The Sea Snake, as well as Otto Hightower and his daughter Alicent.

The promo that also celebrates the past MCU movies offers a look at Angelina Jolie's Thena, Richard Madden's Icarus, Kumail Nanjiani's Kingo and Gemma Chan's Sersi among other Eternals.

Employment and training opportunities for local people.

Charter 400 project marks anniversary of historic landmark.

Simon Hale watches the Birmingham Hippodrome production of Hairspray.

A poignant new free exhibition, Last Post: Remembering the First World War, will explore the effect of the events of 1914-18 on the Post Office, its people and the contribution of postal communications to the war effort.

The unique remains of a First World War Handley Page O/400 bomber aircraft have been saved by a team from the RAF Museum.

First participants confirmed through the Birmingham Weekender in Digbeth Open Call.

WMCA bosses appointed as champions to tackle violence against women on public transport.

Curry competition to raise funds for Birmingham charity.

War and Craig Charles to perform in the park.

Richard Lutz reports on a step forward in opening the Moseley/Kings Heath train line.

Noel Tata, newly appointed chairman of Tata Trusts, has joined the board of Tata Sons as a nominee director. This marks the first time since 2011 that a Tata family member holds positions on both boards concurrently. Tata Trusts, with its 66% stake, is the largest shareholder in Tata Sons, the holding company of the Tata Group.

India's retail inflation rose to 6.21 percent in October. This is a significant increase from September's 5.49 percent. Food prices are the main reason for this surge. This is the first time since August that inflation has gone beyond the Reserve Bank of India's 6 percent limit. The rise in onion prices is a major concern.

Apple established a new subsidiary in India, Apple Operations India, marking its first direct presence in the country. This subsidiary will focus on research, design, testing, and providing support to third-party manufacturers. This move signifies Apple's commitment to expanding its operational footprint in India beyond assembly and sales.

FirstCry’s IPO size will be the same, as per the IPO papers. It intends to raise $218 million (about Rs 1,815 crore) in primary funding through issuance of new shares and divestment of 54 million shares from existing investors.

FirstCry's CEO Maheshwari saw a 49% compensation drop. The company plans an IPO, approaching SEBI. Employee benefits decreased, with a Rs 23,000 crore valuation and an expected IPO of $3.5-3.75 billion.

FirstCry, a baby and mother care product retailer, will list likely at a $3-3.5 billion valuation, sources in the know told ET. FirstCry's IPO will be the second major new-age company to debut on Dalal Street this year, after Ola Electric. The company's offer size remains the same as mentioned in its draft papers.

FirstCry reported a 15% increase in operating revenue to Rs 6,481 crore and reduced losses by 34% in FY24. The Pune-based firm's international business, which is seeing faster growth than domestic operations, reported a revenue of Rs 753 crore, growing by over 50%. The firm plans to use a significant portion of its IPO proceeds for expansion in Saudi Arabia.

The IPO of Brainbees Solution, known for its kidswear brand FirstCry, will open on August 6. It comprises a fresh issue of Rs 1,666 crore and an OFS of up to 5.4 crore shares. The anchor investor round will commence on August 5, a day before the IPO. The price band will be announced later in the week, as per the company's red herring prospectus RHP filed with Sebi.

Founded by Supam Maheshwari and his colleague from a previous business, Amitava Saha, FirstCry has been the darling of investors which include SoftBank, Tata Sons Chairman Emeritus Ratan Tata, Premji Invest, Mahindra & Mahindra and TPG Growth.

We'll continue to invest in our brand, technology, products, and grow our offline online touchpoints. We are going to open around 350 stores over the next three years and grow our multi-channel competitive strengths. We will also enhance our in-house brands and their distribution through pharmacies and grocery stores. We also plan to invest in manufacturing, international markets and Globalbees, our brand aggregator platform,Supam Maheshwari, cofounder and CEO of FirstCry said.

According to a circular upload on BSE, Brainbees Solutions allotted 4.05 crore equity shares to 71 funds at Rs 465 apiece, which is also the upper end of the price band. This takes the transaction size to Rs 1,886 crore. The IPO, with a price band of Rs 440-465 a share, will open for public subscription on August 6 and close on August 8.

“Subscription, oversubscription, listing gains, do not matter much to me, personally. What matters is this milestone of launching the IPO, which gives a feeling of accomplishment to all our families, and extended families. I am sure performance will always proceed when it comes to the outcome in terms of numbers on the stock market. So, that is okay,” Supam Maheshwari, cofounder and CEO of the Pune-based company, told ET on the sidelines of the listing ceremony.

Floods in the UAE and early Eid, which saw festival season purchases being advanced to early April, hit order volumes for Brainbees Solutions, the parent firm of the baby and mother care product retailer. However, order volumes are now back on track, said CEO Supam Maheshwari.

Shares of FirstCry fell 4.5% after the GST department initiated an investigation at its Mumbai head office and Pune warehouse. The company assured normal operations, with no details on alleged violations.

Our new blog has been launched today. Stay focused on it and we will try to keep you informed. You can read new posts on this blog via the RSS feed.

Our new blog has been launched today. Stay focused on it and we will try to keep you informed. You can read new posts on this blog via the RSS feed.

Our new blog has been launched today. Stay focused on it and we will try to keep you informed. You can read new posts on this blog via the RSS feed.

Monetization is not the only profit you can get from podcasting! Here's why I think you should put P.R.O.F.I.T. first in every aspect of your podcast.

The post Why You Should Put Podcasting P.R.O.F.I.T. First first appeared on The Audacity to Podcast.